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This often remains unrecognized and adjustment of drug therapy is lacking. To determine renal function in clinical routine, the CKD-EPI equation is used to calculate an indexed eGFR (ml\/min\/1.73m<jats:sup>2<\/jats:sup>). For drug dosing, it has to be individualized to a non-indexed eGFR (ml\/min) by the patient\u2019s body surface area. Here, we investigated the number of patients admitted to urological wards of a teaching hospital with RI between July and December 2016. Additionally, we correctly used the eGFR<jats:sub>non-indexed<\/jats:sub>for drug and dosage adjustments and to analyse the use of renal risk drugs (RRD) and renal drug-related problems (rDRP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a retrospective observational study, urological patients with pharmacist-led medication reconciliation at hospital admission and eGFR<jats:sub>indexed<\/jats:sub>(CKD-EPI) of 15\u201359\u00a0ml\/min\/1.73m<jats:sup>2<\/jats:sup>were identified. Indexed eGFR (ml\/min\/1.73m<jats:sup>2<\/jats:sup>) was recalculated with body surface area to non-indexed eGFR (ml\/min) for correct drug dosing. Medication at admission was reviewed for RRD and based on the eGFR<jats:sub>non-indexed<\/jats:sub>for rDRP, e.g. inappropriate dose or contraindication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 1320 screened patients, 270 (20.5%) presented with an eGFR<jats:sub>indexed<\/jats:sub>of 15\u201359\u00a0ml\/min\/1.73m<jats:sup>2<\/jats:sup>. After readjustment, 203 (15.4%) patients had an eGFR<jats:sub>non-indexed<\/jats:sub>of 15\u201359\u00a0ml\/min. Of these, 190 (93.6%) used \u2265\u20091 drugs at admission with 660 of 1209 (54.7%) drugs classified as RRD. At least one rDRP was identified in 115 (60.5%) patients concerning 264 (21.8%) drugs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Renal impairment is a common risk factor for medication safety in urologic patients admitted to a hospital. Considerable shifts were seen in eGFR-categories when correctly calculating eGFR<jats:sub>non-indexed<\/jats:sub>for drug dosing purposes. The fact that more than half of the study patients showed rDRP at hospital admission underlines the need to consider this risk factor appropriately.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00228-020-02953-6","type":"journal-article","created":{"date-parts":[[2020,7,10]],"date-time":"2020-07-10T19:02:36Z","timestamp":1594407756000},"page":"1683-1693","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Correct use of non-indexed eGFR for drug dosing and renal drug-related problems at hospital admission"],"prefix":"10.1007","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9630-8661","authenticated-orcid":false,"given":"Sarah","family":"Seiberth","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominik","family":"Bauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf","family":"Sch\u00f6nermarck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna","family":"Mannell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Stief","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joerg","family":"Hasford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2871-0605","authenticated-orcid":false,"given":"Dorothea","family":"Strobach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,10]]},"reference":[{"key":"2953_CR1","unstructured":"Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group (2013) KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. 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