{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T21:15:02Z","timestamp":1789766102479,"version":"4.0.1"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T00:00:00Z","timestamp":1619481600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T00:00:00Z","timestamp":1619481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Radiol"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s00247-021-05065-0","type":"journal-article","created":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T03:18:25Z","timestamp":1619493505000},"page":"1608-1620","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Imaging findings of multisystem inflammatory syndrome in children associated with COVID-19"],"prefix":"10.1007","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3540-6580","authenticated-orcid":false,"given":"Pablo","family":"Caro-Dom\u00ednguez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Navallas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Riaza-Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Ghadimi Mahani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos F.","family":"Ugas Charcape","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Israel","family":"Valverde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felice","family":"D\u2019Arco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seema","family":"Toso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan Cheng","family":"Shelmerdine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joost","family":"van Schuppen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurelio","family":"Secinaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Gr\u00e4fe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisol","family":"Camacho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olaf","family":"Neth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Woo","family":"Goo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian J.","family":"Kellenberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,27]]},"reference":[{"key":"5065_CR1","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1056\/NEJMe2023158","volume":"383","author":"M Levin","year":"2020","unstructured":"Levin M (2020) Childhood multisystem inflammatory syndrome \u2014 a new challenge in the pandemic. N Engl J Med 383:393\u2013395","journal-title":"N Engl J Med"},{"key":"5065_CR2","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1542\/hpeds.2020-0123","volume":"10","author":"VG Jones","year":"2020","unstructured":"Jones VG, Mills M, Suarez D et al (2020) COVID-19 and Kawasaki disease: novel virus and novel case. Hosp Pediatr 10:537\u2013540","journal-title":"Hosp Pediatr"},{"key":"5065_CR3","volume-title":"NHS warning","author":"Pediatric Critical Care Society","year":"2020","unstructured":"Pediatric Critical Care Society (2020) NHS warning. Retweet. https:\/\/twitter.com\/PICSociety\/status\/1254508725227982848"},{"key":"5065_CR4","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1016\/S0140-6736(20)31094-1","volume":"395","author":"S Riphagen","year":"2020","unstructured":"Riphagen S, Gomez X, Gonzalez-Martinez C et al (2020) Hyperinflammatory shock in children during COVID-19 pandemic. Lancet 395:1607\u20131608","journal-title":"Lancet"},{"key":"5065_CR5","doi-asserted-by":"publisher","first-page":"m2094","DOI":"10.1136\/bmj.m2094","volume":"369","author":"J Toubiana","year":"2020","unstructured":"Toubiana J, Poirault C, Corsia A et al (2020) Kawasaki-like multisystem inflammatory syndrome in children during the COVID-19 pandemic in Paris, France: prospective observational study. BMJ 369:m2094","journal-title":"BMJ"},{"key":"5065_CR6","doi-asserted-by":"publisher","first-page":"1771","DOI":"10.1016\/S0140-6736(20)31103-X","volume":"395","author":"L Verdoni","year":"2020","unstructured":"Verdoni L, Mazza A, Gervasoni A et al (2020) An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet 395:1771\u20131778","journal-title":"Lancet"},{"key":"5065_CR7","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1001\/jama.2020.10369","volume":"324","author":"E Whittaker","year":"2020","unstructured":"Whittaker E, Bamford A, Kenny J et al (2020) Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2. JAMA 324:259\u2013269","journal-title":"JAMA"},{"key":"5065_CR8","volume-title":"Paediatric multisystem inflammatory syndrome temporally associated with COVID-19 (PJIMS) \u2014 guidance for clinicians","author":"Royal College of Paediatric and Child Health","year":"2020","unstructured":"Royal College of Paediatric and Child Health (2020) Paediatric multisystem inflammatory syndrome temporally associated with COVID-19 (PJIMS) \u2014 guidance for clinicians. RCPCH website. https:\/\/www.rcpch.ac.uk\/resources\/guidance-paediatric-multisystem-inflammatory-syndrome-temporally-associated-covid-19. Accessed 12 Feb 2021"},{"key":"5065_CR9","volume-title":"Multisystem inflammatory syndrome in children and adolescents with COVID-19. Scientific brief","author":"World Health Organization","year":"2020","unstructured":"World Health Organization (2020) Multisystem inflammatory syndrome in children and adolescents with COVID-19. Scientific brief. WHO website. https:\/\/www.who.int\/publications\/i\/item\/multisystem-inflammatory-syndrome-in-children-and-adolescents-with-covid-19. Accessed 12 Feb 2021"},{"key":"5065_CR10","volume-title":"Multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 (COVID-19)","author":"Centers for Disease Control and Prevention","year":"2020","unstructured":"Centers for Disease Control and Prevention (2020) Multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 (COVID-19). CDC website. https:\/\/emergency.cdc.gov\/han\/2020\/han00432.asp. Accessed 12 Feb 2021"},{"key":"5065_CR11","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1056\/NEJMoa2021756","volume":"383","author":"EM Dufort","year":"2020","unstructured":"Dufort EM, Koumans EH, Chow et al (2020) Multisystem inflammatory syndrome in children in New York State. N Engl J Med 383:347\u2013358","journal-title":"N Engl J Med"},{"key":"5065_CR12","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1056\/NEJMoa2021680","volume":"383","author":"LR Feldstein","year":"2020","unstructured":"Feldstein LR, Rose EB, Horwitz et al (2020) Multisystem inflammatory syndrome in U.S. children and adolescents. N Engl J Med 383:334\u2013346","journal-title":"N Engl J Med"},{"key":"5065_CR13","doi-asserted-by":"publisher","first-page":"E1","DOI":"10.1148\/radiol.2020202543","volume":"298","author":"S Hameed","year":"2020","unstructured":"Hameed S, Elbaaly H, Reid CEL et al (2020) Spectrum of imaging findings on chest radiographs, US, CT, and MRI images in multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19. Radiology 298:E1\u2013E10","journal-title":"Radiology"},{"key":"5065_CR14","doi-asserted-by":"crossref","unstructured":"Blondiaux E, Parisot P, Redheuil A et al (2020) Cardiac MRI of children with multisystem inflammatory syndrome associated with COVID-19. Radiology 297:E283\u2013E288","DOI":"10.1148\/radiol.2020202288"},{"key":"5065_CR15","doi-asserted-by":"crossref","unstructured":"Blumfield E, Levin TL, Kurian J et al (2021) Imaging findings in multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease (COVID-19). AJR Am J Roentgenol 216:507\u2013517","DOI":"10.2214\/AJR.20.24032"},{"key":"5065_CR16","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1002\/ppul.10333","volume":"36","author":"AF Freeman","year":"2003","unstructured":"Freeman AF, Crawford SE, Finn LS et al (2003) Inflammatory pulmonary nodules in Kawasaki disease. Pediatr Pulmonol 36:103\u2013106","journal-title":"Pediatr Pulmonol"},{"key":"5065_CR17","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1007\/BF02010633","volume":"20","author":"T Umezawa","year":"1989","unstructured":"Umezawa T, Saji T, Matsuo N, Odagiri K (1989) Chest X-ray findings in the acute phase of Kawasaki disease. Pediatr Radiol 20:48\u201351","journal-title":"Pediatr Radiol"},{"key":"5065_CR18","doi-asserted-by":"publisher","unstructured":"Cheng C, Li C, Zhao T et al (2020) COVID-19 with rheumatic diseases: a report of 5 cases. Clin Rheumatol. https:\/\/doi.org\/10.1007\/s10067-020-05160-x","DOI":"10.1007\/s10067-020-05160-x"},{"key":"5065_CR19","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1001\/jama.2020.10374","volume":"324","author":"EW Cheung","year":"2020","unstructured":"Cheung EW, Zachariah P, Gorelik M et al (2020) Multisystem inflammatory syndrome related to COVID-19 in previously healthy children and adolescents in New York City. JAMA 324:294\u2013926","journal-title":"JAMA"},{"key":"5065_CR20","doi-asserted-by":"publisher","first-page":"2880","DOI":"10.1002\/jmv.26206","volume":"92","author":"KF Ng","year":"2020","unstructured":"Ng KF, Kothari Y, Bandi S et al (2020) COVID-19 multisystem inflammatory syndrome in three teenagers with confirmed SARS-CoV-2 infection. J Med Virol 92:2880\u20132886","journal-title":"J Med Virol"},{"key":"5065_CR21","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.jpeds.2020.06.045","volume":"224","author":"S Kaushik","year":"2020","unstructured":"Kaushik S, Aydin SI, Derespina KR et al (2020) Multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2 infection: a multi-institutional study from New York City. J Pediatr 224:24\u201329","journal-title":"J Pediatr"},{"key":"5065_CR22","doi-asserted-by":"publisher","first-page":"1346","DOI":"10.1017\/S1047951120001857","volume":"30","author":"M Rodriguez-Gonzalez","year":"2020","unstructured":"Rodriguez-Gonzalez M, Rodriguez-Campoy P, Sanchez-Codez M et al (2020) New onset severe right ventricular failure associated with COVID-19 in a young infant without previous heart disease. Cardiol Young 30:1346\u20131349","journal-title":"Cardiol Young"},{"key":"5065_CR23","doi-asserted-by":"publisher","first-page":"E376","DOI":"10.1016\/S2665-9913(20)30137-5","volume":"2","author":"CE Pain","year":"2020","unstructured":"Pain CE, Felsenstein S, Cleary G et al (2020) Novel paediatric presentation of COVID-19 with ARDS and cytokine storm syndrome without respiratory symptoms. Lancet Rheumatol 2:E376\u2013E379","journal-title":"Lancet Rheumatol"},{"key":"5065_CR24","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1136\/annrheumdis-2020-217960","volume":"79","author":"M Pouletty","year":"2020","unstructured":"Pouletty M, Borocco ON et al (2020) Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort. Ann Rheum Dis 79:999\u20131006","journal-title":"Ann Rheum Dis"},{"key":"5065_CR25","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.1007\/s00246-020-02391-2","volume":"41","author":"T Ramcharan","year":"2020","unstructured":"Ramcharan T, Nolan O, Lai CY et al (2020) Paediatric inflammatory multisystem syndrome: temporally associated with SARS-CoV-2 (PIMS-TS): cardiac features, management and short-term outcomes at a UK tertiary paediatric hospital. Pediatr Cardiol 41:1391\u20131401","journal-title":"Pediatr Cardiol"},{"key":"5065_CR26","doi-asserted-by":"publisher","first-page":"100527","DOI":"10.1016\/j.eclinm.2020.100527","volume":"26","author":"M Ahmed","year":"2020","unstructured":"Ahmed M, Advani S, Moreira A et al (2020) Multisystem inflammatory syndrome in children: a systematic review. EClinicalMedicine 26:100527","journal-title":"EClinicalMedicine"},{"key":"5065_CR27","doi-asserted-by":"publisher","unstructured":"Theocharis P, Wong J, Pushparajah K et al (2020) Multimodality cardiac evaluation in children and young adults with multisystem inflammation associated with COVID-19. Eur Heart J Cardiovasc Imaging. https:\/\/doi.org\/10.1093\/ehjci\/jeaa212","DOI":"10.1093\/ehjci\/jeaa212"},{"key":"5065_CR28","doi-asserted-by":"publisher","first-page":"1859","DOI":"10.1093\/eurheartj\/ehaa288","volume":"41","author":"IC Kim","year":"2020","unstructured":"Kim IC, Kim JY, Ha K, Han S (2020) COVID-19-related myocarditis in a 21-year-old female patient. Eur Heart J 41:1859","journal-title":"Eur Heart J"},{"key":"5065_CR29","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1001\/jamacardio.2020.1096","volume":"5","author":"RM Inciardi","year":"2020","unstructured":"Inciardi RM, Lupi L, Zaccone G et al (2020) Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19). JAMA Cardiol 5:819\u2013824","journal-title":"JAMA Cardiol"},{"key":"5065_CR30","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1161\/CIRCULATIONAHA.120.048360","volume":"142","author":"Z Belhadjer","year":"2020","unstructured":"Belhadjer Z, M\u00e9ot M, Bajolle F et al (2020) Acute heart failure in multisystem inflammatory syndrome in children (MIS-C) in the context of global SARS-CoV-2 pandemic. Circulation 142:429\u2013436","journal-title":"Circulation"},{"key":"5065_CR31","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1007\/s11886-020-01292-3","volume":"22","author":"H Zhu","year":"2020","unstructured":"Zhu H, Rhee J-W, Cheng P et al (2020) Cardiovascular complications in patients with COVID-19: consequences of viral toxicities and host immune response. Curr Cardiol Rep 22:32","journal-title":"Curr Cardiol Rep"},{"key":"5065_CR32","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/s13613-020-00690-8","volume":"10","author":"M Grimaud","year":"2020","unstructured":"Grimaud M, Starck J, Levy M et al (2020) Acute myocarditis and multisystem inflammatory emerging disease following SARS-CoV-2 infection in critically ill children. Ann Intensive Care 10:69","journal-title":"Ann Intensive Care"},{"key":"5065_CR33","doi-asserted-by":"publisher","first-page":"e19","DOI":"10.1016\/S2352-4642(20)30165-6","volume":"4","author":"L Tullie","year":"2020","unstructured":"Tullie L, Ford K, Bisharat M et al (2020) Gastrointestinal features in children with COVID-19: an observation of varied presentation in eight children. Lancet Child Adores Health 4:e19\u2013e20","journal-title":"Lancet Child Adores Health"},{"key":"5065_CR34","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1007\/BF02012457","volume":"23","author":"CJ Sivit","year":"1993","unstructured":"Sivit CJ, Newman KD, Chandra RS (1993) Visualization of enlarged mesenteric lymph nodes at US examination. Pediatr Radiol 23:471\u2013475","journal-title":"Pediatr Radiol"},{"key":"5065_CR35","doi-asserted-by":"publisher","first-page":"E207","DOI":"10.1148\/radiol.2020201908","volume":"297","author":"R Bhayana","year":"2020","unstructured":"Bhayana R, Som A, Li MD et al (2020) Abdominal imaging findings in COVID-19: preliminary observations. Radiology 297:E207\u2013E215","journal-title":"Radiology"},{"key":"5065_CR36","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1007\/s11239-020-02138-z","volume":"50","author":"GD Barnes","year":"2020","unstructured":"Barnes GD, Burnett A, Allen A et al (2020) Thromboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the anticoagulation forum. J Thromb Thrombolysis 50:72\u201381","journal-title":"J Thromb Thrombolysis"},{"key":"5065_CR37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1001\/jamaneurol.2020.2687","volume":"77","author":"O Abdel-Mannan","year":"2020","unstructured":"Abdel-Mannan O, Eyre M, L\u00f6bel U et al (2020) Neurologic and radiographic findings associated with COVID-19 infection in children. JAMA Neurol 77:1\u20136","journal-title":"JAMA Neurol"},{"key":"5065_CR38","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1148\/rg.2017160085","volume":"37","author":"J Starkey","year":"2017","unstructured":"Starkey J, Kobayashi N, Numaguchi Y, Moritani T (2017) Cytotoxic lesions of the corpus callosum that show restricted diffusion: mechanisms, causes, and manifestations. Radiographics 37:562\u2013576","journal-title":"Radiographics"},{"key":"5065_CR39","doi-asserted-by":"publisher","first-page":"E239","DOI":"10.1148\/radiol.2020202466","volume":"297","author":"Y Purcell","year":"2020","unstructured":"Purcell Y, Lecler A, Saragoussi E et al (2020) Neurologic involvement of patients with coronavirus disease 2019: making the most of MRI. Radiology 297:E239","journal-title":"Radiology"}],"container-title":["Pediatric Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-021-05065-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00247-021-05065-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-021-05065-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,25]],"date-time":"2022-12-25T09:31:10Z","timestamp":1671960670000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00247-021-05065-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,27]]},"references-count":39,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["5065"],"URL":"https:\/\/doi.org\/10.1007\/s00247-021-05065-0","relation":{},"ISSN":["0301-0449","1432-1998"],"issn-type":[{"value":"0301-0449","type":"print"},{"value":"1432-1998","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,27]]},"assertion":[{"value":"31 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 November 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 April 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}