{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T20:43:31Z","timestamp":1790109811606,"version":"4.0.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T00:00:00Z","timestamp":1707091200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T00:00:00Z","timestamp":1707091200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Cardiol"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We previously reported short-term outcomes for stenting of aortic coarctation (CoA) (native or re-coarctation) with newer generation low-profile stents (Valeo, Formula, and Begraft stents) in children under 30\u00a0kg. We present here the medium-term outcomes of this procedure. Retrospective review of patients weighing under 30\u00a0kg who had percutaneous stent treatments for coarctation between 2012 and 2021 was performed. Clinical and procedural data were collected; 19 patients were included. The median age at the time of procedure was 5.1 [4.1\u20136.4] years and median weight 21.0 [17.3\u201322.3] kg. One patient had a history of re-coarctation. Thirteen (68%) patients were on anti-hypertensives pre-procedure. Different types of stents were used (14 Valeo\u2122, 4 Formula<jats:sup>\u00ae<\/jats:sup> 535, 1 BeGraft), which can all be dilated to 18\u00a0mm or larger. One patient required a 9\u00a0F sheath, all others required a 7\u00a0F sheath. The narrowest diameter in the aorta increased from a median of 3.5 [3.0\u20134.5] to 9.4 [8.9\u20139.8] mm, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001; there was a reduction in the median pressure gradient across the coarctation from 35.0 [30.0\u201343.0] to 5.0 [0\u201310.0] mmHg, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001. There were no intra-procedural complications. Follow-up was for a median of 56.0 [13.0\u201365.0] months. Five (26%) of patients underwent re-intervention after a median time frame of 40.0 [39.5\u201352.0] months; four had balloon dilation, one had repeat stent implantation. Five (26%) patients were on anti-hypertensive agent(s) post-intervention. Our single centre experience demonstrates that percutaneous stenting for coarctation of aorta in children under 30\u00a0kg, with low-profile stents, had no significant complications during the median follow-up time of 56\u00a0months. This study demonstrated that the procedure is safe and effective for short and medium-term therapy in this group of patients with a 26% re-intervention rate. A quarter of patients remained on\u00a0anti-hypertensive medication post stenting, emphasizing the importance of long-term follow-up.<\/jats:p>","DOI":"10.1007\/s00246-023-03402-8","type":"journal-article","created":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T14:02:41Z","timestamp":1707141761000},"page":"544-551","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Medium-Term Outcomes of Stent Therapy for Aortic Coarctation in Children Under 30\u00a0kg with New Generation Low-Profile Stents: A Follow-Up Study of a Single Centre Experience"],"prefix":"10.1007","volume":"45","author":[{"given":"Jack J. 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The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}