{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T20:30:23Z","timestamp":1791923423142,"version":"4.3.4"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Cardiol"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1007\/s00246-023-03308-5","type":"journal-article","created":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T19:02:57Z","timestamp":1696878177000},"page":"55-62","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Outcomes and Associated Extracardiac Malformations in Neonates from Colombia with Severe Congenital Heart Disease"],"prefix":"10.1007","volume":"45","author":[{"given":"Jorge L.","family":"Alvarado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anderson","family":"Bermon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Florez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Franco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilo","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy","family":"Villegas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nisha","family":"Shabbir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison Goetsch","family":"Weisman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn N.","family":"Weaver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos E.","family":"Prada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,10,9]]},"reference":[{"issue":"6","key":"3308_CR1","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1161\/CIRCRESAHA.116.309302","volume":"120","author":"BJ Bouma","year":"2017","unstructured":"Bouma BJ, Mulder BJ (2017) Changing landscape of congenital heart disease. Circ Res 120(6):908\u2013922","journal-title":"Circ Res"},{"issue":"25","key":"3308_CR2","doi-asserted-by":"publisher","first-page":"2716","DOI":"10.1161\/CIRCULATIONAHA.116.023544","volume":"133","author":"JK Triedman","year":"2016","unstructured":"Triedman JK, Newburger JW (2016) Trends in congenital heart disease: the next decade. Circulation 133(25):2716\u20132733","journal-title":"Circulation"},{"issue":"23","key":"3308_CR3","doi-asserted-by":"publisher","first-page":"e20593","DOI":"10.1097\/MD.0000000000020593","volume":"99","author":"W Wu","year":"2020","unstructured":"Wu W, He J, Shao X (2020) Incidence and mortality trend of congenital heart disease at the global, regional, and national level, 1990\u20132017. Medicine (Baltimore) 99(23):e20593","journal-title":"Medicine (Baltimore)"},{"key":"3308_CR4","doi-asserted-by":"publisher","first-page":"148","DOI":"10.7705\/biomedica.v38i0.3381","volume":"38","author":"S Tassinari","year":"2018","unstructured":"Tassinari S et al (2018) Epidemiology of congenital heart diseases in Bogota, Colombia, from 2001 to 2014: Improved surveillance or increased prevalence? Biomedica 38:148\u2013155","journal-title":"Biomedica"},{"issue":"7","key":"3308_CR5","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1590\/1806-9282.66.7.931","volume":"66","author":"JVB Cabral","year":"2020","unstructured":"Cabral JVB et al (2020) Mortality due to congenital heart disease in Pernambuco from 1996 to 2016. Rev Assoc Med Bras (1992) 66(7):931\u2013936","journal-title":"Rev Assoc Med Bras (1992)"},{"issue":"4","key":"3308_CR6","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1016\/j.clp.2014.08.002","volume":"41","author":"NE St Clair","year":"2014","unstructured":"St Clair NE et al (2014) Global challenges, efforts, and controversies in neonatal care. Clin Perinatol 41(4):749\u2013772","journal-title":"Clin Perinatol"},{"issue":"2","key":"3308_CR7","first-page":"161","volume":"24","author":"ACM Garc\u00eda","year":"2017","unstructured":"Garc\u00eda ACM, Moreno K, Sandoval N, Ronderos M, Dennis R (2017) Diferencias regionales en cardiopat\u00edas cong\u00e9nitas. Rev Colomb Cardiol 24(2):161\u2013168","journal-title":"Rev Colomb Cardiol"},{"issue":"2","key":"3308_CR8","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.cjco.2021.09.024","volume":"4","author":"K Ho","year":"2022","unstructured":"Ho K et al (2022) Trends in patient characteristic, cost, and mortality among mechanically ventilated adult patients with congenital heart disease in the United States. CJC Open 4(2):197\u2013205","journal-title":"CJC Open"},{"issue":"1","key":"3308_CR9","first-page":"e1","volume":"22","author":"N Sandoval","year":"2015","unstructured":"Sandoval N (2015) Congenital heart disease in colombia and worldwide\/Cardiopatias cong\u00e9nitas en Colombia y en el mundo. Rev Colomb Cardiol 22(1):e1\u2013e2","journal-title":"Rev Colomb Cardiol"},{"issue":"2","key":"3308_CR10","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1590\/S0103-05822013000200017","volume":"31","author":"RC Rosa","year":"2013","unstructured":"Rosa RC et al (2013) Congenital heart defects and extracardiac malformations. Rev Paul Pediatr 31(2):243\u2013251","journal-title":"Rev Paul Pediatr"},{"issue":"2","key":"3308_CR11","doi-asserted-by":"publisher","first-page":"86","DOI":"10.4103\/0974-2069.132474","volume":"7","author":"A Egbe","year":"2014","unstructured":"Egbe A et al (2014) Prevalence of congenital anomalies in newborns with congenital heart disease diagnosis. Ann Pediatr Cardiol 7(2):86\u201391","journal-title":"Ann Pediatr Cardiol"},{"issue":"6","key":"3308_CR12","first-page":"617","volume":"149","author":"GG Mendieta-Alcantara","year":"2013","unstructured":"Mendieta-Alcantara GG et al (2013) Incidence of congenital heart disease and factors associated with mortality in children born in two Hospitals in the State of Mexico. Gac Med Mex 149(6):617\u2013623","journal-title":"Gac Med Mex"},{"issue":"7","key":"3308_CR13","doi-asserted-by":"publisher","first-page":"a013953","DOI":"10.1101\/cshperspect.a013953","volume":"4","author":"BD Gelb","year":"2014","unstructured":"Gelb BD, Chung WK (2014) Complex genetics and the etiology of human congenital heart disease. Cold Spring Harb Perspect Med 4(7):a013953","journal-title":"Cold Spring Harb Perspect Med"},{"issue":"13","key":"3308_CR14","doi-asserted-by":"publisher","first-page":"2052","DOI":"10.1001\/jama.1969.03160260056018","volume":"209","author":"JJ Nora","year":"1969","unstructured":"Nora JJ et al (1969) Risk to offspring of parents with congenital heart defects. JAMA 209(13):2052\u20132053","journal-title":"JAMA"},{"issue":"4","key":"3308_CR15","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1161\/CIRCULATIONAHA.109.857987","volume":"120","author":"N Oyen","year":"2009","unstructured":"Oyen N et al (2009) Recurrence of congenital heart defects in families. Circulation 120(4):295\u2013301","journal-title":"Circulation"},{"issue":"10","key":"3308_CR16","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1002\/bdra.20403","volume":"79","author":"LD Botto","year":"2007","unstructured":"Botto LD et al (2007) Seeking causes: classifying and evaluating congenital heart defects in etiologic studies. Birth Defects Res A Clin Mol Teratol 79(10):714\u2013727","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"issue":"7","key":"3308_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/genes12071020","volume":"12","author":"NS Diab","year":"2021","unstructured":"Diab NS et al (2021) Molecular genetics and complex inheritance of congenital heart disease. Genes (Basel) 12(7):1","journal-title":"Genes (Basel)"},{"issue":"3","key":"3308_CR18","first-page":"263","volume":"76","author":"E Baltaxe","year":"2006","unstructured":"Baltaxe E, Zarante I (2006) Prevalence of congenital heart disease in 44,985 newborns in Colombia. Arch Cardiol Mex 76(3):263\u2013268","journal-title":"Arch Cardiol Mex"},{"issue":"5","key":"3308_CR19","doi-asserted-by":"publisher","first-page":"349","DOI":"10.4067\/S0717-75262013000500004","volume":"78","author":"C Mayorga","year":"2013","unstructured":"Mayorga C, Rodr\u00edguez RJ, Enriquez G, Alarcon J, Gamoa C, Capella D, Fischer D (2013) Cardiopat\u00edas cong\u00e9nitas: diagn\u00f3stico prenatal y seguimiento. Rev Chil Obstet Ginecol 78(5):349\u2013356","journal-title":"Rev Chil Obstet Ginecol"},{"issue":"23","key":"3308_CR20","doi-asserted-by":"publisher","first-page":"2312","DOI":"10.1016\/j.jacc.2021.09.1358","volume":"78","author":"GO Dovjak","year":"2021","unstructured":"Dovjak GO et al (2021) Abnormal extracardiac development in fetuses with congenital heart disease. J Am Coll Cardiol 78(23):2312\u20132322","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"3308_CR21","doi-asserted-by":"publisher","first-page":"433","DOI":"10.17843\/rpmesp.2019.363.4166","volume":"36","author":"CE Torres-Romucho","year":"2019","unstructured":"Torres-Romucho CE et al (2019) Factors associated with survival at one year of life in neonates with severe congenital cardiopathy in A National Hospital in Peru. Rev Peru Med Exp Salud Publica 36(3):433\u2013441","journal-title":"Rev Peru Med Exp Salud Publica"},{"issue":"5","key":"3308_CR22","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/j.acvd.2016.01.006","volume":"109","author":"M Bensemlali","year":"2016","unstructured":"Bensemlali M et al (2016) Associated genetic syndromes and extracardiac malformations strongly influence outcomes of fetuses with congenital heart diseases. Arch Cardiovasc Dis 109(5):330\u2013336","journal-title":"Arch Cardiovasc Dis"},{"issue":"3","key":"3308_CR23","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1177\/2150135115589788","volume":"6","author":"CX Florez","year":"2015","unstructured":"Florez CX et al (2015) Setting up an ECMO program in a South American country: outcomes of the first 104 pediatric patients. World J Pediatr Congenit Heart Surg 6(3):374\u2013381","journal-title":"World J Pediatr Congenit Heart Surg"},{"issue":"5","key":"3308_CR24","doi-asserted-by":"publisher","first-page":"357","DOI":"10.4070\/kcj.2015.45.5.357","volume":"45","author":"JM Ko","year":"2015","unstructured":"Ko JM (2015) Genetic syndromes associated with congenital heart disease. Korean Circ J 45(5):357\u2013361","journal-title":"Korean Circ J"},{"issue":"1","key":"3308_CR25","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1017\/S1047951113001868","volume":"25","author":"KK Bachman","year":"2015","unstructured":"Bachman KK et al (2015) Array CGH as a first-tier test for neonates with congenital heart disease. Cardiol Young 25(1):115\u2013122","journal-title":"Cardiol Young"},{"issue":"2","key":"3308_CR26","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1111\/chd.12112","volume":"9","author":"JA Connor","year":"2014","unstructured":"Connor JA et al (2014) Genetic testing practices in infants with congenital heart disease. Congenit Heart Dis 9(2):158\u2013167","journal-title":"Congenit Heart Dis"},{"issue":"5","key":"3308_CR27","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1016\/j.jpeds.2009.11.049","volume":"156","author":"J Breckpot","year":"2010","unstructured":"Breckpot J et al (2010) Array comparative genomic hybridization as a diagnostic tool for syndromic heart defects. J Pediatr 156(5):810\u2013817, 817 e1-817 e4","journal-title":"J Pediatr"},{"issue":"6","key":"3308_CR28","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1111\/j.1747-0803.2011.00582.x","volume":"6","author":"E Goldmuntz","year":"2011","unstructured":"Goldmuntz E et al (2011) Microdeletions and microduplications in patients with congenital heart disease and multiple congenital anomalies. Congenit Heart Dis 6(6):592\u2013602","journal-title":"Congenit Heart Dis"},{"issue":"22","key":"3308_CR29","doi-asserted-by":"publisher","first-page":"2778","DOI":"10.1093\/eurheartj\/ehl560","volume":"28","author":"B Thienpont","year":"2007","unstructured":"Thienpont B et al (2007) Submicroscopic chromosomal imbalances detected by array-CGH are a frequent cause of congenital heart defects in selected patients. Eur Heart J 28(22):2778\u20132784","journal-title":"Eur Heart J"},{"issue":"7","key":"3308_CR30","doi-asserted-by":"publisher","first-page":"1465","DOI":"10.1007\/s00246-017-1685-7","volume":"38","author":"GC Geddes","year":"2017","unstructured":"Geddes GC et al (2017) Genetic testing protocol reduces costs and increases rate of genetic diagnosis in infants with congenital heart disease. Pediatr Cardiol 38(7):1465\u20131470","journal-title":"Pediatr Cardiol"},{"issue":"10","key":"3308_CR31","doi-asserted-by":"publisher","first-page":"2014","DOI":"10.1016\/j.gim.2022.06.004","volume":"24","author":"BS Ferket","year":"2022","unstructured":"Ferket BS et al (2022) Cost-effectiveness frameworks for comparing genome and exome sequencing versus conventional diagnostic pathways: a scoping review and recommended methods. Genet Med 24(10):2014\u20132027","journal-title":"Genet Med"},{"issue":"1","key":"3308_CR32","doi-asserted-by":"publisher","first-page":"32","DOI":"10.25100\/cm.v45i1.1332","volume":"45","author":"W Saldarriaga-Gil","year":"2014","unstructured":"Saldarriaga-Gil W et al (2014) Evaluation of prenatal diagnosis of congenital anomalies diagnosable by prenatal ultrasound in patients in neonatal intensive care units of Cali. Colombia Colomb Med (Cali) 45(1):32\u201338","journal-title":"Colombia Colomb Med (Cali)"},{"issue":"1","key":"3308_CR33","doi-asserted-by":"publisher","first-page":"35","DOI":"10.18597\/rcog.610","volume":"55","author":"JC Posso \u00c1lvarez","year":"2004","unstructured":"Posso \u00c1lvarez JC, Sinisterra Galarza SL, Zapata GAV, de Lourido CI (2004) Estudio gen\u00e9tico en embarazadas. Rev Colomb Obstetr Ginecol 55(1):35\u201339","journal-title":"Rev Colomb Obstetr Ginecol"},{"issue":"10","key":"3308_CR34","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.1017\/S1047951121000834","volume":"31","author":"RM Muhame","year":"2021","unstructured":"Muhame RM et al (2021) Cardiac point of care ultrasound in resource limited settings to manage children with congenital and acquired heart disease. Cardiol Young 31(10):1651\u20131657","journal-title":"Cardiol Young"},{"issue":"10","key":"3308_CR35","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1080\/14767058.2019.1638905","volume":"34","author":"M Cruz-Lemini","year":"2021","unstructured":"Cruz-Lemini M et al (2021) Prenatal diagnosis of congenital heart defects: experience of the first Fetal Cardiology Unit in Mexico. J Matern Fetal Neonatal Med 34(10):1529\u20131534","journal-title":"J Matern Fetal Neonatal Med"}],"container-title":["Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-023-03308-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00246-023-03308-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-023-03308-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T14:03:38Z","timestamp":1704809018000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00246-023-03308-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,9]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["3308"],"URL":"https:\/\/doi.org\/10.1007\/s00246-023-03308-5","relation":{},"ISSN":["0172-0643","1432-1971"],"issn-type":[{"value":"0172-0643","type":"print"},{"value":"1432-1971","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,9]]},"assertion":[{"value":"11 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 September 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 October 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflict of interest or financial relationships relevant to this article to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}