{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T04:24:35Z","timestamp":1787372675994,"version":"build-2736575974"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T00:00:00Z","timestamp":1637280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T00:00:00Z","timestamp":1637280000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Cardiol"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1007\/s00246-021-02777-w","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T08:02:50Z","timestamp":1637308970000},"page":"719-725","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Early Presentation of Patients with Abnormal Origin of Left Coronary Artery from the Pulmonary Artery is a Predictor of Poor Mid-term Outcomes"],"prefix":"10.1007","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4000-4287","authenticated-orcid":false,"given":"Fedoua","family":"El-Louali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marien","family":"Lenoir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9lia","family":"Gran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chlo\u00e9","family":"Allary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Fouilloux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Ovaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,11,19]]},"reference":[{"key":"2777_CR1","first-page":"328","volume":"204","author":"J Pfannschmidt","year":"1992","unstructured":"Pfannschmidt J, Ruskowski H, de Vivie ER (1992) BlandWhite-Garland syndrome: clinical aspects, diagnosis, therapy [in German]. KlinPadiatr 204:328\u2013334","journal-title":"KlinPadiatr"},{"key":"2777_CR2","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1161\/01.CIR.38.2.403","volume":"38","author":"H Wesselhoeft","year":"1968","unstructured":"Wesselhoeft H, Fawcett JS, Johnson AL (1968) Anomalous origin of the left coronary artery from the pulmonary trunk: its clinical spectrum, pathology, andpathophysiology, based on a review of 140 cases with seven further cases. Circulation 38:403\u2013425","journal-title":"Circulation"},{"key":"2777_CR3","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1148\/rg.292085059","volume":"29","author":"E Pe\u00f1a","year":"2009","unstructured":"Pe\u00f1a E, Nguyen ET, Merchant N, Dennie C (2009) ALCAPA syndrome: not just a pediatric disease. Radiographics 29:553\u2013565","journal-title":"Radiographics"},{"key":"2777_CR4","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/S0022-5223(19)42879-1","volume":"56","author":"BW Meyer","year":"1968","unstructured":"Meyer BW, Steanik G, Stiles QR, Lindesmith GG, Jones JC (1968) A method of definitive surgical treatment of anomalous origin of the left coronary artery. A case report. J Thorac Cardiovasc Surg 56:104\u2013107","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2777_CR5","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/S0022-5223(19)38154-1","volume":"78","author":"S Takeuchi","year":"1979","unstructured":"Takeuchi S, Imamura H, Katsumoto K, Hayashi I, Katohgi T, Yozu R et al (1979) New surgical method for repair of anomalous left coronary artery from pulmonary artery. J Thorac Cardiovasc Surg 78:7\u201311","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2777_CR6","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1161\/01.CIR.50.3.582","volume":"50","author":"WH Neches","year":"1974","unstructured":"Neches WH, Mathews RA, Park SC, Lenox CC, Zuberbuhler JR, Siewers RD et al (1974) Anomalous origin of the left coronary artery from the pulmonary artery. A new method of surgical repair. Circulation 50:582\u2013587","journal-title":"Circulation"},{"key":"2777_CR7","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1016\/S0022-5223(19)34868-8","volume":"103","author":"CL Backer","year":"1992","unstructured":"Backer CL, Stout MJ, Zales VR, Muster AJ, Weigel TJ, Idriss FS et al (1992) Anomalous origin of the left coronary artery: a twenty-year review of surgical management. J Thorac Cardiovasc Surg 103:1049\u20131058","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2777_CR8","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/S0022-5223(19)36481-5","volume":"93","author":"R Bunton","year":"1987","unstructured":"Bunton R, Jonas RA, Lang P, Rein AJJT, Castaneda AR (1987) Anomalous origin of left coronary artery from pulmonary artery: ligation versus establishment of a two coronary artery system. J Thorac Cardiovasc Surg 93:103\u2013108","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2777_CR9","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1093\/oxfordjournals.eurheartj.a060626","volume":"15","author":"Z Jin","year":"1994","unstructured":"Jin Z, Berger F, Uhlemann F, Schroder C, Hetzer R, Alexi-Meskhishvili V et al (1994) Improvement in left ventricular dysfunction after aortic reimplantation in 11 consecutive paediatric patients with anomalous origin of the left coronary artery from the pulmonary artery: early results of a serial echocardiographic follow-up. Eur Heart J 15:1044\u20131049","journal-title":"Eur Heart J"},{"issue":"9 Suppl","key":"2777_CR10","first-page":"1138","volume":"94","author":"V Lambert","year":"1996","unstructured":"Lambert V, Touchot A, Losay J, Piot JD, Henglein D, Serraf A et al (1996) Midterm results after surgical repair of the anomalous origin of the coronary artery. Circulation 94(9 Suppl):1138\u20131143","journal-title":"Circulation"},{"key":"2777_CR11","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1016\/j.athoracsur.2006.11.005","volume":"83","author":"R Lange","year":"2007","unstructured":"Lange R, Vogt M, Horer J, Cleuziou J, Menzel A, Holper K et al (2007) Long-term results of repair of anomalous origin of the left coronary artery from the pulmonary artery. Ann Thorac Surg 83:1463\u20131471","journal-title":"Ann Thorac Surg"},{"key":"2777_CR12","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/S0022-5223(99)70431-9","volume":"117","author":"AD Cochrane","year":"1999","unstructured":"Cochrane AD, Coleman DM, Davis AM, Brizard CP, Wolfe R, Karl TR (1999) Excellent longterm functional outcome after an operation for anomalous left coronary artery from the pulmonary artery. J Thorac Cardiovasc Surg 117:332\u2013342","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2777_CR13","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1016\/S0735-1097(97)00175-7","volume":"30","author":"ML Schwartz","year":"1997","unstructured":"Schwartz ML, Jonas RA, Colan SD (1997) Anomalous origin of left coronary artery from pulmonary artery: recovery of left ventricular function after dual coronary repair. J Am Coll Cardiol 30:547\u2013553","journal-title":"J Am Coll Cardiol"},{"key":"2777_CR14","doi-asserted-by":"publisher","first-page":"1535","DOI":"10.1016\/S0003-4975(02)04822-1","volume":"75","author":"A Azakie","year":"2003","unstructured":"Azakie A, Russell JL, McCrindle BW, Van Arsdell GS, Benson LN, Coles JG et al (2003) Anatomic repair of anomalous left coronary artery from the pulmonary artery by aortic reimplantation: early survival, patterns of ventricular recovery and late outcome. Ann Thorac Surg 75:1535\u20131541","journal-title":"Ann Thorac Surg"},{"key":"2777_CR15","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1016\/S0003-4975(03)00344-8","volume":"76","author":"G Michielon","year":"2003","unstructured":"Michielon G, Di Carlo D, Brancaccio G, Guccione P, Mazzera E, Toscano A et al (2003) Anomalous coronary artery from the pulmonary artery: correlation between surgical timing and left ventricular function recovery. Ann Thorac Surg 76:581\u2013588","journal-title":"Ann Thorac Surg"},{"key":"2777_CR16","doi-asserted-by":"publisher","first-page":"1985","DOI":"10.1016\/S0003-4975(01)02518-8","volume":"71","author":"CB Huddleston","year":"2001","unstructured":"Huddleston CB, Balzer DT, Mendeloff EN (2001) Repair of anomalous left main coronary artery arising from the pulmonary artery in infants: long-term impact on the mitral valve. Ann Thorac Surg 71:1985\u20131989","journal-title":"Ann Thorac Surg"},{"key":"2777_CR17","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1067\/mtc.2001.112834","volume":"121","author":"Y Isomatsu","year":"2001","unstructured":"Isomatsu Y, Imai Y, Shin\u2019oka T, Aoki M, Iwata Y (2001) Surgical intervention for anomalous origin of the left coronary artery from the pulmonary artery: the Tokyo experience. J Thorac Cardiovasc Surg 121:792\u2013797","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2777_CR18","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/j.athoracsur.2007.03.036","volume":"84","author":"J Caspi","year":"2007","unstructured":"Caspi J, Pettitt TW, Sperrazza C, Mulder T, Stopa A (2007) Reimplantation of anomalous left coronary artery from the pulmonary artery without mitral valve repair. Ann Thorac Surg 84:619\u2013623","journal-title":"Ann Thorac Surg"},{"issue":"3","key":"2777_CR19","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1016\/S0022-5223(19)34739-7","volume":"104","author":"U Sauer","year":"1992","unstructured":"Sauer U, Stern H, Meisner H, Buhlmeyer K, Sebening F (1992) Risk factors for perioperative mortality in children with anomalous origin of the left coronary artery from the pulmonary artery. J Thorac Cardiovasc Surg 104(3):696\u2013705","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2777_CR20","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1016\/j.ejcts.2009.03.014","volume":"36","author":"W Ben Ali","year":"2009","unstructured":"Ben Ali W, Metton O, Roubertie F, Pouard P, Sidi D, Raisky O et al (2009) Anomalous origin of the left coronary artery from the pulmonary artery: late results with special attention to the mitral valve. Eur J Cardiothorac Surg 36:244\u2013249","journal-title":"Eur J Cardiothorac Surg"},{"key":"2777_CR21","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1016\/j.jtcvs.2011.04.006","volume":"142","author":"V Alexi-Meskishvili","year":"2011","unstructured":"Alexi-Meskishvili V, Nasseri BA, Nordmeyer S, Schmitt B, Weng YG, Bottcher W et al (2011) Repair of anomalous origin of the left coronary artery from the pulmonary artery in infants and children. J Thorac Cardiovasc Surg 142:868\u2013874","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2777_CR22","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1053\/tc.2000.6516","volume":"3","author":"CL Backer","year":"2000","unstructured":"Backer CL, Hillman N, Dodge-Khatami A, Mavroudis C (2000) Anomalous origin of the left coronary artery from the pulmonary artery: successful surgical strategy without assist devices. Semin Thorac Cardiovasc Surg 3:165\u2013172","journal-title":"Semin Thorac Cardiovasc Surg"},{"key":"2777_CR23","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.athoracsur.2008.03.032","volume":"86","author":"B Alsoufi","year":"2008","unstructured":"Alsoufi B, Sallehuddin A, Bulbul Z, Joufan M, Khouqeer F, Canver CC et al (2008) Surgical strategy to establish a dual-coronary system for the management of anomalous left coronary artery origin from the pulmonary artery. Ann Thorac Surg 86:170\u2013176","journal-title":"Ann Thorac Surg"},{"issue":"2","key":"2777_CR24","first-page":"57","volume":"8","author":"T Muzaffar","year":"2014","unstructured":"Muzaffar T, Ganie FA, GpoalSwamy S, Wani N (2014) The surgical outcome of anomalous origin of the left coronary artery from the pulmonary artery. Int Cardiovasc Res J 8(2):57\u201360","journal-title":"Int Cardiovasc Res J"},{"issue":"6","key":"2777_CR25","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1093\/icvts\/ivt061","volume":"16","author":"PA Kazmierczak","year":"2013","unstructured":"Kazmierczak PA, Ostrowska K, Dryzek P, Moll JA, Moll JJ (2013) Repair of anomalous origin of the left coronary artery from the pulmonary artery in infants. Interact Cardiovasc Thorac Surg 16(6):797\u2013801","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"2777_CR26","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1093\/ejcts\/ezx407","volume":"53","author":"R Lange","year":"2018","unstructured":"Lange R, Cleuziou J, Krane M, Ewert E, Pabst von Ohain J, Beran E et al (2018) Long-term outcome after anomalous left coronary artery from the pulmonary artery repair: a 40-year single-centre experience. Eur J Cardiothorac Surg 53:732\u2013739","journal-title":"Eur J Cardiothorac Surg"},{"key":"2777_CR27","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/1749-8090-3-33","volume":"3","author":"T Kristensen","year":"2008","unstructured":"Kristensen T, Kofoed KF, Helqvist S, Helvind M, Sondergaard L (2008) Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) presenting with ventricular fibrillation in an adult: a case report. J Cardiothorac Surg 3:33","journal-title":"J Cardiothorac Surg"},{"issue":"2","key":"2777_CR28","first-page":"140","volume":"8","author":"I Michel-Behnke","year":"2019","unstructured":"Michel-Behnke I, Pavo I, Recla S, Khalil M, Jux C, Schranz D (2019) Regenerative therapies in young hearts with structural or congenital heart disease. TranslPediatr 8(2):140\u2013150","journal-title":"TranslPediatr"}],"container-title":["Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-021-02777-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00246-021-02777-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-021-02777-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T13:05:04Z","timestamp":1649768704000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00246-021-02777-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,19]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["2777"],"URL":"https:\/\/doi.org\/10.1007\/s00246-021-02777-w","relation":{},"ISSN":["0172-0643","1432-1971"],"issn-type":[{"value":"0172-0643","type":"print"},{"value":"1432-1971","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,19]]},"assertion":[{"value":"30 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 November 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 November 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}