{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:47:13Z","timestamp":1792025233401,"version":"4.4.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuroradiology"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the radiographic and clinical outcomes of adjunctive middle meningeal artery embolization (MMAE) performed with the Scepter Mini dual-lumen balloon microcatheter following burr-hole evacuation for chronic subdural hematoma (cSDH), and to explore the feasibility of characterizing distal embolic penetration using the proposed MMA Embolization Penetration Score (MMA-EPS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective multicenter matched cohort study included consecutive patients with cSDH treated with burr-hole evacuation followed by adjunctive MMAE using the Scepter Mini and Onyx\u2122 18. A matched historical cohort treated with burr-hole evacuation alone served as controls. The primary endpoint was longitudinal hematoma thickness regression on serial computed tomography. Secondary endpoints included functional outcome, recurrence, all-cause mortality, and procedural safety.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty-two patients with 38 embolized cSDHs were compared with 22 matched controls comprising 38 cSDHs. All embolized hematomas achieved MMA-EPS Grade 3 or 4 and demonstrated complete radiographic resolution by 6 months, whereas residual hematoma persisted in controls (0.0\u2009\u00b1\u20090.0 vs. 0.7\u2009\u00b1\u20090.9\u00a0mm). Favorable functional outcome (mRS 0\u20132) at 6 months was achieved in 86.4% versus 45.5% of patients. Exploratory analyses showed numerically lower recurrence (4.5% vs. 13.6%) and all-cause mortality (0% vs. 13.6%) following MMAE; however, the study was not powered to assess differences in these endpoints. Technical success was achieved in all embolizations without major procedure-related complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Adjunctive MMAE using the Scepter Mini dual-lumen balloon microcatheter was associated with accelerated hematoma resolution, improved functional recovery, and an excellent procedural safety profile compared with burr-hole evacuation alone.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00234-026-04203-5","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:11:51Z","timestamp":1792023111000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Longitudinal hematoma resolution after burr-hole evacuation with adjunctive scepter mini-assisted middle meningeal artery embolization: A multicenter matched cohort study"],"prefix":"10.1007","author":[{"given":"Mohamad","family":"Alheer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter B","family":"Sporns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Broocks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mete","family":"Dadak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tawfik","family":"Moher Alsady","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bayan","family":"Alhaj Moustafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy A","family":"G\u00f6rtz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Nimsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Kirchleitner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asmaa","family":"Alhaj Moustafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"D\u00f6ring","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9298-2897","authenticated-orcid":false,"given":"Mike P","family":"Wattjes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Kemmling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4233-8048","authenticated-orcid":false,"given":"Mohammad","family":"Almohammad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,14]]},"reference":[{"key":"4203_CR1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-017-0881-y","volume":"14","author":"E Edlmann","year":"2017","unstructured":"Edlmann E, Giorgi-Coll S, Whitfield PC et al (2017) Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy. 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Given the retrospective design and the exclusive use of fully anonymized data, the requirement for informed consent was waived. In accordance with applicable regulations, separate ethical approval was not required at the participating centers. All data were handled in compliance with institutional policies and national data protection legislation.","order":1,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ch. Nimsky: Consultant for Brainlab, GE BK Medical, and Zeiss, outside the submitted work. All other authors declare no conflicts of interest.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}