{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T12:49:02Z","timestamp":1765889342375,"version":"3.44.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Cardiol"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1007\/s00246-024-03577-8","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T01:01:40Z","timestamp":1720659700000},"page":"1616-1620","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Atrial Arrhythmia and Bradycardia as a Presentation of Congenital Long QT Syndrome"],"prefix":"10.1007","volume":"46","author":[{"given":"Vithida","family":"Sueblinvong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Varga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,7,11]]},"reference":[{"issue":"11","key":"3577_CR1","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1111\/j.1540-8167.1998.tb00096.x","volume":"9","author":"AP Gorgels","year":"1998","unstructured":"Gorgels AP, Eadley FA, Zaman L, Kantoch MJ, Halees ZA (1998) The long QT syndrome with impaired atrioventricular conduction: a malignant variant in infants. J Cardiovasc Electrophysiol 9(11):1225\u20131232","journal-title":"J Cardiovasc Electrophysiol"},{"issue":"3","key":"3577_CR2","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1067\/mob.2001.117973","volume":"185","author":"E Beinder","year":"2001","unstructured":"Beinder E, Grancay T, Men\u00e9ndez T, Singer H, Hofbeck M (2001) Fetal sinus bradycardia and the long QT syndrome. Am J Obstet Gynecol 185(3):743\u2013747","journal-title":"Am J Obstet Gynecol"},{"issue":"43","key":"3577_CR3","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1016\/j.jacc.2003.09.049","volume":"1","author":"JM Lupoglazoff","year":"2004","unstructured":"Lupoglazoff JM, Denjoy I, Villazon E, Fressart V, Bertin F, Bozio A et al (2004) Long QT syndrome in neonates-conduction disorders associated with HERG mutations and sinus bradycardia with KCNQ1 mutations. J Am Coll Cardiol 1(43):826\u2013830","journal-title":"J Am Coll Cardiol"},{"issue":"10","key":"3577_CR4","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1139\/y11-070","volume":"89","author":"K Calloe","year":"2011","unstructured":"Calloe K, Schmitt N, Grubb S, Pfeiffer R, David JP, Kanter R et al (2011) Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5A. Can J Physiol Pharmacol 89(10):723\u2013736","journal-title":"Can J Physiol Pharmacol"},{"issue":"10","key":"3577_CR5","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1046\/j.1540-8167.2003.03165.x","volume":"14","author":"P Kirchhof","year":"2003","unstructured":"Kirchhof P, Eckardt L, Franz MR, M\u00f6nnig G, Loh P, Wedekind H et al (2003) Prolonged atrial action potential durations and polymorphic atrial tachyarrhythmias in patients with long QT syndrome. J Cardiovasc Electrophysiol 14(10):1027\u20131033","journal-title":"J Cardiovasc Electrophysiol"},{"issue":"10","key":"3577_CR6","doi-asserted-by":"publisher","first-page":"e007213","DOI":"10.1161\/CIRCEP.119.007213","volume":"12","author":"PG Platonov","year":"2019","unstructured":"Platonov PG, McNitt S, Polonsky B, Rosero SZ, Zareba W (2019) Atrial fibrillation in long QT syndrome by genotype. Circ Arrhythm Electrophysiol 12(10):e007213","journal-title":"Circ Arrhythm Electrophysiol"},{"issue":"9","key":"3577_CR7","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1016\/j.hrthm.2013.07.012","volume":"10","author":"K Guerrier","year":"2013","unstructured":"Guerrier K, Czosek RJ, Spar DS, Anderson J (2013) Long QT genetics manifesting as atrial fibrillation. Heart Rhythm 10(9):1351\u20131353","journal-title":"Heart Rhythm"},{"issue":"5","key":"3577_CR8","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1016\/j.hrthm.2008.02.007","volume":"5","author":"JN Johnson","year":"2008","unstructured":"Johnson JN, Tester DJ, Perry J, Salisbury BA, Reed CR, Ackerman MJ (2008) Prevalence of early-onset atrial fibrillation in congenital long QT syndrome. Heart Rhythm 5(5):704\u2013709","journal-title":"Heart Rhythm"},{"issue":"4","key":"3577_CR9","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1161\/CIRCGENETICS.111.962597","volume":"5","author":"MS Olesen","year":"2012","unstructured":"Olesen MS, Yuan L, Liang B, Holst AG, Nielsen N, Nielsen JB et al (2012) High prevalence of long QT syndrome-associated SCN5A variants in patients with early-onset lone atrial fibrillation. Circ Cardiovasc Genet 5(4):450\u2013459","journal-title":"Circ Cardiovasc Genet"},{"issue":"5","key":"3577_CR10","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.jacc.2015.10.093","volume":"67","author":"R Almomani","year":"2016","unstructured":"Almomani R, Verhagen JMA, Herkert JC, Brosens E, van Spaendonck-Zwarts KY, Asimaki A et al (2016) Biallelic truncating mutations in ALPK3 cause severe pediatric cardiomyopathy. J Am Coll Cardiol 67(5):515\u2013525","journal-title":"J Am Coll Cardiol"},{"issue":"33","key":"3577_CR11","doi-asserted-by":"publisher","first-page":"2586","DOI":"10.1093\/eurheartj\/ehw160","volume":"37","author":"DG Phelan","year":"2016","unstructured":"Phelan DG, Anderson DJ, Howden SE, Wong RCB, Hickey PF, Pope K et al (2016) ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy. Eur Heart J 37(33):2586\u20132590","journal-title":"Eur Heart J"},{"issue":"32","key":"3577_CR12","doi-asserted-by":"publisher","first-page":"3063","DOI":"10.1093\/eurheartj\/ehab424","volume":"42","author":"LR Lopes","year":"2021","unstructured":"Lopes LR, Garcia-Hern\u00e1ndez S, Lorenzini M, Futema M, Chumakova O, Zateyshchikov D et al (2021) Alpha-protein kinase 3 (ALPK3) truncating variants are a cause of autosomal dominant hypertrophic cardiomyopathy. Eur Heart J 42(32):3063\u20133073","journal-title":"Eur Heart J"},{"issue":"6","key":"3577_CR13","doi-asserted-by":"publisher","first-page":"e003127","DOI":"10.1161\/CIRCGEN.120.003127","volume":"13","author":"C Cheawsamoot","year":"2020","unstructured":"Cheawsamoot C, Phokaew C, Chetruengchai W, Chantranuwat P, Puwanant S, Tongsima S et al (2020) A pathogenic variant in ALPK3 Is associated with an autosomal dominant adult-onset hypertrophic cardiomyopathy. Circ Genomic Precis Med 13(6):e003127","journal-title":"Circ Genomic Precis Med"},{"key":"3577_CR14","unstructured":"Atrial fibrillation, familial, 3 (Concept Id: C1837014)-MedGen-NCBI. https:\/\/www.ncbi.nlm.nih.gov\/medgen\/373232 Accessed 11 May 2024"},{"key":"3577_CR15","unstructured":"Short QT syndrome type 2 (Concept Id: C1865019)-MedGen-NCBI. https:\/\/www.ncbi.nlm.nih.gov\/medgen\/355890 Accessed 11 May 2024"},{"key":"3577_CR16","unstructured":"Jervell and Lange-Nielsen syndrome (Concept Id: C0022387)-MedGen-NCBI. https:\/\/www.ncbi.nlm.nih.gov\/medgen\/5929 Accessed 11 May 2024"},{"issue":"1","key":"3577_CR17","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1097\/HCO.0000000000000587","volume":"34","author":"SP Etheridge","year":"2019","unstructured":"Etheridge SP, Asaki SY, Niu MCI (2019) A personalized approach to long QT syndrome. Curr Opin Cardiol 34(1):46","journal-title":"Curr Opin Cardiol"},{"issue":"12","key":"3577_CR18","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1161\/CIRCULATIONAHA.116.021823","volume":"134","author":"AAM Wilde","year":"2016","unstructured":"Wilde AAM, Moss AJ, Kaufman ES, Shimizu W, Peterson DR, Benhorin J et al (2016) Clinical aspects of type 3 long-QT syndrome. Circulation 134(12):872\u2013882","journal-title":"Circulation"},{"issue":"3","key":"3577_CR19","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1016\/S0002-8703(97)70074-7","volume":"134","author":"M Stramba-Badiale","year":"1997","unstructured":"Stramba-Badiale M, Goulene K, Schwartz PJ (1997) Effects of \u03b2-adrenergic blockade on dispersion of ventricular repolarization in newborn infants with prolonged QT interval. Am Heart J 134(3):406\u2013410","journal-title":"Am Heart J"},{"issue":"4","key":"3577_CR20","first-page":"181","volume":"7","author":"S Sarkar","year":"2007","unstructured":"Sarkar S, Brumund M, Darling R, Snyder CS (2007) Survival of a newborn with 2:1 atrioventricular block, long QT syndrome, and torsades de pointes. Ochsner J 7(4):181\u2013184","journal-title":"Ochsner J"},{"issue":"146","key":"3577_CR21","doi-asserted-by":"publisher","first-page":"104274","DOI":"10.1016\/j.phrs.2019.104274","volume":"1","author":"E Grandi","year":"2019","unstructured":"Grandi E, Ripplinger CM (2019) Antiarrhythmic mechanisms of beta blocker therapy. Pharmacol Res 1(146):104274","journal-title":"Pharmacol Res"}],"container-title":["Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-024-03577-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00246-024-03577-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-024-03577-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T20:17:11Z","timestamp":1757103431000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00246-024-03577-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,11]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["3577"],"URL":"https:\/\/doi.org\/10.1007\/s00246-024-03577-8","relation":{},"ISSN":["0172-0643","1432-1971"],"issn-type":[{"type":"print","value":"0172-0643"},{"type":"electronic","value":"1432-1971"}],"subject":[],"published":{"date-parts":[[2024,7,11]]},"assertion":[{"value":"9 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 July 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors did not receive support from any organization for the submitted work.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}