{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T12:39:53Z","timestamp":1785155993824,"version":"3.55.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:00:00Z","timestamp":1776384000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:00:00Z","timestamp":1776384000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Cardiol"],"DOI":"10.1007\/s00246-026-04260-w","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T08:33:30Z","timestamp":1776414810000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Transjugular Liver Biopsy in Children Undergoing Fontan Surgery: Safety and Comparison of Fibrosis Grade with Non-invasive Tests"],"prefix":"10.1007","author":[{"given":"Rebeca","family":"Del \u00c1lamo Pe\u00f1a","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda del Mar","family":"Tol\u00edn Hernani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Miranda Cid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Ballesteros Tejerizo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Gil Villanueva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Rinc\u00f3n Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Asenjo Tornel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Isabel","family":"Torres Cuenca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9sar","family":"S\u00e1nchez S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,17]]},"reference":[{"key":"4260_CR1","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1055\/a-2556-4897","volume":"45","author":"MB Hilscher","year":"2025","unstructured":"Hilscher MB, Johnson JN (2025) Fontan-associated liver disease. Semin Liver Dis 45:114\u2013128","journal-title":"Semin Liver Dis"},{"key":"4260_CR2","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.jjcc.2019.02.016","volume":"74","author":"TT Gordon-Walker","year":"2019","unstructured":"Gordon-Walker TT, Bove K, Veldtman G (2019) Fontan-associated liver disease: a review. J Cardiol 74:223\u2013232","journal-title":"J Cardiol"},{"key":"4260_CR3","doi-asserted-by":"publisher","first-page":"3764","DOI":"10.1016\/j.ijcard.2013.06.008","volume":"168","author":"RW Elder","year":"2013","unstructured":"Elder RW, McCabe NM, Hebson C et al (2013) Features of portal hypertension are associated with major adverse events in Fontan patients: the VAST study. Int J Cardiol 168:3764\u20139","journal-title":"Int J Cardiol"},{"key":"4260_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jacadv.2025.101694","volume":"4","author":"JY Cao","year":"2025","unstructured":"Cao JY, Wales KM, d\u2019Udekem Y, Celermajer DS, Cordina R, Majumdar A (2025) Prevalence, risk factors, and prognosis for Fontan-associated liver disease: a systematic review and exploratory meta-analysis. JACC ADV 4:1\u201313","journal-title":"JACC ADV"},{"key":"4260_CR5","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-025-03781-0","author":"A Gozzi","year":"2025","unstructured":"Gozzi A, Vedovelli L, Bergonzoni E, Cao I, Angeli E, Zanoni R et al (2025) Fontan\u2011associated liver disease (FALD) in the EUROFontan experience. An insight into European awareness. Pediatr Cardiol. https:\/\/doi.org\/10.1007\/s00246-025-03781-0","journal-title":"Pediatr Cardiol"},{"issue":"12","key":"4260_CR6","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.14120","volume":"34","author":"SS Vaikunth","year":"2020","unstructured":"Vaikunth SS, Higgins JP, Concepcion W et al (2020) Does liver biopsy accurately measure fibrosis in Fontan-associated liver disease? A comparison of liver biopsy precombined heart and liver transplant and liver explant posttransplant. Clin Transplant 34(12):e14120","journal-title":"Clin Transplant"},{"issue":"05","key":"4260_CR7","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1016\/j.jhep.2023.07.013","volume":"79","author":"L T\u00e9llez","year":"2023","unstructured":"T\u00e9llez L, Payanc\u00e9 A, Tjwa E et al (2023) EASL-ERN position paper on liver involvement in patients with Fontan-type circulation. J Hepatol 79(05):1270\u20131301","journal-title":"J Hepatol"},{"issue":"6","key":"4260_CR8","doi-asserted-by":"publisher","first-page":"e234","DOI":"10.1161\/CIR.0000000000000696","volume":"140","author":"J Rychik","year":"2019","unstructured":"Rychik J, Atz AM, Celermajer DS, Deal BJ, Gatzoulis MA, Gewillig MH et al (2019) Evaluation and management of the child and adult with Fontan circulation: a scientific statement from the American Heart Association. Circulation 140(6):e234\u2013e284","journal-title":"Circulation"},{"key":"4260_CR9","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1007\/s00270-024-03761-6","volume":"47","author":"MU Shahid","year":"2024","unstructured":"Shahid MU, Frenkel Y, Kuc N, Golowa Y, Cynamon J (2024) Transfemoral-Transcaval liver biopsy (TFTC) and Transjugular Liver Biopsy (TJLB) in patients with Fontan-associated liver disease (FALD). Cardiovasc Intervent Radiol 47:875\u2013882. https:\/\/doi.org\/10.1007\/s00270-024-03761-6","journal-title":"Cardiovasc Intervent Radiol"},{"key":"4260_CR10","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezaf100","author":"S Horie","year":"2025","unstructured":"Horie S, Shikata F, Oka N, Okamura T, Matsunaga Y, Matsui K et al (2025) Liver fibrosis marker is a potential predictor of the development of Fontan associated liver diseases. Eur J Cardiothorac Surg. https:\/\/doi.org\/10.1093\/ejcts\/ezaf100","journal-title":"Eur J Cardiothorac Surg"},{"issue":"8","key":"4260_CR11","doi-asserted-by":"publisher","first-page":"2097","DOI":"10.1253\/circj.cj-12-1281","volume":"77","author":"M Shiraishi","year":"2013","unstructured":"Shiraishi M, Fuse S, Mori T, Doyama A, Honjyo T et al (2013) N-terminal pro-brain natriuretic peptide as a useful diagnostic marker of acute Kawasaki disease in children. Circ J 77(8):2097\u2013101. https:\/\/doi.org\/10.1253\/circj.cj-12-1281","journal-title":"Circ J"},{"issue":"10","key":"4260_CR12","first-page":"707","volume":"103","author":"M Gewillig","year":"2017","unstructured":"Gewillig M (2017) The Fontan circulation. Heart 103(10):707\u201313","journal-title":"Heart"},{"key":"4260_CR13","doi-asserted-by":"publisher","first-page":"e012529","DOI":"10.1161\/JAHA.119.0125299","volume":"9","author":"SL Rathgeber","year":"2020","unstructured":"Rathgeber SL, Guttman OR, Lee AF, Voss C, Hemphill NM et al (2020) Liver disease: spectrum of disease in children and adolescents. J Am Heart Assoc 9:e012529. https:\/\/doi.org\/10.1161\/JAHA.119.0125299","journal-title":"J Am Heart Assoc"},{"key":"4260_CR14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2024.114389","volume":"277","author":"AJ Gumm","year":"2025","unstructured":"Gumm AJ, Rand EB (2025) Fontan-associated liver disease. J Pediatr 277:114389. https:\/\/doi.org\/10.1016\/j.jpeds.2024.114389","journal-title":"J Pediatr"},{"key":"4260_CR15","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.ijcard.2020.11.037","volume":"328","author":"AA Borquez","year":"2021","unstructured":"Borquez AA, Silva-Sepulveda J, Lee JW, Vavinskaya V, Vodkin I, El-Sabrout H et al (2021) Transjugular liver biopsy for Fontan associated liver disease surveillance: technique, outcomes and hemodynamic correlation. Int J Cardiol 328:83\u201388","journal-title":"Int J Cardiol"},{"issue":"3","key":"4260_CR16","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1007\/s00247-018-4311-9","volume":"49","author":"A Srinivasan","year":"2019","unstructured":"Srinivasan A, Guzman AK, Rand EB, Rychik J, Goldberg DJ, Russo PA et al (2019) Percutaneous liver biopsy in Fontan patients. Pediatr Radiol 49(3):342\u2013350. https:\/\/doi.org\/10.1007\/s00247-018-4311-9","journal-title":"Pediatr Radiol"},{"key":"4260_CR17","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1002\/hep.21178","volume":"43","author":"RK Sterling","year":"2006","unstructured":"Sterling RK, Lissen E, Clumeck N, APRICOT Clinical Investigators et al (2006) Development of a simple noninvasive index to predict significant fibrosis in patients with HIV\/HCV coinfection. Hepatology 43:1317\u20131325","journal-title":"Hepatology"},{"key":"4260_CR18","doi-asserted-by":"publisher","DOI":"10.3390\/children12091131","volume":"12","author":"F Yamazaki","year":"2025","unstructured":"Yamazaki F, Kamimura H, Endo S, Miida S, Maruyama H et al (2025) Revisiting hepatic fibrosis risk in congenital heart disease: insights from non-invasive markers and echocardiography. Children 12:1131. https:\/\/doi.org\/10.3390\/children12091131","journal-title":"Children"},{"issue":"4","key":"4260_CR19","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1016\/j.ejrad.2016.02.002","volume":"85","author":"JM Bae","year":"2016","unstructured":"Bae JM, Jeon TY, Kim JS, Kim S, Hwang SM, Yoo SY et al (2016) Fontan associated liver disease: spectrum of US findings. Eur J Radiol 85(4):850\u2013856. https:\/\/doi.org\/10.1016\/j.ejrad.2016.02.002","journal-title":"Eur J Radiol"},{"issue":"1","key":"4260_CR20","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1007\/s00431-021-04163-3","volume":"181","author":"R De Bruyne","year":"2022","unstructured":"De Bruyne R, Vandekerckhove K, Van Overschelde H, Hendricx F, Vande Walle C, De Groote K et al (2022) Noninvasive assessment of liver abnormalities in pediatric Fontan patients. Eur J Pediatr 181(1):159\u2013169. https:\/\/doi.org\/10.1007\/s00431-021-04163-3","journal-title":"Eur J Pediatr"},{"key":"4260_CR21","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-025-06366-4","author":"J Razavi","year":"2025","unstructured":"Razavi J, Trout AT, Morin CE, Opotowsky AR, Smith CR et al (2025) Liver stiffness measured by MR elastography in children and adults with Fontan circulation: defining expected values and clinical associations. Pediatr Radiol. https:\/\/doi.org\/10.1007\/s00247-025-06366-4","journal-title":"Pediatr Radiol"},{"key":"4260_CR22","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/71251939","volume":"2016","author":"B Chen","year":"2016","unstructured":"Chen B, Schreiber RA, Human DG, Potts JE, Guttman OR (2016) Assessment of liver stiffness in pediatric Fontan patients using transient elastography. Can J Gastroenterol Hepatol 2016:7125193. https:\/\/doi.org\/10.1155\/2016\/71251939","journal-title":"Can J Gastroenterol Hepatol"},{"issue":"6","key":"4260_CR23","doi-asserted-by":"publisher","first-page":"e85336","DOI":"10.7759\/cureus.85336","volume":"17","author":"H Sakae","year":"2025","unstructured":"Sakae H, Tanoue S, Mawatari S et al (2025) Fontan-associated liver disease: predictors of elevated liver stiffness and the role of transient elastography in long-term follow-up. Cureus 17(6):e85336. https:\/\/doi.org\/10.7759\/cureus.85336","journal-title":"Cureus"},{"key":"4260_CR24","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1002\/jgh3.12967","volume":"7","author":"M Gill","year":"2023","unstructured":"Gill M, Mudaliar S, Prince D, Ni Than N, Cordina R, Majumdar A (2023) Poor correlation of 2D shear wave elastography andtransient elastography in Fontan-associated liver disease: a head-to-head comparison. JGH Open: An Open Access J Gastroenterol Hepatol 7:690\u2013697","journal-title":"JGH Open: An Open Access J Gastroenterol Hepatol"},{"key":"4260_CR25","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1097\/PAS.0000000000002418","volume":"49","author":"RC Reed","year":"2025","unstructured":"Reed RC, Yeh M, Files MD, Price J, Ahmed H et al (2025) Validation of congestive hepatic fibrosis score in pediatric and adult Fontan-associated liver disease. Am J Surg Pathol 49:942\u2013947","journal-title":"Am J Surg Pathol"},{"key":"4260_CR26","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.ijcard.2016.02.041","volume":"209","author":"G Agnoletti","year":"2016","unstructured":"Agnoletti G, Ferraro G, Bordese R, Marini D, Gala S, Bergamasco L et al (2016) Fontan circulation causes early, severe liver damage. Should we offer patients a tailored strategy? Int J Cardiol 209:60\u201365. https:\/\/doi.org\/10.1016\/j.ijcard.2016.02.041","journal-title":"Int J Cardiol"}],"container-title":["Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-026-04260-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00246-026-04260-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-026-04260-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T08:33:31Z","timestamp":1776414811000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00246-026-04260-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,17]]},"references-count":26,"alternative-id":["4260"],"URL":"https:\/\/doi.org\/10.1007\/s00246-026-04260-w","relation":{},"ISSN":["0172-0643","1432-1971"],"issn-type":[{"value":"0172-0643","type":"print"},{"value":"1432-1971","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,17]]},"assertion":[{"value":"6 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}