{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:18:51Z","timestamp":1772119131424,"version":"3.50.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T00:00:00Z","timestamp":1711152000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T00:00:00Z","timestamp":1711152000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"University of Health Sciences"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Urolithiasis"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>To evaluate the optimal duration of Medical Expulsive Therapy (MET) application for distal ureteric stones on a time period based manner. 89 patients with 5\u201310\u00a0mm distal ureter stones received tamsulosin (0.4\u00a0mg) for MET and diclofenac sodium (75\u00a0mg) for analgesia. Patients were evaluated once a week for 4 weeks. Radiologic stone passage was evaluated by kidney ureter bladder (KUB) and ultasonography where non-contrast computed tomography (NCCT) was also performed if needed. While 23 cases (28.4%) were SF after first week, 23 were SF (28.4%) after 2 weeks, 9 cases (11.1%) after 3 and lastly 7 cases (8.6%) became SF after four weeks. Nineteen (23.5%) cases were not SF after 4\u00a0weeks. A positive relationship was found between the time period elapsed for stone passage and ureteral wall thickness (UWT) along with the degree of hydronephrosis. In addition, mean number of renal colics and emergency department (ED) visits were found to be higher in patients passing stones in the 4th week along with the ones who could not despite MET. SFR for distal ureteric stones sizing 5\u201310\u00a0mm was higher within the first 3 weeks under MET application. Thus, waiting for a longer period of time may result in increased analgesic and unnecessary MET treatment with increased risk of emergency department visits and additional costs as well. We believe that other options could be considered in such cases who are not SF at the end of the first 3 weeks.<\/jats:p>","DOI":"10.1007\/s00240-024-01548-5","type":"journal-article","created":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T08:01:59Z","timestamp":1711180919000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Optimal duration of medical expulsive therapy for lower ureteral stones: a critical evaluation"],"prefix":"10.1007","volume":"52","author":[{"given":"Erhan","family":"Erdo\u011fan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gamze","family":"\u015eim\u015fek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alper","family":"A\u015f\u0131k","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hikmet","family":"Ya\u015far","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cahit","family":"\u015eahin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kemal","family":"Sar\u0131ca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,3,23]]},"reference":[{"key":"1548_CR1","unstructured":"Kodama H Ohno Y (1989) Descriptive epidemiology of urolithiasis. Hinyokika Kiyo 35(6): 923\u201334 http:\/\/hdl.handle.net\/2433\/116578"},{"key":"1548_CR2","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1159\/000474289","volume":"24","author":"WA H\u00fcbner","year":"1993","unstructured":"H\u00fcbner WA, Irby P, Stoller ML (1993) Natural history and current concepts for the treatment of small ureteral calculi. Eur Urol 24:172\u2013176. https:\/\/doi.org\/10.1159\/000474289","journal-title":"Eur Urol"},{"key":"1548_CR3","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/S0022-5347(17)40037-1","volume":"143","author":"AR Crowley","year":"1990","unstructured":"Crowley AR, Byrne JC, Vaughan ED Jr, Marion DN (1990) The effect of acute obstruction on ureteral function. 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J Urol 178:2418\u20132434. https:\/\/doi.org\/10.1016\/j.eururo.2007.09.039","journal-title":"J Urol"},{"issue":"11\u201312","key":"1548_CR6","doi-asserted-by":"publisher","first-page":"442","DOI":"10.5489\/cuaj.2472","volume":"8","author":"D Bos","year":"2014","unstructured":"Bos D, Kapoor A (2014) Update on medical expulsive therapy for distal ureteral stones: beyond alpha-blockers. Can Urol Assoc J 8(11\u201312):442\u2013445. https:\/\/doi.org\/10.5489\/cuaj.2472","journal-title":"Can Urol Assoc J"},{"issue":"1","key":"1548_CR7","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.euf.2017.01.002","volume":"3","author":"T Knoll","year":"2017","unstructured":"Knoll T, T\u00fcrk C (2017) The role of medical expulsive therapy for ureteral stones: pro MET. Eur Urol Focus 3(1):3\u20134. https:\/\/doi.org\/10.1016\/j.euf.2017.01.002","journal-title":"Eur Urol Focus"},{"issue":"S1","key":"1548_CR8","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1111\/bcpt.13613","volume":"130","author":"I Lim","year":"2022","unstructured":"Lim I et al (2022) Current and emerging pharmacological targets for medical expulsive therapy. Basic Clin Phamacol Toxicol 130(S1):16\u201322. https:\/\/doi.org\/10.1111\/bcpt.13613","journal-title":"Basic Clin Phamacol Toxicol"},{"issue":"9991","key":"1548_CR9","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/S0140-6736(15)60933-3","volume":"386","author":"R Pickard","year":"2015","unstructured":"Pickard R et al (2015) Lancet, medical expulsive therapy in adults with ureteric colic: a multicentre, randomised, placebo-controlled trial. 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