{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T19:07:54Z","timestamp":1780772874118,"version":"3.54.1"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"National Hospital"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Radiol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Restrictive cerebral venopathy<\/jats:italic>\n                    was recently described in a young patient with cerebral venous ischemia, elevated intracranial pressure, and intracranial calcifications. It was anatomically characterized by extensive formation of tortuous small to medium-sized cortical veins and angiographic absence of the deep venous system. We report similar, albeit not identical, angiographic features in an 11-year-old girl with infantile autism, attention deficit disorder, dyslexia, and camptodactyly. Angiography revealed a venous anomaly characterized by diffuse marked tortuousities involving mainly pial and small cortical veins, partial maldevelopment of the deep venous system, and aplasia of the transverse sinuses. Magnetic resonance imaging showed no signs of venous ischemia. Genetic analyses identified a complex rearrangement involving three chromosomal segments. In conclusion, a unique case of non-restrictive cerebral venous dysgenesis associated with chromotripsis is presented.\n                  <\/jats:p>","DOI":"10.1007\/s00247-026-06566-6","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T13:18:23Z","timestamp":1773407903000},"page":"1189-1195","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Non-restrictive cerebral venous dysgenesis in an 11-year-old girl: a case report"],"prefix":"10.1007","volume":"56","author":[{"given":"Maryam","family":"Mozaffari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasmus Holmboe","family":"Dahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malene Landbo","family":"B\u00f8rresen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina Duelund","family":"Hjortsh\u00f8j","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goetz","family":"Benndorf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"6566_CR1","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1177\/159101991301900110","volume":"19","author":"JMN Enslin","year":"2013","unstructured":"Enslin JMN, Lefeuvre D, Taylor A (2013) Developmental venous anomaly with contralateral impaired venous drainage in a 17-year-old male. A case report. Interv Neuroradiol 19:67\u201372.\u00a0https:\/\/doi.org\/10.1177\/159101991301900110br","journal-title":"Interv Neuroradiol"},{"key":"6566_CR2","first-page":"1031","volume":"20","author":"R Willinsky","year":"1999","unstructured":"Willinsky R, Goyal M, terBrugge K, Montanera W (1999) Tortuous, engorged pial veins in intracranial dural arteriovenous fistulas: correlations with presentation, location, and MR findings in 122 patients. AJNR Am J Neuroradiol\u00a020:1031\u20136br.","journal-title":"AJNR Am J Neuroradiol"},{"key":"6566_CR3","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1177\/1591019918821861","volume":"25","author":"ZA Voronovich","year":"2019","unstructured":"Voronovich ZA, Wolfe K, Foster K et al (2019) Restrictive cerebral cortical venopathy: a new clinicopathological entity. Interv Neuroradiol 25:322\u2013329.\u00a0https:\/\/doi.org\/10.1177\/1591019918821861br","journal-title":"Interv Neuroradiol"},{"key":"6566_CR4","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1016\/j.nec.2010.03.011","volume":"21","author":"C Raybaud","year":"2010","unstructured":"Raybaud C (2010) Normal and abnormal embryology and development of the intracranial vascular system. Neurosurg Clin N Am 21:399\u2013426.\u00a0https:\/\/doi.org\/10.1016\/j.nec.2010.03.011br","journal-title":"Neurosurg Clin N Am"},{"key":"6566_CR5","doi-asserted-by":"publisher","unstructured":"Das D, Tanaka M, Roy BK, Singh V (2013) Hemispheric venous dysgenesis in a woman presenting with seizures, weakness and parkinsonism. BMJ Case Rep 2013. https:\/\/doi.org\/10.1136\/bcr-2013-009413br","DOI":"10.1136\/bcr-2013-009413br"},{"key":"6566_CR6","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1007\/s002340050010","volume":"42","author":"CJ Chen","year":"2000","unstructured":"Chen CJ (2000) Unilateral congenital cerebral venous dysgenesis. Neuroradiology 42:40\u201342.\u00a0https:\/\/doi.org\/10.1007\/s002340050010br","journal-title":"Neuroradiology"},{"key":"6566_CR7","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1007\/BF00304794","volume":"8","author":"I Kato","year":"1992","unstructured":"Kato I, Shirane R, Ogawa A, Yoshimoto T (1992) Congenital cerebral venous dysgenesis. Decreased cerebral blood flow in deep cerebral regions revealed by SPECT. Childs Nerv Syst 8:422\u20135.\u00a0https:\/\/doi.org\/10.1007\/BF00304794br","journal-title":"Childs Nerv Syst"},{"key":"6566_CR8","doi-asserted-by":"publisher","first-page":"393","DOI":"10.3389\/fgene.2019.00393","volume":"10","author":"AS Koltsova","year":"2019","unstructured":"Koltsova AS, Pendina AA, Efimova OA, et al (2019) On the complexity of mechanisms and consequences of chromothripsis: an update. Front Genet 10:393.\u00a0https:\/\/doi.org\/10.3389\/fgene.2019.00393","journal-title":"Front Genet"}],"container-title":["Pediatric Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-026-06566-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00247-026-06566-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-026-06566-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:02:23Z","timestamp":1777658543000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00247-026-06566-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,13]]},"references-count":8,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,5]]}},"alternative-id":["6566"],"URL":"https:\/\/doi.org\/10.1007\/s00247-026-06566-6","relation":{},"ISSN":["1432-1998"],"issn-type":[{"value":"1432-1998","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,13]]},"assertion":[{"value":"2 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 February 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 February 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 March 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"G.B. received research support from and holds patents with Siemens Healthineers. M.L.B., M.M., R.H.D., and T.D.H. have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}