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We systematically reviewed evidence on patient-centered outcomes, including effects by follow-up time, intervention type, and clinical severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PubMed, EMBASE, and Web of Science were searched (2000\u20132024; updated July 2025). Prospective and retrospective studies of adults with aSAH receiving endovascular treatment for symptomatic vasospasm\/DCI were included. Data extraction followed a PICO framework, and quality was assessed using the Newcastle\u2013Ottawa Scale. Due to inconsistent reporting of angiographic resolution and DCI-related infarction, quantitative synthesis focused on dichotomized favorable functional outcome. Single-arm proportions were pooled using random-effects generalized linear mixed models with prespecified subgroup analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty-nine studies (1,627 patients) were included; 38 contributed to pooled analysis. The proportion of favorable functional outcome was 0.55 (95% CI 0.50\u20130.61), with substantial heterogeneity (I\u00b2 \u2248 71%). Subgroup analyses by follow-up duration, intervention modality, and baseline severity showed no significant differences. The two randomized trials reported conflicting results and had limited follow-up. Safety reporting varied but was generally acceptable for pharmacologic spasmolysis; some series suggested higher complication rates with mechanical interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Approximately half of patients treated with endovascular rescue for symptomatic vasospasm\/DCI achieve a favorable functional outcome. However, marked heterogeneity and predominantly observational evidence limit conclusions regarding effectiveness. Standardized, adequately powered randomized trials are needed to clarify the role of endovascular rescue after aSAH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00234-026-03986-x","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T11:33:19Z","timestamp":1774956799000},"page":"1103-1116","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Endovascular treatment of symptomatic vasospasm and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage \u2013 a systematic review and meta-analysis"],"prefix":"10.1007","volume":"68","author":[{"given":"Michael","family":"Veldeman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Rossmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roel","family":"Haeren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Schenck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Raj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte S.","family":"Weyland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,31]]},"reference":[{"issue":"10355","key":"3986_CR1","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1016\/s0140-6736(22)00938-2","volume":"400","author":"J Claassen","year":"2022","unstructured":"Claassen J, Park S (2022) Spontaneous subarachnoid haemorrhage. 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