{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:46:37Z","timestamp":1792176397743,"version":"4.4.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T00:00:00Z","timestamp":1601078400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T00:00:00Z","timestamp":1601078400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01HD096800"],"award-info":[{"award-number":["R01HD096800"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005393","name":"American Roentgen Ray Society","doi-asserted-by":"publisher","award":["ARRS Scholar 2018"],"award-info":[{"award-number":["ARRS Scholar 2018"]}],"id":[{"id":"10.13039\/100005393","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006098","name":"Radiological Society of North America","doi-asserted-by":"publisher","award":["Seed Grant"],"award-info":[{"award-number":["Seed Grant"]}],"id":[{"id":"10.13039\/100006098","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuroradiology"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1007\/s00234-020-02552-3","type":"journal-article","created":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T01:02:17Z","timestamp":1601082137000},"page":"585-591","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Resting state functional MRI in infants with prenatal opioid exposure\u2014a pilot study"],"prefix":"10.1007","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5224-1891","authenticated-orcid":false,"given":"Rupa","family":"Radhakrishnan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nahla M. H.","family":"Elsaid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Senthilkumar","family":"Sadhasivam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas A.","family":"Reher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbey C.","family":"Hines","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karmen K.","family":"Yoder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Saykin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Chien","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,9,26]]},"reference":[{"issue":"5","key":"2552_CR1","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1097\/AOG.0000000000000208","volume":"123","author":"RJ Desai","year":"2014","unstructured":"Desai RJ, Hernandez-Diaz S, Bateman BT, Huybrechts KF (2014) Increase in prescription opioid use during pregnancy among Medicaid-enrolled women. Obstet Gynecol 123(5):997\u20131002","journal-title":"Obstet Gynecol"},{"issue":"8","key":"2552_CR2","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1038\/jp.2015.36","volume":"35","author":"SW Patrick","year":"2015","unstructured":"Patrick SW, Davis MM, Lehmann CU, Cooper WO (2015) Increasing incidence and geographic distribution of neonatal abstinence syndrome: United States 2009 to 2012. J Perinatol 35(8):650\u2013655","journal-title":"J Perinatol"},{"issue":"18","key":"2552_CR3","doi-asserted-by":"publisher","first-page":"1934","DOI":"10.1001\/jama.2012.3951","volume":"307","author":"SW Patrick","year":"2012","unstructured":"Patrick SW et al (2012) Neonatal abstinence syndrome and associated health care expenditures: United States, 2000-2009. JAMA 307(18):1934\u20131940","journal-title":"JAMA"},{"issue":"1","key":"2552_CR4","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1038\/npp.2014.147","volume":"40","author":"EJ Ross","year":"2015","unstructured":"Ross EJ, Graham DL, Money KM, Stanwood GD (2015) Developmental consequences of fetal exposure to drugs: what we know and what we still must learn. Neuropsychopharmacology 40(1):61\u201387","journal-title":"Neuropsychopharmacology"},{"key":"2552_CR5","doi-asserted-by":"publisher","unstructured":"Romanowicz M, Vande Voort JL, Shekunov J, Oesterle TS, Thusius NJ, Rummans TA, Croarkin PE, Karpyak VM, Lynch BA, Schak KM (2019) The effects of parental opioid use on the parent-child relationship and children\u2019s developmental and behavioral outcomes: a systematic review of published reports. Child Adolesc Psychiatry Ment Health 13:5. https:\/\/doi.org\/10.1186\/s13034-019-0266-3","DOI":"10.1186\/s13034-019-0266-3"},{"key":"2552_CR6","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.ntt.2018.04.004","volume":"68","author":"E Nygaard","year":"2018","unstructured":"Nygaard E, Slinning K, Moe V, Due-T\u00f8nnessen P, Fjell A, Walhovd KB (2018) Neuroanatomical characteristics of youths with prenatal opioid and poly-drug exposure. Neurotoxicol Teratol 68:13\u201326","journal-title":"Neurotoxicol Teratol"},{"issue":"3","key":"2552_CR7","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1001\/jama.1992.03480030084043","volume":"267","author":"LC Mayes","year":"1992","unstructured":"Mayes LC, Granger RH, Bornstein MH, Zuckerman B (1992) The problem of prenatal cocaine exposure. A rush to judgment. JAMA 267(3):406\u2013408","journal-title":"JAMA"},{"issue":"4","key":"2552_CR8","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1164\/rccm.200211-1357OC","volume":"169","author":"MN Upton","year":"2004","unstructured":"Upton MN, Smith GD, McConnachie A, Hart CL, Watt GCM (2004) Maternal and personal cigarette smoking synergize to increase airflow limitation in adults. Am J Respir Crit Care Med 169(4):479\u2013487","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"2552_CR9","doi-asserted-by":"publisher","first-page":"e842","DOI":"10.1542\/peds.2008-2084","volume":"123","author":"LR Stroud","year":"2009","unstructured":"Stroud LR, Paster RL, Goodwin MS, Shenassa E, Buka S, Niaura R, Rosenblith JF, Lipsitt LP (2009) Maternal smoking during pregnancy and neonatal behavior: a large-scale community study. Pediatrics 123(5):e842\u2013e848","journal-title":"Pediatrics"},{"issue":"24","key":"2552_CR10","doi-asserted-by":"publisher","first-page":"10098","DOI":"10.1523\/JNEUROSCI.5004-12.2013","volume":"33","author":"S Treit","year":"2013","unstructured":"Treit S, Lebel C, Baugh L, Rasmussen C, Andrew G, Beaulieu C (2013) Longitudinal MRI reveals altered trajectory of brain development during childhood and adolescence in fetal alcohol spectrum disorders. J Neurosci 33(24):10098\u201310109","journal-title":"J Neurosci"},{"key":"2552_CR11","doi-asserted-by":"publisher","first-page":"601","DOI":"10.3389\/fnhum.2015.00601","volume":"9","author":"K Grewen","year":"2015","unstructured":"Grewen K, Salzwedel AP, Gao W (2015) Functional connectivity disruption in neonates with prenatal marijuana exposure. Front Hum Neurosci 9:601","journal-title":"Front Hum Neurosci"},{"issue":"14","key":"2552_CR12","doi-asserted-by":"publisher","first-page":"5860","DOI":"10.1523\/JNEUROSCI.4333-14.2015","volume":"35","author":"AP Salzwedel","year":"2015","unstructured":"Salzwedel AP, Grewen KM, Vachet C, Gerig G, Lin W, Gao W (2015) Prenatal drug exposure affects neonatal brain functional connectivity. J Neurosci 35(14):5860\u20135869","journal-title":"J Neurosci"},{"issue":"1","key":"2552_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.pediatrneurol.2012.04.008","volume":"47","author":"KB Walhovd","year":"2012","unstructured":"Walhovd KB, Watts R, Amlien I, Woodward LJ (2012) Neural tract development of infants born to methadone-maintained mothers. Pediatr Neurol 47(1):1\u20136","journal-title":"Pediatr Neurol"},{"issue":"12","key":"2552_CR14","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1038\/jp.2014.111","volume":"34","author":"Q Yuan","year":"2014","unstructured":"Yuan Q et al (2014) Do maternal opioids reduce neonatal regional brain volumes? A pilot study. J Perinatol 34(12):909\u2013913","journal-title":"J Perinatol"},{"issue":"8","key":"2552_CR15","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1038\/jp.2015.22","volume":"35","author":"JB Bier","year":"2015","unstructured":"Bier JB, Finger AS, Bier BA, Johnson TA, Coyle MG (2015) Growth and developmental outcome of infants with in-utero exposure to methadone vs buprenorphine. J Perinatol 35(8):656\u2013659","journal-title":"J Perinatol"},{"issue":"2","key":"2552_CR16","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1016\/j.neuroimage.2011.09.015","volume":"62","author":"M Jenkinson","year":"2012","unstructured":"Jenkinson M, Beckmann CF, Behrens TEJ, Woolrich MW, Smith SM (2012) Fsl. Neuroimage 62(2):782\u2013790","journal-title":"Neuroimage"},{"issue":"3","key":"2552_CR17","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1002\/hbm.10062","volume":"17","author":"SM Smith","year":"2002","unstructured":"Smith SM (2002) Fast robust automated brain extraction. Hum Brain Mapp 17(3):143\u2013155","journal-title":"Hum Brain Mapp"},{"key":"2552_CR18","first-page":"13","volume":"4","author":"Y Chao-Gan","year":"2010","unstructured":"Chao-Gan Y, Yu-Feng Z (2010) DPARSF: a MATLAB toolbox for \u201cpipeline\u201d data analysis of resting-state fMRI. Front Syst Neurosci 4:13","journal-title":"Front Syst Neurosci"},{"key":"2552_CR19","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1016\/S1053-8119(03)00336-7","volume":"20","author":"J Andersson","year":"2003","unstructured":"Andersson J, Skare S (2003) How to correct susceptibility distortions in spin-echo echo-planar images: application to diffusion tensor imaging. NeuroImage 20:870\u2013888","journal-title":"NeuroImage"},{"key":"2552_CR20","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1006\/nimg.2002.1132","volume":"17","author":"M Jenkinson","year":"2002","unstructured":"Jenkinson M, Bannister P, Brady M, Smith S (2002) Improved optimization for the robust and accurate linear registration and motion correction of brain images. NeuroImage 17:825\u2013841","journal-title":"NeuroImage"},{"issue":"3","key":"2552_CR21","doi-asserted-by":"publisher","first-page":"2142","DOI":"10.1016\/j.neuroimage.2011.10.018","volume":"59","author":"JD Power","year":"2012","unstructured":"Power JD, Barnes KA, Snyder AZ, Schlaggar BL, Petersen SE (2012) Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage 59(3):2142\u20132154","journal-title":"Neuroimage"},{"issue":"4","key":"2552_CR22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0018746","volume":"6","author":"F Shi","year":"2011","unstructured":"Shi F, Yap PT, Wu G, Jia H, Gilmore JH, Lin W, Shen D (2011) Infant brain atlases from neonates to 1- and 2-year-olds. PLoS One 6(4):e18746","journal-title":"PLoS One"},{"key":"2552_CR23","doi-asserted-by":"publisher","first-page":"2033","DOI":"10.1016\/j.neuroimage.2010.09.025","volume":"54","author":"B Avants","year":"2011","unstructured":"Avants B et al (2011) A reproducible evaluation of ANTs similarity metric performance in brain image registration. Neuroimage 54:2033\u20132044","journal-title":"Neuroimage"},{"issue":"4","key":"2552_CR24","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1002\/mrm.1910340409","volume":"34","author":"B Biswal","year":"1995","unstructured":"Biswal B, Zerrin Yetkin F, Haughton VM, Hyde JS (1995) Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 34(4):537\u2013541","journal-title":"Magn Reson Med"},{"issue":"9","key":"2552_CR25","doi-asserted-by":"publisher","first-page":"1727","DOI":"10.1016\/j.pain.2014.05.023","volume":"155","author":"LE Simons","year":"2014","unstructured":"Simons LE, Pielech M, Erpelding N, Linnman C, Moulton E, Sava S, Lebel A, Serrano P, Sethna N, Berde C, Becerra L, Borsook D (2014) The responsive amygdala: treatment-induced alterations in functional connectivity in pediatric complex regional pain syndrome. Pain 155(9):1727\u20131742","journal-title":"Pain"},{"issue":"8","key":"2552_CR26","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.1162\/jocn_a_00392","volume":"25","author":"M Sakaki","year":"2013","unstructured":"Sakaki M, Nga L, Mather M (2013) Amygdala functional connectivity with medial prefrontal cortex at rest predicts the positivity effect in older adults' memory. J Cogn Neurosci 25(8):1206\u20131224","journal-title":"J Cogn Neurosci"},{"issue":"5","key":"2552_CR27","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1080\/09297049.2014.967201","volume":"21","author":"C Konijnenberg","year":"2015","unstructured":"Konijnenberg C, Melinder A (2015) Executive function in preschool children prenatally exposed to methadone or buprenorphine. Child Neuropsychol 21(5):570\u2013585","journal-title":"Child Neuropsychol"},{"key":"2552_CR28","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.ntt.2015.02.002","volume":"48","author":"JB Schweitzer","year":"2015","unstructured":"Schweitzer JB, Riggins T, Liang X, Gallen C, Kurup PK, Ross TJ, Black MM, Nair P, Salmeron BJ (2015) Prenatal drug exposure to illicit drugs alters working memory-related brain activity and underlying network properties in adolescence. Neurotoxicol Teratol 48:69\u201377","journal-title":"Neurotoxicol Teratol"},{"issue":"2","key":"2552_CR29","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.biopsych.2018.06.023","volume":"85","author":"AM Graham","year":"2019","unstructured":"Graham AM, Rasmussen JM, Entringer S, Ben Ward E, Rudolph MD, Gilmore JH, Styner M, Wadhwa PD, Fair DA, Buss C (2019) Maternal cortisol concentrations during pregnancy and sex-specific associations with neonatal amygdala connectivity and emerging internalizing behaviors. Biol Psychiatry 85(2):172\u2013181","journal-title":"Biol Psychiatry"},{"issue":"2","key":"2552_CR30","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.biopsych.2017.05.027","volume":"83","author":"AM Graham","year":"2018","unstructured":"Graham AM, Rasmussen JM, Rudolph MD, Heim CM, Gilmore JH, Styner M, Potkin SG, Entringer S, Wadhwa PD, Fair DA, Buss C (2018) Maternal systemic interleukin-6 during pregnancy is associated with newborn amygdala phenotypes and subsequent behavior at 2 years of age. Biol Psychiatry 83(2):109\u2013119","journal-title":"Biol Psychiatry"},{"key":"2552_CR31","doi-asserted-by":"crossref","unstructured":"Rotem-Kohavi N et al (2019) Hub distribution of the brain functional networks of newborns prenatally exposed to maternal depression and SSRI antidepressants. Depress Anxiety","DOI":"10.1002\/da.22906"}],"container-title":["Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00234-020-02552-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00234-020-02552-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00234-020-02552-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,25]],"date-time":"2021-09-25T23:12:27Z","timestamp":1632611547000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00234-020-02552-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,26]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["2552"],"URL":"https:\/\/doi.org\/10.1007\/s00234-020-02552-3","relation":{},"ISSN":["0028-3940","1432-1920"],"issn-type":[{"value":"0028-3940","type":"print"},{"value":"1432-1920","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,26]]},"assertion":[{"value":"28 May 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 September 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in the studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study. For minor participants, informed consent was obtained from the guardian.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}