{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T21:39:34Z","timestamp":1792705174557,"version":"4.5.0"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Cardiol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Atrial Leadless pacemaker implantspresent a new treatment for sinus node dysfunction in complex cardiac anatomies. The Aveir-VR single chamber pacemaker can be placed in the atrium to control atrial flutter, or in the ventricle to control bradycardia. In this case report, we present four cases of the implantation of the Aveir VR in the atrium of male pediatric patients to treat sinus node dysfunction. Retrospective review of patients with symptomatic sinus node dysfunction and atrially placed Aveir-VRs was performed at UC Davis between April 2024 and April 2026. Femoral access was the route of implantation for all 5 patients. Trans-esophageal echocardiography was used in all cases. The patients\u2019 ages ranged between 14\u201317-years and follow-up appointments were held between 1\u201323-months. Immediately post-procedure, impedances were 380\u20131460 Ohms, thresholds at 0.4\u00a0ms were 2.25\u20133.5\u00a0V, and P-waves were between 1.7\u20133\u00a0mV. Follow-up impedance was between 390\u2013720 Ohms for the patients, thresholds were 0.5\u20131.25\u00a0V at 0.2\u20130.4\u00a0ms, P-waves were between 4.5\u20139.1\u00a0mV, and pacing percentages were between 12\u201369%. This case series demonstrates the successful implant of Aveir VR leadless pacemaker in five young patients for sinus node dysfunction.<\/jats:p>","DOI":"10.1007\/s00246-026-04507-6","type":"journal-article","created":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T08:21:44Z","timestamp":1792657304000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Aveir VR for Atrial Leadless Pacing in Young Patients"],"prefix":"10.1007","author":[{"given":"Anirud","family":"Aiyer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Cortez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,22]]},"reference":[{"key":"4507_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ipej.2024.04.009","author":"JA Aguayo","year":"2024","unstructured":"Aguayo JA, Cortez D (2024) Atrial placement of Aveir-VR leadless pacemaker in a patient with complex cardiac anatomy. Indian Pacing Electrophysiol J. https:\/\/doi.org\/10.1016\/j.ipej.2024.04.009","journal-title":"Indian Pacing Electrophysiol J"},{"issue":"9","key":"4507_CR2","doi-asserted-by":"publisher","first-page":"679","DOI":"10.2217\/fca-2021-0139","volume":"18","author":"A El-Bokl","year":"2022","unstructured":"El-Bokl A, Siddeek H, Hou C, Leslie A, Jimenez E, Cortez D (2022) Pediatric Micra leadless pacemaker implantation via internal jugular and femoral veins: experience with 11 patients. Future Cardiol 18(9):679\u2013686. https:\/\/doi.org\/10.2217\/fca-2021-0139","journal-title":"Future Cardiol"},{"issue":"8","key":"4507_CR3","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1111\/pace.14764","volume":"46","author":"A Wong","year":"2023","unstructured":"Wong A, Petersen MJ, Davidson S, Cortez D (2023) First report of an Aveir retrievable leadless pacemaker in a pediatric patient, via internal jugular vein access. Pacing Clin Electrophysiol 46(8):824\u2013826. https:\/\/doi.org\/10.1111\/pace.14764","journal-title":"Pacing Clin Electrophysiol"},{"issue":"2","key":"4507_CR4","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.ipej.2024.01.008","volume":"24","author":"ZS Rahmat","year":"2024","unstructured":"Rahmat ZS, Cortez D (2024) Retrievable leadless pacemakers (Aveir VR) may be beneficial in adult patients with congenital heart disease. Indian Pacing Electrophysiol J 24(2):57\u201362. https:\/\/doi.org\/10.1016\/j.ipej.2024.01.008","journal-title":"Indian Pacing Electrophysiol J"},{"issue":"11","key":"4507_CR5","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1016\/j.hrcr.2023.08.011","volume":"9","author":"YE Kaptein","year":"2023","unstructured":"Kaptein YE, Mortada ME (2023) Implant-to-implant diagnostics and programming of dual-chamber leadless pacemaker in an orthotopic heart transplant recipient. HeartRhythm Case Rep 9(11):811\u2013814. https:\/\/doi.org\/10.1016\/j.hrcr.2023.08.011","journal-title":"HeartRhythm Case Rep"},{"key":"4507_CR6","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1056\/NEJMoa1500528","volume":"372","author":"AM Gillinov","year":"2015","unstructured":"Gillinov AM, Gelijns AC, Parides MK, DeRose JJ Jr, Moskowitz AJ, Voisine P, Ailawadi G, Bouchard D, Smith PK, Mack MJ, Acker MA, Mullen JC, Rose EA, Chang HL, Puskas JD, Couderc JP, Gardner TJ, Varghese R, Horvath KA, Bolling SF, Michler RE, Geller NL, Ascheim DD, Miller MA, Baqiella E, Moquete EG, Williams P, Taddei-Peters WC, O\u2019Gara PT, Blackstone EH, Argenziano M, Investigators CTSN (2015) Surgical ablation of atrial fibrillation during mitral-valve surgery. N Engl J Med 372:1399\u20131409","journal-title":"N Engl J Med"},{"issue":"6","key":"4507_CR7","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.2217\/fca-2020-0169","volume":"17","author":"H Siddeek","year":"2021","unstructured":"Siddeek H, Jimenez E, Ambrose M, Braunlin E, Steinberger J, Bass J, Cortez D (2021) Pediatric Micra leadless pacemaker implantation via the internal jugular and femoral vein: a single-center, US experience. Future Cardiol 17(6):1116\u20131122. https:\/\/doi.org\/10.2217\/fca-2020-0169","journal-title":"Future Cardiol"},{"issue":"25","key":"4507_CR8","doi-asserted-by":"publisher","first-page":"2360","DOI":"10.1056\/NEJMoa2300080","volume":"388","author":"RE Knops","year":"2023","unstructured":"Knops RE, Reddy VY, Ip JE, Doshi R, Exner DV, Defaye P, Canby R, Bongiorni MG, Shoda M, Hindricks G, Neu\u017eil P, Rashtian M, Breeman KTN, Nevo JR, Ganz L, Hubbard C, Cantillon DJ (2023) A dual-chamber leadless pacemaker. N Engl J Med 388(25):2360\u20132370. https:\/\/doi.org\/10.1056\/NEJMoa2300080","journal-title":"N Engl J Med"},{"issue":"4","key":"4507_CR9","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1016\/j.hrcr.2023.01.012","volume":"9","author":"P Neu\u017eil","year":"2023","unstructured":"Neu\u017eil P, Petr\u016f J, Chovanec M, H\u00e1la P, \u0160ediv\u00e1 L, Reddy VY (2023) Retrieval and replacement of a helix-fixation leadless pacemaker at 9 years post-implant. HeartRhythm Case Rep 9(4):258\u2013262. https:\/\/doi.org\/10.1016\/j.hrcr.2023.01.012","journal-title":"HeartRhythm Case Rep"}],"container-title":["Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-026-04507-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00246-026-04507-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00246-026-04507-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T21:02:01Z","timestamp":1792702921000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00246-026-04507-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,22]]},"references-count":9,"alternative-id":["4507"],"URL":"https:\/\/doi.org\/10.1007\/s00246-026-04507-6","relation":{},"ISSN":["0172-0643","1432-1971"],"issn-type":[{"value":"0172-0643","type":"print"},{"value":"1432-1971","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,22]]},"assertion":[{"value":"27 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}