{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T05:25:28Z","timestamp":1778390728763,"version":"3.51.4"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2016,2,17]],"date-time":"2016-02-17T00:00:00Z","timestamp":1455667200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Pharmacol"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1007\/s00228-016-2022-4","type":"journal-article","created":{"date-parts":[[2016,2,17]],"date-time":"2016-02-17T02:28:51Z","timestamp":1455676131000},"page":"631-639","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Hospital re-admission associated with adverse drug reactions in patients over the age of 65\u00a0years"],"prefix":"10.1007","volume":"72","author":[{"given":"Laurent","family":"Hauviller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Eyvrard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Val\u00e9rie","family":"Garnault","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Rousseau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Molinier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Louis","family":"Montastruc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haleh","family":"Bagheri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,2,17]]},"reference":[{"key":"2022_CR1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1136\/bmj.329.7456.15","volume":"329","author":"M Pirmohamed","year":"2004","unstructured":"Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ, Farrar K, Park K, Breckenridge AM (2004) Adverse drug reactions as a cause of admission to hospital: prospective analysis of 18820 patients. Br Med J 329:15\u201319","journal-title":"Br Med J"},{"key":"2022_CR2","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1136\/bmj.320.7241.1036","volume":"320","author":"P Pouyanne","year":"2000","unstructured":"Pouyanne P, Haramburu F, Imbs JL, Begaud B (2000) Admissions to hospital caused by adverse drug reactions: cross sectional incidence study. Br Med J 320:1036","journal-title":"Br Med J"},{"key":"2022_CR3","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1345\/aph.1L037","volume":"42","author":"C Kongkaew","year":"2008","unstructured":"Kongkaew C, Noyce PR, Ashcroft DM (2008) Hospital admissions associated with adverse drug reactions: a systematic review of prospective observational studies. Ann Pharmacother 42:1017\u20131025","journal-title":"Ann Pharmacother"},{"key":"2022_CR4","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s40264-015-0281-0","volume":"38","author":"JC Bouvy","year":"2015","unstructured":"Bouvy JC, De Bruin ML, Koopmanschap MA (2015) Epidemiology of adverse drug reactions in Europe: a review of recent observational studies. Drug Saf 38:437\u2013453","journal-title":"Drug Saf"},{"key":"2022_CR5","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1007\/s00520-014-2160-0","volume":"22","author":"A Chan","year":"2014","unstructured":"Chan A, Soh D, Ko Y, Yu-Chu H, Chiang J (2014) Characteristics of unplanned hospital admissions due to drug-related problems in cancer patients. Support Care Cancer 22:1875\u20131881","journal-title":"Support Care Cancer"},{"key":"2022_CR6","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.jpainsymman.2010.11.014","volume":"42","author":"V Miranda","year":"2011","unstructured":"Miranda V, Fede A, Nobuo M, Ayres V, Giglio A, Miranda M, Riechelmann RP (2011) Adverse drug reactions and drug interactions as causes of hospital admission in oncology. J Pain Symptom Manag 42:342\u2013353","journal-title":"J Pain Symptom Manag"},{"key":"2022_CR7","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/pds.1565","volume":"17","author":"CS Hooft van der","year":"2008","unstructured":"van der Hooft CS, Dieleman JP, Siemes C, Aarnoudse AJ, Verhamme KM, Stricker BH, Sturkenboom MC (2008) Adverse drug reaction-related hospitalisations: a population-based cohort study. Pharmacoepidemiol Drug Saf 17:365\u2013371","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"2022_CR8","doi-asserted-by":"crossref","first-page":"2752","DOI":"10.1136\/bmj.a2752","volume":"338","author":"M Zhang","year":"2009","unstructured":"Zhang M, Holman DJ, Price SD, Sanfilipo FM, Preen DB, Bulsara MK (2009) Comorbidity and repeat admission to hospital for adverse drug reactions in older adults: retrospective cohort study. Br Med J 338:2752","journal-title":"Br Med J"},{"key":"2022_CR9","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1001\/jama.296.15.1858","volume":"296","author":"DS Budnitz","year":"2006","unstructured":"Budnitz DS, Pollock DA, Weidenbach KN, Mendelsohn AB, Schroeder TJ, Annest JL (2006) National surveillance of emergency department visits for outpatient adverse drug events. JAMA 296:1858\u20131866","journal-title":"JAMA"},{"key":"2022_CR10","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/fcp.12088","volume":"29","author":"A Benard-Laribi\u00e8re","year":"2015","unstructured":"Benard-Laribi\u00e8re A, Miremont-SalameG P-PMC, Noize P, Harmburu F (2015) Incidence of hospital admissions due to adverse drug reactions in France: the EMIR study. Fundam Clin Pharmacol 29:106\u2013111","journal-title":"Fundam Clin Pharmacol"},{"key":"2022_CR11","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1111\/j.1365-2125.2010.03751.x","volume":"70","author":"EC Davies","year":"2010","unstructured":"Davies EC, Green CF, Mottram DR, Rowe PH, Pirmohamed M (2010) Emergency re-admissions to hospital due to adverse drug reactions within 1\u00a0year of the index admission. Br J Clin Pharmacol 70:749\u2013755","journal-title":"Br J Clin Pharmacol"},{"key":"2022_CR12","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/jgs.12037","volume":"61","author":"D Bonnet-Zamponi","year":"2013","unstructured":"Bonnet-Zamponi D, d\u2019Arailh L, Konrat C, Delpierre S, Lieberherr D, Lemaire A, Tubach F (2013) Drug-related readmissions to medical units of older adults discharged from acute geriatric units: optimization of medication in AGE Multicenter\u2014results of the randomized controlled trial. J Am Geriatr Soc 61:113\u2013121","journal-title":"J Am Geriatr Soc"},{"key":"2022_CR13","unstructured":"Hauviller L, Eyvrard F, Garnault V, Montastruc JL, Bagheri H (2012) Estimation of re-admission rate to hospital in old people due to adverse Drug reactions: Data in Toulouse University Hospital. Fundam Clin Pharmacol (suppl 1):23"},{"key":"2022_CR14","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1002\/pds.2044","volume":"19","author":"A Weill","year":"2010","unstructured":"Weill A, Pa\u00efta M, Tuppin P, Fagot JP, Neumann A, Simon D, Ricordeau P, Montastruc JL, Allemand H (2010) Benfluorex and valvular heart disease: a cohort study of a million people with diabetes mellitus. Pharmacoepidemiol Drug Saf 19:1256\u20131262","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"2022_CR15","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1007\/s40264-014-0149-8","volume":"37","author":"M Gourbil","year":"2014","unstructured":"Gourbil M, Grandvuillemin A, Beyens MN, Massy N, Gras V, D\u2019Amico A, Miremont-Salam\u00e9 G, Petitpain N (2014) Thromboembolic events in women exposed to hormonal contraception or cyproterone acetate in 2012: a cross-sectional observational study in 30 French public hospitals. Drug Saf 37:262\u2013289","journal-title":"Drug Saf"},{"key":"2022_CR16","unstructured":"World Health Organization 2010 International statistical classification of diseases and related health problems, 10th version. Available at: www.who.int\/classifications\/icd ."},{"key":"2022_CR17","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1365-2125.2006.02633.x","volume":"62","author":"S Lugardon","year":"2006","unstructured":"Lugardon S, Desboeuf K, Fernet P, Montastruc JL, Lapeyre-Mestre M (2006) Using a capture-recapture method to assess the frequency of adverse drug reactions in a French university. Br J Clin Pharmacol 62:225\u2013231","journal-title":"Br J Clin Pharmacol"},{"key":"2022_CR18","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/S0140-6736(00)02799-9","volume":"356","author":"E IR","year":"2000","unstructured":"IR E, JK A (2000) Adverse drug reactions: definitions, diagnosis, and management. Lancet 356:1255\u20131259","journal-title":"Lancet"},{"key":"2022_CR19","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1016\/j.jclinepi.2004.03.012","volume":"57","author":"V Sundararajan","year":"2004","unstructured":"Sundararajan V, Henderson T, Perry C, Muggivan A, Quan H, Ghali WA (2004) New ICD-10 version of the Charlson comorbidity index predicted in-hospital mortality. J Clin Epidemiol 57:1288\u20131294","journal-title":"J Clin Epidemiol"},{"key":"2022_CR20","unstructured":"ATC\/DDD Index 2013 (n.d.). Available: http:\/\/www.whocc.no\/atc_ddd_index\/ ."},{"key":"2022_CR21","first-page":"111","volume":"40","author":"B B\u00e9gaud","year":"1985","unstructured":"B\u00e9gaud B, Evreux JC, Jouglard J, Lagier G (1985) Imputation of the unexpected or toxic effects of drugs. Actualization of the Method Used in France Therapie 40:111\u2013118","journal-title":"Actualization of the Method Used in France Therapie"},{"key":"2022_CR22","doi-asserted-by":"crossref","first-page":"39","DOI":"10.2515\/therapie:2005005","volume":"60","author":"P Olivier","year":"2005","unstructured":"Olivier P, Caron J, Haramburu F, Imbs J-L, Jonville-B\u00e9ra A-P, Lagier G, et al. (2005) Validation of a measurement scale: example of a French adverse drug reactions preventability scale. Therapie 60:39\u201345","journal-title":"Therapie"},{"key":"2022_CR23","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1345\/aph.1Q529","volume":"46","author":"KC Sikdar","year":"2012","unstructured":"Sikdar KC, Dowden J, Alaghehbandan R, MacDonald D, Peter P, Gadag V (2012) Adverse drug reactions in elderly hospitalized patients: a 12-year population-based retrospective cohort study. Ann Pharmacother 46:960\u2013971","journal-title":"Ann Pharmacother"},{"key":"2022_CR24","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.revmed.2014.11.016","volume":"36","author":"H Chaye","year":"2015","unstructured":"Chaye H, Bernard M, Tubery M, Rousseau V, Ecoiffier M, Montastruc JL, Bagheri H (2015) Hospital readmission induced by adverse drug reaction: a pilot study in a post-emergency unit of a French university hospital. Rev Med Int 36:450\u2013456","journal-title":"Rev Med Int"},{"key":"2022_CR25","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/pds.1154","volume":"15","author":"M Euler Von","year":"2006","unstructured":"Von Euler M, Eliasson E, \u00d6hl\u00e9n G, Bergman U (2006) Adverse drug reactions causing hospitalization can be monitored from computerized medical records and thereby indicate the quality of drug utilization. Pharmacoepidemiol Drug Saf 15:179\u2013184","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"2022_CR26","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1046\/j.1532-5415.2002.50607.x","volume":"50","author":"G Onder","year":"2002","unstructured":"Onder G, Pedone C, Landi F, Cesari M, Della Vedova C, Bernabei R, et al. (2002) Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA). J Am Geriatr Soc 50:1962\u20131968","journal-title":"J Am Geriatr Soc"},{"key":"2022_CR27","doi-asserted-by":"crossref","first-page":"429","DOI":"10.2165\/00002018-200932050-00006","volume":"32","author":"AP Jonville-B\u00e9ra","year":"2009","unstructured":"Jonville-B\u00e9ra AP, Saissi H, Bensouda-Grimaldi L, Beau-Salinas F, Cissoko H, Giraudeau B, Autret-Leca E (2009) Avoidability of adverse drug reactions spontaneously reported to a French regional drug monitoring centre. Drug Saf 32:429\u2013440","journal-title":"Drug Saf"},{"key":"2022_CR28","doi-asserted-by":"crossref","first-page":"477","DOI":"10.2515\/therapie\/2015029","volume":"70","author":"L Kanagaratnam","year":"2015","unstructured":"Kanagaratnam L, Abou Taam M, Heng M, De Boissieu P, Roux MP, Trenque T (2015) Serious adverse drug reaction and their preventability in the elderly over 65\u00a0years. Therapie 70:477\u2013484","journal-title":"Therapie"},{"key":"2022_CR29","unstructured":"R\u00e9partition des s\u00e9jours dans les \u00e9tablissements de soins de courte dur\u00e9e MCO selon le sexe, l\u2019\u00e2ge des patients et la pathologie trait\u00e9e. (2010). Available at: http:\/\/www.datadrees.sante.gouv.fr\/tableViewer\/table\/View.aspx?Reportld=1265"},{"key":"2022_CR30","first-page":"137","volume":"55","author":"B Detournay","year":"2000","unstructured":"Detournay B, Fagnani F, Pouyanne P, Haramburu F, Begaud B, Welsch M, Imbs JL (2000) Cost of hospitalizations for adverse drug effects. Therapie 55:137\u2013139","journal-title":"Therapie"}],"container-title":["European Journal of Clinical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00228-016-2022-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00228-016-2022-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00228-016-2022-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T12:49:16Z","timestamp":1558702156000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00228-016-2022-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,17]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["2022"],"URL":"https:\/\/doi.org\/10.1007\/s00228-016-2022-4","relation":{},"ISSN":["0031-6970","1432-1041"],"issn-type":[{"value":"0031-6970","type":"print"},{"value":"1432-1041","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,17]]}}}