{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T08:45:21Z","timestamp":1776847521324,"version":"3.51.2"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T00:00:00Z","timestamp":1752537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T00:00:00Z","timestamp":1752537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Cardiol"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study investigates the benefits of coiling aortopulmonary collaterals (APCs) before Fontan completion and prior to heart transplantation due to failed Fontan. The advantages of APC coiling in these situations remain unclear. Outcomes were compared between those undergoing the Fontan operation between June 2013 and December 2015, who did not undergo coiling of APCs, and those between January 2016 and May 2022, when aggressive coiling of APCs was performed. The 1-year post-transplant survival was compared for patients from Memphis, TN, where aggressive APC coiling was performed before transplantation, to a previously published report from St. Louis, MO, where APCs were actively coiled and an earlier era when they were not. The 44 Fontan patients with prior APC coiling were compared to 22 patients matched for age, diagnosis, and hemodynamics. The chest tube output (22.6\u2009\u00b1\u20096.1 vs. 41.8\u2009\u00b1\u20098.2\u00a0mL\/kg;\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.001), the chest tube duration (5.1\u2009\u00b1\u20091.1 vs. 10.3\u2009\u00b1\u20094.5\u00a0days;\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.001), and the hospital length of stay (9.9\u2009\u00b1\u20091.7 vs. 27.4\u2009\u00b1\u20096.2\u00a0days;\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.001) were significantly lower for those who had APC coiling compared to those who did not. In St. Louis, MO, when APCs were not coiled before transplantation (\n                    <jats:italic>N<\/jats:italic>\n                    \u2009=\u200927), the 1-year survival rate was 66%, which improved to 85% (\n                    <jats:italic>N<\/jats:italic>\n                    \u2009=\u200920) in the era of APC coiling. In the Memphis experience (\n                    <jats:italic>N<\/jats:italic>\n                    \u2009=\u200925) with aggressive APC coiling, the 1-year survival rate was 92% (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.018). APC coiling before Fontan completion decreases chest tube output and hospitalization days. It may also improve the 1-year survival rate after heart transplantation for children with failed Fontan.\n                  <\/jats:p>","DOI":"10.1007\/s00246-025-03946-x","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T06:47:13Z","timestamp":1752562033000},"page":"1639-1648","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Benefits of Coiling Aorto-Pulmonary Collaterals in Children with Complex Congenital Heart Diseases"],"prefix":"10.1007","volume":"47","author":[{"given":"Ashley","family":"Molloy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil","family":"Tailor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Hunter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umar","family":"Boston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiva","family":"Sathanandam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyam","family":"Sathanandam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,15]]},"reference":[{"key":"3946_CR1","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/0003-4975(94)00120-V","volume":"59","author":"H Ichikawa","year":"1995","unstructured":"Ichikawa H, Yagihara T, Kishimoto H, Isobe F, Yamamoto F, Nishigaki K, Matsuki O, Fujita T (1995) Extent of aortopulmonary collateral blood flow as a risk factor for Fontan operations. Ann Thorac Surg 59:433\u2013437","journal-title":"Ann Thorac Surg"},{"key":"3946_CR2","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1016\/S0003-4975(99)00782-1","volume":"68","author":"KR Kanter","year":"1999","unstructured":"Kanter KR, Vincent RN, Raviele AA (1999) Importance of acquired systemic-to-pulmonary collaterals in the Fontan operation. Ann Thorac Surg 68:969\u2013974 (discussion 974)","journal-title":"Ann Thorac Surg"},{"key":"3946_CR3","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1053\/pcsu.2002.31501","volume":"5","author":"KR Kanter","year":"2002","unstructured":"Kanter KR, Vincent RN (2002) Management of aortopulmonary collateral arteries in Fontan patients: occlusion improves clinical outcome. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 5:48\u201354","journal-title":"Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu"},{"key":"3946_CR4","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1016\/S0002-8703(96)90092-7","volume":"131","author":"RL Spicer","year":"1996","unstructured":"Spicer RL, Uzark KC, Moore JW, Mainwaring RD, Lamberti JJ (1996) Aortopulmonary collateral vessels and prolonged pleural effusions after modified Fontan procedures. Am Heart J 131:1164\u20131168","journal-title":"Am Heart J"},{"key":"3946_CR5","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1161\/CIRCIMAGING.111.966986","volume":"5","author":"AC Glatz","year":"2012","unstructured":"Glatz AC, Rome JJ, Small AJ, Gillespie MJ, Dori Y, Harris MA, Keller MS, Fogel MA, Whitehead KK (2012) Systemic-to-pulmonary collateral flow, as measured by cardiac magnetic resonance imaging, is associated with acute post-Fontan clinical outcomes. Circ Cardiovasc Imaging 5:218\u2013225","journal-title":"Circ Cardiovasc Imaging"},{"key":"3946_CR6","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/S0003-4975(01)02813-2","volume":"72","author":"SM Bradley","year":"2001","unstructured":"Bradley SM, McCall MM, Sistino JJ, Radtke WA (2001) Aortopulmonary collateral flow in the Fontan patient: does it matter? Ann Thorac Surg 72:408\u2013415","journal-title":"Ann Thorac Surg"},{"key":"3946_CR7","doi-asserted-by":"publisher","first-page":"1664","DOI":"10.1016\/j.jtcvs.2003.09.011","volume":"127","author":"A Gupta","year":"2004","unstructured":"Gupta A, Daggett C, Behera S, Ferraro M, Wells W, Starnes V (2004) Risk factors for persistent pleural effusions after the extracardiac Fontan procedure. J Thorac Cardiovasc Surg 127:1664\u20131669","journal-title":"J Thorac Cardiovasc Surg"},{"key":"3946_CR8","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.1016\/S0003-4975(99)01088-7","volume":"69","author":"DB McElhinney","year":"2000","unstructured":"McElhinney DB, Reddy VM, Tworetzky W, Petrossian E, Hanley FL, Moore P (2000) Incidence and implications of systemic to pulmonary collaterals after bidirectional cavopulmonary anastomosis. Ann Thorac Surg 69:1222\u20131228","journal-title":"Ann Thorac Surg"},{"key":"3946_CR9","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.jacc.2004.02.058","volume":"44","author":"PS Ro","year":"2004","unstructured":"Ro PS, Rychik J, Cohen MS, Mahle WT, Rome JJ (2004) Diagnostic assessment before Fontan operation in patients with bidirectional cavopulmonary anastomosis: are noninvasive methods sufficient? J Am Coll Cardiol 44:184\u2013187","journal-title":"J Am Coll Cardiol"},{"key":"3946_CR10","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.ahj.2011.03.021","volume":"162","author":"P Banka","year":"2011","unstructured":"Banka P, Sleeper LA, Atz AM, Cowley CG, Gallagher D, Gillespie MJ, Graham EM, Margossian R, McCrindle BW, Sang CJ, Williams IA, Newburger JW (2011) Practice variability and outcomes of coil embolization of aortopulmonary collaterals before Fontan completion: a report from the Pediatric Heart Network Fontan Cross-Sectional Study. Am Heart J 162:125\u2013130","journal-title":"Am Heart J"},{"key":"3946_CR11","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1161\/CIRCIMAGING.108.834192","volume":"2","author":"L Grosse-Wortmann","year":"2009","unstructured":"Grosse-Wortmann L, Al-Otay A, Yoo SJ (2009) Aortopulmonary collaterals after bidirectional cavopulmonary connection or Fontan completion: quantification with MRI. Circ Cardiovasc Imaging 2:219\u2013225","journal-title":"Circ Cardiovasc Imaging"},{"key":"3946_CR12","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1161\/CIRCIMAGING.108.832113","volume":"2","author":"KK Whitehead","year":"2009","unstructured":"Whitehead KK, Gillespie MJ, Harris MA et al (2009) Noninvasive quantification of systemic-to-pulmonary collateral flow: a major source of inefficiency in patients with superior cavopulmonary connections. Circ Cardiovasc Imaging 2:405\u2013411","journal-title":"Circ Cardiovasc Imaging"},{"key":"3946_CR13","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/0735-1097(93)90836-P","volume":"22","author":"JK Triedman","year":"1993","unstructured":"Triedman JK, Bridges ND, Mayer JE Jr et al (1993) Prevalence and risk factors for aortopulmonary collateral vessels after Fontan and bidirectional Glenn procedures. J Am Coll Cardiol 22:207\u2013215","journal-title":"J Am Coll Cardiol"},{"key":"3946_CR14","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1161\/CIRCINTERVENTIONS.112.972265","volume":"6","author":"Y Dori","year":"2013","unstructured":"Dori Y, Glatz AC, Hanna BD et al (2013) Acute effects of embolizing systemic-to-pulmonary arterial collaterals on blood flow in patients with superior cavopulmonary connections: a pilot study. Circ Cardiovasc Intervent 6:101\u2013106","journal-title":"Circ Cardiovasc Intervent"},{"key":"3946_CR15","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1161\/CIRCULATIONAHA.107.738559","volume":"117","author":"P Khairy","year":"2008","unstructured":"Khairy P, Fernandes SM, Mayer JE Jr et al (2008) Long-term survival, modes of death, and predictors of mortality in patients with Fontan surgery. Circulation 117:85\u201392","journal-title":"Circulation"},{"key":"3946_CR16","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/j.athoracsur.2012.02.052","volume":"94","author":"RK Voeller","year":"2012","unstructured":"Voeller RK, Epstein DJ, Guthrie TJ et al (2012) Trends in the indications and survival in pediatric heart transplants: a 24-year single-center experience in 307 patients. Ann Thorac Surg 94:807\u2013815","journal-title":"Ann Thorac Surg"},{"key":"3946_CR17","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/j.healun.2011.12.013","volume":"31","author":"MD Everitt","year":"2012","unstructured":"Everitt MD, Boyle GJ, Schechtman KB et al (2012) Early survival after heart transplant in young infants is lowest after failed single-ventricle palliation: a multi-institutional study. J Heart Lung Transplant 31:509\u2013516","journal-title":"J Heart Lung Transplant"},{"key":"3946_CR18","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1161\/CIRCULATIONAHA.105.548016","volume":"114","author":"D Bernstein","year":"2006","unstructured":"Bernstein D, Naftel D, Chin C et al (2006) Outcome of listing for cardiac transplantation for failed Fontan: a multi-institutional study. Circulation 114:273\u2013280","journal-title":"Circulation"},{"key":"3946_CR19","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1016\/j.athoracsur.2012.05.075","volume":"94","author":"T Karamlou","year":"2012","unstructured":"Karamlou T, Diggs BS, Welke K et al (2012) Impact of single-ventricle physiology on death after heart transplantation in adults with congenital heart disease. Ann Thorac Surg 94:1281\u20131287","journal-title":"Ann Thorac Surg"},{"key":"3946_CR20","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.healun.2011.11.004","volume":"31","author":"JR Kovach","year":"2012","unstructured":"Kovach JR, Naftel DC, Pearce FB et al (2012) Comparison of risk factors and outcomes for pediatric patients listed for heart transplantation after bidirectional Glenn and after Fontan: an analysis from the Pediatric Heart Transplant Study. J Heart Lung Transplant 31:133\u2013139","journal-title":"J Heart Lung Transplant"},{"key":"3946_CR21","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1016\/j.jtcvs.2011.12.039","volume":"143","author":"RR Davies","year":"2012","unstructured":"Davies RR, Sorabella RA, Yang J et al (2012) Outcomes after transplantation for \u201cfailed\u201d Fontan: a single-institution experience. J Thorac Cardiovasc Surg 143:1183\u20131192","journal-title":"J Thorac Cardiovasc Surg"},{"key":"3946_CR22","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1016\/j.healun.2012.02.003","volume":"31","author":"KE Simpson","year":"2012","unstructured":"Simpson KE, Cibulka N, Lee CK et al (2012) Failed Fontan heart transplant candidates with preserved vs impaired ventricular ejection: 2 distinct patient populations. J Heart Lung Transplant 31:545\u2013547","journal-title":"J Heart Lung Transplant"},{"key":"3946_CR23","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1161\/CIRCULATIONAHA.114.009120","volume":"131","author":"KR Schumacher","year":"2015","unstructured":"Schumacher KR, Almond C, Singh TP et al (2015) Predicting graft loss by 1 year in pediatric heart transplantation candidates: an analysis of the Pediatric Heart Transplant Study database. Circulation 131:890\u2013898","journal-title":"Circulation"},{"key":"3946_CR24","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1016\/S1053-2498(03)00305-X","volume":"23","author":"US Krishnan","year":"2004","unstructured":"Krishnan US, Lamour JM, Hsu DT et al (2004) Management of aortopulmonary collaterals in children following cardiac transplantation for complex congenital heart disease. J Heart Lung Transplant 23:564\u2013569","journal-title":"J Heart Lung Transplant"},{"issue":"7","key":"3946_CR25","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1016\/j.healun.2016.02.005","volume":"35","author":"JR Miller","year":"2016","unstructured":"Miller JR, Simpson KE, Epstein DJ, Lancaster TS, Henn MC, Schuessler RB, Balzer DT, Shahanavaz S, Murphy JJ, Canter CE, Eghtesady P, Boston US (2016) Improved survival after heart transplant for failed Fontan patients with preserved ventricular function. J Heart Lung Transplant 35(7):877\u2013883","journal-title":"J Heart Lung Transplant"}],"container-title":["Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-025-03946-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00246-025-03946-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-025-03946-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T17:02:41Z","timestamp":1772125361000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00246-025-03946-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,15]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["3946"],"URL":"https:\/\/doi.org\/10.1007\/s00246-025-03946-x","relation":{},"ISSN":["0172-0643","1432-1971"],"issn-type":[{"value":"0172-0643","type":"print"},{"value":"1432-1971","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,15]]},"assertion":[{"value":"26 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Dr. Shyam Sathanandam is a consultant and proctor for Abbott. The other authors have no financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}