{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T17:59:18Z","timestamp":1772128758816,"version":"3.50.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Cardiol"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s00246-025-03970-x","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T18:29:13Z","timestamp":1753468153000},"page":"1788-1797","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pulmonary Artery Pulsatility Index: A Novel Marker for Risk Assessment and Prognosis in Pediatric Idiopathic Pulmonary Arterial Hypertension"],"prefix":"10.1007","volume":"47","author":[{"given":"Emine G\u00fcl\u015fah","family":"Torun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nevin","family":"\u00d6zdemiro\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denizhan","family":"Ba\u011frul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130brahim","family":"Ece","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,25]]},"reference":[{"issue":"38","key":"3970_CR1","doi-asserted-by":"publisher","first-page":"3618","DOI":"10.1093\/eurheartj\/ehac237","volume":"43","author":"M Humbert","year":"2022","unstructured":"Humbert M, Kovacs G, Hoeper MM et al (2022) 2022 ESC\/ ERS guidelines for the diagnosis and treatment of pulmonary hypertension developed by the task force for the diagnosis and treatment of (ESC) and the European Respiratory Society (ERS). Eur Heart J 43(38):3618\u20133731","journal-title":"Eur Heart J"},{"issue":"5","key":"3970_CR2","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1016\/j.pcl.2020.06.005","volume":"67","author":"BS Frank","year":"2020","unstructured":"Frank BS, Ivy DD (2020) Pediatric pulmonary arterial hypertension. Pediatr Clin North Am 67(5):903\u2013921","journal-title":"Pediatr Clin North Am"},{"issue":"4","key":"3970_CR3","doi-asserted-by":"publisher","first-page":"2401324","DOI":"10.1183\/13993003.01324-2024","volume":"64","author":"G Kovacs","year":"2024","unstructured":"Kovacs G, Bartolome S, Denton CP et al (2024) Definition, classification and diagnosis of pulmonary hypertension. Eur Respir J 64(4):2401324","journal-title":"Eur Respir J"},{"issue":"9815","key":"3970_CR4","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/S0140-6736(11)61621-8","volume":"379","author":"RMF Berger","year":"2012","unstructured":"Berger RMF, Beghetti M et al (2012) Clinical features of paediatric pulmonary hypertension: a registry study. Lancet 379(9815):537\u2013546","journal-title":"Lancet"},{"issue":"17","key":"3970_CR5","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1136\/hrt.2009.182378","volume":"96","author":"S Moledina","year":"2010","unstructured":"Moledina S, Hislop AA, Foster H et al (2010) Childhood idiopathic pulmonary arterial hypertension: a national cohort study. Heart 96(17):1401\u20131406","journal-title":"Heart"},{"issue":"1","key":"3970_CR6","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1161\/CIRCULATIONAHA.111.026591","volume":"125","author":"RJ Barst","year":"2012","unstructured":"Barst RJ, McGoon MD, Elliott CG et al (2012) Survival in childhood pulmonary arterial hypertension: insights from the registry to evaluate early and long-term pulmonary arterial hypertension disease management. Circulation 125(1):113\u2013122","journal-title":"Circulation"},{"issue":"2","key":"3970_CR7","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1161\/CIRCULATIONAHA.109.898122","volume":"122","author":"RL Benza","year":"2010","unstructured":"Benza RL, Miller DP, Gomberg-Maitland M et al (2010) Predicting survival in pulmonary arterial hypertension: insights from the registry to evaluate early and long-term pulmonary arterial hypertension disease management (REVEAL). Circulation 122(2):164\u2013172","journal-title":"Circulation"},{"key":"3970_CR8","doi-asserted-by":"publisher","first-page":"3835","DOI":"10.1002\/ehf2.13450","volume":"8","author":"Y Lim","year":"2021","unstructured":"Lim Y, Low T, Chan SP et al (2021) Does pulmonary artery pulsatility index predict mortality in pulmonary arterial hypertension? ESC Heart Fail 8:3835\u201344","journal-title":"ESC Heart Fail"},{"issue":"1","key":"3970_CR9","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.healun.2015.06.009","volume":"35","author":"G Kang","year":"2016","unstructured":"Kang G, Ha R, Banerjee D (2016) Pulmonary artery pulsatility index predicts right ventricular failure after left ventricular assist device implantation. J Hear Lung Transplant 35(1):67\u201373","journal-title":"J Hear Lung Transplant"},{"issue":"5","key":"3970_CR10","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1053\/j.jvca.2019.09.023","volume":"34","author":"LQ Rong","year":"2020","unstructured":"Rong LQ, Rahouma M, Neuburger PJ et al (2020) Use of pulmonary artery pulsatility index in cardiac surgery. J Cardiothorac Vasc Anesth 34(5):1220\u20131225","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"3970_CR11","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01323-2024","author":"F Dardi","year":"2024","unstructured":"Dardi F, Boucly A, Benza R et al (2024) Risk stratification and treatment goals in pulmonary arterial hypertension. Eur Respir J. https:\/\/doi.org\/10.1183\/13993003.01323-2024","journal-title":"Eur Respir J"},{"key":"3970_CR12","doi-asserted-by":"publisher","first-page":"1035453","DOI":"10.3389\/fcvm.2022.1035453","volume":"9","author":"C Lokhorst","year":"2022","unstructured":"Lokhorst C, van der Werf S, Berger RMF, Douwes JM (2022) Risk stratification in adult and pediatric pulmonary arterial hypertension: a systematic review. Front Cardiovasc Med 9:1035453","journal-title":"Front Cardiovasc Med"},{"key":"3970_CR13","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01345-2024","author":"D Ivy","year":"2024","unstructured":"Ivy D, Rosenzweig EB, Abman SH et al (2024) Embracing the challenges of neonatal and paediatric pulmonary hypertension. Eur Respir J. https:\/\/doi.org\/10.1183\/13993003.01345-2024","journal-title":"Eur Respir J"},{"issue":"2","key":"3970_CR14","doi-asserted-by":"publisher","first-page":"1700740","DOI":"10.1183\/13993003.00740-2017","volume":"50","author":"MM Hoeper","year":"2017","unstructured":"Hoeper MM, Kramer T, Pan Z et al (2017) Mortality in pulmonary arterial hypertension: prediction by the 2015 European pulmonary hypertension guidelines risk stratification model. Eur Respir J 50(2):1700740","journal-title":"Eur Respir J"},{"issue":"6","key":"3970_CR15","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1016\/j.chest.2022.11.038","volume":"163","author":"Y Qian","year":"2023","unstructured":"Qian Y, Quan R, Chen X et al (2023) Characteristics, long-term survival, and risk assessment of pediatric pulmonary arterial hypertension in China insights from a national multicenter prospective registry. Chest 163(6):1531\u20131542","journal-title":"Chest"},{"issue":"5","key":"3970_CR16","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1016\/j.hlc.2018.04.280","volume":"28","author":"S Mazimba","year":"2020","unstructured":"Mazimba S, Welch TS, Mwansa H et al (2020) Haemodynamically derived pulmonary artery pulsatility index predicts mortality in pulmonary arterial hypertension. Heart Lung Circ 28(5):752\u201360","journal-title":"Heart Lung Circ"},{"issue":"2","key":"3970_CR17","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.cardfail.2015.10.019","volume":"22","author":"KJ Morine","year":"2016","unstructured":"Morine KJ, Kiernan MS, Pham DT et al (2016) Pulmonary artery pulsatility index is associated with right ventricular failure after left ventricular assist device surgery. J Card Fail 22(2):110\u2013116","journal-title":"J Card Fail"},{"issue":"4","key":"3970_CR18","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.cardfail.2020.01.014","volume":"26","author":"S Cesini","year":"2020","unstructured":"Cesini S, Bhagra S, Pettit SJ (2020) Low pulmonary artery pulsatility index is associated with adverse outcomes in ambulatory patients with advanced heart failure. J Card Fail 26(4):352\u2013359","journal-title":"J Card Fail"},{"issue":"4","key":"3970_CR19","first-page":"593","volume":"80","author":"R Korabathina","year":"2012","unstructured":"Korabathina R, Heffernan KS, Paruchuri V et al (2012) The pulmonary artery pulsatility index identifies severe right ventricular dysfunction in acute inferior myocardial infarction. Catheter Cardiovasc Interv 80(4):593\u2013600","journal-title":"Catheter Cardiovasc Interv"},{"issue":"1","key":"3970_CR20","doi-asserted-by":"publisher","first-page":"1801900","DOI":"10.1183\/13993003.01900-2018","volume":"53","author":"A Vonk Noordegraaf","year":"2019","unstructured":"Vonk Noordegraaf A, Chin KM, Haddad F et al (2019) Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: an update. Eur Respir J 53(1):1801900","journal-title":"Eur Respir J"},{"key":"3970_CR21","doi-asserted-by":"publisher","DOI":"10.3390\/children11101152","author":"FE Smits","year":"2024","unstructured":"Smits FE, Lokhorst C, Haarman MG et al (2024) The pulmonary artery pulsatility index provides no additional prognostic information in pediatric pulmonary arterial hypertension. Children. https:\/\/doi.org\/10.3390\/children11101152","journal-title":"Children"},{"issue":"3","key":"3970_CR22","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1097\/MAT.0000000000000808","volume":"65","author":"DS Raymer","year":"2019","unstructured":"Raymer DS, Moreno JD, Sintek MA et al (2019) The combination of tricuspid annular plane systolic excursion and HeartMate risk score predicts right ventricular failure after left ventricular assist device implantation. ASAIO J 65(3):247\u2013251","journal-title":"ASAIO J"},{"issue":"13","key":"3970_CR23","doi-asserted-by":"publisher","first-page":"2995","DOI":"10.3390\/jcm10132995","volume":"10","author":"R Kazimierczyk","year":"2021","unstructured":"Kazimierczyk R, Kazimierczyk E, Knapp M et al (2021) Echocardiographic assessment of right ventricular\u2013arterial coupling in predicting prognosis of pulmonary arterial hypertension patients. J Clin Med. 10(13):2995","journal-title":"J Clin Med."},{"issue":"4","key":"3970_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2023.103290","volume":"22","author":"A Colalillo","year":"2023","unstructured":"Colalillo A, Hoffmann-Vold AM, Pellicano C et al (2023) The role of TAPSE\/sPAP ratio in predicting pulmonary hypertension and mortality in the systemic sclerosis EUSTAR cohort. Autoimmun Rev 22(4):103290","journal-title":"Autoimmun Rev"}],"container-title":["Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-025-03970-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00246-025-03970-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-025-03970-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T17:02:47Z","timestamp":1772125367000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00246-025-03970-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,25]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["3970"],"URL":"https:\/\/doi.org\/10.1007\/s00246-025-03970-x","relation":{},"ISSN":["0172-0643","1432-1971"],"issn-type":[{"value":"0172-0643","type":"print"},{"value":"1432-1971","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,25]]},"assertion":[{"value":"23 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The study was conducted in accordance with the principles of the Declaration of Helsinki and received approval from the Turkish Ministry of Health and the hospital\u2019s human research ethics committee (decision number: 1-24-493, date: August 28, 2024).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}