{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:20:26Z","timestamp":1771474826223,"version":"3.50.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T00:00:00Z","timestamp":1636675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T00:00:00Z","timestamp":1636675200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuroradiology"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1007\/s00234-021-02848-y","type":"journal-article","created":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T02:02:18Z","timestamp":1636682538000},"page":"1127-1134","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Association between carotid artery dissection and vascular tortuosity: a case\u2013control study"],"prefix":"10.1007","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1199-7312","authenticated-orcid":false,"given":"Gabriele","family":"Venturini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luisa","family":"Vuolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Pracucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Picchioni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ylenia","family":"Failli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Benvenuti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8409-4782","authenticated-orcid":false,"given":"Cristina","family":"Sarti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,11,12]]},"reference":[{"key":"2848_CR1","doi-asserted-by":"publisher","first-page":"1809","DOI":"10.1212\/01.wnl.0000244486.30455.71","volume":"67","author":"VH Lee","year":"2006","unstructured":"Lee VH, Brown RD, Jayawant NM et al (2006) Incidence and outcome of cervical artery dissection: a population-based study. Neurology 67:1809\u20131812","journal-title":"Neurology"},{"key":"2848_CR2","doi-asserted-by":"publisher","first-page":"157","DOI":"10.2147\/VHRM.S53203","volume":"11","author":"D Smajlovic","year":"2015","unstructured":"Smajlovic D (2015) Strokes in young adults: epidemiology and prevention. Vasc Health Risk Manag 11:157\u2013164","journal-title":"Vasc Health Risk Manag"},{"key":"2848_CR3","doi-asserted-by":"crossref","unstructured":"Blum CA, Yaghi S (2015) Cervical artery dissection: a review of epidemiology, pathophysiology, treatment and outcome. Arch Neurosci 2(4)","DOI":"10.5812\/archneurosci.26670"},{"key":"2848_CR4","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1097\/WCO.0000000000000056","volume":"27","author":"S Debette","year":"2014","unstructured":"Debette S (2014) Pathophysiology of cervical artery dissection: what have we learnt from large hospital-based cohorts? Curr Opin Neurol 27:20\u201328","journal-title":"Curr Opin Neurol"},{"key":"2848_CR5","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/j.mehy.2003.10.006","volume":"62","author":"DC Lelong","year":"2004","unstructured":"Lelong DC, Logak M (2004) Pathogenesis of spontaneous cervico-cerebral artery dissection. A hypothesis and a review of literature. Med Hypothesis 62:453\u2013457","journal-title":"Med Hypothesis"},{"key":"2848_CR6","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1001\/archneur.56.7.851","volume":"56","author":"AJ Grau","year":"1999","unstructured":"Grau AJ, Brandt T, Buggle F et al (1999) Association of cervical artery dissection with recent infection. Arch Neurol 56:851\u2013856","journal-title":"Arch Neurol"},{"key":"2848_CR7","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1161\/hs0302.103625","volume":"33","author":"A Pezzini","year":"2002","unstructured":"Pezzini A, Del Zotto E, Archetti S et al (2002) Plasma homocysteine concentration, c677t mthf genotype and 844ins68bp cbs genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke. Stroke 33:664\u2013669","journal-title":"Stroke"},{"key":"2848_CR8","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1212\/WNL.0b013e31822f03fc","volume":"77","author":"S Debette","year":"2011","unstructured":"Debette S, Grond-Ginsbach C, Bodenant M et al (2011) Differential features of carotid and vertebral artery dissection: the CADISP study. Neurology 77:1174\u20131181","journal-title":"Neurology"},{"key":"2848_CR9","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/s11910-017-0769-3","volume":"17","author":"ST Engelter","year":"2017","unstructured":"Engelter ST, Traenka C, Lyrer P (2017) Dissection of cervical and cerebral arteries. Curr Neurol Neurosci Rep 17:59\u201369","journal-title":"Curr Neurol Neurosci Rep"},{"key":"2848_CR10","first-page":"459","volume":"40","author":"S Debette","year":"2009","unstructured":"Debette S, Hugh SM (2009) The genetics of cervical artery dissection: a systematic review. Stroke 40:459\u2013466","journal-title":"Stroke"},{"key":"2848_CR11","doi-asserted-by":"publisher","first-page":"2023","DOI":"10.1212\/WNL.0000000000001027","volume":"83","author":"S Debette","year":"2014","unstructured":"Debette S, Goeggel Simonetti B, Schilling S et al (2014) Familial occurrence and heritable connective tissue disorders in cervical artery dissection. Neurology 83:2023\u20132031","journal-title":"Neurology"},{"key":"2848_CR12","doi-asserted-by":"publisher","first-page":"2548","DOI":"10.1161\/STROKEAHA.116.013736","volume":"47","author":"K Bum Yoon","year":"2016","unstructured":"Bum Yoon K, Ewha Y, Na-Young K et al (2016) Vascular tortuosity may be associated with cervical artery dissection. Stroke 47:2548\u20132552","journal-title":"Stroke"},{"key":"2848_CR13","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1007\/s00234-014-1436-x","volume":"57","author":"L Saba","year":"2015","unstructured":"Saba L, Argiolas GM, Sumer S et al (2015) Association between internal carotid artery dissection and arterial tortuosity. Neuroradiology 57:149\u2013153","journal-title":"Neuroradiology"},{"key":"2848_CR14","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1007\/s00234-017-1836-9","volume":"59","author":"A Giossi","year":"2017","unstructured":"Giossi A, Mardighian D, Caria F et al (2017) Arterial tortuosity in patients with spontaneous cervical artery dissection. Neuroradiology 59:571\u2013575","journal-title":"Neuroradiology"},{"key":"2848_CR15","doi-asserted-by":"publisher","first-page":"2120","DOI":"10.1212\/01.wnl.0000264892.92538.a9","volume":"68","author":"R Dittrich","year":"2007","unstructured":"Dittrich R, Heidbreder A, Rohsbach D et al (2007) Connective tissue and vascular phenotype in patients with cervical artery dissection. Neurology 68:2120\u20132124","journal-title":"Neurology"},{"key":"2848_CR16","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1212\/WNL.15.1.7","volume":"15","author":"J Weibel","year":"1965","unstructured":"Weibel J, Fields WS (1965) Tortuosity, coiling, and kinking of the ICA. Etiology and radiographic anatomy. Neurology 15:7\u201311","journal-title":"Neurology"},{"key":"2848_CR17","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/S0140-6736(61)90004-6","volume":"25","author":"H Metz","year":"1961","unstructured":"Metz H, Murray-Leslie RM, Bannister RG et al (1961) Kinking of the ICA in relation to cerebrovascular disease. Lancet 25:424\u2013426","journal-title":"Lancet"},{"key":"2848_CR18","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1161\/STROKEAHA.113.001057","volume":"44","author":"M Von Babo","year":"2013","unstructured":"Von Babo M, De Marchis GM, Sarikaya H et al (2013) Differences and similarities between spontaneous dissections of the internal carotid artery and the vertebral artery. Stroke 44:1537\u20131542","journal-title":"Stroke"},{"key":"2848_CR19","first-page":"205","volume":"32","author":"DH Padget","year":"1948","unstructured":"Padget DH (1948) The development of the cranial arteries in the human embryo. Contrib Embryol 32:205","journal-title":"Contrib Embryol"},{"key":"2848_CR20","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1002\/ar.1091110207","volume":"111","author":"A Barry","year":"1951","unstructured":"Barry A (1951) The aortic arch derivatives in the human adult. Anar Rec 111:221","journal-title":"Anar Rec"},{"issue":"4","key":"2848_CR21","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1016\/j.ejvs.2020.11.046","volume":"61","author":"Z Lijuan","year":"2021","unstructured":"Lijuan Z, Xiaoshuang L, Beibei G et al (2021) Increased internal carotid artery tortuosity is a risk factor for spontaneous cervicocerebral artery dissection. Eur J Endovasc Surg 61(4):542\u2013549","journal-title":"Eur J Endovasc Surg"},{"issue":"4","key":"2848_CR22","first-page":"413","volume":"62","author":"TK Sarasa","year":"2018","unstructured":"Sarasa TK, Waleed B, Vance TL et al (2018) Association between carotid artery tortuosity and carotid dissection: a case-control study. J Neurosurg Sci 62(4):413\u2013417","journal-title":"J Neurosurg Sci"},{"issue":"10","key":"2848_CR23","first-page":"1738","volume":"40","author":"JP Welby","year":"2019","unstructured":"Welby JP, Kim ST, Carr CM et al (2019) Carotid artery tortuosity is associated with connective tissue diseases. AJNR Am J Neuroradiol 40(10):1738\u20131743","journal-title":"AJNR Am J Neuroradiol"}],"container-title":["Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00234-021-02848-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00234-021-02848-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00234-021-02848-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T03:37:50Z","timestamp":1652931470000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00234-021-02848-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,12]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["2848"],"URL":"https:\/\/doi.org\/10.1007\/s00234-021-02848-y","relation":{},"ISSN":["0028-3940","1432-1920"],"issn-type":[{"value":"0028-3940","type":"print"},{"value":"1432-1920","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,12]]},"assertion":[{"value":"26 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 October 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 November 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"All procedures performed in the studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}