{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T16:41:47Z","timestamp":1788799307322,"version":"build-2803163510"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2017,1,21]],"date-time":"2017-01-21T00:00:00Z","timestamp":1484956800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Cardiol"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1007\/s00246-016-1555-8","type":"journal-article","created":{"date-parts":[[2017,1,21]],"date-time":"2017-01-21T01:09:52Z","timestamp":1484960992000},"page":"608-616","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Measurement of Aortic Valve Coaptation and Effective Height Using Echocardiography in Patients with Ventricular Septal Defects and Aortic Valve Prolapse"],"prefix":"10.1007","volume":"38","author":[{"given":"Satoru","family":"Iwashima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Uchiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takamichi","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyohiro","family":"Takigiku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manatomo","family":"Toyono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nao","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Nii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,1,21]]},"reference":[{"key":"1555_CR1","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/S0002-9149(01)01517-X","volume":"87","author":"K Lun","year":"2001","unstructured":"Lun K, Li H, Leung MP, Chau AK, Yung T, Chiu CS et al (2001) Analysis of indications for surgical closure of subarterial ventricular septal defect without associated aortic cusp prolapse and aortic regurgitation. Am J Cardiol 87:1266","journal-title":"Am J Cardiol"},{"key":"1555_CR2","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1016\/0002-8703(84)90759-2","volume":"108","author":"K Momma","year":"1984","unstructured":"Momma K, Toyama K, Takao A, Ando M, Nakazawa M, Hirosawa K et al (1984) Natural history of subarterial infundibular ventricular septal defect. Am Heart J 108:1312\u20131317","journal-title":"Am Heart J"},{"key":"1555_CR3","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/0002-9149(87)91042-3","volume":"60","author":"MP Leung","year":"1987","unstructured":"Leung MP, Beerman LB, Siewers RD, Bahnson HT, Zuberbuhler JR (1987) Long-term follow-up after aortic valvuloplasty and defect closure in ventricular septal defect with aortic regurgitation. Am J Cardiol 60:890\u2013894","journal-title":"Am J Cardiol"},{"key":"1555_CR4","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1016\/S0002-9149(97)00105-7","volume":"79","author":"K Tohyama","year":"1997","unstructured":"Tohyama K, Satomi G, Momma K (1997) Aortic valve prolapse and aortic regurgitation associated with subpulmonic ventricular septal defect. Am J Cardiol 79:1285\u20131289","journal-title":"Am J Cardiol"},{"key":"1555_CR5","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1161\/01.CIR.48.5.1028","volume":"48","author":"K Tatsuno","year":"1973","unstructured":"Tatsuno K, Konno S, Ando M, Sakakibara S (1973) Pathogenic mechanism of prolapsing aortic valve and aortic regurgitation associated with ventricular septal defect: anatomical, angiographic and surgical consideration. Circulation 48:1028\u20131037","journal-title":"Circulation"},{"key":"1555_CR6","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1136\/hrt.43.3.332","volume":"43","author":"B Soto","year":"1980","unstructured":"Soto B, Becker AE, Moulaert AJ, Lie JT, Anderson RH (1980) Classification of ventricular septal defects. Br Heart J 43:332","journal-title":"Br Heart J"},{"key":"1555_CR7","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/BF02059966","volume":"2","author":"M Ando","year":"1986","unstructured":"Ando M, Takao A (1986) Pathological anatomy of ventricular septal defect associated with aortic valve prolapse and regurgitation. Heart Vessels 2:117","journal-title":"Heart Vessels"},{"key":"1555_CR8","doi-asserted-by":"crossref","unstructured":"Bierbach BO, Aicher D, Issa OA, Bomberg H, Gr\u00e4ber S, Glombitza P et al (2010) Aortic root and cusp configuration determine aortic valve function. Eur J Cardio-thoracic Surg 38:400\u2013406","DOI":"10.1016\/j.ejcts.2010.01.060"},{"key":"1555_CR9","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/0002-9149(89)90430-X","volume":"64","author":"MJ Roman","year":"1989","unstructured":"Roman MJ, Devereux RB, Kramer Fox R, O\u2019Loughlin J (1989) Two-dimensional echocardiographic aortic root dimensions in normal children and adults. Am J Cardiol 64:507\u2013512","journal-title":"Am J Cardiol"},{"key":"1555_CR10","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S0022-5223(94)70465-1","volume":"107","author":"KS Kunzelman","year":"1994","unstructured":"Kunzelman KS, Grande KJ, David TE, Cochran RP, Verrier ED (1994) Aortic root and valve relationships. Impact on surgical repair. J Thorac Cardiovasc Surg 107:162\u2013170","journal-title":"J Thorac Cardiovasc Surg"},{"key":"1555_CR11","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1046\/j.1475-097X.2003.00501.x","volume":"23","author":"T Poutanen","year":"2003","unstructured":"Poutanen T, Tikanoja T, Sairanen H, Jokinen E (2003) Normal aortic dimensions and flow in 168 children and young adults. Clin Physiol Funct Imaging 23:224\u2013229","journal-title":"Clin Physiol Funct Imaging"},{"key":"1555_CR12","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1161\/01.RES.35.6.871","volume":"35","author":"M Swanson","year":"1974","unstructured":"Swanson M, Clark RE (1974) Dimensions and geometric relationships of the human aortic valve as a function of pressure. Circ Res 35:871\u2013882","journal-title":"Circ Res"},{"key":"1555_CR13","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.jtcvs.2006.04.032","volume":"132","author":"HJ Sch\u00e4fers","year":"2006","unstructured":"Sch\u00e4fers HJ, Bierbach B, Aicher D (2006) A new approach to the assessment of aortic cusp geometry. J Thorac Cardiovasc Surg 132:436\u2013438","journal-title":"J Thorac Cardiovasc Surg"},{"key":"1555_CR14","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0894-7317(03)00335-3","volume":"16","author":"WA Zoghbi","year":"2003","unstructured":"Zoghbi WA, Enriquez-Sarano M, Foster E, Grayburn PA, Kraft CD, Levine RA, Nihoyannopoulos P et al (2003) Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and doppler echocardiography. J Am Soc Echocardiogr 16:777\u2013802","journal-title":"J Am Soc Echocardiogr"},{"key":"1555_CR15","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1016\/j.echo.2008.02.006","volume":"21","author":"MD Pettersen","year":"2008","unstructured":"Pettersen MD, Du W, Skeens ME, Humes RA (2008) Regression equations for calculation of Z scores of cardiac structures in a large cohort of healthy infants, children, and adolescents: an echocardiographic study. J Am Soc Echocardiogr 21:922\u2013934","journal-title":"J Am Soc Echocardiogr"},{"key":"1555_CR16","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/0002-8703(68)90321-9","volume":"175","author":"R Praagh Van","year":"1968","unstructured":"Van Praagh R, McNamara JJ (1968) Anatomic types of ventricular septal defect with aortic insufficiency. Diagnostic and surgical considerations. Am Heart J 175:604\u2013619","journal-title":"Am Heart J"},{"key":"1555_CR17","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0022-5223(97)70321-0","volume":"113","author":"MH Yacoub","year":"1997","unstructured":"Yacoub MH, Khan H, Stavri G, Shinebourne E, Radley-Smith R (1997) Anatomic correction of the syndrome of prolapsing right coronary aortic cusp, dilatation of the sinus of valsalva, and ventricular septal defect. J Thorac Cardiovasc Surg 113:253\u2013261","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"suppl III","key":"1555_CR18","first-page":"III40III46","volume":"78","author":"MR Leval de","year":"1998","unstructured":"de Leval MR, Pozzi M, Starnes V, Sullivan ID, Stark J, Somerville J et al (1998) Surgical management of doubly committed subarterial ventricular septal defects. Circulation 78(suppl III):III40\u2013III46","journal-title":"Circulation"},{"key":"1555_CR19","doi-asserted-by":"crossref","first-page":"800","DOI":"10.7326\/0003-4819-106-6-800","volume":"106","author":"MJ Roman","year":"1987","unstructured":"Roman MJ, Devereux RB, Niles NW, Hochreiter C, Kligfield P, Sato N et al (1987) Aortic root dilatation as a cause of isolated, severe aortic regurgitation. Prevalence, clinical and echocardiographic patterns, and relation to left ventricular hypertrophy and function. Ann Intern Med 106:800\u2013807","journal-title":"Ann Intern Med"},{"key":"1555_CR20","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1136\/hrt.54.2.179","volume":"54","author":"LM Shapiro","year":"1985","unstructured":"Shapiro LM, Thwaites B, Westgate C, Donaldson R (1985) Prevalence and clinical significance of aortic valve prolapse. Br Heart J 54:179\u2013183","journal-title":"Br Heart J"},{"key":"1555_CR21","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.ejcts.2005.09.012","volume":"28","author":"MJ Thubrikar","year":"2005","unstructured":"Thubrikar MJ, Labrosse MR, Zehr KJ, Robicsek F, Gong GG, Fowler BL (2005) Aortic root dilatation may alter the dimensions of the valve leaflets. Eur J Cardiothorac Surg 28:850\u2013855","journal-title":"Eur J Cardiothorac Surg"},{"key":"1555_CR22","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1067\/mtc.2001.114635","volume":"122","author":"F Langer","year":"2001","unstructured":"Langer F, Graeter T, Nikoloudakis N, Aicher D, Wendler O, Sch\u00e4fers HJ (2001) Valve-preserving aortic replacement: does the additional repair of leaflet prolapse adversely affect the results? J Thorac Cardiovasc Surg 122:270\u2013277","journal-title":"J Thorac Cardiovasc Surg"},{"key":"1555_CR23","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1007\/s00431-015-2575-8","volume":"174","author":"YA Zarate","year":"2015","unstructured":"Zarate YA, Sellars E, Lepard T, Carlo WF, Tang X, Collins RT II (2015) Aortic dilation in pediatric patients. Eur J Pediatr 174:1585\u20131592","journal-title":"Eur J Pediatr"},{"key":"1555_CR24","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0070-2153(04)62006-0","volume":"62","author":"CM Kelleher","year":"2004","unstructured":"Kelleher CM, McLean SE, Mecham RP (2004) Vascular extracellular matrix and aortic development. Curr Top Dev Biol 62:153\u2013188","journal-title":"Curr Top Dev Biol"},{"key":"1555_CR25","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/S0934-8832(11)80057-0","volume":"12","author":"WC Parks","year":"1992","unstructured":"Parks WC, Roby JD, Wu LC, Grosso LE (1992) Cellular expression of tropoelastin mRNA splice variants. Matrix 12:156\u2013162","journal-title":"Matrix"},{"key":"1555_CR26","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.ijcard.2004.03.023","volume":"101","author":"H Tomita","year":"2005","unstructured":"Tomita H, Arakaki Y, Ono Y, Yamada O, Yagihara T, Echigo S (2005) Impact of noncoronary cusp prolapse in addition to right coronary cusp prolapse in patients with a perimembranous ventricular septal defect. Int J Cardiol 101:279\u2013283","journal-title":"Int J Cardiol"},{"key":"1555_CR27","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/S0003-4975(97)00718-2","volume":"64","author":"H Komai","year":"1997","unstructured":"Komai H, Naito Y, Fujiwara K, Noguchi Y, Nishimura Y, Uemura S (1997) Surgical strategy for doubly committed subarterial ventricular septal defect with aortic cusp prolapse. Ann Thorac Surg 64:1146\u20131149","journal-title":"Ann Thorac Surg"},{"key":"1555_CR28","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0003-4975(91)91422-R","volume":"52","author":"JF Hitchcock","year":"1991","unstructured":"Hitchcock JF, Suijker WJL, Ksiezycka E, Harinck E, van Mill GJ, Ruzyllo W et al (1991) Management of ventricular septal defect with associated aortic incompetence. Ann Thorac Surg 52:70\u201373","journal-title":"Ann Thorac Surg"},{"key":"1555_CR29","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/S0002-9149(97)00690-5","volume":"80","author":"F Santini","year":"1997","unstructured":"Santini F, Mazzucco A (1997) Timing of surgical closure of subpulmonary ventricular septal defect in infancy. Am J Cardiol 80:976\u201397730","journal-title":"Am J Cardiol"},{"key":"1555_CR30","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/0003-4975(95)90006-3","volume":"56","author":"CL Backer","year":"1993","unstructured":"Backer CL, Winters RC, Zales VR, Takami H, Muster AJ, Benson DW Jr et al (1993) Restrictive ventricular septal defect: how small is too small to close? Ann Thorac Surg 56:1014\u20131019","journal-title":"Ann Thorac Surg"},{"key":"1555_CR31","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/S0735-1097(02)01706-0","volume":"39","author":"HM Gabriel","year":"2002","unstructured":"Gabriel HM, Heger M, Innerhofer P, Zehetgruber M, Mundigler G, Wimmer M et al (2002) Long-term outcome of patients with ventricular septal defect considered not to require surgical closure during childhood. J Am Coll Cardiol 39:1066\u20131071","journal-title":"J Am Coll Cardiol"},{"key":"1555_CR32","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1016\/j.jacc.2015.02.055","volume":"65","author":"ME Menting","year":"2015","unstructured":"Menting ME, Cuypers JA, Opi\u0107 P, Utens EM, Witsenburg M, van den Bosch AE et al (2015) The unnatural history of the ventricular septal defect: outcome up to 40\u2009years after surgical closure. J Am Coll Cardiol 65:1941\u20131951","journal-title":"J Am Coll Cardiol"},{"key":"1555_CR33","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.ahj.2006.10.025","volume":"153","author":"SN Chiu","year":"2007","unstructured":"Chiu SN, Wang JK, Lin MT, Chen CA, Chen HC, Chang CI et al (2007) Progression of aortic regurgitation after surgical repair of outlet-type ventricular septal defects. Am Heart J 153:336\u2013342","journal-title":"Am Heart J"},{"key":"1555_CR34","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S0003-4975(01)03393-8","volume":"73","author":"YF Cheung","year":"2002","unstructured":"Cheung YF, Chiu CS, Yung TC, Chau AK (2002) Impact of preoperative aortic cusp prolapse on long-term outcome after surgical closure of subarterial ventricular septal defect. Ann Thorac Surg 73:622\u2013627","journal-title":"Ann Thorac Surg"},{"key":"1555_CR35","first-page":"20","volume":"90","author":"JA Son van","year":"1994","unstructured":"van Son JA, Danielson GK, Schaff HV, Orszulak TA, Edwards WD, Seward JB (1994) Long-term outcome of surgical repair of ruptured sinus of Valsalva aneurysm. Circulation 90:20\u201329","journal-title":"Circulation"},{"key":"1555_CR36","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.jcmg.2009.04.013","volume":"2","author":"JB le Polain de Waroux","year":"2009","unstructured":"le Polain de Waroux JB, Pouleur AC, Robert A, Pasquet A, Gerber BL, Noirhomme P et al (2009) Mechanisms of recurrent aortic regurgitation after aortic valve repair: predictive value of intraoperative transesophageal echocardiography. JACC Cardiovasc Imaging 2:931\u2013939","journal-title":"JACC Cardiovasc Imaging"},{"key":"1555_CR37","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.athoracsur.2015.05.002","volume":"100","author":"KW Stern","year":"2015","unstructured":"Stern KW, White MT, Verghese GR, Del Nido PJ, Geva T (2015) Intraoperative echocardiography for congenital aortic valve repair: predictors of early reoperation. Ann Thorac Surg 100:678\u2013685","journal-title":"Ann Thorac Surg"}],"container-title":["Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-016-1555-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00246-016-1555-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-016-1555-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T08:46:20Z","timestamp":1601369180000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00246-016-1555-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,21]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["1555"],"URL":"https:\/\/doi.org\/10.1007\/s00246-016-1555-8","relation":{},"ISSN":["0172-0643","1432-1971"],"issn-type":[{"value":"0172-0643","type":"print"},{"value":"1432-1971","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,21]]}}}