{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T10:10:36Z","timestamp":1780913436984,"version":"3.54.1"},"reference-count":90,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2018,1,23]],"date-time":"2018-01-23T00:00:00Z","timestamp":1516665600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Radiol"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1007\/s00247-018-4068-1","type":"journal-article","created":{"date-parts":[[2018,1,23]],"date-time":"2018-01-23T13:01:55Z","timestamp":1516712515000},"page":"555-564","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Role of interventional radiology in managing pediatric liver tumors"],"prefix":"10.1007","volume":"48","author":[{"given":"Matthew P.","family":"Lungren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander J.","family":"Towbin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek J.","family":"Roebuck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric J.","family":"Monroe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne E.","family":"Gill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avnesh","family":"Thakor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard B.","family":"Towbin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Marie","family":"Cahill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Matthew Hawkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,1,23]]},"reference":[{"key":"4068_CR1","doi-asserted-by":"crossref","first-page":"S136","DOI":"10.1016\/S0168-8278(02)00432-4","volume":"38","author":"JM Llovet","year":"2003","unstructured":"Llovet JM, Beaugrand M (2003) Hepatocellular carcinoma: present status and future prospects. J Hepatol 38:S136\u2013S149","journal-title":"J Hepatol"},{"key":"4068_CR2","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/S1470-2045(04)01527-X","volume":"5","author":"JW Marsh","year":"2004","unstructured":"Marsh JW, Geller DA, Finkelstein SD et al (2004) Role of liver transplantation for hepatobiliary malignant disorders. Lancet Oncol 5:480\u2013488","journal-title":"Lancet Oncol"},{"key":"4068_CR3","doi-asserted-by":"crossref","first-page":"2789","DOI":"10.1200\/JCO.2002.06.155","volume":"20","author":"HM Katzenstein","year":"2002","unstructured":"Katzenstein HM, Krailo MD, Malogolowkin MH et al (2002) Hepatocellular carcinoma in children and adolescents: results from the pediatric oncology group and the Children's cancer group intergroup study. J Clin Oncol 20:2789\u20132797","journal-title":"J Clin Oncol"},{"key":"4068_CR4","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.surg.2012.11.006","volume":"153","author":"RJ Cruz Jr","year":"2013","unstructured":"Cruz RJ Jr, Ranganathan S, Mazariegos G et al (2013) Analysis of national and single-center incidence and survival after liver transplantation for hepatoblastoma: new trends and future opportunities. Surgery 153:150\u2013159","journal-title":"Surgery"},{"key":"4068_CR5","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1111\/j.1399-3046.2009.01062.x","volume":"13","author":"H Ismail","year":"2009","unstructured":"Ismail H, Broniszczak D, Kalicinski P et al (2009) Liver transplantation in children with hepatocellular carcinoma. Do Milan criteria apply to pediatric patients? Pediatr Transplant 13:682\u2013692","journal-title":"Pediatr Transplant"},{"key":"4068_CR6","first-page":"S259","volume":"20","author":"PJ Kalicinski","year":"2014","unstructured":"Kalicinski PJ, Ismail H, Broniszczak D et al (2014) Primary malignant hepatic tumors as indication for liver transplantation in children \u2014 20 years experience. Liver Transplant 20:S259","journal-title":"Liver Transplant"},{"key":"4068_CR7","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/j.1399-3046.2007.00751.x","volume":"11","author":"M Beaunoyer","year":"2007","unstructured":"Beaunoyer M, Vanatta JM, Ogihara M et al (2007) Outcomes of transplantation in children with primary hepatic malignancy. Pediatr Transplant 11:655\u2013660","journal-title":"Pediatr Transplant"},{"key":"4068_CR8","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1002\/1097-0142(19870801)60:3<414::AID-CNCR2820600322>3.0.CO;2-S","volume":"60","author":"CR Depotter","year":"1987","unstructured":"Depotter CR, Robberecht E, Laureys G et al (1987) Hepatitis-B related childhood hepatocellular-carcinoma \u2014 childhood hepatic malignancies. Cancer 60:414\u2013418","journal-title":"Cancer"},{"key":"4068_CR9","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1002\/mpo.10178","volume":"39","author":"P Czauderna","year":"2002","unstructured":"Czauderna P (2002) Adult type vs. childhood hepatocellular carcinoma \u2014 are they the same or different lesions? Biology, natural history, prognosis, and treatment. Med Pediatr Oncol 39:519\u2013523","journal-title":"Med Pediatr Oncol"},{"key":"4068_CR10","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.jpedsurg.2013.09.050","volume":"49","author":"BJ Allan","year":"2014","unstructured":"Allan BJ, Wang B, Davis JS et al (2014) A review of 218 pediatric cases of hepatocellular carcinoma. J Pediatr Surg 49:166\u2013171","journal-title":"J Pediatr Surg"},{"key":"4068_CR11","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1034\/j.1600-0676.2000.020002173.x","volume":"20","author":"H Kim","year":"2000","unstructured":"Kim H, Lee MJ, Kim MR et al (2000) Expression of cyclin D1, cyclin E, cdk4 and loss of heterozygosity of 8p, 13q, 17p in hepatocellular carcinoma: comparison study of childhood and adult hepatocellular carcinoma. Liver 20:173\u2013178","journal-title":"Liver"},{"key":"4068_CR12","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.gtc.2017.01.009","volume":"46","author":"MS Torbenson","year":"2017","unstructured":"Torbenson MS (2017) Morphologic subtypes of hepatocellular carcinoma. Gastroenterol Clin N Am 46:365\u2013391","journal-title":"Gastroenterol Clin N Am"},{"key":"4068_CR13","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1007\/s00247-012-2366-6","volume":"42","author":"AB Meyers","year":"2012","unstructured":"Meyers AB, Towbin AJ, Geller JI et al (2012) Hepatoblastoma imaging with gadoxetate disodium-enhanced MRI \u2014 typical, atypical, pre- and post-treatment evaluation. Pediatr Radiol 42:859\u2013866","journal-title":"Pediatr Radiol"},{"key":"4068_CR14","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1007\/s00247-016-3612-0","volume":"46","author":"BS Pugmire","year":"2016","unstructured":"Pugmire BS, Towbin AJ (2016) Magnetic resonance imaging of primary pediatric liver tumors. Pediatr Radiol 46:764\u2013777","journal-title":"Pediatr Radiol"},{"key":"4068_CR15","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s00247-006-0361-5","volume":"37","author":"DJ Roebuck","year":"2007","unstructured":"Roebuck DJ, Aronson D, Clapuyt P et al (2007) 2005 PRETEXT: a revised staging system for primary malignant liver tumours of childhood developed by the SIOPEL group. Pediatr Radiol 37:123\u2013132","journal-title":"Pediatr Radiol"},{"key":"4068_CR16","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1097\/SLA.0000000000001936","volume":"266","author":"J Fuchs","year":"2016","unstructured":"Fuchs J, Cavdar S, Blumenstock G et al (2016) POST-TEXT III and IV hepatoblastoma: extended hepatic resection avoids liver transplantation in selected cases. Ann Surg 266:318\u2013323","journal-title":"Ann Surg"},{"key":"4068_CR17","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jpedsurg.2013.11.029","volume":"49","author":"MP Quaglia La","year":"2014","unstructured":"La Quaglia MP (2014) State of the art in oncology: high risk neuroblastoma, alveolar rhabdomyosarcoma, desmoplastic small round cell tumor, and POST-TEXT 3 and 4 hepatoblastoma. J Pediatr Surg 49:233\u2013240","journal-title":"J Pediatr Surg"},{"key":"4068_CR18","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1002\/cncr.25722","volume":"117","author":"TB Lautz","year":"2011","unstructured":"Lautz TB, Ben-Ami T, Tantemsapya N et al (2011) Successful nontransplant resection of POST-TEXT III and IV hepatoblastoma. Cancer 117:1976\u20131983","journal-title":"Cancer"},{"key":"4068_CR19","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.cld.2015.01.010","volume":"19","author":"D Kelly","year":"2015","unstructured":"Kelly D, Sharif K, Brown RM et al (2015) Hepatocellular carcinoma in children. Clin Liver Dis 19:433\u2013447","journal-title":"Clin Liver Dis"},{"key":"4068_CR20","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1200\/JCO.2014.60.2250","volume":"34","author":"M Murawski","year":"2016","unstructured":"Murawski M, Weeda VB, Maibach R et al (2016) Hepatocellular carcinoma in children: does modified platinum- and doxorubicin-based chemotherapy increase tumor resectability and change outcome? Lessons learned from the SIOPEL 2 and 3 studies. J Clin Oncol 34:1050\u20131056","journal-title":"J Clin Oncol"},{"key":"4068_CR21","doi-asserted-by":"crossref","first-page":"2798","DOI":"10.1200\/JCO.2002.06.102","volume":"20","author":"P Czauderna","year":"2002","unstructured":"Czauderna P, Mackinlay G, Perilongo G et al (2002) Hepatocellular carcinoma in children: results of the first prospective study of the International Society of Pediatric Oncology group. J Clin Oncol 20:2798\u20132804","journal-title":"J Clin Oncol"},{"key":"4068_CR22","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1001\/jamasurg.2015.1847","volume":"150","author":"TA Pham","year":"2015","unstructured":"Pham TA, Gallo AM, Concepcion W et al (2015) Effect of liver transplant on long-term disease-free survival in children with hepatoblastoma and hepatocellular cancer. JAMA Surg 150:1150\u20131158","journal-title":"JAMA Surg"},{"key":"4068_CR23","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/jnci\/92.3.205","volume":"92","author":"P Therasse","year":"2000","unstructured":"Therasse P, Arbuck SG, Eisenhauer EA et al (2000) New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92:205\u2013216","journal-title":"J Natl Cancer Inst"},{"key":"4068_CR24","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0168-8278(01)00130-1","volume":"35","author":"J Bruix","year":"2001","unstructured":"Bruix J, Sherman M, Llovet JM et al (2001) Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the liver. J Hepatol 35:421\u2013430","journal-title":"J Hepatol"},{"key":"4068_CR25","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1056\/NEJMoa0708857","volume":"359","author":"JM Llovet","year":"2008","unstructured":"Llovet JM, Ricci S, Mazzaferro V et al (2008) Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 359:378\u2013390","journal-title":"N Engl J Med"},{"key":"4068_CR26","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1002\/cncr.24050","volume":"115","author":"A Forner","year":"2009","unstructured":"Forner A, Ayuso C, Varela M et al (2009) Evaluation of tumor response after locoregional therapies in hepatocellular carcinoma: are response evaluation criteria in solid tumors reliable? Cancer 115:616\u2013623","journal-title":"Cancer"},{"key":"4068_CR27","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1002\/hep.20933","volume":"42","author":"J Bruix","year":"2005","unstructured":"Bruix J, Sherman M, Practice Guidelines Committee, American Association for the Study of Liver Diseases (2005) Management of hepatocellular carcinoma. Hepatology 42:1208\u20131236","journal-title":"Hepatology"},{"key":"4068_CR28","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1093\/jnci\/djn134","volume":"100","author":"JM Llovet","year":"2008","unstructured":"Llovet JM, Di Bisceglie AM, Bruix J et al (2008) Design and endpoints of clinical trials in hepatocellular carcinoma. J Natl Cancer Inst 100:698\u2013711","journal-title":"J Natl Cancer Inst"},{"key":"4068_CR29","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/j.jhep.2017.01.012","volume":"66","author":"R Lencioni","year":"2017","unstructured":"Lencioni R, Montal R, Torres F et al (2017) Objective response by mRECIST as a predictor and potential surrogate end point of overall survival in advanced HCC. J Hepatol 66:1166\u20131172","journal-title":"J Hepatol"},{"key":"4068_CR30","volume":"2016","author":"JW As van","year":"2016","unstructured":"van As JW, van den Berg H, van Dalen EC (2016) Platinum-induced hearing loss after treatment for childhood cancer. Cochrane Database Syst Rev 2016:CD010181","journal-title":"Cochrane Database Syst Rev"},{"key":"4068_CR31","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S1470-2045(16)30625-8","volume":"18","author":"DR Freyer","year":"2017","unstructured":"Freyer DR, Chen L, Krailo MD et al (2017) Effects of sodium thiosulfate versus observation on development of cisplatin-induced hearing loss in children with cancer (ACCL0431): a multicentre, randomised, controlled, open-label, phase 3 trial. Lancet Oncol 18:63\u201374","journal-title":"Lancet Oncol"},{"key":"4068_CR32","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/S1470-2045(16)30598-8","volume":"18","author":"RL Meyers","year":"2017","unstructured":"Meyers RL, Maibach R, Hiyama E et al (2017) Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic Tumors International Collaboration. Lancet Oncol 18:122\u2013131","journal-title":"Lancet Oncol"},{"key":"4068_CR33","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1111\/petr.12144","volume":"17","author":"JP McAteer","year":"2013","unstructured":"McAteer JP, Goldin AB, Healey PJ et al (2013) Surgical treatment of primary liver tumors in children: outcomes analysis of resection and transplantation in the SEER database. Pediatr Transplant 17:744\u2013750","journal-title":"Pediatr Transplant"},{"key":"4068_CR34","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/S1470-2045(13)70272-9","volume":"14","author":"J Zsiros","year":"2013","unstructured":"Zsiros J, Brugieres L, Brock P et al (2013) Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study. Lancet Oncol 14:834\u2013842","journal-title":"Lancet Oncol"},{"key":"4068_CR35","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1200\/JCO.2009.22.4857","volume":"28","author":"J Zsiros","year":"2010","unstructured":"Zsiros J, Maibach R, Shafford E et al (2010) Successful treatment of childhood high-risk hepatoblastoma with dose-intensive multiagent chemotherapy and surgery: final results of the SIOPEL-3HR study. J Clin Oncol 28:2584\u20132590","journal-title":"J Clin Oncol"},{"key":"4068_CR36","first-page":"37","volume":"13","author":"P Kalicinski","year":"2008","unstructured":"Kalicinski P, Ismail H, Broniszczak D et al (2008) Non-resectable hepatic tumors in children \u2014 role of liver transplantation. Ann Transplant 13:37\u201341","journal-title":"Ann Transplant"},{"key":"4068_CR37","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1111\/petr.12160","volume":"17","author":"JB Otte","year":"2013","unstructured":"Otte JB, Meyers RL, de Ville de Goyet J (2013) Transplantation for liver tumors in children: time to (re)set the guidelines? Pediatr Transplant 17:710\u2013712","journal-title":"Pediatr Transplant"},{"key":"4068_CR38","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1016\/j.jpedsurg.2009.06.003","volume":"44","author":"AC Tannuri","year":"2009","unstructured":"Tannuri AC, Tannuri U, Gibelli NE et al (2009) Surgical treatment of hepatic tumors in children: lessons learned from liver transplantation. J Pediatr Surg 44:2083\u20132087","journal-title":"J Pediatr Surg"},{"key":"4068_CR39","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00595-003-2663-7","volume":"34","author":"Y Ohtsuka","year":"2004","unstructured":"Ohtsuka Y, Matsunaga T, Yoshida H et al (2004) Optimal strategy of preoperative transcatheter arterial chemoembolization for hepatoblastoma. Surg Today 34:127\u2013133","journal-title":"Surg Today"},{"key":"4068_CR40","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1093\/ajcp\/100.3.270","volume":"100","author":"DC Farhi","year":"1993","unstructured":"Farhi DC, Odell CA, Shurin SB (1993) Myelodysplastic syndrome and acute myeloid leukemia after treatment for solid tumors of childhood. Am J Clin Pathol 100:270\u2013275","journal-title":"Am J Clin Pathol"},{"key":"4068_CR41","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0720-048X(00)00291-6","volume":"37","author":"J Moppett","year":"2001","unstructured":"Moppett J, Oakhill A, Duncan AW (2001) Second malignancies in children: the usual suspects? Eur J Radiol 37:95\u2013108","journal-title":"Eur J Radiol"},{"key":"4068_CR42","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1097\/00008480-199606000-00016","volume":"8","author":"JD Geiger","year":"1996","unstructured":"Geiger JD (1996) Surgery for hepatoblastoma in children. Curr Opin Pediatr 8:276\u2013282","journal-title":"Curr Opin Pediatr"},{"key":"4068_CR43","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/j.jvir.2013.04.023","volume":"24","author":"R Hickey","year":"2013","unstructured":"Hickey R, Vouche M, Sze DY et al (2013) Cancer concepts and principles: primer for the interventional oncologist-part II. J Vasc Interv Radiol 24:1167\u20131188","journal-title":"J Vasc Interv Radiol"},{"key":"4068_CR44","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s00270-006-0062-3","volume":"30","author":"L Marelli","year":"2007","unstructured":"Marelli L, Stigliano R, Triantos C et al (2007) Transarterial therapy for hepatocellular carcinoma: which technique is more effective? A systematic review of cohort and randomized studies. Cardiovasc Intervent Radiol 30:6\u201325","journal-title":"Cardiovasc Intervent Radiol"},{"key":"4068_CR45","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1053\/j.gastro.2009.09.006","volume":"138","author":"R Salem","year":"2010","unstructured":"Salem R, Lewandowski RJ, Mulcahy MF et al (2010) Radioembolization for hepatocellular carcinoma using yttrium-90 microspheres: a comprehensive report of long-term outcomes. Gastroenterology 138:52\u201364","journal-title":"Gastroenterology"},{"key":"4068_CR46","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4419-5856-3","volume-title":"Pediatric interventional radiology handbook of vascular and non-vascular interventions","author":"M Temple","year":"2014","unstructured":"Temple M, Marshalleck FE (2014) Pediatric interventional radiology handbook of vascular and non-vascular interventions. Springer Science + Business Media, New York"},{"key":"4068_CR47","doi-asserted-by":"crossref","first-page":"3069","DOI":"10.3748\/wjg.v20.i12.3069","volume":"20","author":"EA Tsochatzis","year":"2014","unstructured":"Tsochatzis EA, Fatourou E, O'Beirne J et al (2014) Transarterial chemoembolization and bland embolization for hepatocellular carcinoma. World J Gastroenterol 20:3069\u20133077","journal-title":"World J Gastroenterol"},{"key":"4068_CR48","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.jhep.2010.01.031","volume":"53","author":"E Tsochatzis","year":"2010","unstructured":"Tsochatzis E, Meyer T, Marelli L et al (2010) Which transarterial therapy is best for hepatocellular carcinoma? \u2014 the evidence to date. J Hepatol 53:588","journal-title":"J Hepatol"},{"key":"4068_CR49","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/s11912-017-0597-2","volume":"19","author":"S Kishore","year":"2017","unstructured":"Kishore S, Friedman T, Madoff DC (2017) Update on embolization therapies for hepatocellular carcinoma. Curr Oncol Rep 19:40","journal-title":"Curr Oncol Rep"},{"key":"4068_CR50","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1002\/pbc.20422","volume":"46","author":"P Czauderna","year":"2006","unstructured":"Czauderna P, Zbrzezniak G, Narozanski W et al (2006) Preliminary experience with arterial chemoembolization for hepatoblastoma and hepatocellular carcinoma in children. Pediatr Blood Cancer 46:825\u2013828","journal-title":"Pediatr Blood Cancer"},{"key":"4068_CR51","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1148\/radiol.10101058","volume":"258","author":"GE Chung","year":"2011","unstructured":"Chung GE, Lee JH, Kim HY et al (2011) Transarterial chemoembolization can be safely performed in patients with hepatocellular carcinoma invading the main portal vein and may improve the overall survival. Radiology 258:627\u2013634","journal-title":"Radiology"},{"key":"4068_CR52","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/1471-230X-13-60","volume":"13","author":"TC Xue","year":"2013","unstructured":"Xue TC, Xie XY, Zhang L et al (2013) Transarterial chemoembolization for hepatocellular carcinoma with portal vein tumor thrombus: a meta-analysis. BMC Gastroenterol 13:60","journal-title":"BMC Gastroenterol"},{"key":"4068_CR53","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1097\/01.RVI.0000182160.26798.A2","volume":"16","author":"DB Brown","year":"2005","unstructured":"Brown DB, Pilgram TK, Darcy MD et al (2005) Hepatic arterial chemoembolization for hepatocellular carcinoma: comparison of survival rates with different embolic agents. J Vasc Interv Radiol 16:1661\u20131666","journal-title":"J Vasc Interv Radiol"},{"key":"4068_CR54","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1148\/radiology.148.2.6306721","volume":"148","author":"R Yamada","year":"1983","unstructured":"Yamada R, Sato M, Kawabata M et al (1983) Hepatic artery embolization in 120 patients with unresectable hepatoma. Radiology 148:397\u2013401","journal-title":"Radiology"},{"key":"4068_CR55","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1148\/radiology.170.3.2536946","volume":"170","author":"H Nakamura","year":"1989","unstructured":"Nakamura H, Hashimoto T, Oi H et al (1989) Transcatheter oily chemoembolization of hepatocellular carcinoma. Radiology 170:783\u2013786","journal-title":"Radiology"},{"key":"4068_CR56","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1159\/000367739","volume":"4","author":"M Tsurusaki","year":"2015","unstructured":"Tsurusaki M, Murakami T (2015) Surgical and locoregional therapy of HCC: TACE. Liver Cancer 4:165\u2013175","journal-title":"Liver Cancer"},{"key":"4068_CR57","doi-asserted-by":"crossref","first-page":"8451","DOI":"10.1007\/s13277-014-2340-z","volume":"35","author":"ZB Xie","year":"2014","unstructured":"Xie ZB, Ma L, Wang XB et al (2014) Transarterial embolization with or without chemotherapy for advanced hepatocellular carcinoma: a systematic review. Tumour Biol 35:8451\u20138459","journal-title":"Tumour Biol"},{"key":"4068_CR58","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1002\/cncr.24884","volume":"116","author":"BI Carr","year":"2010","unstructured":"Carr BI, Kondragunta V, Buch SC et al (2010) Therapeutic equivalence in survival for hepatic arterial chemoembolization and yttrium 90 microsphere treatments in unresectable hepatocellular carcinoma: a two-cohort study. Cancer 116:1305\u20131314","journal-title":"Cancer"},{"key":"4068_CR59","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/j.ejca.2012.11.012","volume":"49","author":"E Tsochatzis","year":"2013","unstructured":"Tsochatzis E, Meyer T, O'Beirne J, Burroughs AK (2013) Transarterial chemoembolisation is not superior to embolisation alone: the recent European Association for the Study of the liver (EASL) \u2014 European Organization for Research and Treatment of cancer (EORTC) guidelines. Eur J Cancer 49:1509\u20131510","journal-title":"Eur J Cancer"},{"key":"4068_CR60","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.jhep.2011.12.001","volume":"56","author":"European Association for the Study of the Liver, European Organisation for Research and the Treatment of Cancer","year":"2012","unstructured":"European Association for the Study of the Liver, European Organisation for Research and the Treatment of Cancer (2012) EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. J Hepatol 56:908\u2013943","journal-title":"J Hepatol"},{"key":"4068_CR61","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/hep.24199","volume":"53","author":"J Bruix","year":"2011","unstructured":"Bruix J, Sherman M, American Association for the Study of Liver Diseases (2011) Management of hepatocellular carcinoma: an update. Hepatology 53:1020\u20131022","journal-title":"Hepatology"},{"key":"4068_CR62","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/liv.12270","volume":"34","author":"CJ Kim","year":"2014","unstructured":"Kim CJ, Kim HJ, Park JH et al (2014) Radiologic response to transcatheter hepatic arterial chemoembolization and clinical outcomes in patients with hepatocellular carcinoma. Liver Int 34:305\u2013312","journal-title":"Liver Int"},{"key":"4068_CR63","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s00270-009-9750-0","volume":"33","author":"K Malagari","year":"2010","unstructured":"Malagari K, Pomoni M, Kelekis A et al (2010) Prospective randomized comparison of chemoembolization with doxorubicin-eluting beads and bland embolization with BeadBlock for hepatocellular carcinoma. Cardiovasc Intervent Radiol 33:541\u2013551","journal-title":"Cardiovasc Intervent Radiol"},{"key":"4068_CR64","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.4254\/wjh.v7.i16.2009","volume":"7","author":"A Facciorusso","year":"2015","unstructured":"Facciorusso A, Licinio R, Muscatiello N et al (2015) Transarterial chemoembolization: evidences from the literature and applications in hepatocellular carcinoma patients. World J Hepatol 7:2009\u20132019","journal-title":"World J Hepatol"},{"key":"4068_CR65","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1016\/S0140-6736(02)08649-X","volume":"359","author":"JM Llovet","year":"2002","unstructured":"Llovet JM, Real MI, Montana X et al (2002) Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial. Lancet 359:1734\u20131739","journal-title":"Lancet"},{"key":"4068_CR66","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1053\/jhep.2002.33156","volume":"35","author":"CM Lo","year":"2002","unstructured":"Lo CM, Ngan H, Tso WK et al (2002) Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma. Hepatology 35:1164\u20131171","journal-title":"Hepatology"},{"key":"4068_CR67","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1399-0012.2004.00164.x","volume":"18","author":"LL Wong","year":"2004","unstructured":"Wong LL, Tanaka K, Lau L et al (2004) Pre-transplant treatment of hepatocellular carcinoma: assessment of tumor necrosis in explanted livers. Clin Transpl 18:227\u2013234","journal-title":"Clin Transpl"},{"key":"4068_CR68","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1053\/jlts.2003.50106","volume":"9","author":"IW Graziadei","year":"2003","unstructured":"Graziadei IW, Sandmueller H, Waldenberger P et al (2003) Chemoembolization followed by liver transplantation for hepatocellular carcinoma impedes tumor progression while on the waiting list and leads to excellent outcome. Liver Transpl 9:557\u2013563","journal-title":"Liver Transpl"},{"key":"4068_CR69","doi-asserted-by":"crossref","first-page":"708","DOI":"10.2214\/ajr.181.3.1810708","volume":"181","author":"IR Kamel","year":"2003","unstructured":"Kamel IR, Bluemke DA, Ramsey D et al (2003) Role of diffusion-weighted imaging in estimating tumor necrosis after chemoembolization of hepatocellular carcinoma. AJR Am J Roentgenol 181:708\u2013710","journal-title":"AJR Am J Roentgenol"},{"key":"4068_CR70","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s12032-017-0917-2","volume":"34","author":"F Pesapane","year":"2017","unstructured":"Pesapane F, Nezami N, Patella F et al (2017) New concepts in embolotherapy of HCC. Med Oncol 34:58","journal-title":"Med Oncol"},{"key":"4068_CR71","doi-asserted-by":"crossref","first-page":"2644","DOI":"10.1111\/j.1600-6143.2006.01509.x","volume":"6","author":"M Lesurtel","year":"2006","unstructured":"Lesurtel M, Mullhaupt B, Pestalozzi BC et al (2006) Transarterial chemoembolization as a bridge to liver transplantation for hepatocellular carcinoma: an evidence-based analysis. Am J Transplant 6:2644\u20132650","journal-title":"Am J Transplant"},{"key":"4068_CR72","doi-asserted-by":"crossref","first-page":"658","DOI":"10.3748\/wjg.v8.i4.658","volume":"8","author":"FH Yan","year":"2002","unstructured":"Yan FH, Zhou KR, Cheng JM et al (2002) Role and limitation of FMPSPGR dynamic contrast scanning in the follow-up of patients with hepatocellular carcinoma treated by TACE. World J Gastroenterol 8:658\u2013662","journal-title":"World J Gastroenterol"},{"key":"4068_CR73","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1002\/hep.510270617","volume":"27","author":"J Bruix","year":"1998","unstructured":"Bruix J, Llovet JM, Castells A et al (1998) Transarterial embolization versus symptomatic treatment in patients with advanced hepatocellular carcinoma: results of a randomized, controlled trial in a single institution. Hepatology 27:1578\u20131583","journal-title":"Hepatology"},{"key":"4068_CR74","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1053\/jhep.2003.50047","volume":"37","author":"JM Llovet","year":"2003","unstructured":"Llovet JM, Bruix J (2003) Systematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survival. Hepatology 37:429\u2013442","journal-title":"Hepatology"},{"key":"4068_CR75","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1097\/SLA.0b013e31818a07d4","volume":"248","author":"WC Chapman","year":"2008","unstructured":"Chapman WC, Majella Doyle MB, Stuart JE et al (2008) Outcomes of neoadjuvant transarterial chemoembolization to downstage hepatocellular carcinoma before liver transplantation. Ann Surg 248:617\u2013625","journal-title":"Ann Surg"},{"key":"4068_CR76","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1097\/00000658-200204000-00012","volume":"235","author":"S Roayaie","year":"2002","unstructured":"Roayaie S, Frischer JS, Emre SH et al (2002) Long-term results with multimodal adjuvant therapy and liver transplantation for the treatment of hepatocellular carcinomas larger than 5 centimeters. Ann Surg 235:533\u2013539","journal-title":"Ann Surg"},{"key":"4068_CR77","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1111\/j.1600-6143.2009.02576.x","volume":"9","author":"W Luna De","year":"2009","unstructured":"De Luna W, Sze DY, Ahmed A et al (2009) Transarterial chemoinfusion for hepatocellular carcinoma as downstaging therapy and a bridge toward liver transplantation. Am J Transplant 9:1158\u20131168","journal-title":"Am J Transplant"},{"key":"4068_CR78","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1097\/00005176-200002000-00009","volume":"30","author":"DA Gerber","year":"2000","unstructured":"Gerber DA, Arcement C, Carr B et al (2000) Use of intrahepatic chemotherapy to treat advanced pediatric hepatic malignancies. J Pediatr Gastr Nutr 30:137\u2013144","journal-title":"J Pediatr Gastr Nutr"},{"key":"4068_CR79","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s002470000296","volume":"30","author":"CM Arcement","year":"2000","unstructured":"Arcement CM, Towbin RB, Meza MP et al (2000) Intrahepatic chemoembolization in unresectable pediatric liver malignancies. Pediatr Radiol 30:779\u2013785","journal-title":"Pediatr Radiol"},{"key":"4068_CR80","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1200\/JCO.2000.18.6.1279","volume":"18","author":"MH Malogolowkin","year":"2000","unstructured":"Malogolowkin MH, Stanley P, Steele DA et al (2000) Feasibility and toxicity of chemoembolization for children with liver tumors. J Clin Oncol 18:1279\u20131284","journal-title":"J Clin Oncol"},{"key":"4068_CR81","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1016\/j.ijrobp.2004.09.004","volume":"60","author":"AS Kennedy","year":"2004","unstructured":"Kennedy AS, Nutting C, Coldwell D et al (2004) Pathologic response and microdosimetry of (90)Y microspheres in man: review of four explanted whole livers. Int J Radiat Oncol Biol Phys 60:1552\u20131563","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"4068_CR82","doi-asserted-by":"crossref","first-page":"403","DOI":"10.2214\/ajr.172.2.9930792","volume":"172","author":"JH Chen","year":"1999","unstructured":"Chen JH, Chai JW, Huang CL et al (1999) Proximal arterioportal shunting associated with hepatocellular carcinoma: features revealed by dynamic helical CT. AJR Am J Roentgenol 172:403\u2013407","journal-title":"AJR Am J Roentgenol"},{"key":"4068_CR83","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1007\/BF01084369","volume":"23","author":"S Ho","year":"1996","unstructured":"Ho S, Lau WY, Leung TW et al (1996) Partition model for estimating radiation doses from yttrium-90 microspheres in treating hepatic tumours. Eur J Nucl Med 23:947\u2013952","journal-title":"Eur J Nucl Med"},{"key":"4068_CR84","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1097\/01.RVI.0000164324.79242.B2","volume":"16","author":"DM Liu","year":"2005","unstructured":"Liu DM, Salem R, Bui JT et al (2005) Angiographic considerations in patients undergoing liver-directed therapy. J Vasc Interv Radiol 16:911\u2013935","journal-title":"J Vasc Interv Radiol"},{"key":"4068_CR85","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1148\/radiol.11081489","volume":"259","author":"RJ Lewandowski","year":"2011","unstructured":"Lewandowski RJ, Geschwind JF, Liapi E et al (2011) Transcatheter intraarterial therapies: rationale and overview. Radiology 259:641\u2013657","journal-title":"Radiology"},{"key":"4068_CR86","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1053\/j.gastro.2010.10.049","volume":"140","author":"R Salem","year":"2011","unstructured":"Salem R, Lewandowski RJ, Kulik L et al (2011) Radioembolization results in longer time-to-progression and reduced toxicity compared with chemoembolization in patients with hepatocellular carcinoma. Gastroenterology 140:497\u2013507","journal-title":"Gastroenterology"},{"key":"4068_CR87","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1007\/s00247-012-2568-y","volume":"43","author":"CM Hawkins","year":"2013","unstructured":"Hawkins CM, Kukreja K, Geller JI et al (2013) Radioembolisation for treatment of pediatric hepatocellular carcinoma. Pediatr Radiol 43:876\u2013881","journal-title":"Pediatr Radiol"},{"key":"4068_CR88","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1080\/00365520801971744","volume":"43","author":"CP Li","year":"2008","unstructured":"Li CP, Chao Y, Chen LT et al (2008) Fever after transcatheter arterial chemoembolization for hepatocellular carcinoma: incidence and risk factor analysis. Scand J Gastroenterol 43:992\u2013999","journal-title":"Scand J Gastroenterol"},{"key":"4068_CR89","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1053\/ajkd.2002.32770","volume":"39","author":"JJ Bissler","year":"2002","unstructured":"Bissler JJ, Racadio J, Donnelly LF et al (2002) Reduction of postembolization syndrome after ablation of renal angiomyolipoma. Am J Kidney Dis 39:966\u2013971","journal-title":"Am J Kidney Dis"},{"key":"4068_CR90","unstructured":"(2015) SIOPEL website. www.siopel.org . Accessed 12 Dec 2017"}],"container-title":["Pediatric Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00247-018-4068-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-018-4068-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-018-4068-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T17:56:02Z","timestamp":1719770162000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00247-018-4068-1"}},"subtitle":["Part 1: Endovascular interventions"],"short-title":[],"issued":{"date-parts":[[2018,1,23]]},"references-count":90,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["4068"],"URL":"https:\/\/doi.org\/10.1007\/s00247-018-4068-1","relation":{},"ISSN":["0301-0449","1432-1998"],"issn-type":[{"value":"0301-0449","type":"print"},{"value":"1432-1998","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,23]]}}}