{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T13:06:23Z","timestamp":1648645583410},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2018,1,23]],"date-time":"2018-01-23T00:00:00Z","timestamp":1516665600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Pharmacol"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1007\/s00228-018-2417-5","type":"journal-article","created":{"date-parts":[[2018,1,23]],"date-time":"2018-01-23T13:01:47Z","timestamp":1516712507000},"page":"675-677","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Subtherapeutic valproic acid plasma concentrations under concomitant dipyrone therapy in an epilepsy patient\u2014a case report"],"prefix":"10.1007","volume":"74","author":[{"given":"Benedict","family":"Morath","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Green","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Zaradzki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Heid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Karck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Hoppe-Tichy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,1,23]]},"reference":[{"issue":"10","key":"2417_CR1","doi-asserted-by":"publisher","first-page":"669","DOI":"10.2165\/00023210-200216100-00003","volume":"16","author":"W Loscher","year":"2002","unstructured":"Loscher W (2002) Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy. CNS drugs 16(10):669\u2013694. \nhttps:\/\/doi.org\/10.2165\/00023210-200216100-00003","journal-title":"CNS drugs"},{"issue":"15","key":"2417_CR2","doi-asserted-by":"publisher","first-page":"2063","DOI":"10.2165\/11318850-000000000-00000","volume":"69","author":"GS Mahli","year":"2009","unstructured":"Mahli GS, Adams D, Cahill CM, Dodd S, Berk M (2009) The management of individuals with bipolar disorder: a review of the evidence and its integration into clinical practice. Drugs 69(15):2063\u20132101. \nhttps:\/\/doi.org\/10.2165\/11318850-000000000-00000","journal-title":"Drugs"},{"issue":"2","key":"2417_CR3","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1097\/01.wnf.0000154221.37887.73","volume":"28","author":"J Fleming","year":"2005","unstructured":"Fleming J, Chetty M (2005) Psychotropic drug interactions with valproate. Clin Neuropharmacol 28(2):96\u2013101. \nhttps:\/\/doi.org\/10.1097\/01.wnf.0000154221.37887.73","journal-title":"Clin Neuropharmacol"},{"issue":"4","key":"2417_CR4","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.clineuro.2010.01.002","volume":"112","author":"L Tan","year":"2010","unstructured":"Tan L, Yu JT, Sun YP, Ou JR, Song JH, Yu Y (2010) The influence of cytochrome oxidase CYP2A6, CYP2B6, and CYP2C9 polymorphisms on the plasma concentrations of valproic acid in epileptic patients. Clin Neurol Neurosurg 112(4):320\u2013323. \nhttps:\/\/doi.org\/10.1016\/j.clineuro.2010.01.002","journal-title":"Clin Neurol Neurosurg"},{"key":"2417_CR5","doi-asserted-by":"publisher","unstructured":"Hiemke C, Bergemann N, Clement HW, Conca A, Deckert J, Domschke K, Eckermann G, Egberts K, Gerlach M, Greiner C, Grunder G, Haen E, Havemann-Reinecke U, Hefner G, Helmer R, Janssen G, Jaquenoud E, Laux G, Messer T, Mossner R, Muller MJ, Paulzen M, Pfuhlmann B, Riederer P, Saria A, Schoppek B, Schoretsanitis G, Schwarz M, Gracia MS, Stegmann B, Steimer W, Stingl JC, Uhr M, Ulrich S, Unterecker S, Waschgler R, Zernig G, Zurek G, Baumann P (2017) Consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology: update 2017. Pharmacopsychiatry. \nhttps:\/\/doi.org\/10.1055\/s-0043-116492","DOI":"10.1055\/s-0043-116492"},{"issue":"3","key":"2417_CR6","doi-asserted-by":"publisher","first-page":"216","DOI":"10.2165\/00003088-199528030-00004","volume":"28","author":"M Levy","year":"1995","unstructured":"Levy M, Zylber-Katz E, Rosenkranz B (1995) Clinical pharmacokinetics of dipyrone and its metabolites. Clin Pharmacokinet 28(3):216\u2013234. \nhttps:\/\/doi.org\/10.2165\/00003088-199528030-00004","journal-title":"Clin Pharmacokinet"},{"key":"2417_CR7","unstructured":"European Medicines Agency. List of nationally authorised medicinal products: active substance: metamizole. \nhttp:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Periodic_safety_update_single_assessment\/2016\/10\/WC500214536.pdf\n\n. Accessed 22.09.2017"},{"key":"2417_CR8","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-662-47186-9","volume-title":"Arzneiverordnungsreport 2015","author":"U Schwabe","year":"2015","unstructured":"Schwabe U, Paffrath D, B\u00f6ger RH, Schmidt G (2015) Arzneiverordnungsreport 2015. Springer, Berlin Heidelberg. \nhttps:\/\/doi.org\/10.1007\/978-3-662-47186-9"},{"key":"2417_CR9","doi-asserted-by":"publisher","unstructured":"Zylber-Katz E, Granit L, Levy M (1985) Plasma protein binding of dipyrone metabolites in man. Eur J Clin Pharmacol (1985) 29 (1): 67\u201371. doi:\nhttps:\/\/doi.org\/10.1007\/BF00547371","DOI":"10.1007\/BF00547371"},{"issue":"3","key":"2417_CR10","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1038\/sj.clpt.6100138","volume":"82","author":"T Saussele","year":"2007","unstructured":"Saussele T, Burk O, Blievernicht JK, Klein K, Nussler A, Nussler N, Hengstler JG, Eichelbaum M, Schwab M, Zanger UM (2007) Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole. Clin Pharmacol Ther 82(3):265\u2013274. \nhttps:\/\/doi.org\/10.1038\/sj.clpt.6100138","journal-title":"Clin Pharmacol Ther"},{"issue":"6","key":"2417_CR11","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1111\/j.1365-2125.2012.04304.x","volume":"74","author":"WJ Qin","year":"2012","unstructured":"Qin WJ, Zhang W, Liu ZQ, Chen XP, Tan ZR, Hu DL, Wang D, Fan L, Zhou HH (2012) Rapid clinical induction of bupropion hydroxylation by metamizole in healthy Chinese men. Br J Clin Pharmacol 74(6):999\u20131004. \nhttps:\/\/doi.org\/10.1111\/j.1365-2125.2012.04304.x","journal-title":"Br J Clin Pharmacol"},{"issue":"2","key":"2417_CR12","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1093\/toxsci\/kfl096","volume":"94","author":"TK Kiang","year":"2006","unstructured":"Kiang TK, Ho PC, Anari MR, Tong V, Abbott FS, Chang TK (2006) Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1\/*1 genotype. Toxicol Sci 94(2):261\u2013271. \nhttps:\/\/doi.org\/10.1093\/toxsci\/kfl096","journal-title":"Toxicol Sci"},{"key":"2417_CR13","doi-asserted-by":"publisher","unstructured":"Martin-Facklam M, Drewe J, Haefeli WE (2000) Drug interactions with the cytochrome P-450 system. Dtsch Med Wochenschr 125 (3):63\u201367. doi:\nhttps:\/\/doi.org\/10.1055\/s-2007-1023908","DOI":"10.1055\/s-2007-1023908"}],"container-title":["European Journal of Clinical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00228-018-2417-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00228-018-2417-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00228-018-2417-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T08:58:35Z","timestamp":1523350715000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00228-018-2417-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,23]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["2417"],"URL":"https:\/\/doi.org\/10.1007\/s00228-018-2417-5","relation":{},"ISSN":["0031-6970","1432-1041"],"issn-type":[{"value":"0031-6970","type":"print"},{"value":"1432-1041","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,23]]}}}