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SES was measured by education, income, and private health insurance. Higher-risk drugs included antithrombotic agents, beta-blockers, calcium channel blockers, diuretics, renin\u2013angiotensin\u2013aldosterone system (RAAS) inhibitors, psychoanaleptics, and NSAIDs. Polypharmacy was categorised as 0\u20134, 5\u20139, and 10\u2009+\u2009drug classes. Multivariable logistic and ordinal regression models adjusted for age, sex, and multimorbidity were used.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The study included 1,401 individuals aged\u2009\u2265\u200970\u00a0years (median age 79; 43% male); 53% had\u2009\u2265\u20093 chronic conditions. 43% had primary\/no education, 46% had below-median income, and 55% lacked private health insurance. Antithrombotics were the most prescribed higher-risk drug (38%), and 41% had 10\u2009+\u2009different drug classes. Higher-risk prescribing and polypharmacy were more prevalent in those with lower SES. Participants with low SES were significantly more likely to be prescribed higher-risk drugs and experience polypharmacy. The greatest association was for psychoanaleptics: adjusted OR 1.97 [95% CI: 1.32;2.95] for primary\/no formal education vs. third-level education, and 1.73 [95% CI: 1.30;2.30] for no vs. private health insurance.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>SES-related disparities in higher-risk prescribing highlight the need for targeted interventions addressing social determinants of health in older populations.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00228-025-03896-6","type":"journal-article","created":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T09:43:45Z","timestamp":1754387025000},"page":"1609-1622","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association between socioeconomic status and dispensing of higher-risk drug classes and polypharmacy in older community-based populations: a nationwide cohort study"],"prefix":"10.1007","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0864-1577","authenticated-orcid":false,"given":"Juliane","family":"Frydenlund","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Cosgrave","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Moriarty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma","family":"Wallace","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ciara","family":"Kirke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caitriona","family":"Cahir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,8,5]]},"reference":[{"issue":"5","key":"3896_CR1","doi-asserted-by":"publisher","first-page":"481","DOI":"10.7861\/clinmedicine.16-5-481","volume":"16","author":"JJ Coleman","year":"2016","unstructured":"Coleman JJ, Pontefract SK (2016) Adverse drug reactions. 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