{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T09:45:04Z","timestamp":1788515104643,"version":"build-2803163510"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T00:00:00Z","timestamp":1758499200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T00:00:00Z","timestamp":1758499200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100006775","name":"GE HealthCare","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100006775","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuroradiology"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Traumatic vertebral fractures present a significant diagnostic challenge in emergency settings. Magnetic resonance imaging (MRI) excels in detecting bone marrow edema but faces practical limitations in acute trauma care. This prospective study evaluates the diagnostic accuracy of Dual-Energy Computed Tomography (DECT) in detecting traumatic vertebral bone marrow edema within a Level I trauma center environment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Between May 2020 and July 2023, 291 DECT examinations were performed on adult patients presenting with suspected or confirmed spinal injury. From these, 233 (80.1%) met quality criteria for analysis. A subgroup of 47 patients underwent additional MRI as reference standard, with 44 (93.6%) providing diagnostically evaluable images. Two board-certified radiologists independently assessed vertebral bone marrow edema presence in blinded, randomized evaluations using both modalities. Diagnostic parameters, examination times, radiation exposure, and cost-efficiency were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>DECT demonstrated an overall sensitivity of 82.9% and specificity of 96.6% for detecting vertebral bone marrow edema compared to MRI. The thoracolumbar junction showed highest sensitivity (91.7% for L3). DECT examination time was 7.2 minutes (including post-processing) versus 12 minutes for MRI, meaning MRI required 66.7% more time than DECT. DECT radiation exposure showed a mean dose-length product increase of only 3% compared to conventional CT. Body mass index showed no significant influence on DECT interpretability (p=0.196) or diagnostic accuracy except in isolated segments (L3, T11). Cost-benefit analysis revealed potential savings of 49.1% (\u20ac104.40) per spinal segment with DECT-based diagnostic pathways.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>DECT offers high diagnostic accuracy for detecting traumatic vertebral bone marrow edema with substantial time and cost advantages compared to MRI. The technique demonstrates particular value in acute trauma settings, while acknowledging limitations from artifacts (19.9% of cases) primarily caused by medical devices. These findings support implementing DECT as an efficient alternative to MRI in spinal trauma diagnostics.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00234-025-03763-2","type":"journal-article","created":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T05:36:45Z","timestamp":1758519405000},"page":"2977-2987","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Diagnostic accuracy of Dual-Energy CT in detecting traumatic vertebral bone marrow edema: a prospective comparative study with MRI in the context of a level I trauma center"],"prefix":"10.1007","volume":"67","author":[{"given":"Thomas","family":"Beyer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Volmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Gahr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc-Andr\u00e9","family":"Weber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,9,22]]},"reference":[{"key":"3763_CR1","doi-asserted-by":"publisher","first-page":"2179","DOI":"10.1007\/s11999-010-1766-x","volume":"469","author":"AJ Burghardt","year":"2011","unstructured":"Burghardt AJ, Link TM, Majumdar S (2011) High-resolution computed tomography for clinical imaging of bone microarchitecture. 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The study was approved by the local ethics committee (institution name and approval number blinded for review).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Research involving human participants"}},{"value":"The Ethics Committee waived the requirement for written informed consent because this retrospective imaging study analysed fully anonymised data obtained during routine clinical care.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"This study was supported by a research grant from GE Healthcare.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}