{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T22:30:19Z","timestamp":1789252219904,"version":"build-2803163510"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2016,5,27]],"date-time":"2016-05-27T00:00:00Z","timestamp":1464307200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Radiol"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1007\/s00247-014-3270-z","type":"journal-article","created":{"date-parts":[[2016,5,27]],"date-time":"2016-05-27T13:10:06Z","timestamp":1464354606000},"page":"963-982","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["MR spectroscopy in children: protocols and pitfalls in non-tumorous brain pathology"],"prefix":"10.1007","volume":"46","author":[{"given":"Jacques F.","family":"Schneider","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,5,27]]},"reference":[{"key":"3270_CR1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/1099-1492(200005)13:3<129::AID-NBM619>3.0.CO;2-V","volume":"13","author":"V Govindaraju","year":"2000","unstructured":"Govindaraju V, Young K, Maudsley AA (2000) Proton NMR chemical shifts and coupling constants for brain metabolites. NMR Biomed 13:129\u2013153","journal-title":"NMR Biomed"},{"key":"3270_CR2","first-page":"684","volume":"27","author":"M Inglese","year":"2006","unstructured":"Inglese M, Spindler M, Babb JS et al (2006) Field, coil, and echo-time influence on sensitivity and reproducibility of brain proton MR spectroscopy. AJNR Am J Neuroradiol 27:684\u2013688","journal-title":"AJNR Am J Neuroradiol"},{"key":"3270_CR3","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.neurad.2008.04.001","volume":"36","author":"P Jissendi Tchofo","year":"2009","unstructured":"Jissendi Tchofo P, Baleriaux D (2009) Brain (1)H-MR spectroscopy in clinical neuroimaging at 3T. J Neuroradiol 36:24\u201340","journal-title":"J Neuroradiol"},{"key":"3270_CR4","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/nbm.1940040408","volume":"4","author":"J Frahm","year":"1991","unstructured":"Frahm J, Michaelis T, Merboldt KD et al (1991) On the N-acetyl methyl resonance in localized 1H NMR spectra of human brain in vivo. NMR Biomed 4:201\u2013204","journal-title":"NMR Biomed"},{"key":"3270_CR5","first-page":"191","volume":"10","author":"B Ross","year":"1994","unstructured":"Ross B, Michaelis T (1994) Clinical applications of magnetic resonance spectroscopy. Magn Reson Q 10:191\u2013247","journal-title":"Magn Reson Q"},{"key":"3270_CR6","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/(SICI)1522-2586(200001)11:1<9::AID-JMRI2>3.0.CO;2-6","volume":"11","author":"BA Holshouser","year":"2000","unstructured":"Holshouser BA, Ashwal S, Shu S et al (2000) Proton MR spectroscopy in children with acute brain injury: comparison of short and long echo time acquisitions. J Magn Reson Imaging 11:9\u201319","journal-title":"J Magn Reson Imaging"},{"key":"3270_CR7","first-page":"895","volume":"27","author":"T Lange","year":"2006","unstructured":"Lange T, Dydak U, Roberts TP et al (2006) Pitfalls in lactate measurements at 3T. AJNR Am J Neuroradiol 27:895\u2013901","journal-title":"AJNR Am J Neuroradiol"},{"key":"3270_CR8","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1148\/radiology.188.1.8511313","volume":"188","author":"JH Duyn","year":"1993","unstructured":"Duyn JH, Gillen J, Sobering G et al (1993) Multisection proton MR spectroscopic imaging of the brain. Radiology 188:277\u2013282","journal-title":"Radiology"},{"key":"3270_CR9","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/mrm.1910050113","volume":"5","author":"RJ Ordidge","year":"1987","unstructured":"Ordidge RJ (1987) Random noise selective excitation pulses. Magn Reson Med 5:93\u201398","journal-title":"Magn Reson Med"},{"key":"3270_CR10","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/S0730-725X(98)00143-X","volume":"16","author":"PE Sijens","year":"1998","unstructured":"Sijens PE, Oudkerk M, van Dijk P et al (1998) 1H MR spectroscopy monitoring of changes in choline peak area and line shape after Gd-contrast administration. Magn Reson Imaging 16:1273\u20131280","journal-title":"Magn Reson Imaging"},{"key":"3270_CR11","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/GCO.0b013e3282f4ef9e","volume":"20","author":"AJ Gunn","year":"2008","unstructured":"Gunn AJ, Bennet L (2008) Timing of injury in the fetus and neonate. Curr Opin Obstet Gynecol 20:175\u2013181","journal-title":"Curr Opin Obstet Gynecol"},{"key":"3270_CR12","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s10140-011-0995-y","volume":"19","author":"A Ittoop","year":"2012","unstructured":"Ittoop A, Zacharia TT (2012) Imaging of neonatal brain emergencies: multisequence MRI analysis of pathologic spectrum including diffusion and MR spectroscopy. Emerg Radiol 19:149\u2013157","journal-title":"Emerg Radiol"},{"key":"3270_CR13","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1542\/peds.2004-0222","volume":"114","author":"M Rutherford","year":"2004","unstructured":"Rutherford M, Counsell S, Allsop J et al (2004) Diffusion-weighted magnetic resonance imaging in term perinatal brain injury: a comparison with site of lesion and time from birth. Pediatrics 114:1004\u20131014","journal-title":"Pediatrics"},{"key":"3270_CR14","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1542\/peds.2007-0770","volume":"121","author":"A Okereafor","year":"2008","unstructured":"Okereafor A, Allsop J, Counsell SJ et al (2008) Patterns of brain injury in neonates exposed to perinatal sentinel events. Pediatrics 121:906\u2013914","journal-title":"Pediatrics"},{"key":"3270_CR15","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S1474-4422(09)70295-9","volume":"9","author":"M Rutherford","year":"2010","unstructured":"Rutherford M, Ramenghi LA, Edwards AD et al (2010) Assessment of brain tissue injury after moderate hypothermia in neonates with hypoxic-ischaemic encephalopathy: a nested substudy of a randomised controlled trial. Lancet Neurol 9:39\u201345","journal-title":"Lancet Neurol"},{"key":"3270_CR16","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1212\/WNL.0b013e31821f442d","volume":"76","author":"M Martinez-Biarge","year":"2011","unstructured":"Martinez-Biarge M, Diez-Sebastian J, Kapellou O et al (2011) Predicting motor outcome and death in term hypoxic-ischemic encephalopathy. Neurology 76:2055\u20132061","journal-title":"Neurology"},{"key":"3270_CR17","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1007\/s00234-013-1202-5","volume":"55","author":"G Ancora","year":"2013","unstructured":"Ancora G, Testa C, Grandi S et al (2013) Prognostic value of brain proton MR spectroscopy and diffusion tensor imaging in newborns with hypoxic-ischemic encephalopathy treated by brain cooling. Neuroradiology 55:1017\u20131025","journal-title":"Neuroradiology"},{"key":"3270_CR18","first-page":"203","volume":"21","author":"Y Pu","year":"2000","unstructured":"Pu Y, Li QF, Zeng CM et al (2000) Increased detectability of alpha brain glutamate\/glutamine in neonatal hypoxic-ischemic encephalopathy. AJNR Am J Neuroradiol 21:203\u2013212","journal-title":"AJNR Am J Neuroradiol"},{"key":"3270_CR19","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1111\/j.1651-2227.1995.tb13681.x","volume":"84","author":"H Leth","year":"1995","unstructured":"Leth H, Toft PB, Pryds O et al (1995) Brain lactate in preterm and growth-retarded neonates. Acta Paediatr 84:495\u2013499","journal-title":"Acta Paediatr"},{"key":"3270_CR20","doi-asserted-by":"crossref","first-page":"e82746","DOI":"10.1371\/journal.pone.0082746","volume":"8","author":"M Tomiyasu","year":"2013","unstructured":"Tomiyasu M, Aida N, Endo M et al (2013) Neonatal brain metabolite concentrations: an in vivo magnetic resonance spectroscopy study with a clinical MR system at 3 Tesla. PLoS One 8:e82746","journal-title":"PLoS One"},{"key":"3270_CR21","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1002\/ana.410350420","volume":"35","author":"SH Graham","year":"1994","unstructured":"Graham SH, Meyerhoff DJ, Bayne L et al (1994) Magnetic resonance spectroscopy of N-acetylaspartate in hypoxic-ischemic encephalopathy. Ann Neurol 35:490\u2013494","journal-title":"Ann Neurol"},{"key":"3270_CR22","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/S0720-048X(01)00435-1","volume":"43","author":"GK Malik","year":"2002","unstructured":"Malik GK, Pandey M, Kumar R et al (2002) MR imaging and in vivo proton spectroscopy of the brain in neonates with hypoxic ischemic encephalopathy. Eur J Radiol 43:6\u201313","journal-title":"Eur J Radiol"},{"key":"3270_CR23","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1177\/08830738040190110501","volume":"19","author":"PL Khong","year":"2004","unstructured":"Khong PL, Tse C, Wong IY et al (2004) Diffusion-weighted imaging and proton magnetic resonance spectroscopy in perinatal hypoxic-ischemic encephalopathy: association with neuromotor outcome at 18 months of age. J Child Neurol 19:872\u2013881","journal-title":"J Child Neurol"},{"key":"3270_CR24","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1089\/neu.2004.21.1539","volume":"21","author":"S Ashwal","year":"2004","unstructured":"Ashwal S, Holshouser B, Tong K et al (2004) Proton MR spectroscopy detected glutamate\/glutamine is increased in children with traumatic brain injury. J Neurotrauma 21:1539\u20131552","journal-title":"J Neurotrauma"},{"key":"3270_CR25","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1203\/00006450-200207000-00014","volume":"52","author":"SP Miller","year":"2002","unstructured":"Miller SP, Newton N, Ferriero DM et al (2002) Predictors of 30-month outcome after perinatal depression: role of proton MRS and socioeconomic factors. Pediatr Res 52:71\u201377","journal-title":"Pediatr Res"},{"key":"3270_CR26","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/2046-4053-2-96","volume":"2","author":"P Degraeuwe","year":"2013","unstructured":"Degraeuwe P, Jaspers GJ, Robertson NJ et al (2013) Magnetic resonance spectroscopy as a prognostic marker in neonatal hypoxic-ischemic encephalopathy: a study protocol for an individual patient data meta-analysis. Syst Rev 2:96","journal-title":"Syst Rev"},{"key":"3270_CR27","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/RMR.0b013e318093e6c7","volume":"18","author":"A Panigrahy","year":"2007","unstructured":"Panigrahy A, Bluml S (2007) Advances in magnetic resonance neuroimaging techniques in the evaluation of neonatal encephalopathy. Top Magn Reson Imaging 18:3\u201329","journal-title":"Top Magn Reson Imaging"},{"key":"3270_CR28","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1212\/WNL.0b013e318253d589","volume":"78","author":"N Bednarek","year":"2012","unstructured":"Bednarek N, Mathur A, Inder T et al (2012) Impact of therapeutic hypothermia on MRI diffusion changes in neonatal encephalopathy. Neurology 78:1420\u20131427","journal-title":"Neurology"},{"key":"3270_CR29","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.pediatrneurol.2014.01.013","volume":"50","author":"N Rollins","year":"2014","unstructured":"Rollins N, Booth T, Morriss MC et al (2014) Predictive value of neonatal MRI showing no or minor degrees of brain injury after hypothermia. Pediatr Neurol 50:447\u2013451","journal-title":"Pediatr Neurol"},{"key":"3270_CR30","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.neulet.2010.03.066","volume":"475","author":"KW Chan","year":"2010","unstructured":"Chan KW, Chow AM, Chan KC et al (2010) Magnetic resonance spectroscopy of the brain under mild hypothermia indicates changes in neuroprotection-related metabolites. Neurosci Lett 475:150\u2013155","journal-title":"Neurosci Lett"},{"key":"3270_CR31","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1097\/SMJ.0b013e3182967d38","volume":"106","author":"NH Thakur","year":"2013","unstructured":"Thakur NH, Spencer AJ, Kilbride HW et al (2013) Findings and patterns on MRI and MR spectroscopy in neonates after therapeutic hypothermia for hypoxic ischemic encephalopathy treatment. South Med J 106:350\u2013355","journal-title":"South Med J"},{"key":"3270_CR32","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/pr.2011.8","volume":"71","author":"ET Corbo","year":"2012","unstructured":"Corbo ET, Bartnik-Olson BL, Machado S et al (2012) The effect of whole-body cooling on brain metabolism following perinatal hypoxic-ischemic injury. Pediatr Res 71:85\u201392","journal-title":"Pediatr Res"},{"key":"3270_CR33","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1203\/00006450-199604000-00004","volume":"39","author":"JD Hanrahan","year":"1996","unstructured":"Hanrahan JD, Sargentoni J, Azzopardi D et al (1996) Cerebral metabolism within 18 hours of birth asphyxia: a proton magnetic resonance spectroscopy study. Pediatr Res 39:584\u2013590","journal-title":"Pediatr Res"},{"key":"3270_CR34","first-page":"1786","volume":"22","author":"AJ Barkovich","year":"2001","unstructured":"Barkovich AJ, Westmark KD, Bedi HS et al (2001) Proton spectroscopy and diffusion imaging on the first day of life after perinatal asphyxia: preliminary report. AJNR Am J Neuroradiol 22:1786\u20131794","journal-title":"AJNR Am J Neuroradiol"},{"key":"3270_CR35","first-page":"1619","volume":"20","author":"A Bitsch","year":"1999","unstructured":"Bitsch A, Bruhn H, Vougioukas V et al (1999) Inflammatory CNS demyelination: histopathologic correlation with in vivo quantitative proton MR spectroscopy. AJNR Am J Neuroradiol 20:1619\u20131627","journal-title":"AJNR Am J Neuroradiol"},{"key":"3270_CR36","first-page":"1125","volume":"22","author":"A Bizzi","year":"2001","unstructured":"Bizzi A, Ulug AM, Crawford TO et al (2001) Quantitative proton MR spectroscopic imaging in acute disseminated encephalomyelitis. AJNR Am J Neuroradiol 22:1125\u20131130","journal-title":"AJNR Am J Neuroradiol"},{"key":"3270_CR37","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.pediatrneurol.2003.11.005","volume":"30","author":"LV Gabis","year":"2004","unstructured":"Gabis LV, Panasci DJ, Andriola MR et al (2004) Acute disseminated encephalomyelitis: an MRI\/MRS longitudinal study. Pediatr Neurol 30:324\u2013329","journal-title":"Pediatr Neurol"},{"key":"3270_CR38","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1007\/s00247-009-1372-9","volume":"40","author":"L Ben Sira","year":"2010","unstructured":"Ben Sira L, Miller E, Artzi M et al (2010) 1H-MRS for the diagnosis of acute disseminated encephalomyelitis: insight into the acute-disease stage. Pediatr Radiol 40:106\u2013113","journal-title":"Pediatr Radiol"},{"key":"3270_CR39","first-page":"1872","volume":"18","author":"RA Zimmerman","year":"1997","unstructured":"Zimmerman RA, Wang ZJ (1997) The value of proton MR spectroscopy in pediatric metabolic brain disease. AJNR Am J Neuroradiol 18:1872\u20131879","journal-title":"AJNR Am J Neuroradiol"},{"key":"3270_CR40","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S1052-5149(25)00540-4","volume":"8","author":"ZJ Wang","year":"1998","unstructured":"Wang ZJ, Zimmerman RA (1998) Proton MR spectroscopy of pediatric brain metabolic disorders. Neuroimaging Clin N Am 8:781\u2013807","journal-title":"Neuroimaging Clin N Am"},{"key":"3270_CR41","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1007\/BF00593724","volume":"37","author":"S Confort-Gouny","year":"1995","unstructured":"Confort-Gouny S, Vion-Dury J, Chabrol B et al (1995) Localised proton magnetic resonance spectroscopy in X-linked adrenoleukodystrophy. Neuroradiology 37:568\u2013575","journal-title":"Neuroradiology"},{"key":"3270_CR42","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.ymgme.2007.09.003","volume":"93","author":"N Boddaert","year":"2008","unstructured":"Boddaert N, Romano S, Funalot B et al (2008) 1H MRS spectroscopy evidence of cerebellar high lactate in mitochondrial respiratory chain deficiency. Mol Genet Metab 93:85\u201388","journal-title":"Mol Genet Metab"},{"key":"3270_CR43","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.braindev.2008.01.011","volume":"30","author":"PE Sijens","year":"2008","unstructured":"Sijens PE, Smit GP, Rodiger LA et al (2008) MR spectroscopy of the brain in Leigh syndrome. Brain Dev 30:579\u2013583","journal-title":"Brain Dev"},{"key":"3270_CR44","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1002\/ana.410290219","volume":"29","author":"JA Detre","year":"1991","unstructured":"Detre JA, Wang ZY, Bogdan AR et al (1991) Regional variation in brain lactate in Leigh syndrome by localized 1H magnetic resonance spectroscopy. Ann Neurol 29:218\u2013221","journal-title":"Ann Neurol"},{"key":"3270_CR45","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S0730-725X(99)00002-8","volume":"17","author":"ME Rubio-Gozalbo","year":"1999","unstructured":"Rubio-Gozalbo ME, Heerschap A, Trijbels JM et al (1999) Proton MR spectroscopy in a child with pyruvate dehydrogenase complex deficiency. Magn Reson Imaging 17:939\u2013944","journal-title":"Magn Reson Imaging"},{"key":"3270_CR46","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1002\/jmri.1880060609","volume":"6","author":"HJ Wittsack","year":"1996","unstructured":"Wittsack HJ, Kugel H, Roth B et al (1996) Quantitative measurements with localized 1H MR spectroscopy in children with Canavan\u2019s disease. J Magn Reson Imaging 6:889\u2013893","journal-title":"J Magn Reson Imaging"},{"key":"3270_CR47","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1055\/s-2001-12221","volume":"32","author":"JF Schneider","year":"2001","unstructured":"Schneider JF, Boltshauser E, Neuhaus TJ et al (2001) MRI and proton spectroscopy in Lowe syndrome. Neuropediatrics 32:45\u201348","journal-title":"Neuropediatrics"},{"key":"3270_CR48","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1002\/ana.102","volume":"49","author":"E Martin","year":"2001","unstructured":"Martin E, Capone A, Schneider J et al (2001) Absence of N-acetylaspartate in the human brain: impact on neurospectroscopy? Ann Neurol 49:518\u2013521","journal-title":"Ann Neurol"},{"key":"3270_CR49","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s10334-008-0137-z","volume":"21","author":"M Dezortova","year":"2008","unstructured":"Dezortova M, Jiru F, Petrasek J et al (2008) 1H MR spectroscopy as a diagnostic tool for cerebral creatine deficiency. MAGMA 21:327\u2013332","journal-title":"MAGMA"},{"key":"3270_CR50","first-page":"548","volume":"28","author":"MC Bianchi","year":"2007","unstructured":"Bianchi MC, Tosetti M, Battini R et al (2007) Treatment monitoring of brain creatine deficiency syndromes: a 1H- and 31P-MR spectroscopy study. AJNR Am J Neuroradiol 28:548\u2013554","journal-title":"AJNR Am J Neuroradiol"},{"key":"3270_CR51","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.ajhg.2009.08.005","volume":"85","author":"R Steinfeld","year":"2009","unstructured":"Steinfeld R, Grapp M, Kraetzner R et al (2009) Folate receptor alpha defect causes cerebral folate transport deficiency: a treatable neurodegenerative disorder associated with disturbed myelin metabolism. Am J Hum Genet 85:354\u2013363","journal-title":"Am J Hum Genet"},{"key":"3270_CR52","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.ymgme.2011.05.019","volume":"104","author":"P Dill","year":"2011","unstructured":"Dill P, Schneider J, Weber P et al (2011) Pyridoxal phosphate-responsive seizures in a patient with cerebral folate deficiency (CFD) and congenital deafness with labyrinthine aplasia, microtia and microdontia (LAMM). Mol Genet Metab 104:362\u2013368","journal-title":"Mol Genet Metab"},{"key":"3270_CR53","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1096\/fj.02-0456fje","volume":"17","author":"BC Schwahn","year":"2003","unstructured":"Schwahn BC, Chen Z, Laryea MD et al (2003) Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency. FASEB J 17:512\u2013514","journal-title":"FASEB J"},{"key":"3270_CR54","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/ana.10246","volume":"52","author":"A Bizzi","year":"2002","unstructured":"Bizzi A, Bugiani M, Salomons GS et al (2002) X-linked creatine deficiency syndrome: a novel mutation in creatine transporter gene SLC6A8. Ann Neurol 52:227\u2013231","journal-title":"Ann Neurol"},{"key":"3270_CR55","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s00234-003-0955-7","volume":"45","author":"W Jan","year":"2003","unstructured":"Jan W, Zimmerman RA, Wang ZJ et al (2003) MR diffusion imaging and MR spectroscopy of maple syrup urine disease during acute metabolic decompensation. Neuroradiology 45:393\u2013399","journal-title":"Neuroradiology"},{"key":"3270_CR56","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1002\/ana.410330412","volume":"33","author":"SR Felber","year":"1993","unstructured":"Felber SR, Sperl W, Chemelli A et al (1993) Maple syrup urine disease: metabolic decompensation monitored by proton magnetic resonance imaging and spectroscopy. Ann Neurol 33:396\u2013401","journal-title":"Ann Neurol"},{"key":"3270_CR57","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/j.1468-1331.2009.02867.x","volume":"17","author":"KH Chang","year":"2010","unstructured":"Chang KH, Tsou JC, Chen ST et al (2010) Temporal features of magnetic resonance imaging and spectroscopy in non-ketotic hyperglycemic chorea-ballism patients. Eur J Neurol 17:589\u2013593","journal-title":"Eur J Neurol"},{"key":"3270_CR58","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1001\/archneur.64.5.659","volume":"64","author":"F Eichler","year":"2007","unstructured":"Eichler F, Mahmood A, Loes D et al (2007) Magnetic resonance imaging detection of lesion progression in adult patients with X-linked adrenoleukodystrophy. Arch Neurol 64:659\u2013664","journal-title":"Arch Neurol"},{"key":"3270_CR59","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1212\/WNL.58.6.901","volume":"58","author":"FS Eichler","year":"2002","unstructured":"Eichler FS, Barker PB, Cox C et al (2002) Proton MR spectroscopic imaging predicts lesion progression on MRI in X-linked adrenoleukodystrophy. Neurology 58:901\u2013907","journal-title":"Neurology"}],"container-title":["Pediatric Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-014-3270-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00247-014-3270-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-014-3270-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T19:48:15Z","timestamp":1748980095000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00247-014-3270-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,27]]},"references-count":59,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["3270"],"URL":"https:\/\/doi.org\/10.1007\/s00247-014-3270-z","relation":{},"ISSN":["0301-0449","1432-1998"],"issn-type":[{"value":"0301-0449","type":"print"},{"value":"1432-1998","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,27]]}}}