{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:26:14Z","timestamp":1740108374827,"version":"3.37.3"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T00:00:00Z","timestamp":1713312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T00:00:00Z","timestamp":1713312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Radiol"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome is a recently described entity that refers to a specific pattern of cerebellar edema with restricted diffusion and crowding of the fourth ventricle among other findings. The syndrome is commonly associated with toxic opioid exposure. While most commonly seen in adults, we present a case of a 2-year-old girl who survived characteristic history and imaging findings of CHANTER syndrome.<\/jats:p>","DOI":"10.1007\/s00247-024-05928-2","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T08:51:22Z","timestamp":1713343882000},"page":"1220-1223","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Case of pediatric cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome in a 2-year-old girl"],"prefix":"10.1007","volume":"54","author":[{"given":"Robert A.","family":"Koenigsberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0884-8362","authenticated-orcid":false,"given":"Luke","family":"Ross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Timmerman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rithika","family":"Surineni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kara","family":"Breznak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tina C.","family":"Loven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,17]]},"reference":[{"key":"5928_CR1","doi-asserted-by":"publisher","first-page":"3496","DOI":"10.1016\/j.radcr.2023.07.015","volume":"18","author":"MF Atac","year":"2023","unstructured":"Atac MF, Vilanilam GK, Damalcheruvu PR et al (2023) Cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome in the setting of opioid and phencyclidine use. Radiol Case Rep 18:3496\u20133500. https:\/\/doi.org\/10.1016\/j.radcr.2023.07.015","journal-title":"Radiol Case Rep"},{"key":"5928_CR2","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1007\/s12028-018-00666-4","volume":"31","author":"AS Jasne","year":"2019","unstructured":"Jasne AS, Alsherbini KH, Smith MS et al (2019) Cerebellar hippocampal and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome. Neurocrit Care 31:288\u2013296. https:\/\/doi.org\/10.1007\/s12028-018-00666-4","journal-title":"Neurocrit Care"},{"key":"5928_CR3","unstructured":"(2023) Opioid overdose. https:\/\/www.cdc.gov\/drugoverdose\/deaths\/opioid-overdose.html. Accessed 26 Feb 2024"},{"key":"5928_CR4","doi-asserted-by":"publisher","first-page":"e186558","DOI":"10.1001\/jamanetworkopen.2018.6558","volume":"1","author":"JR Gaither","year":"2018","unstructured":"Gaither JR, Shabanova V, Leventhal JM (2018) US national trends in pediatric deaths from prescription and illicit opioids, 1999\u20132016. JAMA Netw Open 1:e186558. https:\/\/doi.org\/10.1001\/jamanetworkopen.2018.6558","journal-title":"JAMA Netw Open"},{"key":"5928_CR5","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1212\/WNL.0000000000009293","volume":"94","author":"DD Kim","year":"2020","unstructured":"Kim DD, Prasad AN (2020) Clinical and radiologic features of pediatric opioid use-associated neurotoxicity with cerebellar edema (POUNCE) syndrome. Neurology 94:710\u2013712. https:\/\/doi.org\/10.1212\/WNL.0000000000009293","journal-title":"Neurology"},{"key":"5928_CR6","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1177\/1971400920903106","volume":"33","author":"AS Jasne","year":"2020","unstructured":"Jasne AS, Alsherbini KA, Smith MS et al (2020) Response to \u201cMalignant cerebella edema in three-year-old girl following accidental opioid ingestion and fentanyl administration.\u201d Neuroradiol J 33:158. https:\/\/doi.org\/10.1177\/1971400920903106","journal-title":"Neuroradiol J"},{"key":"5928_CR7","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1177\/1971400917691994","volume":"30","author":"S Shrot","year":"2017","unstructured":"Shrot S, Poretti A, Tucker EW et al (2017) Acute brain injury following illicit drug abuse in adolescent and young adult patients: spectrum of neuroimaging findings. Neuroradiol J 30:144\u2013115. https:\/\/doi.org\/10.1177\/1971400917691994","journal-title":"Neuroradiol J"},{"key":"5928_CR8","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/0006-8993(90)91635-t","volume":"523","author":"IS Zagon","year":"1990","unstructured":"Zagon IS, Gibo DM, McLaughlin PJ (1990) Adult and developing human cerebella exhibit different profiles of opioid binding sites. Brain Res 523:62\u201368. https:\/\/doi.org\/10.1016\/0006-8993(90)91635-t","journal-title":"Brain Res"},{"key":"5928_CR9","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1016\/j.jpeds.2013.06.058","volume":"163","author":"EJ Lavonas","year":"2013","unstructured":"Lavonas EJ, Banner W, Bradt P et al (2013) Root causes, clinical effects, and outcomes of unintentional exposures to buprenorphine by young children. J Pediatr 163:1377\u20131383. https:\/\/doi.org\/10.1016\/j.jpeds.2013.06.058. e1\u20133","journal-title":"J Pediatr"},{"key":"5928_CR10","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1056\/NEJMra1202561","volume":"367","author":"EW Boyer","year":"2012","unstructured":"Boyer EW (2012) Management of opioid analgesic overdose. N Engl J Med 367:146\u2013155. https:\/\/doi.org\/10.1056\/NEJMra1202561","journal-title":"N Engl J Med"},{"key":"5928_CR11","first-page":"476","volume":"113","author":"WV Stoecker","year":"2016","unstructured":"Stoecker WV, Madsen DE, Cole JG, Woolsey Z (2016) Boys at risk: fatal accidental fentanyl ingestions in children: analysis of cases reported to the FDA 2004\u20132013. Mo Med 113:476\u2013479","journal-title":"Mo Med"},{"key":"5928_CR12","doi-asserted-by":"publisher","first-page":"1136","DOI":"10.3174\/ajnr.A7569","volume":"43","author":"KS Mallikarjun","year":"2022","unstructured":"Mallikarjun KS, Parsons MS, Nigogosyan Z et al (2022) Neuroimaging findings in CHANTER syndrome: a case series. AJNR Am J Neuroradiol 43:1136\u20131141. https:\/\/doi.org\/10.3174\/ajnr.A7569","journal-title":"AJNR Am J Neuroradiol"}],"container-title":["Pediatric Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-024-05928-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00247-024-05928-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-024-05928-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T03:48:55Z","timestamp":1718682535000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00247-024-05928-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,17]]},"references-count":12,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2024,6]]}},"alternative-id":["5928"],"URL":"https:\/\/doi.org\/10.1007\/s00247-024-05928-2","relation":{},"ISSN":["1432-1998"],"issn-type":[{"type":"electronic","value":"1432-1998"}],"subject":[],"published":{"date-parts":[[2024,4,17]]},"assertion":[{"value":"2 October 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 April 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 April 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}