{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T19:14:04Z","timestamp":1787944444682,"version":"build-2784847793"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2022,8,21]],"date-time":"2022-08-21T00:00:00Z","timestamp":1661040000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,8,21]],"date-time":"2022-08-21T00:00:00Z","timestamp":1661040000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Urolithiasis"],"DOI":"10.1007\/s00240-022-01356-9","type":"journal-article","created":{"date-parts":[[2022,8,21]],"date-time":"2022-08-21T05:02:26Z","timestamp":1661058146000},"page":"679-684","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A mouse model of type B cystinuria due to spontaneous mutation in FVB\/NJcl mice"],"prefix":"10.1007","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0162-4774","authenticated-orcid":false,"given":"Hayato","family":"Sasaki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeru","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koki","family":"Hiura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7971-3024","authenticated-orcid":false,"given":"Nobuya","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,8,21]]},"reference":[{"key":"1356_CR1","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.mam.2012.10.007","volume":"34","author":"D Fotiadis","year":"2013","unstructured":"Fotiadis D, Kanai Y, Palac\u00edn M (2013) The SLC3 and SLC7 families of amino acid transporters. Mol Asp Med 34:139\u2013158. https:\/\/doi.org\/10.1016\/j.mam.2012.10.007","journal-title":"Mol Asp Med"},{"key":"1356_CR2","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1136\/jmg.2004.022244","volume":"42","author":"M Font-Llitjos","year":"2005","unstructured":"Font-Llitjos M (2005) New insights into cystinuria: 40 new mutations, genotype-phenotype correlation, and digenic inheritance causing partial phenotype. J Med Genet 42:58\u201368. https:\/\/doi.org\/10.1136\/jmg.2004.022244","journal-title":"J Med Genet"},{"key":"1356_CR3","doi-asserted-by":"publisher","first-page":"2547","DOI":"10.1097\/01.asn.0000029586.17680.e5","volume":"13","author":"LD Strologo","year":"2002","unstructured":"Strologo LD, Pras E, Pontesilli C, Beccia E, Ricci-Barbini V, de Sanctis L et al (2002) Comparison between SLC3A1 and SLC7A9 cystinuria patients and carriers: a need for a new classification. J Am Soc Nephrol 13:2547\u20132553. https:\/\/doi.org\/10.1097\/01.asn.0000029586.17680.e5","journal-title":"J Am Soc Nephrol"},{"key":"1356_CR4","doi-asserted-by":"publisher","first-page":"1576","DOI":"10.1016\/s0022-5347(01)65451-x","volume":"156","author":"GK Chow","year":"1996","unstructured":"Chow GK, Streem SB (1996) Medical treatment of cystinuria: results of contemporary clinical practice. J Urol 156:1576\u20131578. https:\/\/doi.org\/10.1016\/s0022-5347(01)65451-x","journal-title":"J Urol"},{"key":"1356_CR5","doi-asserted-by":"publisher","first-page":"71","DOI":"10.5582\/irdr.2020.03006","volume":"9","author":"M Moussa","year":"2020","unstructured":"Moussa M, Papatsoris AG, Abou Chakra M, Moussa Y (2020) Update on cystine stones: current and future concepts in treatment. Intractable rare Dis Res 9:71\u201378. https:\/\/doi.org\/10.5582\/irdr.2020.03006","journal-title":"Intractable rare Dis Res"},{"key":"1356_CR6","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.semnephrol.2008.01.011","volume":"28","author":"A Mattoo","year":"2008","unstructured":"Mattoo A, Goldfarb DS (2008) Cystinuria. Semin Nephrol 28:181\u2013191. https:\/\/doi.org\/10.1016\/j.semnephrol.2008.01.011","journal-title":"Semin Nephrol"},{"key":"1356_CR7","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1038\/nm.4280","volume":"23","author":"T Zee","year":"2017","unstructured":"Zee T, Bose N, Zee J, Beck JN, Yang S, Parihar J et al (2017) \u03b1-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria. Nat Med 23:288\u2013290. https:\/\/doi.org\/10.1038\/nm.4280","journal-title":"Nat Med"},{"key":"1356_CR8","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s11926-015-0510-7","volume":"17","author":"MH Lee","year":"2015","unstructured":"Lee MH, Sahota A, Ward MD, Goldfarb DS (2015) Cystine growth inhibition through molecular mimicry: a new paradigm for the prevention of crystal diseases. Curr Rheumatol Rep 17:33. https:\/\/doi.org\/10.1007\/s11926-015-0510-7","journal-title":"Curr Rheumatol Rep"},{"key":"1356_CR9","doi-asserted-by":"publisher","first-page":"1806","DOI":"10.1101\/gr.2825804","volume":"14","author":"PM Petkov","year":"2004","unstructured":"Petkov PM, Ding Y, Cassell MA, Zhang W, Wagner G, Sargent EE et al (2004) An efficient SNP system for mouse genome scanning and elucidating strain relationships. Genome Res 14:1806\u20131811. https:\/\/doi.org\/10.1101\/gr.2825804","journal-title":"Genome Res"},{"key":"1356_CR10","doi-asserted-by":"publisher","first-page":"2065","DOI":"10.1073\/pnas.88.6.2065","volume":"88","author":"M Taketo","year":"1991","unstructured":"Taketo M, Schroeder AC, Mobraaten LE, Gunning KB, Hanten G, Fox RR et al (1991) FVB\/N: an inbred mouse strain preferable for transgenic analyses. Proc Natl Acad Sci 88:2065\u20132069. https:\/\/doi.org\/10.1073\/pnas.88.6.2065","journal-title":"Proc Natl Acad Sci"},{"key":"1356_CR11","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1177\/019262339602400606","volume":"24","author":"JF Mahler","year":"1996","unstructured":"Mahler JF, Stokes W, Mann PC, Takaoka M, Maronpot RR (1996) Spontaneous lesions in aging FVB\/N mice. Toxicol Pathol 24:710\u2013716. https:\/\/doi.org\/10.1177\/019262339602400606","journal-title":"Toxicol Pathol"},{"key":"1356_CR12","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/S0361-9230(01)00635-9","volume":"57","author":"YS Mineur","year":"2002","unstructured":"Mineur YS, Crusio WE (2002) Behavioral and neuroanatomical characterization of FVB\/N inbred mice. Brain Res Bull 57:41\u201347. https:\/\/doi.org\/10.1016\/S0361-9230(01)00635-9","journal-title":"Brain Res Bull"},{"key":"1356_CR13","first-page":"253","volume":"58","author":"P Huang","year":"2008","unstructured":"Huang P, Duda DG, Jain RK, Fukumura D (2008) Histopathologic findings and establishment of novel tumor lines from spontaneous tumors in FVB\/N mice. Comp Med 58:253\u2013263","journal-title":"Comp Med"},{"key":"1356_CR14","doi-asserted-by":"publisher","first-page":"2097","DOI":"10.1093\/hmg\/ddg228","volume":"12","author":"L Feliubadalo","year":"2003","unstructured":"Feliubadalo L (2003) Slc7a9-deficient mice develop cystinuria non-I and cystine urolithiasis. Hum Mol Genet 12:2097\u20132108. https:\/\/doi.org\/10.1093\/hmg\/ddg228","journal-title":"Hum Mol Genet"},{"key":"1356_CR15","doi-asserted-by":"publisher","first-page":"2109","DOI":"10.1093\/hmg\/ddg189","volume":"12","author":"T Peters","year":"2003","unstructured":"Peters T (2003) A mouse model for cystinuria type I. Hum Mol Genet 12:2109\u20132120. https:\/\/doi.org\/10.1093\/hmg\/ddg189","journal-title":"Hum Mol Genet"},{"key":"1356_CR16","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/s11255-009-9597-y","volume":"42","author":"M Ercolani","year":"2010","unstructured":"Ercolani M, Sahota A, Schuler C, Yang M, Evan AP, Reimer D, Barone JG, Tischfield JA, Levin RM (2010) Bladder outlet obstruction in male cystinuria mice. Int Urol Nephrol 42:57\u201363. https:\/\/doi.org\/10.1007\/s11255-009-9597-y","journal-title":"Int Urol Nephrol"},{"key":"1356_CR17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0102700","volume":"9","author":"M Livrozet","year":"2014","unstructured":"Livrozet M, Vandermeersch S, Mesnard L, Thioulouse E, Jaubert J, Boffa J-J et al (2014) An animal model of type a cystinuria due to spontaneous mutation in 129S2\/SvPasCrl mice. PLoS\u00a0One 9:e102700. https:\/\/doi.org\/10.1371\/journal.pone.0102700","journal-title":"PLoS\u00a0One"},{"key":"1356_CR18","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/s00240-018-1101-7","volume":"47","author":"A Sahota","year":"2019","unstructured":"Sahota A, Tischfield JA, Goldfarb DS, Ward MD, Hu L (2019) Cystinuria: genetic aspects, mouse models, and a new approach to therapy. Urolithiasis 47:57\u201366. https:\/\/doi.org\/10.1007\/s00240-018-1101-7","journal-title":"Urolithiasis"},{"key":"1356_CR19","doi-asserted-by":"publisher","first-page":"18249","DOI":"10.1073\/pnas.0607218103","volume":"103","author":"EC Salido","year":"2006","unstructured":"Salido EC, Li XM, Lu Y, Wang X, Santana A, Roy-Chowdhury N, Torres A, Shapiro LJ, Roy-Chowdhury J (2006) Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer. Proc Natl Acad Sci 103:18249\u201318254. https:\/\/doi.org\/10.1073\/pnas.0607218103","journal-title":"Proc Natl Acad Sci"}],"container-title":["Urolithiasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00240-022-01356-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00240-022-01356-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00240-022-01356-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T09:06:33Z","timestamp":1666256793000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00240-022-01356-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,21]]},"references-count":19,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["1356"],"URL":"https:\/\/doi.org\/10.1007\/s00240-022-01356-9","relation":{},"ISSN":["2194-7236"],"issn-type":[{"value":"2194-7236","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,21]]},"assertion":[{"value":"13 July 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 August 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 August 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All research was conducted according to the Regulations for the Care and Use of Laboratory Animals of Kitasato University. The animal experimentation protocol was approved by the President of Kitasato University based on the judgment made by the Institutional Animal Care and Use Committee of Kitasato University (Approval ID: 21-055).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}