{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T21:00:00Z","timestamp":1771966800102,"version":"3.50.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Cardiol"],"DOI":"10.1007\/s00246-026-04202-6","type":"journal-article","created":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T07:44:31Z","timestamp":1771919071000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Significant Congenital Cardiovascular Malformations and Falling Birth Rates: The Nevada Experience"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5446-268X","authenticated-orcid":false,"given":"William N.","family":"Evans","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3472-9217","authenticated-orcid":false,"given":"Ruben J.","family":"Acherman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1198-5787","authenticated-orcid":false,"given":"Humberto","family":"Restrepo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,24]]},"reference":[{"issue":"11","key":"4202_CR1","doi-asserted-by":"publisher","first-page":"1693","DOI":"10.1016\/j.mayocp.2024.09.004","volume":"99","author":"D Dilmaghani","year":"2024","unstructured":"Dilmaghani D, Ainsworth AJ, Nath KA, Garovic VD (2024) Decreasing fertility rate in the united states: demographics, challenges, and consequences. Mayo Clin Proc 99(11):1693\u20131697. https:\/\/doi.org\/10.1016\/j.mayocp.2024.09.004","journal-title":"Mayo Clin Proc"},{"issue":"6","key":"4202_CR2","doi-asserted-by":"publisher","first-page":"100476","DOI":"10.1016\/j.ajogmf.2021.100476","volume":"3","author":"RA McLaren Jr","year":"2021","unstructured":"McLaren RA Jr, Trejo FE, Blitz MJ et al (2021) )COVID-related lockdowns and birth rates in New York. Am J Obstet Gynecol MFM 3(6):100476 https:\/\/doi.org\/10.1016\/j.ajogmf.2021.100476","journal-title":"Am J Obstet Gynecol MFM"},{"issue":"4","key":"4202_CR3","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1136\/heart.83.4.414","volume":"83","author":"C Wren","year":"2000","unstructured":"Wren C, Richmond S, Donaldson L (2000) Temporal variability in birth prevalence of cardiovascular malformations. Heart 83(4):414\u2013419. https:\/\/doi.org\/10.1136\/heart.83.4.414","journal-title":"Heart"},{"issue":"3","key":"4202_CR4","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1017\/S1047951110001940","volume":"21","author":"WN Evans","year":"2011","unstructured":"Evans WN, Acherman RJ, Castillo WJ, Restrepo H (2011) The changing occurrences of tetralogy of Fallot and simple transposition of the great arteries in Southern Nevada. Cardiol Young 21(3):281\u2013285 Epub 2011 Jan 28. PMID: 21272425","journal-title":"Cardiol Young"},{"key":"4202_CR5","doi-asserted-by":"publisher","first-page":"109550","DOI":"10.1016\/j.envres.2020.109550","volume":"186","author":"J Patel","year":"2020","unstructured":"Patel J, Nembhard WN, Politis MD et al (2020) Maternal occupational exposure to polycyclic aromatic hydrocarbons and the risk of isolated congenital heart defects among offspring. Environ Res 186:109550. https:\/\/doi.org\/10.1016\/j.envres.2020.109550Epub 2020 Apr 18. PMID: 32335433; PMCID: PMC8756335","journal-title":"Environ Res"},{"issue":"19","key":"4202_CR6","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1161\/CIR.0000000000001139","volume":"147","author":"LS Mehta","year":"2023","unstructured":"Mehta LS, Velarde GP, Lewey J et al (2023) The impact of race and ethnicity: a scientific statement from the American Heart Association. Circulation 147(19):1471\u20131487. https:\/\/doi.org\/10.1161\/CIR.0000000000001139","journal-title":"Circulation"},{"key":"4202_CR7","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.1016\/j.ppedcard.2021.101433","volume":"64","author":"WN Evans","year":"2022","unstructured":"Evans WN, Acherman RJ, Restrepo H (2022) Critical congenital heart disease and maternal comorbidities: An observation. Prog Ped Cardiol 64:1058\u20139813","journal-title":"Prog Ped Cardiol"},{"issue":"7","key":"4202_CR8","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1007\/s00246-014-0921-7","volume":"35","author":"A Egbe","year":"2014","unstructured":"Egbe A, Uppu S, Lee S, Ho D, Srivastava S (2014) Changing prevalence of severe congenital heart disease: a population-based study. Pediatr Cardiol 35(7):1232\u20131238. https:\/\/doi.org\/10.1007\/s00246-014-0921-7","journal-title":"Pediatr Cardiol"},{"issue":"12","key":"4202_CR9","doi-asserted-by":"publisher","first-page":"4472","DOI":"10.1111\/jocs.15979","volume":"36","author":"WN Evans","year":"2021","unstructured":"Evans WN, Acherman RJ, Ciccolo ML, Lehoux J, Restrepo H (2021) Prenatal diagnosis in Nevada for patients undergoing cardiovascular surgery in the first six months. J Card Surg 36(12):4472\u20134475. https:\/\/doi.org\/10.1111\/jocs.15979","journal-title":"J Card Surg"},{"issue":"4 pt 1","key":"4202_CR10","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1111\/j.1475-6773.2006.00551.x","volume":"41","author":"K Fiscella","year":"2006","unstructured":"Fiscella K, Freemont AM (2006) Use of geocoding and surname analysis to estimate race and ethnicity. Health Serv Res 41(4 pt 1):1482\u20131500","journal-title":"Health Serv Res"},{"issue":"4 pt 1","key":"4202_CR11","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1111\/j.1475-6773.2006.00550.x","volume":"41","author":"II Wei","year":"2006","unstructured":"Wei II, Virning BA, John DA, Morgan RO (2006) Using a Spanish surname match to improve identification of Hispanic women in Medicare administrative data. Health Serv Res 41(4 pt 1):1469\u20131481","journal-title":"Health Serv Res"},{"key":"4202_CR12","unstructured":"Centers for Disease Control and Prevention (2026). National Center for Health Statistics https:\/\/www.cdc.gov\/nchs\/fastats\/state-and-territorial-data.htm. Accessed Jan 3"},{"issue":"12","key":"4202_CR13","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.7863\/jum.2007.26.12.1715","volume":"26","author":"RJ Acherman","year":"2007","unstructured":"Acherman RJ, Evans WN, Luna CF et al (2007) Prenatal detection of congenital heart disease in southern Nevada: the need for universal fetal cardiac evaluation. J Ultrasound Med 26(12):1715\u20131719","journal-title":"J Ultrasound Med"},{"issue":"2","key":"4202_CR14","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1007\/s00246-014-0996-1","volume":"36","author":"W Evans","year":"2015","unstructured":"Evans W, Castillo W, Rollins R et al (2015) Moving towards universal prenatal detection of critical congenital heart disease in southern Nevada: a community-wide program. Pediatr Cardiol 36(2):281\u2013288","journal-title":"Pediatr Cardiol"},{"issue":"6","key":"4202_CR15","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1177\/2150135119873847","volume":"10","author":"WN Evans","year":"2019","unstructured":"Evans WN, Acherman RJ, Ciccolo ML et al (2019) Detecting critical congenital heart disease in Nevada. World J Pediatr Congenit Heart Surg 10(6):702\u2013706","journal-title":"World J Pediatr Congenit Heart Surg"},{"issue":"7","key":"4202_CR16","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1016\/j.echo.2023.04.014","volume":"36","author":"AJ Moon-Grady","year":"2023","unstructured":"Moon-Grady AJ, Donofrio MT, Gelehrter S et al (2023) Guidelines and recommendations for performance of the fetal echocardiogram: an update from the American Society of Echocardiography. J Am Soc Echocardiogr 36(7):679\u2013723. https:\/\/doi.org\/10.1016\/j.echo.2023.04.014","journal-title":"J Am Soc Echocardiogr"},{"key":"4202_CR17","doi-asserted-by":"publisher","first-page":"101385","DOI":"10.1016\/j.ppedcard.2021.101385","volume":"62","author":"WN Evans","year":"2021","unstructured":"Evans WN, Acherman RJ, Restrepo H (2021) Advanced maternal age and critical congenital cardiac malformations in Nevada. Prog Pediatr Cardiol 62:101385. https:\/\/doi.org\/10.1016\/j.ppedcard.2021.101385","journal-title":"Prog Pediatr Cardiol"},{"issue":"9","key":"4202_CR18","doi-asserted-by":"publisher","first-page":"2137","DOI":"10.1002\/ajmg.a.34130","volume":"2155A","author":"A Miller","year":"2011","unstructured":"Miller A, Riehle-Colarusso T, Siffel C, Fr\u00edas JL, Correa A (2011) Maternal age and prevalence of isolated congenital heart defects in an urban area of the United States. Am J Med Genet A 2155A(9):2137\u20132145. https:\/\/doi.org\/10.1002\/ajmg.a.34130","journal-title":"Am J Med Genet A"},{"key":"4202_CR19","first-page":"1","volume":"477","author":"JA Martin","year":"2023","unstructured":"Martin JA, Hamilton BE, Osterman MJK (2023) Births in the United States, 2022. NCHS Data Brief 477:1\u20138","journal-title":"NCHS Data Brief"},{"key":"4202_CR20","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1097\/AOG.0000000000005258","volume":"142","author":"BO Berger","year":"2023","unstructured":"Berger BO, Jeffers NK, Wolfson C, Gemmill A (2023) Role of maternal age in increasing severe maternal morbidity rates in the United States. Obstet Gynecol 142:371\u2013380","journal-title":"Obstet Gynecol"},{"issue":"232","key":"4202_CR21","first-page":"1","volume":"1","author":"TJ Mathews","year":"2016","unstructured":"Mathews TJ, Hamilton BE (2016) Mean age of mothers is on the rise: United States, 2000-2014. NCHS Data Brief 1(232):1\u20138","journal-title":"NCHS Data Brief"},{"issue":"2","key":"4202_CR22","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1038\/s41372-023-01834-x","volume":"44","author":"RA Gamber","year":"2024","unstructured":"Gamber RA, Blonsky H, McDowell M, Lakshminrusimha S (2024) Declining birth rates, increasing maternal age and neonatal intensive care unit admissions. J Perinatol 44(2):203\u2013208. https:\/\/doi.org\/10.1038\/s41372-023-01834-x","journal-title":"J Perinatol"},{"key":"4202_CR23","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1007\/978-3-031-07563-6_10","volume-title":"Pediatric Cardiology: Fetal, Pediatric, and Adult Congenital Heart Diseases","author":"PM Zegelbone","year":"2024","unstructured":"Zegelbone PM, Patel SS (2024) Teratogenic factors contributing to the development of congenital heart defects. In: Abdulla R, Anderson RH, Carl L, Backer CL et al (eds) Pediatric Cardiology: Fetal, Pediatric, and Adult Congenital Heart Diseases. Springer, Cham, Switzerland, pp 149\u2013160"},{"key":"4202_CR24","doi-asserted-by":"publisher","DOI":"10.1002\/jum.70155","author":"WN Evans","year":"2025","unstructured":"Evans WN, Acherman RJ, Kip KT et al (2025) Embedding fetal cardiologists in maternal-fetal-medicine clinics and near universal state-wide detection of critical cardiovascular malformations: the Nevada experience. J Ultrasound Med. https:\/\/doi.org\/10.1002\/jum.70155","journal-title":"J Ultrasound Med"},{"issue":"5","key":"4202_CR25","doi-asserted-by":"publisher","first-page":"357","DOI":"10.4070\/kcj.2015.45.5.357","volume":"45","author":"JM Ko","year":"2015","unstructured":"Ko JM (2015) Genetic syndromes associated with congenital heart disease. Korean Circ J 45(5):357\u2013361. https:\/\/doi.org\/10.4070\/kcj.2015.45.5.357","journal-title":"Korean Circ J"},{"key":"4202_CR26","doi-asserted-by":"publisher","first-page":"205","DOI":"10.2147\/RMHP.S447493","volume":"17","author":"X Lu","year":"2024","unstructured":"Lu X, Li G, Wu Q et al (2024) Prenatal diagnosis of congenital heart disease and voluntary termination of pregnancy: A population-based study in Qingdao, China. Risk Manage Healthc Policy 17:205\u2013212","journal-title":"Risk Manage Healthc Policy"},{"issue":"25","key":"4202_CR27","doi-asserted-by":"publisher","first-page":"8761","DOI":"10.1080\/14767058.2021.2004115","volume":"35","author":"WN Evans","year":"2022","unstructured":"Evans WN, Acherman RJ, Restrepo H (2022) Prenatal diagnosis of significant congenital heart disease and elective termination of pregnancy in Nevada. J Matern Fetal Neonatal Med 35(25):8761\u20138766. https:\/\/doi.org\/10.1080\/14767058.2021.2004115","journal-title":"J Matern Fetal Neonatal Med"},{"key":"4202_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1542\/pedsos.2024-000411","volume":"1","author":"SY Tseng","year":"2025","unstructured":"Tseng SY, Alvarado C, Conroy S et al (2025) The Dobbs decision and incidence of live births with cyanotic congenital heart disease. Pediatr Open Sci 1:1\u20138. https:\/\/doi.org\/10.1542\/pedsos.2024-000411","journal-title":"Pediatr Open Sci"},{"issue":"261","key":"4202_CR29","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1186\/s12910-025-01327-w","volume":"12","author":"F Kalhor","year":"2025","unstructured":"Kalhor F, Tagharrobi Z, Ghaderian M et al (2025) Ethical dilemmas in continuing pregnancy after a prenatal diagnosis of congenital heart defects: a systematic review and narrative synthesis. BMC Med Ethics 12(261):174. https:\/\/doi.org\/10.1186\/s12910-025-01327-w","journal-title":"BMC Med Ethics"},{"issue":"9","key":"4202_CR30","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1001\/jamacardio.2018.1944","volume":"3","author":"AA Kon","year":"2018","unstructured":"Kon AA (2018) Ethical implications of prenatal screening for congenital heart disease. JAMA Cardiol 3(9):837\u2013838. https:\/\/doi.org\/10.1001\/jamacardio.2018.1944","journal-title":"JAMA Cardiol"},{"issue":"2","key":"4202_CR31","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1002\/pd.6739","volume":"45","author":"WN Evans","year":"2025","unstructured":"Evans WN, Acherman RJ, Kip KT et al (2025) Approaching universal prenatal detection of significant cardiovascular malformations in Nevada. Prenat Diagn 45(2):196\u2013203. https:\/\/doi.org\/10.1002\/pd.6739Epub 2024 Dec 31. PMID: 39739413","journal-title":"Prenat Diagn"},{"issue":"6","key":"4202_CR32","doi-asserted-by":"publisher","first-page":"B2","DOI":"10.1016\/j.ajog.2020.02.040","volume":"222","author":"CA Combs","year":"2020","unstructured":"Combs CA, Hameed AB, Friedman AM, Hoskins IA (2020) Special statement: proposed quality metrics to assess accuracy of prenatal detection of congenital heart defects. Am J Obstet Gynecol 222(6):B2\u2013B9","journal-title":"Am J Obstet Gynecol"}],"container-title":["Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-026-04202-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00246-026-04202-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-026-04202-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T20:03:14Z","timestamp":1771963394000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00246-026-04202-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,24]]},"references-count":32,"alternative-id":["4202"],"URL":"https:\/\/doi.org\/10.1007\/s00246-026-04202-6","relation":{},"ISSN":["0172-0643","1432-1971"],"issn-type":[{"value":"0172-0643","type":"print"},{"value":"1432-1971","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,24]]},"assertion":[{"value":"21 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors have no competing interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"The authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national guidelines on human experimentation (Belmont Report) and with the Helsinki Declaration of 1975, as revised in 2008, and has been approved by the Institutional Committees of Sunrise Hospital and Medical Center (IRB # 25-1124).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}