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Each SGA user was matched to 10 population controls on age, sex, and the SGA initiation date. The outcome was incident AKI within 90\u00a0days after the index date. Cox regression was used to estimate hazard ratios (HRs) with 95% confidence intervals (CIs), adjusting for potential confounders.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>In the study, 36,581 new SGA users and 365,810 controls were included. The 90-day incidence rate of AKI was 4.38 and 1.70 per 1000 person-years among SGA users and controls, respectively, corresponding to a crude HR of 2.57 (1.79\u20133.68). The fully adjusted HR (aHR) was 1.43 (0.89\u20132.27) for all SGAs. The risk differed among individual drugs with aHRs for olanzapine 3.50 (1.20\u201310.23), quetiapine 1.62 (0.81\u20133.26), and risperidone 0.68 (0.28\u20131.64). In sensitivity analyses, the aHR declined to 1.24 (0.95\u20131.61) at 1-year follow-up.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Olanzapine use was associated with a significantly increased 90-day AKI risk. For quetiapine, the risk was elevated but not significant, and risperidone had no association. CIs were wide and confounder adjustment largely impacted the estimates. Main limitations included residual confounding and incomplete recording of AKI diagnoses.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00228-022-03339-6","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T14:05:00Z","timestamp":1654005900000},"page":"1341-1349","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Incidence of hospital contacts with acute kidney injury after initiation of second-generation antipsychotics in older adults: a Danish population-based cohort study"],"prefix":"10.1007","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4183-9094","authenticated-orcid":false,"given":"Reeha","family":"Sharon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theis","family":"Lange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mia","family":"Aakj\u00e6r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Br\u00f8gger Kristiansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Baltzer Houlind","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Andersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"issue":"6","key":"3339_CR1","doi-asserted-by":"publisher","first-page":"1382","DOI":"10.1093\/schbul\/sbaa073","volume":"46","author":"JC Badcock","year":"2020","unstructured":"Badcock JC, Lar\u00f8i F, Kamp K, Kelsall-Foreman I, Bucks RS, Weinborn M, Begemann M, Taylor J-P, Collerton D, O\u2019Brien JT, El Haj M, Ffytche D, Sommer IE (2020) Hallucinations in older adults: a practical review. 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