{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:17:21Z","timestamp":1763036241813},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2007,6,14]],"date-time":"2007-06-14T00:00:00Z","timestamp":1181779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2007,6,14]],"date-time":"2007-06-14T00:00:00Z","timestamp":1181779200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Radiol"],"published-print":{"date-parts":[[2007,8]]},"DOI":"10.1007\/s00247-007-0486-1","type":"journal-article","created":{"date-parts":[[2007,6,14]],"date-time":"2007-06-14T06:16:08Z","timestamp":1181801768000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Bone malformations in Proteus syndrome: an analysis of bone structural changes and their evolution during growth"],"prefix":"10.1007","volume":"37","author":[{"given":"Ugo E.","family":"Pazzaglia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giampiero","family":"Beluffi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Bonaspetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Ranchetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,6,14]]},"reference":[{"key":"486_CR1","first-page":"291","volume":"15","author":"MM Cohen Jr","year":"1979","unstructured":"Cohen MM Jr, Hayden PW (1979) A newly recognized hamartomatous syndrome. Birth Defects Orig Artic Ser 15:291\u2013296","journal-title":"Birth Defects Orig Artic Ser"},{"key":"486_CR2","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1007\/BF00661895","volume":"140","author":"HR Wiedemann","year":"1983","unstructured":"Wiedemann HR, Burgio GR, Aldenhoff P et al (1983) The Proteus syndrome. Partial gigantism of the hands and\/or feet, nevi, hemihypertrophy, subcutaneous tumors, macrocephaly or other skull anomalies and possible accelerated growth and visceral affections. Eur J Pediatr 140:5\u201312","journal-title":"Eur J Pediatr"},{"key":"486_CR3","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1148\/rg.244035726","volume":"24","author":"CA Jamis-Dow","year":"2004","unstructured":"Jamis-Dow CA, Turner J, Biesecker LG et al (2004) Radiologic manifestation of Proteus syndrome. Radiographics 24:1051\u20131068","journal-title":"Radiographics"},{"key":"486_CR4","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1007\/BF02072076","volume":"149","author":"G Beluffi","year":"1990","unstructured":"Beluffi G, Di Giulio G, Fiori P (1990) Pelvic lipomatosis in the Proteus syndrome: a further diagnostic sign. Eur J Pediatr 149:866","journal-title":"Eur J Pediatr"},{"key":"486_CR5","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1002\/(SICI)1096-8628(19981002)79:4<311::AID-AJMG14>3.0.CO;2-U","volume":"79","author":"LG Biesecker","year":"1998","unstructured":"Biesecker LG, Peters KF, Darling TN et al (1998) Clinical differentiation between Proteus syndrome and hemihyperplasia: description of a distinct form of hemihyperplasia. Am J Med Genet 79:311\u2013318","journal-title":"Am J Med Genet"},{"key":"486_CR6","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1002\/(SICI)1096-8628(19990611)84:5<389::AID-AJMG1>3.0.CO;2-O","volume":"84","author":"LG Biesecker","year":"1999","unstructured":"Biesecker LG, Happle R, Mulliken JB et al (1999) Proteus syndrome: diagnostic criteria, differential diagnosis, and patient evaluation. Am J Med Genet 84:389\u2013395","journal-title":"Am J Med Genet"},{"key":"486_CR7","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1002\/ajmg.a.30327","volume":"130","author":"JT Turner","year":"2004","unstructured":"Turner JT, Cohen MM Jr, Biesecker LG (2004) Reassessment of the Proteus syndrome literature: application of diagnostic criteria to published cases. Am J Med Genet A 130:111\u2013122","journal-title":"Am J Med Genet A"},{"key":"486_CR8","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1002\/ajmg.1320460209","volume":"46","author":"C Shaw","year":"1993","unstructured":"Shaw C, Bourke J, Dixon J (1993) Proteus syndrome with cardiomyopathy and a myocardial mass. Am J Med Genet 46:145\u2013148","journal-title":"Am J Med Genet"},{"key":"486_CR9","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1542\/peds.76.6.984","volume":"76","author":"T Costa","year":"1985","unstructured":"Costa T, Fitch N, Azouz EM (1985) Proteus syndrome: report of two cases with pelvic lipomatosis. Pediatrics 76:984\u2013989","journal-title":"Pediatrics"},{"key":"486_CR10","first-page":"599","volume":"50","author":"S Ben Becher","year":"1993","unstructured":"Ben Becher S, Bouaziz A, Harbi MM et al (1993) Syndrome de Prot\u00e9e associ\u00e9 \u00e0 une lithiase r\u00e9nale avec reflux v\u00e9sico-ur\u00e9t\u00e9ral. Arch Fr Pediatr 50:599\u2013601","journal-title":"Arch Fr Pediatr"},{"key":"486_CR11","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1002\/ajmg.1320470516","volume":"47","author":"F Skovby","year":"1993","unstructured":"Skovby F, Graham JM Jr, Sonne-Holm S et al (1993) Compromise of the spinal canal in Proteus syndrome. Am J Med Genet 47:656\u2013659","journal-title":"Am J Med Genet"},{"key":"486_CR12","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1111\/j.1346-8138.1992.tb03265.x","volume":"19","author":"Y Hagari","year":"1992","unstructured":"Hagari Y, Aso M, Shimao S et al (1992) Proteus syndrome: report of the first Japanese case with special reference to differentiation from Klippel Trenaunay Weber syndrome. J Dermatol 19: 477\u2013480","journal-title":"J Dermatol"},{"key":"486_CR13","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1159\/000246886","volume":"189","author":"K Sayama","year":"1994","unstructured":"Sayama K, Hato N, Matsuda O et al (1994) Proteus syndrome. Dermatology 189:392\u2013395","journal-title":"Dermatology"},{"key":"486_CR14","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2106\/00004623-200201000-00013","volume":"84-A","author":"R Rivas","year":"2002","unstructured":"Rivas R, Shapiro F (2002) Structural stages in the development of the long bones and epiphyses: a study in the New Zealand white rabbit. J Bone Joint Surg Am 84-A:85\u2013100","journal-title":"J Bone Joint Surg Am"},{"key":"486_CR15","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/j.1440-1673.1990.tb02807.x","volume":"34","author":"G Nishimura","year":"1990","unstructured":"Nishimura G, Kozlowski K (1990) Proteus syndrome (report of three cases). Australas Radiol 34:47\u201352","journal-title":"Australas Radiol"},{"key":"486_CR16","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1002\/ajmg.1320270111","volume":"27","author":"RD Clark","year":"1987","unstructured":"Clark RD, Donnai D, Rogers J et al (1987) Proteus syndrome: an expanded phenotype. Am J Med Genet 27:99\u2013117","journal-title":"Am J Med Genet"},{"key":"486_CR17","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1002\/ajmg.1320470514","volume":"47","author":"MM Cohen Jr","year":"1993","unstructured":"Cohen MM Jr (1993) Proteus syndrome: clinical evidence for somatic mosaicism and selective review. Am J Med Genet 47:645\u2013652","journal-title":"Am J Med Genet"},{"key":"486_CR18","first-page":"797","volume":"13","author":"PM Bale","year":"1993","unstructured":"Bale PM, Watson G, Collins F (1993) Pathology of osseous and genitourinary lesions of Proteus syndrome. Pediatr Radiol 13:797\u2013809","journal-title":"Pediatr Radiol"},{"key":"486_CR19","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.2106\/00004623-197961070-00025","volume":"61","author":"BL Bender","year":"1979","unstructured":"Bender BL, Yunis E (1979) Fibrocartilaginous lesions of bone and hemangiomas and lipomas of soft tissue resembling Maffucci\u2019s syndrome. A case report. J Bone Joint Surg Am 61:1104\u20131108","journal-title":"J Bone Joint Surg Am"},{"key":"486_CR20","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1097\/01241398-199307000-00009","volume":"13","author":"KJ Guidera","year":"1993","unstructured":"Guidera KJ, Brinker MR, Kousseff BG et al (1993) Overgrowth management in Klippel-Trenaunay-Weber and Proteus syndromes. J Pediatr Orthop 13:459\u2013466","journal-title":"J Pediatr Orthop"},{"key":"486_CR21","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1302\/0301-620X.66B1.6693483","volume":"66","author":"RA Dickson","year":"1984","unstructured":"Dickson RA, Lawton JO, Archer IA et al (1984) The pathogenesis of idiopathic scoliosis. Biplanar spinal asymmetry. J Bone Joint Surg Br 66:8\u201315","journal-title":"J Bone Joint Surg Br"},{"key":"486_CR22","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1002\/ajmg.c.30063","volume":"137","author":"MM Cohen","year":"2005","unstructured":"Cohen MM (2005) Proteus syndrome: an update. Am J Med Genet C Semin Med Genet 137:38\u201352","journal-title":"Am J Med Genet C Semin Med Genet"}],"container-title":["Pediatric Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-007-0486-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00247-007-0486-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-007-0486-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-007-0486-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,15]],"date-time":"2022-05-15T12:10:45Z","timestamp":1652616645000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00247-007-0486-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6,14]]},"references-count":22,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2007,8]]}},"alternative-id":["486"],"URL":"https:\/\/doi.org\/10.1007\/s00247-007-0486-1","relation":{},"ISSN":["0301-0449","1432-1998"],"issn-type":[{"value":"0301-0449","type":"print"},{"value":"1432-1998","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6,14]]},"assertion":[{"value":"3 August 2006","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2006","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 January 2007","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 June 2007","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"829"}}