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In this retrospective study, we included 65 fetuses with a prenatally suspected, isolated CoA, born 2010\u20132018. Dimensions of the cardiac structures, aortic, and ductal arches expressed as ratios and Z-scores were analyzed in relation to outcome. Fetuses that developed CoA postnatally (34%) exhibited significantly smaller Z-scores of left cardiac structures from the mitral valve to the aortic isthmus. The most sensitive and specific predictors were a carotid-subclavian artery index (CSAI) of\u2009&lt;\u20090.78 (92.3% sensitivity, 96.8% specificity) or a product of isthmus-to-duct ratio in the three-vessel trachea view (3VT) and the mitral-to-tricuspid valve ratio (I\/D<jats:sub>3VT<\/jats:sub>xMV\/TV) of\u2009&lt;\u20090.37 (100% sensitivity, 94.6% specificity). When comparing different Z-score datasets, we observed large and highly significant differences. Postnatal CoA can be predicted with high accuracy during fetal life using CSAI or I\/D<jats:sub>3VT<\/jats:sub>xMV\/TV. The latter may be particularly useful if adequate sagittal aortic arch images cannot be obtained. As significant and clinically unacceptable differences in Z-scores were observed for the same measurements, this calls for a large multi-center collaboration to generate reliable fetal echocardiographic Z-scores.<\/jats:p>","DOI":"10.1007\/s00246-020-02509-6","type":"journal-article","created":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T13:03:26Z","timestamp":1608728606000},"page":"517-525","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Fetal Echocardiographic Dimension Indices: Important Predictors of Postnatal Coarctation"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0879-6499","authenticated-orcid":false,"given":"Katrin","family":"Fricke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petru","family":"Liuba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constance G.","family":"Weismann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,12,23]]},"reference":[{"key":"2509_CR1","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1136\/hrt.2004.057182","volume":"91","author":"E Rosenthal","year":"2005","unstructured":"Rosenthal E (2005) Coarctation of the aorta from fetus to adult: curable condition or life long disease process? 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