{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:07:16Z","timestamp":1790885236889,"version":"4.1.0"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2008,7,26]],"date-time":"2008-07-26T00:00:00Z","timestamp":1217030400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Environ Contam Toxicol"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1007\/s00244-008-9194-6","type":"journal-article","created":{"date-parts":[[2008,7,25]],"date-time":"2008-07-25T15:36:27Z","timestamp":1217000187000},"page":"338-349","source":"Crossref","is-referenced-by-count":347,"title":["Studies on the Toxicological Effects of PFOA and PFOS on Rats Using Histological Observation and Chemical Analysis"],"prefix":"10.1007","volume":"56","author":[{"given":"Lin","family":"Cui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qun-fang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-yang","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-jie","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gui-bin","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,7,26]]},"reference":[{"key":"9194_CR1","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1093\/carcin\/11.11.1899","volume":"11","author":"AG Abdellatif","year":"1990","unstructured":"Abdellatif AG, Preat V (1990) Peroxisome proliferation and modulation of rat liver carcinogenesis by 2, 4-dichlorophenoxyacetic acid, 2, 4, 5-trichlorophenoxyacetic acid, perfluorooctanoic acid and nafenopin. Carcinogenesis 11:1899\u20131902. doi: 10.1093\/carcin\/11.11.1899","journal-title":"Carcinogenesis"},{"key":"9194_CR2","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/0041-008X(91)90257-F","volume":"111","author":"AG Abdellatif","year":"1999","unstructured":"Abdellatif AG, Preat V (1999) The modulation of rat liver carcinogenesis by perfluorooctanoic acid, a peroxisome proliferator. Toxicol Appl Pharm 111:530\u2013537. doi: 10.1016\/0041-008X(91)90257-F","journal-title":"Toxicol Appl Pharm"},{"key":"9194_CR3","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.tox.2006.08.004","volume":"227","author":"ME Andersen","year":"2006","unstructured":"Andersen ME, Clewell HJIII, Tan YM, Butenhoff JL, Olsen GW (2006) Pharmacokinetic modeling of saturable, renal resorption of perfluoroalkylacids in monkeys: probing the determinants of long plasma half-lives. Toxicology 227:156\u2013164. doi: 10.1016\/j.tox.2006.08.004","journal-title":"Toxicology"},{"key":"9194_CR4","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1289\/ehp.6128","volume":"11","author":"ME Austin","year":"2003","unstructured":"Austin ME, Kasturi BS, Barber M, Kannan K, MohanKumar PS, MohanKumar SMJ (2003) Neuroendocrine effects of perfluorooctane sulfonate in rats. Environ Health Perspect 11:1485\u20131489","journal-title":"Environ Health Perspect"},{"key":"9194_CR5","first-page":"L367","volume":"262","author":"JJ Batenburg","year":"1992","unstructured":"Batenburg JJ (1992) Surfactant phospholipids: synthesis and storage. Am J Physiol 262:L367\u2013L385","journal-title":"Am J Physiol"},{"key":"9194_CR6","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0378-4274(01)00466-0","volume":"129","author":"J Berthiaume","year":"2002","unstructured":"Berthiaume J, Wallace KB (2002) Perfluorooctanoate, perfluorooctane sulfonate and N-ethyl-perfluorooctanesulfonamido ethanol: Peroxisome proliferation and mitochondrial biogenenesis. Toxicol Lett 129:23\u201332. doi: 10.1016\/S0378-4274(01)00466-0","journal-title":"Toxicol Lett"},{"key":"9194_CR7","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1093\/toxsci\/kfh302","volume":"82","author":"JL Butenhoff","year":"2004","unstructured":"Butenhoff JL, Kennedy JGL, Hinderliter PM et al (2004) Pharmacokinetics of perfluorooctanoate in Cynomolgus monkeys. Toxicol Sci 82:394\u2013406. doi: 10.1093\/toxsci\/kfh302","journal-title":"Toxicol Sci"},{"key":"9194_CR8","first-page":"25","volume":"66","author":"JL Butenhoff","year":"2002","unstructured":"Butenhoff JL, York R, Seacat A, Luebker D (2002) Perfluorooctanesulfonate-induced perinatal mortality in rat pups is associated with a steep dose-response. Toxicologist 66:25","journal-title":"Toxicologist"},{"key":"9194_CR9","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/jbt.6","volume":"15","author":"LC Chen","year":"2001","unstructured":"Chen LC, Tatum V, Glauert HP, Chow CK (2001) Peroxisome proliferator perfluorodecanoic acid alters glutathione and related enzymes. J Biochem Mol Toxicol 15:107\u2013112. doi: 10.1002\/jbt.6","journal-title":"J Biochem Mol Toxicol"},{"key":"9194_CR10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/PL00007554","volume":"175","author":"LAJM Creuwels","year":"1997","unstructured":"Creuwels LAJM, van Golde LMG, Haagsman HP (1997) The pulmonary surfactant system: biochemical and clinical aspects. Lung 175:1\u201339. doi: 10.1007\/PL00007554","journal-title":"Lung"},{"key":"9194_CR11","unstructured":"Dean WP, Jessup DC, Thompson G, Romig G, Powell D (1978) Fluorad fluorochemical surfactant FC\u201395 acute oral toxicity (LD50) study in rats. Study No.137-083. International Research and Development Corporation, Mattawan, MI"},{"key":"9194_CR12","first-page":"203","volume-title":"The handbook of environmental chemistry","author":"JW DePierre","year":"2002","unstructured":"DePierre JW (2002) Effects on rodents of perfluorofatty acids. In: Neilson AH (ed) The handbook of environmental chemistry. Springer-Verlag, Berlin, pp 203\u2013248"},{"key":"9194_CR13","volume-title":"Excretion and disposition of 14C-ammonium perfluorooctanoate in male and female rats, mice, hamsters, and rabbits. US EPA Public Docket AR-226","author":"DuPont Haskell Laboratory","year":"1982","unstructured":"DuPont Haskell Laboratory (1982) Excretion and disposition of 14C-ammonium perfluorooctanoate in male and female rats, mice, hamsters, and rabbits. US EPA Public Docket AR-226. US Environmental Protection agency, Washington, DC"},{"key":"9194_CR14","first-page":"468","volume":"39","author":"SS Dzhekova","year":"2001","unstructured":"Dzhekova SS, Bogdanska J, Stojkova Z (2001) Peroxisome proliferators: their biological and toxicological effects. Clin Chem Lab Med 39:468\u2013474. doi: 10.1515\/CCLM.2001.076","journal-title":"Clin Chem Lab Med"},{"key":"9194_CR15","first-page":"L748","volume":"280","author":"AB Fisher","year":"2001","unstructured":"Fisher AB, Dodia C (2001) Lysosomal-type PLA2 and turnover of alveolar DPPC. Am J Physiol 280:L748\u2013L754","journal-title":"Am J Physiol"},{"key":"9194_CR16","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1021\/es001834k","volume":"35","author":"JP Giesy","year":"2001","unstructured":"Giesy JP, Kannan K (2001) Global distribution of perfluorooctane sulfonate in wildlife. Environ Sci Technol 35:1339\u20131342. doi: 10.1021\/es001834k","journal-title":"Environ Sci Technol"},{"key":"9194_CR17","doi-asserted-by":"crossref","first-page":"146A","DOI":"10.1021\/es022253t","volume":"36","author":"JP Giesy","year":"2002","unstructured":"Giesy JP, Kannan K (2002) Perfluorochemical surfactants in the environment. Environ Sci Technol 36:146A\u2013152A","journal-title":"Environ Sci Technol"},{"key":"9194_CR18","unstructured":"Goldenthal EI, Jessup DC, Geil RG, Mehring JS (1978) Ninety-day subacute rat toxicity study. Study No. 137-085. International Research and development Corporation, Mattawan, MI"},{"key":"9194_CR61","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1002\/bdrb.10046","volume":"68","author":"RC Grasty","year":"2003","unstructured":"Grasty RC, Grey BE, Lau CS, Rogers JM (2003) Prenatal window of susceptibility to perfluorooctane sulfonate-induced neonatal mortality in the Sprague-Dawley rat. Birth Defects Res Part B-Dev Reprod Toxicol 68:465\u2013471","journal-title":"Birth Defects Res Part B-Dev Reprod Toxicol"},{"key":"9194_CR19","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/toxsci\/kfj011","volume":"89","author":"KS Guruge","year":"2007","unstructured":"Guruge KS, Yeung LWY, Yamanaka N et al (2007) Gene expression profiles in rat liver treated with perfluorooctanoic acid (PFOA). Toxicol Sci 89:93\u2013107. doi: 10.1093\/toxsci\/kfj011","journal-title":"Toxicol Sci"},{"key":"9194_CR20","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S1095-6433(01)00324-5","volume":"129","author":"M Hallman","year":"2001","unstructured":"Hallman M, Glumoff V, Ramet M (2001) Surfactant in respiratory distress syndrome and lung injury. Comp Biochem Physiol A: Mol Integr Physiol 129:287\u2013294. doi: 10.1016\/S1095-6433(01)00324-5","journal-title":"Comp Biochem Physiol A: Mol Integr Physiol"},{"key":"9194_CR21","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1081\/DCT-52547","volume":"28","author":"X Han","year":"2005","unstructured":"Han X, Kermper RA, Jepson GW (2005) Subcellular distribution and protein binding of perfluorooctanoic acid in rat liver and kidney. Drug Chem Toxicol 28:197\u2013209. doi: 10.1081\/DCT-200052547","journal-title":"Drug Chem Toxicol"},{"key":"9194_CR22","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1021\/tx034005w","volume":"16","author":"X Han","year":"2003","unstructured":"Han X, Snow TA, Kemper RA, Jepson GW (2003) Binding of perfluorooctanoic acid to rat and human plasma proteins. Chem Res Toxicol 16:775\u2013781. doi: 10.1021\/tx034005w","journal-title":"Chem Res Toxicol"},{"key":"9194_CR23","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1021\/es001489z","volume":"35","author":"KJ Hansen","year":"2001","unstructured":"Hansen KJ, Clemen LA, Ellefson ME, Johnson HO (2001) Compound-specific, quantitative characterization of organic fluorochemicals in biological matrices. Environ Sci Technol 35:766\u2013770. doi: 10.1021\/es001489z","journal-title":"Environ Sci Technol"},{"key":"9194_CR24","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.envres.2004.12.003","volume":"99","author":"K Harada","year":"2005","unstructured":"Harada K, Inoue K, Morikawa A, Yoshinaga T, Saito N, Koizumi A (2005) Renal clearance of perfluorooctane sulfonate and perfluorooctanoate in humans and their species-specific excretion. Environ Res 99:253\u2013261. doi: 10.1016\/j.envres.2004.12.003","journal-title":"Environ Res"},{"key":"9194_CR25","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0005-2760(92)90258-W","volume":"1128","author":"B Haughom","year":"1992","unstructured":"Haughom B, Spydevold \u00d8 (1992) The mechanism underlying the hypolipemic effect of perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid. Biochim Biophys Acta 1128:65\u201372","journal-title":"Biochim Biophys Acta"},{"key":"9194_CR26","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.3109\/00498259309059427","volume":"23","author":"M Hosokawa","year":"1993","unstructured":"Hosokawa M, Satoh T (1993) Differences in the induction of carboxylesterase isozymes in rat iver microsomes by perfluorinated fatty acids. Xenobiotica 23:1125\u20131133","journal-title":"Xenobiotica"},{"key":"9194_CR27","doi-asserted-by":"crossref","first-page":"4138","DOI":"10.1021\/es060233b","volume":"40","author":"M Houde","year":"2006","unstructured":"Houde M, Martin JW, Letcher RJ, Solomon KR, Muir DG (2006) Biological monitoring of polyfluoroalkyl substances: a review. Environ Sci Technol 40:4138\u20134144. doi: 10.1021\/es060233b","journal-title":"Environ Sci Technol"},{"key":"9194_CR28","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.etap.2004.04.008","volume":"19","author":"WY Hu","year":"2005","unstructured":"Hu WY, Jones PD, Celius T, Giesy JP (2005) Identification of genes responsive to PFOS using gene expression profiling. Environ Toxicol Pharmcol 19:57\u201370. doi: 10.1016\/j.etap.2004.04.008","journal-title":"Environ Toxicol Pharmcol"},{"key":"9194_CR29","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1093\/oxfordjournals.jbchem.a135302","volume":"98","author":"T Ikeda","year":"1985","unstructured":"Ikeda T, Aiba K, Fukuda K, Tanaka M (1985) The induction of peroxisome proliferation in rat liver by perfluorinated fatty acids, metabolically inert derivatives of fatty acids. J Biochem 98:475\u2013482","journal-title":"J Biochem"},{"key":"9194_CR30","unstructured":"Johnson JD, Gibson SJ, Ober RE (1979) Extent and route of excretion and tissue distribution of total carbon-14 in rats after a single i.v. dose of FC-95-14C. Project No. 8900310200, Riker Laboratories, Inc., St. Paul, MN [EPA Docket No. 8(e)HQ-1180-00374]"},{"key":"9194_CR31","doi-asserted-by":"crossref","first-page":"4489","DOI":"10.1021\/es0493446","volume":"38","author":"K Kannan","year":"2004","unstructured":"Kannan K, Corsolini S, Falandysz J et al (2004) Perfluorooctanesulfonate and related fluorochemicals in human blood from several countries. Environ Sci Technol 38:4489\u20134495. doi: 10.1021\/es0493446","journal-title":"Environ Sci Technol"},{"key":"9194_CR32","unstructured":"Kemper R (2003) Perfluorooctanoic acid: toxicokinetics in the rat. Project ID: DuPont 7473. US EPA public docket, administrative record AR-226-1499"},{"key":"9194_CR33","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1080\/10408440490464705","volume":"34","author":"GL Kennedy","year":"2004","unstructured":"Kennedy GL, Butenhoff JL, Olsen GW et al (2004) The toxicology of perfluorooctanoate. Crit Rev Toxicol 34:351\u2013384. doi: 10.1080\/10408440490464705","journal-title":"Crit Rev Toxicol"},{"key":"9194_CR34","first-page":"2445","volume":"9","author":"BD Key","year":"1997","unstructured":"Key BD, Howell RD, Criddle CS (1997) Fluorinated organics in the biosphere. Environ Sci Technol 9:2445\u20132554. doi: 10.1021\/es961007c","journal-title":"Environ Sci Technol"},{"key":"9194_CR35","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.envres.2004.12.003","volume":"99","author":"H Kouji","year":"2005","unstructured":"Kouji H, Kayoko I, Akiko M, Takeo Y, Norimitsu S, Akio K (2005) Renal clearance of perfluorooctane sulfonate and perfluorooctanoate in humans and their species-specific excretion. Environ Res 99:253\u2013261. doi: 10.1016\/j.envres.2004.12.003","journal-title":"Environ Res"},{"key":"9194_CR36","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0009-2797(02)00006-6","volume":"139","author":"N Kudo","year":"2002","unstructured":"Kudo N, Katakura M, Sato Y, Kawashima Y (2002) Sex hormone-regulated renal transport of perfluorooctanoic acid. Chem Biol Interact 139:301\u2013316. doi: 10.1016\/S0009-2797(02)00006-6","journal-title":"Chem Biol Interact"},{"key":"9194_CR37","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.taap.2003.11.031","volume":"198","author":"C Lau","year":"2004","unstructured":"Lau C, Butenhoff JL, Rogers JM (2004) The developmental toxicity of perfluoroalkyl acids and their derivatives. Toxicol Appl Pharm 198:231\u2013241. doi: 10.1016\/j.taap.2003.11.031","journal-title":"Toxicol Appl Pharm"},{"key":"9194_CR38","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/toxsci\/kfg122","volume":"74","author":"C Lau","year":"2003","unstructured":"Lau C, Thibodeaux JR, Hanson RG et al (2003) Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. II: Postnatal evaluation. Toxicol Sci 74:382\u2013392. doi: 10.1093\/toxsci\/kfg122","journal-title":"Toxicol Sci"},{"key":"9194_CR39","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0300-483X(02)00081-1","volume":"176","author":"DJ Luebker","year":"2002","unstructured":"Luebker DJ, Hansen KJ, Bass NM, Buttenhoff JL, Seacat AM (2002) Interactions of fluorochemicals with rat liver fatty acid-binding protein. Toxicology 176:175\u2013185. doi: 10.1016\/S0300-483X(02)00081-1","journal-title":"Toxicology"},{"key":"9194_CR40","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1006\/taap.2000.9111","volume":"171","author":"ML O\u2019Brien","year":"2001","unstructured":"O\u2019Brien ML, Cunningham ML, Spear BT, Glauert HP (2001) Effects of peroxisome proliferators on glutathione and glutathione-related enzymes in rats and hamsters. Toxicol Appl Pharmacol 171:27\u201337. doi: 10.1006\/taap.2000.9111","journal-title":"Toxicol Appl Pharmacol"},{"key":"9194_CR41","unstructured":"OECD (2002) Hazard assessment of perfluorooctanesulfonate (PFOS) and its salts. Unclassified ENV\/JM\/RD(2002)17\/Final. Document No. JT00135607. Organisation for Economic Co-operation and Development, Paris"},{"key":"9194_CR42","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0300-483X(02)00573-5","volume":"184","author":"K Ohmori","year":"2003","unstructured":"Ohmori K, Kudo N, Katayama K, Kawashima Y (2003) Comparison of the toxicokinetics between perfluorocarboxylic acids with different carbon chain length. Toxicology 184:135\u2013140. doi: 10.1016\/S0300-483X(02)00573-5","journal-title":"Toxicology"},{"key":"9194_CR43","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1006\/taap.2001.9159","volume":"173","author":"T Panaretakis","year":"2001","unstructured":"Panaretakis T, Shabalina IG, Grand\u00e9r D, Shoshan MC, DePierre JW (2001) Reactive oxygen species and mitochondria mediate the induction of apoptosis in human hepatoma HepG2 cells by the rodent peroxisome proliferator and hepatocarcinogen, perfluorooctanoic acid. Toxicol Appl Pharm 173:56\u201364. doi: 10.1006\/taap.2001.9159","journal-title":"Toxicol Appl Pharm"},{"key":"9194_CR44","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/0014-4800(87)90011-6","volume":"47","author":"TP Pastoor","year":"1987","unstructured":"Pastoor TP, Lee KP, Perri MA, Gillies PJ (1987) Biochemical and morphological studies of ammonium perfluorooctanoate-induced hepatomegaly and peroxisome proliferation. Exp Mol Pathol 47:98\u2013109. doi: 10.1016\/0014-4800(87)90011-6","journal-title":"Exp Mol Pathol"},{"key":"9194_CR45","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0300-483X(02)00511-5","volume":"83","author":"AM Seacat","year":"2003","unstructured":"Seacat AM, Thomford PJ, Hansen KJ et al (2003) Sub-chronic dietary toxicity of potassium perfluorooctanesulfonate in rats. Toxicology 83:117\u2013131. doi: 10.1016\/S0300-483X(02)00511-5","journal-title":"Toxicology"},{"key":"9194_CR46","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1093\/toxsci\/kfg121","volume":"74","author":"JR Thibodeaux","year":"2003","unstructured":"Thibodeaux JR, Hanson RG, Rogers JM et al (2003) Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. I: Maternal and prenatal evaluations. Toxicol Sci 74:369\u2013381. doi: 10.1093\/toxsci\/kfg121","journal-title":"Toxicol Sci"},{"key":"9194_CR47","volume-title":"Draft risk assessment of the potential human health effects associated with exposure to perfluorooctanoic acid","author":"US EPA","year":"2005","unstructured":"US EPA (2005) Draft risk assessment of the potential human health effects associated with exposure to perfluorooctanoic acid. US Environmental Protection Agency, Washington, DC"},{"key":"9194_CR48","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1046\/j.1365-2249.2000.01367.x","volume":"122","author":"Q Yang","year":"2000","unstructured":"Yang Q, Xie Y, Depierre JW (2000) Effects of peroxisome proliferators on the thymus and spleen of mice. Clin Exp Immunol 122:219\u2013226. doi: 10.1046\/j.1365-2249.2000.01367.x","journal-title":"Clin Exp Immunol"},{"key":"9194_CR49","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/BF01702360","volume":"44","author":"M Ylinen","year":"1990","unstructured":"Ylinen M, Kojo A, Hanhij\u00e4rvi H, Peura P (1990) Disposition of perfluooctanoic acid in the rat after single and subchronic administration. Bull Environ Contam Toxicol 44:46\u201353. doi: 10.1007\/BF01702360","journal-title":"Bull Environ Contam Toxicol"},{"key":"9194_CR50","first-page":"969","volume":"35","author":"P Zhang","year":"2007","unstructured":"Zhang P, Shi YL, Cai YQ, Mou SF (2007) Determination of perfluorinated compounds in water samples by high performance liquid chromatography-electrospray tandem mass spectrometry. Chin J Anal Chem 35:969\u2013972","journal-title":"Chin J Anal Chem"}],"container-title":["Archives of Environmental Contamination and Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00244-008-9194-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00244-008-9194-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00244-008-9194-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T10:00:32Z","timestamp":1558692032000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00244-008-9194-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,26]]},"references-count":51,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["9194"],"URL":"https:\/\/doi.org\/10.1007\/s00244-008-9194-6","relation":{},"ISSN":["0090-4341","1432-0703"],"issn-type":[{"value":"0090-4341","type":"print"},{"value":"1432-0703","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,26]]}}}