{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:17:14Z","timestamp":1786979834771,"version":"build-2736575974"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T00:00:00Z","timestamp":1783296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T00:00:00Z","timestamp":1783296000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005743","name":"Universit\u00e0 Cattolica del Sacro Cuore","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005743","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuroradiology"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anatomical variants of the anterior cerebral artery (ACA) may increase technical complexity during endovascular treatment of distal ACA aneurysms (DACA). However, their impact on treatment outcomes remains unclear. This study evaluated whether ACA variants influence angiographic and clinical outcomes following endovascular treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective multicenter analysis was conducted using data from the CRETA Registry, including patients with ruptured and unruptured DACA treated endovascularly. Patients were grouped according to ACA anatomy (variant vs. conventional). Outcomes were compared after propensity score matching (PSM) to adjust for confounders including age, aneurysm rupture status, dome-to-neck ratio, branch origin, and treatment type. The primary outcome was aneurysm occlusion at last follow-up based on the Raymond\u2013Roy classification. Secondary outcomes included ischemic and hemorrhagic complications, vasospasm, and clinical outcome measured by the modified Rankin Scale (mRS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After PSM, 128 patients were included (64 per group). Among patients with available imaging follow-up (54 in the conventional group and 55 in the variant group), adequate occlusion rates were comparable between the variant and conventional ACA groups (81.5% vs. 85.5%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.600). No significant differences were observed in ischemic or hemorrhagic complications, vasospasm, or long-term clinical outcomes. Sensitivity analyses confirmed the robustness of the findings.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ACA anatomical variants do not adversely affect the safety or efficacy of endovascular treatment for DACA. With appropriate anatomical assessment and treatment selection, endovascular therapy remains effective even in the presence of complex ACA configurations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00234-026-04080-y","type":"journal-article","created":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T06:28:29Z","timestamp":1783319309000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Anterior cerebral artery variants and their influence on endovascular outcomes: a propensity score matched analysis from the CRETA registry"],"prefix":"10.1007","author":[{"given":"Arturo","family":"Consoli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Tortora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Claren\u00e7on","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam A.","family":"Dmytriw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eimad","family":"Shotar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Jabbour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marios","family":"Psychogios","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Sporns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajit S.","family":"Puri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ameer E","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oktay","family":"Algin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus A.","family":"M\u00f6hlenbruch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oded","family":"Goren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregoire","family":"Boulouis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Morimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raoul","family":"Pop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna WK","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Pujol Lereis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giancarlo","family":"Salsano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Sgreccia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eytan","family":"Raz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Burel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khawaja Muhammad","family":"Baqir Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riitta","family":"Rautio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Ruggiero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerio","family":"Da Ros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph Domenico","family":"Gabrieli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Levitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Armando","family":"Caragliano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Cognard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaultier","family":"Marnat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Limbucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariangela","family":"Piano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Guedon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Romi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fortunato","family":"Di Caterino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vyval","family":"Mykola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oc\u00edlio","family":"Ribeiro Gon\u00e7alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrien","family":"Guenego","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad","family":"Abdalkader","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanh","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitor M.","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erwah","family":"Kalsoum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldobrando","family":"Broccolini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Pedicelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Scarcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea M.","family":"Alexandre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,6]]},"reference":[{"issue":"7","key":"4080_CR1","doi-asserted-by":"publisher","first-page":"E314","DOI":"10.1161\/STR.0000000000000436","volume":"54","author":"BL Hoh","year":"2023","unstructured":"Hoh BL, Ko NU, Amin-Hanjani S, Hsiang-Yi Chou S, Cruz-Flores S, Dangayach NS et al (2023) Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage: A Guideline From the American Heart Association\/American Stroke Association. Stroke 54(7):E314\u2013E370","journal-title":"Stroke"},{"issue":"8","key":"4080_CR2","doi-asserted-by":"publisher","first-page":"2368","DOI":"10.1161\/STR.0000000000000070","volume":"46","author":"BG Thompson","year":"2015","unstructured":"Thompson BG, Brown RD, Amin-Hanjani S, Broderick JP, Cockroft KM, Connolly ES et al (2015) Guidelines for the Management of Patients With Unruptured Intracranial Aneurysms: A Guideline for Healthcare Professionals From the American Heart Association\/American Stroke Association. Stroke 46(8):2368\u20132400","journal-title":"Stroke"},{"issue":"7","key":"4080_CR3","doi-asserted-by":"publisher","first-page":"2046","DOI":"10.1161\/STROKEAHA.113.000733","volume":"44","author":"L Pierot","year":"2013","unstructured":"Pierot L, Wakhloo AK (2013) Endovascular treatment of intracranial aneurysms: Current status. Stroke 44(7):2046\u20132054","journal-title":"Stroke"},{"issue":"3","key":"4080_CR4","doi-asserted-by":"publisher","first-page":"E477","DOI":"10.1093\/neuros\/nyz038","volume":"85","author":"E Atallah","year":"2019","unstructured":"Atallah E, Saad H, Mouchtouris N, Bekelis K, Walker J, Chalouhi N et al (2019) Pipeline for distal cerebral circulation aneurysms. Clin Neurosurg 85(3):E477\u2013E484","journal-title":"Clin Neurosurg"},{"issue":"6","key":"4080_CR5","doi-asserted-by":"publisher","first-page":"708","DOI":"10.1177\/15910199211063703","volume":"28","author":"C Ma","year":"2022","unstructured":"Ma C, Zhu H, Liang S, Liang F, Han J, Jia Z et al (2022) Pipeline for the treatment of distal cerebral circulation aneurysms: A multicenter study focusing on periprocedural Complications. Interventional Neuroradiol 28(6):708\u2013718","journal-title":"Interventional Neuroradiol"},{"issue":"12","key":"4080_CR6","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1136\/jnis-2024-022315","volume":"17","author":"L Scarcia","year":"2024","unstructured":"Scarcia L, Claren\u00e7on F, Dmytriw AA, Shotar E, Premat K, Jabbour P et al (2024) Flow-diverting stents for the treatment of unruptured distal anterior cerebral artery aneurysms: analysis of the CRETA Registry. J Neurointerv Surg 17(12):1270\u20131276. https:\/\/doi.org\/10.1136\/jnis-2024-022315","journal-title":"J Neurointerv Surg"},{"key":"4080_CR7","volume-title":"Surgical Neuroangiography. Volume 1: Functional Anatomy of Craniofacial Arteries","author":"PBA Lasjaunias","year":"2001","unstructured":"Lasjaunias PBA, ter BKG (2001) Surgical Neuroangiography. Volume 1: Functional Anatomy of Craniofacial Arteries, vol 1, 2nd edn. Springer, Berlin","edition":"2"},{"key":"4080_CR8","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1136\/neurintsurg-2014-011258","volume":"7","author":"JR Mascitelli","year":"2015","unstructured":"Mascitelli JR, Moyle H, Oermann EK, Polykarpou MF, Patel AA, Doshi AH et al (2015) An update to the Raymond\u2013Roy Occlusion Classification of intracranial aneurysms treated with coil embolization. J Neurointerv Surg 7:496\u2013502","journal-title":"J Neurointerv Surg"},{"issue":"1","key":"4080_CR9","doi-asserted-by":"publisher","first-page":"66","DOI":"10.3174\/ajnr.A8926","volume":"47","author":"M Vilardo","year":"2025","unstructured":"Vilardo M, G\u00fcnkan A, Dmytriw AA, Elek A, Scarramal JPL, Bocanegra-Becerra JE et al (2025) Efficacy and Safety of Flow Diversion for Distal Anterior Cerebral Aneurysms: A Systematic Review and Proportional Meta-Analysis. Am J Neuroradiol 47(1):66\u201372. https:\/\/doi.org\/10.3174\/ajnr.A8926","journal-title":"Am J Neuroradiol"},{"issue":"1","key":"4080_CR10","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1136\/neurintsurg-2020-015980","volume":"13","author":"F Cagnazzo","year":"2021","unstructured":"Cagnazzo F, Fanti A, Lefevre PH, Derraz I, Dargazanli C, Gascou G et al (2021) Distal anterior cerebral artery aneurysms treated with flow diversion: experience of a large-volume center and systematic review of the literature. J Neurointerv Surg 13(1):42\u201348","journal-title":"J Neurointerv Surg"},{"issue":"4","key":"4080_CR11","doi-asserted-by":"publisher","first-page":"687","DOI":"10.3174\/ajnr.A6002","volume":"40","author":"F Cagnazzo","year":"2019","unstructured":"Cagnazzo F, Perrini P, Dargazanli C, Lefevre PH, Gascou G, Morganti R et al (2019) Treatment of Unruptured Distal Anterior Circulation Aneurysms with Flow-Diverter Stents: A Meta-Analysis. Am J Neuroradiol 40(4):687\u2013693. https:\/\/doi.org\/10.3174\/ajnr.A6002","journal-title":"Am J Neuroradiol"},{"key":"4080_CR12","doi-asserted-by":"publisher","first-page":"e421","DOI":"10.1016\/j.wneu.2021.07.055","volume":"154","author":"GBF Porto","year":"2021","unstructured":"Porto GBF, Al Kasab S, Sattur MG, Almallouhi E, Lajthia O, Casey MA et al (2021) Endovascular Management of Distal Anterior Cerebral Artery Aneurysms: A Multicenter Retrospective Review. World Neurosurg Oct 154:e421\u2013e427","journal-title":"World Neurosurg Oct"},{"key":"4080_CR13","doi-asserted-by":"publisher","first-page":"159101992513485","DOI":"10.1177\/15910199251348514","volume":"4","author":"G Salsano","year":"2025","unstructured":"Salsano G, Scarcia L, Claren\u00e7on F, Shotar E, Russo R, Bergui M et al (2025) Flow diverter stent for the treatment of ruptured distal anterior cerebral artery: A retrospective multicenter analysis from CRETA registry. Interventional Neuroradiol Aug 4:15910199251348514. https:\/\/doi.org\/10.1177\/15910199251348514","journal-title":"Interventional Neuroradiol Aug"},{"issue":"1","key":"4080_CR14","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.neurad.2018.07.006","volume":"46","author":"F Cagnazzo","year":"2019","unstructured":"Cagnazzo F, Lefevre PH, Mantilla D, Rouchaud A, Morganti R, Perrini P et al (2019) Patency of the supraclinoid internal carotid artery branches after flow diversion treatment. A meta-analysis. J Neuroradiol Feb 46(1):9\u201314","journal-title":"J Neuroradiol Feb"},{"issue":"2","key":"4080_CR15","doi-asserted-by":"publisher","first-page":"564","DOI":"10.3171\/2016.2.JNS152544","volume":"126","author":"B Daou","year":"2017","unstructured":"Daou B, Valle-Giler EP, Chalouhi N, Starke RM, Tjoumakaris S, Hasan D et al (2017) Patency of the posterior communicating artery following treatment with the Pipeline Embolization Device. J Neurosurg Feb; 126(2):564\u2013569","journal-title":"J Neurosurg"},{"issue":"6","key":"4080_CR16","doi-asserted-by":"publisher","first-page":"e001448","DOI":"10.1161\/SVIN.124.001448","volume":"25","author":"M Dibas","year":"2024","unstructured":"Dibas M, Vivanco-Suarez J, Galecio\u2010Castillo M, Lopes DK, Hanel RA, Rodriguez\u2010Calienes A et al (2024) Flow Diversion for Intracranial Aneurysms With Incorporated Branch: A Subanalysis From the SEASE International Registry. Stroke: Vascular Interventional Neurol Oct 25(6):e001448. https:\/\/doi.org\/10.1161\/SVIN.124.001448","journal-title":"Stroke: Vascular Interventional Neurol Oct"},{"issue":"10","key":"4080_CR17","doi-asserted-by":"publisher","first-page":"2004","DOI":"10.3174\/ajnr.A3075","volume":"33","author":"TE Darsaut","year":"2012","unstructured":"Darsaut TE, Bing F, Salazkin I, Gevry G, Raymond J (2012) Flow Diverters Can Occlude Aneurysms and Preserve Arterial Branches: A New Experimental Model. Am J Neuroradiol Nov 33(10):2004\u20132009","journal-title":"Am J Neuroradiol Nov"},{"key":"4080_CR18","doi-asserted-by":"publisher","first-page":"1368612","DOI":"10.3389\/fneur.2024.1368612","volume":"11","author":"A Khanafer","year":"2024","unstructured":"Khanafer A, Henkes H, Cohen J, Albi\u00f1a-Palmarola P, Gomori JM, Forsting M et al (2024) Endovascular treatment of distal anterior cerebral artery aneurysms using flow modulation devices: mid- and long-term results from a two-center study. Front Neurol Mar 11:15:1368612. https:\/\/doi.org\/10.3389\/fneur.2024.1368612","journal-title":"Front Neurol Mar"},{"key":"4080_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.aanat.2016.04.036","volume":"208","author":"K Cilliers","year":"2016","unstructured":"Cilliers K, Page BJ (2016) Detailed description of the anterior cerebral artery anomalies observed in a cadaver population. Annals Anat - Anatomischer Anzeiger Nov 208:1\u20138","journal-title":"Annals Anat - Anatomischer Anzeiger Nov"},{"issue":"8","key":"4080_CR20","doi-asserted-by":"publisher","first-page":"2167","DOI":"10.1007\/s00234-025-03678-y","volume":"67","author":"L Scarcia","year":"2025","unstructured":"Scarcia L, Claren\u00e7on F, Dmytriw AA, Shotar E, Jabbour P, Psychogios M et al (2025) Silk Vista Baby for the treatment of distal anterior cerebral artery aneurysms. Neuroradiol Aug 67(8):2167\u20132177. https:\/\/doi.org\/10.1007\/s00234-025-03678-y","journal-title":"Neuroradiol Aug"},{"key":"4080_CR21","doi-asserted-by":"publisher","unstructured":"G\u00fcnkan A, Vilardo M, Scarramal JPL, Elek A, Bocanegra-Becerra JE, Cardoso LJC, Dmytriw AA, Alexandre AM, Consoli A, Pereira VM, Onal Y, Claren\u00e7on F, Scarcia L (2026) Flow diversion for distal cerebral aneurysms: a systematic review and meta analysis. J Neurointerv Surg 18(4):1033\u20131041. https:\/\/doi.org\/10.1136\/jnis-2025-023362","DOI":"10.1136\/jnis-2025-023362"},{"issue":"10","key":"4080_CR22","first-page":"825","volume":"13","author":"AG Baptista","year":"1963","unstructured":"Baptista AG (1963) Studies on the arteries of the brain. Neurol Oct 13(10):825\u2013825","journal-title":"Neurol Oct"},{"key":"4080_CR23","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.jocn.2016.10.041","volume":"35","author":"E Nossek","year":"2017","unstructured":"Nossek E, Zumofen DW, Setton A, Potts MB, Raz E, Shapiro M et al (2017) Treatment of distal anterior cerebral artery aneurysms with the Pipeline Embolization Device. J Clin Neurosci Jan 35:133\u2013138","journal-title":"J Clin Neurosci Jan"},{"issue":"15","key":"4080_CR24","doi-asserted-by":"publisher","first-page":"1893","DOI":"10.3390\/diagnostics15151893","volume":"28","author":"G Triantafyllou","year":"2025","unstructured":"Triantafyllou G, Paschopoulos I, Kamoutsis K, Papadopoulos-Manolarakis P, Valenzuela-Fuenzalida JJ, Sanchis-Gimeno J et al (2025) Morphological Variations of the Anterior Cerebral Artery: A Systematic Review with Meta-Analysis of 85,316 Patients. Diagnostics Jul 28(15):1893","journal-title":"Diagnostics Jul"},{"issue":"6","key":"4080_CR25","doi-asserted-by":"publisher","first-page":"1751","DOI":"10.3171\/2018.7.JNS18654","volume":"131","author":"C Michelozzi","year":"2019","unstructured":"Michelozzi C, Darcourt J, Guenego A, Januel AC, Tall P, Gawlitza M et al (2019) Flow diversion treatment of complex bifurcation aneurysms beyond the circle of Willis: complications, aneurysm sac occlusion, reabsorption, recurrence, and jailed branch modification at follow-up. J Neurosurg Dec; 131(6):1751\u20131762","journal-title":"J Neurosurg"}],"container-title":["Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00234-026-04080-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00234-026-04080-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00234-026-04080-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T05:14:36Z","timestamp":1784092476000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00234-026-04080-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,6]]},"references-count":25,"alternative-id":["4080"],"URL":"https:\/\/doi.org\/10.1007\/s00234-026-04080-y","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-9488266\/v1","asserted-by":"object"}]},"ISSN":["0028-3940","1432-1920"],"issn-type":[{"value":"0028-3940","type":"print"},{"value":"1432-1920","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,6]]},"assertion":[{"value":"21 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 June 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All procedures performed in the studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":1,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Informed consent was waived in consideration of the retrospective nature of this study.","order":2,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"LS: unrelated to the current study, Penumbra (paid lectures). FS: Outside the submitted work received lecturer\u2019s fee from Idorsia Pharmaceuticals for the past 36 months. OG: Outside the submitted work, MicroVention proctor for the WEB device, Stryker consultant, Route 92 consultant. ML: Unrestricted educational grants from Medtronic and Stryker; consulting agreement with Aeaean Advisers, Metis Innovative, Genomadix, AIDoc and Arsenal Medical; equity interest in Proprio, Stroke Diagnostics, Apertur, Stereotaxis, Fluid Biomed, Synchron and Hyperion Surgical; editorial board of Journal of NeuroInterventional Surgery; Data safety monitoring board of Arsenal Medical. AMA: educational grants from Medtronic, Stryker, Balt and Microvention\/Terumo unrelated to the current study. AP: educational grants from Medtronic, Stryker, Balt and Microvention\/Terumo unrelated to the current study. AEH: Consultant\/Speaker: Medtronic, Microvention, Stryker, Penumbra, Cerenovus, Genentech, GE Healthcare, Scientia, Balt, Viz.ai, Insera therapeutics, Proximie, NeuroVasc, NovaSignal, Vesalio, Rapid Medical, Imperative Care, Galaxy Therapeutics, Route 92, Perfuze, CorTech, Shockwave, Toro and Xcath. Principal Investigator: COMPLETE study \u2013 Penumbra, LVO SYNCHRONISE \u2013 Viz.ai, MARRS - Perfuze, RESCUE - ICAD - Medtronic. Steering Committee\/Publication committee member: SELECT, DAWN, SELECT 2, EXPEDITE II, EMBOLISE, CLEAR, ENVI, DELPHI, DISTALS. DSMB - COMAND trial. ML Unrestricted educational grants from Medtronic and Stryker; consulting agreement with Aeaean Advisers, Metis Innovative, Genomadix, AIDoc and Arsenal Medical; equity interest in Proprio, Stroke Diagnostics, Apertur, Stereotaxis, Fluid Biomed, Synchron and Hyperion Surgical; editorial board of Journal of NeuroInterventional Surgery; Data safety monitoring board of Arsenal Medical. FC reports conflicts of interest with Medtronic, Balt Extrusion (consultant), ClinSearch (core lab), Penumbra, Stryker (payment for reading) and Artedrone (Board) ; all not directly related to the present work. CC consultant for Medtronic, Microvention, Cerenovus, Stryker, Anaconda, unrelated to the current study.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}