{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T08:55:38Z","timestamp":1773219338659,"version":"3.50.1"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T00:00:00Z","timestamp":1571961600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T00:00:00Z","timestamp":1571961600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"This work was supported by an internal institutional grant","award":["grant No. 2017\/III\/33-MN)."],"award-info":[{"award-number":["grant No. 2017\/III\/33-MN)."]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Cardiol"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p>Neoaortic regurgitation and root dilatation are common findings in patients with transposition after an arterial switch operation. The aim of this study was to describe the relation between neoaortic regurgitation long term after an arterial switch procedure, aortic root diameters, and surgical technique used. We also assessed the agreement of the neoaortic regurgitation grade and root diameters in different imaging modalities. For this retrospective study, we qualified 56 consecutive patients who, according to our institutional protocol, had a routine postoperative evaluation of more than 16\u00a0years with multimodality imaging studies. Neoaortic regurgitation was assessed by both transthoracic echocardiography and magnetic resonance imaging, and the root diameters obtained by echocardiography and tomography were compared to the reference values and associated with the presence of neoaortic insufficiency. Neoaortic insufficiency was present in 75% of examined patients; the vast majority of them had trace or mild regurgitation, and its qualitative evaluation was significantly different between echocardiography and magnetic resonance imaging. In our study group, the neoaortic valve and aortic sinus were larger in relation to the normal values, and they were significantly correlated with the presence of neoaortic insufficiency, but not with the surgical technique used. Values obtained by echocardiography and tomography correlated well but were significantly different. Transthoracic echocardiography has a tendency to overestimate the severity of regurgitation compared to magnetic resonance imaging. Neoaortic valve and sinus dilatation are significantly correlated with valve insufficiency, but in most cases of root dilatation, the valve remains competent.<\/jats:p>","DOI":"10.1007\/s00246-019-02217-w","type":"journal-article","created":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T22:37:06Z","timestamp":1572043026000},"page":"31-37","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Neoaortic Regurgitation in Patients with Transposition Long Term After an Arterial Switch Operation and Its Relation to the Root Diameters and Surgical Technique Used"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9156-6648","authenticated-orcid":false,"given":"Krzysztof W.","family":"Michalak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarzyna","family":"Sobczak-Budlewska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacek J.","family":"Moll","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konrad","family":"Szymczyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jadwiga A.","family":"Moll","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"\u0141ubisz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej","family":"Moll","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,10,25]]},"reference":[{"key":"2217_CR1","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1016\/j.jacc.2014.06.1150","volume":"64","author":"J Villafa\u00f1e","year":"2014","unstructured":"Villafa\u00f1e J, Lantin-Hermoso MR, Bhatt AB, Tweddel JS, Geva T, Nathan M et al (2014) D-transposition of the great arteries: the current era of the arterial switch operation. J Am Coll Cardiol 64:498\u2013511","journal-title":"J Am Coll Cardiol"},{"key":"2217_CR2","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1093\/ejcts\/ezs709","volume":"43","author":"KW Michalak","year":"2013","unstructured":"Michalak KW, Moll JA, Moll M, Dryzek P, Moszura T, Kopala M et al (2013) The neoaortic root in children with transposition of the great arteries after an arterial switch operation. Eur J Cardiothorac Surg 43:1101\u20131108","journal-title":"Eur J Cardiothorac Surg"},{"key":"2217_CR3","doi-asserted-by":"publisher","first-page":"2057","DOI":"10.1016\/j.jacc.2005.12.061","volume":"47","author":"J Losay","year":"2006","unstructured":"Losay J, Touchot A, Capderou A, Piot JD, Belli E, Planch\u00e9 C et al (2006) Aortic valve regurgitation after arterial switch operation for transposition of the great arteries: incidence, risk factors, and outcome. J Am Coll Cardiol 47:2057\u20132062","journal-title":"J Am Coll Cardiol"},{"key":"2217_CR4","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1016\/S0022-5223(03)00971-1","volume":"126","author":"S Lalezari","year":"2003","unstructured":"Lalezari S, Hazekamp MG, Bartelings MM, Schoof PH, Gittenberger-De Groot AC (2003) Pulmonary artery remodeling in transposition of the great arteries: relevance for neoaortic root dilatation. J Thorac Cardiovasc Surg 126:1053\u20131060","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2217_CR5","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1007\/s00246-017-1761-z","volume":"39","author":"K Szymczyk","year":"2018","unstructured":"Szymczyk K, Moll M, Sobczak-Budlewska K, Moll JA, Stefa\u0144czyk L, Grzelak P et al (2018) Usefulness of routine coronary CT angiography in patients with transposition of the great arteries after an arterial switch operation. Pediatr Cardiol 39:335\u2013346","journal-title":"Pediatr Cardiol"},{"key":"2217_CR6","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.athoracsur.2011.09.044","volume":"93","author":"JJ Moll","year":"2012","unstructured":"Moll JJ, Michalak KW, M\u0142udzik K, Moszura T, Kopala M, Moll M et al (2012) Long-term outcome of direct neopulmonary artery reconstruction during the arterial switch procedure. Ann Thorac Surg 93:177\u2013184","journal-title":"Ann Thorac Surg"},{"key":"2217_CR7","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1093\/ehjci\/jev014","volume":"16","author":"RM Lang","year":"2015","unstructured":"Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L et al (2015) Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 16:233\u2013270","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2217_CR8","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1016\/j.echo.2008.02.006","volume":"21","author":"MD Pettersen","year":"2008","unstructured":"Pettersen MD, Du W, Skeens ME, Humes RA (2008) Regression equations for calculation of z scores of cardiac structures in a large cohort of healthy infants, children, and adolescents: an echocardiographic study. J Am Soc Echocardiogr 21:922\u2013934","journal-title":"J Am Soc Echocardiogr"},{"key":"2217_CR9","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1148\/radiol.14140500","volume":"274","author":"SV Hegde","year":"2015","unstructured":"Hegde SV, Lensing SY, Greenberg SB (2015) Determining the normal aorta size in children. Radiology 274:859\u2013865","journal-title":"Radiology"},{"key":"2217_CR10","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/s12968-015-0134-0","volume":"17","author":"G Crouch","year":"2015","unstructured":"Crouch G, Tully PJ, Bennetts J, Sinhal A, Bradbrook C, Penhall AL et al (2015) Quantitative assessment of paravalvular regurgitation following transcatheter aortic valve replacement. J Cardiovasc Magn Reson 17:32","journal-title":"J Cardiovasc Magn Reson"},{"key":"2217_CR11","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1016\/S0003-4975(99)00698-0","volume":"68","author":"K Furukawa","year":"1999","unstructured":"Furukawa K, Ohteki H, Cao Z, Doi K, Narita Y, Minato N (1999) Does dilatation of the sinotubular junction cause aortic regurgitation? Ann Thorac Surg 68:949\u2013954","journal-title":"Ann Thorac Surg"},{"key":"2217_CR12","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1093\/ejcts\/ezs264","volume":"43","author":"HG Lim","year":"2013","unstructured":"Lim HG, Kim WH, Lee JR, Kim YJ (2013) Long-term results of the arterial switch operation for ventriculo-arterial discordance. Eur J Cardiothorac Surg 43:325\u2013334","journal-title":"Eur J Cardiothorac Surg"},{"key":"2217_CR13","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.1016\/S0022-5223(03)01325-4","volume":"126","author":"R Formigari","year":"2003","unstructured":"Formigari R, Toscano A, Giardini A, Gargiulo G, Di Donato R, Picchio FM et al (2003) Prevalence and predictors of neoaortic regurgitation after arterial switch operation for transposition of the great arteries. J Thorac Cardiovasc Surg 126:1753\u20131759","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2217_CR14","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1093\/ejcts\/ezw360","volume":"51","author":"GE Sarris","year":"2017","unstructured":"Sarris GE, Balmer C, Bonou P, Comas JV, da Cruz E, Chiara LD et al (2017) Clinical guidelines for the management of patients with transposition of the great arteries with intact ventricular septum. Eur J Cardiothorac Surg 51:e1\u2013e32","journal-title":"Eur J Cardiothorac Surg"}],"container-title":["Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-019-02217-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00246-019-02217-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-019-02217-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T23:49:48Z","timestamp":1603496988000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00246-019-02217-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,25]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["2217"],"URL":"https:\/\/doi.org\/10.1007\/s00246-019-02217-w","relation":{},"ISSN":["0172-0643","1432-1971"],"issn-type":[{"value":"0172-0643","type":"print"},{"value":"1432-1971","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,25]]},"assertion":[{"value":"16 July 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 October 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 October 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The author declare that they have no competing interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}