{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T08:55:48Z","timestamp":1765356948432,"version":"3.37.3"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2021,6,9]],"date-time":"2021-06-09T00:00:00Z","timestamp":1623196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,6,9]],"date-time":"2021-06-09T00:00:00Z","timestamp":1623196800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"the Biomedical and Engineering (Science) Interdisciplinary Study Fund of Shanghai Jiaotong University","award":["YG2019QNA04"],"award-info":[{"award-number":["YG2019QNA04"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Cardiol"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1007\/s00246-021-02646-6","type":"journal-article","created":{"date-parts":[[2021,6,9]],"date-time":"2021-06-09T11:06:28Z","timestamp":1623236788000},"page":"1601-1606","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Elevated Arterial\u2013Central Venous Carbon Dioxide Partial Pressure Difference Indicates Poor Prognosis in the Early Postoperative Period of Open Heart Surgery in Infants with Congenital Heart Disease"],"prefix":"10.1007","volume":"42","author":[{"given":"Xiaolei","family":"Gong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9294-6458","authenticated-orcid":false,"given":"Limin","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujie","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunxiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingjie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haibo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinghao","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuoming","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,6,9]]},"reference":[{"key":"2646_CR1","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1097\/EJA.0000000000000064","volume":"31","author":"J Mallat","year":"2014","unstructured":"Mallat J, Pepy F, Lemyze M, Gasan G, Vangrunderbeeck N, Tronchon L, Vallet B, Thevenin D (2014) Central venous-to-arterial carbon dioxide partial pressure difference in early resuscitation from septic shock: a prospective observational study. Eur J Anaesthesiol 31:371\u2013380","journal-title":"Eur J Anaesthesiol"},{"key":"2646_CR2","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1097\/00003246-199110000-00009","volume":"19","author":"CK Mahutte","year":"1991","unstructured":"Mahutte CK, Jaffe MB, Sassoon CS, Wong DH (1991) Cardiac output from carbon dioxide production and arterial and venous oximetry. Crit Care Med 19:1270\u20131277","journal-title":"Crit Care Med"},{"key":"2646_CR3","first-page":"23","volume-title":"The Regulation of Tissue Oxygenation","author":"RN Pittman","year":"2016","unstructured":"Pittman RN (2016) The Regulation of Tissue Oxygenation, 2nd edn. Morgan & Claypool Life Sciences, San Rafael, CA, pp 23\u201336","edition":"2"},{"key":"2646_CR4","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1177\/0310057X1504300512","volume":"43","author":"BI Silbert","year":"2015","unstructured":"Silbert BI, Litton E, Ho KM (2015) Central venous-to-arterial carbon dioxide gradient as a marker of occult tissue hypoperfusion after major surgery. Anaesth Intensive Care 43:628\u2013634","journal-title":"Anaesth Intensive Care"},{"key":"2646_CR5","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1186\/s13054-015-0917-6","volume":"19","author":"E Robin","year":"2015","unstructured":"Robin E, Futier E, Pires O, Fleyfel M, Tavernier B, Lebuffe G, Vallet B (2015) Central venous-to-arterial carbon dioxide difference as a prognostic tool in high-risk surgical patients. Crit Care 19:227","journal-title":"Crit Care"},{"key":"2646_CR6","doi-asserted-by":"publisher","first-page":"1726","DOI":"10.1056\/NEJMra1208943","volume":"369","author":"JV Vincent","year":"2013","unstructured":"Vincent JV, De Backer D (2013) Circulatory shock. N Engl J Med 369:1726\u20131734","journal-title":"N Engl J Med"},{"key":"2646_CR7","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1002\/clc.22564","volume":"39","author":"HS Lim","year":"2016","unstructured":"Lim HS (2016) Cardiogenic Shock: Failure of oxygen delivery and oxygen utilization. Clin Cardiol 39:477\u2013483","journal-title":"Clin Cardiol"},{"key":"2646_CR8","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1097\/00003246-199105000-00006","volume":"19","author":"SM Cain","year":"1991","unstructured":"Cain SM, Curtis SE (1991) Experimental models of pathologic oxygen supply dependency. Crit Care Med 19:603\u2013612","journal-title":"Crit Care Med"},{"key":"2646_CR9","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1007\/s00134-005-2602-8","volume":"31","author":"J Cuschieri","year":"2005","unstructured":"Cuschieri J, Rivers EP, Donnino MW, Katilius M, Jacobsen G, Nguyen HB, Pamukov N, Horst HM (2005) Central venous\u2013arterial carbon dioxide difference as an indicator of cardiac index. Intensive Care Med 31:818\u2013822","journal-title":"Intensive Care Med"},{"key":"2646_CR10","doi-asserted-by":"publisher","first-page":"R294","DOI":"10.1186\/cc13160","volume":"17","author":"GA Ospina-Tasc\u00f3n","year":"2013","unstructured":"Ospina-Tasc\u00f3n GA, Bautista-Rinc\u00f3n DF, Uma\u00f1a M, Tafur JD, Guti\u00e9rrez A, Garc\u00eda AF, Berm\u00fadez W, Granados M, Arango-D\u00e1vila C, Hern\u00e1ndez G (2013) Persistently high venous-to-arterial carbon dioxide differences during early resuscitationare associated with poor outcomes in septic shock. Crit Care 17:R294","journal-title":"Crit Care"},{"key":"2646_CR11","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1097\/MCC.0000000000000493","volume":"24","author":"TWL Scheeren","year":"2018","unstructured":"Scheeren TWL, Wicke JN, Teboul J-L (2018) Understanding the carbon dioxide gaps. Curr Opin Crit Care 24:181\u2013189","journal-title":"Curr Opin Crit Care"},{"key":"2646_CR12","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1007\/s00134-013-2888-x","volume":"39","author":"PA van Beest","year":"2013","unstructured":"van Beest PA, Lont MC, Holman ND (2013) Central venous\u2013arterial pCO2 difference as a tool in resuscitation of sevptic patients. Intensive Care Med 39:1034\u20131039","journal-title":"Intensive Care Med"},{"key":"2646_CR13","doi-asserted-by":"publisher","first-page":"1110.e1","DOI":"10.1016\/j.jcrc.2013.07.049","volume":"28","author":"W Du","year":"2013","unstructured":"Du W, Liu DW, Wang XT, Long Y, Chai WZ, Zhou X, Rui X (2013) Combining central venous-to-arterial partial pressure of carbon dioxide difference and central venous oxygen saturation to guide resuscitation in septic shock. J Crit Care 28:1110.e1-1110.e5","journal-title":"J Crit Care"},{"key":"2646_CR14","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1177\/021849230501300314","volume":"13","author":"Y Takami","year":"2005","unstructured":"Takami Y, Masumoto H (2005) Mixed venous-arterial CO2 tension gradient after cardiopulmonary bypass. Asian Cardiovasc Thorac Annals 13:255\u2013260","journal-title":"Asian Cardiovasc Thorac Annals"},{"key":"2646_CR15","doi-asserted-by":"publisher","first-page":"1190","DOI":"10.1053\/j.jvca.2017.02.015","volume":"31","author":"PG Guinot","year":"2017","unstructured":"Guinot PG, Badoux L, Bernard E, Abou-Arab O, Lorne E, Dupont H (2017) Central venous-to-arterial carbon dioxide partial pressure difference in patients undergoing cardiac surgery is not related to postoperative outcomes. J Cardiothorac Vasc Anesth 31:1190\u20131196","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2646_CR16","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1097\/PCC.0000000000001085","volume":"18","author":"LA Rhodes","year":"2017","unstructured":"Rhodes LA, Erwin WC, Borasino S, Cleveland DC, Alten JA (2017) Central venous to arterial CO2 difference after cardiac surgery in infants and neonates. Pediatr Crit Care Med 18:228\u2013233","journal-title":"Pediatr Crit Care Med"},{"key":"2646_CR17","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1097\/PCC.0000000000001229","volume":"18","author":"T Akamatsu","year":"2017","unstructured":"Akamatsu T, Inata Y, Tachibana K, Hatachi T, Takeuchi M (2017) Elevated central venous to arterial CO2 difference is not associated with poor clinical outcomes after cardiac surgery with cardiopulmonary bypass in children. Pediatr Crit Care Med 18:859\u2013862","journal-title":"Pediatr Crit Care Med"}],"container-title":["Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-021-02646-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00246-021-02646-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-021-02646-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T20:12:29Z","timestamp":1632514349000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00246-021-02646-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,9]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["2646"],"URL":"https:\/\/doi.org\/10.1007\/s00246-021-02646-6","relation":{},"ISSN":["0172-0643","1432-1971"],"issn-type":[{"type":"print","value":"0172-0643"},{"type":"electronic","value":"1432-1971"}],"subject":[],"published":{"date-parts":[[2021,6,9]]},"assertion":[{"value":"22 February 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 June 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}