{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T05:31:04Z","timestamp":1759815064690,"version":"3.40.5"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T00:00:00Z","timestamp":1593475200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T00:00:00Z","timestamp":1593475200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Pharmacol"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1007\/s00228-020-02949-2","type":"journal-article","created":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T20:03:18Z","timestamp":1593547398000},"page":"1601-1605","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Adverse drug reactions to anti-diabetic drugs are commonest in patients whose treatment do not adhere to diabetes management clinical guidelines: cross-sectional study in a tertiary care service in sub-Saharan Africa"],"prefix":"10.1007","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0804-5137","authenticated-orcid":false,"given":"Agnes","family":"Elangwe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5631-2810","authenticated-orcid":false,"given":"Jean-Claude","family":"Katte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6483-5758","authenticated-orcid":false,"given":"Donald","family":"Tchapmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2740-2013","authenticated-orcid":false,"given":"Albert","family":"Figueras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9651-8653","authenticated-orcid":false,"given":"Jean Claude","family":"Mbanya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,6,30]]},"reference":[{"issue":"Suppl 2","key":"2949_CR1","doi-asserted-by":"publisher","first-page":"S146","DOI":"10.2337\/dcS15-3003","volume":"39","author":"O Mosenzon","year":"2016","unstructured":"Mosenzon O, Pollack R, Raz I (2016) Treatment of type 2 diabetes: from \u201cguidelines\u201d to \u201cposition statements\u201d and Back: recommendations of the Israel National Diabetes Council. Diabetes Care 39(Suppl 2):S146\u2013S153","journal-title":"Diabetes Care"},{"key":"2949_CR2","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1186\/1472-6920-14-186","volume":"14","author":"MD Corriere","year":"2014","unstructured":"Corriere MD, Minang LB, Sisson SD, Brancati FL, Kalyani RR (2014) The use of clinical guidelines highlights ongoing educational gaps in physicians\u2019 knowledge and decision making related to diabetes. BMC Med Educ 14:186","journal-title":"BMC Med Educ"},{"key":"2949_CR3","doi-asserted-by":"publisher","first-page":"2002","DOI":"10.1056\/NEJMsa1103053","volume":"365","author":"DS Budnitz","year":"2011","unstructured":"Budnitz DS, Lovegrove MC, Shehab N, Richards CL (2011) Emergency hospitalizations for adverse drug events in older Americans. N Engl J Med 365:2002\u20132012","journal-title":"N Engl J Med"},{"key":"2949_CR4","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1038\/clpt.1981.154","volume":"30","author":"CA Naranjo","year":"1981","unstructured":"Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, Janecek E, Domecq C, Greenblatt DJ (1981) A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 30:239\u2013245","journal-title":"Clin Pharmacol Ther"},{"key":"2949_CR5","first-page":"2229","volume":"49","author":"SC Hartwig","year":"1992","unstructured":"Hartwig SC, Siegel J, Schneider PJ (1992) Preventability and severity assessment in reporting adverse drug reactions. Am J Hosp Pharm 49:2229\u20132232","journal-title":"Am J Hosp Pharm"},{"key":"2949_CR6","unstructured":"Cameroon National Diabetes and Hypertension Programme, WDF16-1429. https:\/\/www.worlddiabetesfoundation.org\/projects\/cameroon-wdf16-1429. Accessed 08 January 2020"},{"key":"2949_CR7","doi-asserted-by":"publisher","unstructured":"Nuche-Berenguer B, Kupfer LE (2018) Readiness of Sub-Saharan Africa healthcare systems for the new pandemic, diabetes: a systematic review. J Diabetes Res 9262395. https:\/\/doi.org\/10.1155\/2018\/9262395","DOI":"10.1155\/2018\/9262395"},{"key":"2949_CR8","doi-asserted-by":"publisher","first-page":"2669","DOI":"10.2337\/dci18-0033","volume":"41","author":"MJ Davies","year":"2018","unstructured":"Davies MJ, D\u2019Alessio DA, Fradkin J et al (2018) Management of hyperglycemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 41:2669\u20132701. https:\/\/doi.org\/10.2337\/dci18-0033","journal-title":"Diabetes Care"},{"key":"2949_CR9","unstructured":"NICE (2019) Type 2 diabetes in adults: management. NICE guideline [NG28] Available at: https:\/\/www.nice.org.uk\/guidance\/ng28. Accessed 08 Jan 2020"},{"key":"2949_CR10","doi-asserted-by":"publisher","first-page":"a1051","DOI":"10.4102\/hsag.v24i0.1051","volume":"24","author":"KB Monanabela","year":"2019","unstructured":"Monanabela KB, van Huyssteen M, Coetzee R (2019) Describing medicine therapy management of type 2 diabetes mellitus at primary health care facilities in Cape Town. Health SA 24:a1051. https:\/\/doi.org\/10.4102\/hsag.v24i0.1051","journal-title":"Health SA"},{"key":"2949_CR11","doi-asserted-by":"publisher","first-page":"1118","DOI":"10.1111\/tmi.13137","volume":"23","author":"NNM Soetedjo","year":"2018","unstructured":"Soetedjo NNM, McAllister SM, Ugarte-Gil C et al (2018) Disease characteristics and treatment of patients with diabetes mellitus attending government health services in Indonesia, Peru, Romania and South Africa. Tropical Med Int Health 23:1118\u20131128. https:\/\/doi.org\/10.1111\/tmi.13137","journal-title":"Tropical Med Int Health"},{"key":"2949_CR12","first-page":"247","volume":"145","author":"A Singh","year":"2017","unstructured":"Singh A, Dwivedi S (2017) Study of adverse drug reactions in patients with diabetes attending a tertiary care hospital in New Delhi, India. Indian J Med Res 145:247\u2013249","journal-title":"Indian J Med Res"},{"key":"2949_CR13","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.pcd.2018.06.001","volume":"12","author":"C Torre","year":"2018","unstructured":"Torre C, Guerreiro JP, Romano S, Al\u00e3o S, Concei\u00e7\u00e3o J, Laires P (2018) Real-world prevalence of mild to moderate hypoglycemic episodes in type 2 diabetes in Portugal: results from the HIPOS-PHARMA study. Prim Care Diabetes 12:537\u2013546. https:\/\/doi.org\/10.1016\/j.pcd.2018.06.001","journal-title":"Prim Care Diabetes"},{"key":"2949_CR14","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1016\/S0140-6736(98)07019-6","volume":"352","author":"UKPDS Research Group","year":"1998","unstructured":"UKPDS Research Group (1998) Intensive blood-glucose control with sulfonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes. Lancet 352:837\u2013853","journal-title":"Lancet"},{"key":"2949_CR15","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.diabres.2012.01.002","volume":"96","author":"AJ Green","year":"2012","unstructured":"Green AJ, Fox KM, Grandy S, SHIELD Study Group (2012) Self-reported hypoglycemia and impact on quality of life and depression among adults with type 2 diabetes mellitus. Diabetes Res Clin Pract 96:313\u2013318. https:\/\/doi.org\/10.1016\/j.diabres.2012.01.002","journal-title":"Diabetes Res Clin Pract"},{"key":"2949_CR16","doi-asserted-by":"publisher","first-page":"12992","DOI":"10.1038\/s41598-019-49424-2","volume":"9","author":"T Horii","year":"2019","unstructured":"Horii T, Iwasawa M, Kabeya Y, Atuda K (2019) Polypharmacy and oral antidiabetic treatment for type 2 diabetes characterised by drug class and patient characteristics: a Japanese database analysis. Sci Rep 9:12992. https:\/\/doi.org\/10.1038\/s41598-019-49424-2","journal-title":"Sci Rep"}],"container-title":["European Journal of Clinical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00228-020-02949-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00228-020-02949-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00228-020-02949-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T23:23:26Z","timestamp":1625009006000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00228-020-02949-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,30]]},"references-count":16,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["2949"],"URL":"https:\/\/doi.org\/10.1007\/s00228-020-02949-2","relation":{},"ISSN":["0031-6970","1432-1041"],"issn-type":[{"type":"print","value":"0031-6970"},{"type":"electronic","value":"1432-1041"}],"subject":[],"published":{"date-parts":[[2020,6,30]]},"assertion":[{"value":"27 February 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 June 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}