{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T11:03:47Z","timestamp":1789470227923,"version":"build-2803163510"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Radiol"],"DOI":"10.1007\/s00247-026-06679-y","type":"journal-article","created":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T10:07:05Z","timestamp":1780567625000},"page":"2292-2310","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Radiation dose and objective image quality of photon-counting detector computed tomography in pediatric imaging: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"56","author":[{"given":"Ceren","family":"Altintas Mese","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail","family":"Mese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,4]]},"reference":[{"key":"6679_CR1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-025-04235-3","volume":"23","author":"S Han","year":"2025","unstructured":"Han S, Soh J, Nah S et al (2025) Pediatric computed tomography scan and subsequent risk of malignancy: a nationwide population-based cohort study in Korea using National Cancer Institute dosimetry system for computed tomography (NCICT). BMC Med 23:355","journal-title":"BMC Med"},{"key":"6679_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00247-023-05823-2","volume":"54","author":"I Mese","year":"2024","unstructured":"Mese I, Altintas Mese C, Demirsoy U, Anik Y (2024) Innovative advances in pediatric radiology: computed tomography reconstruction techniques, photon-counting detector computed tomography, and beyond. Pediatr Radiol 54:1\u201311","journal-title":"Pediatr Radiol"},{"key":"6679_CR3","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1007\/s00247-022-05526-0","volume":"53","author":"E Nagy","year":"2023","unstructured":"Nagy E, Tschauner S, Schramek C, Sorantin E (2023) Paediatric CT made easy. Pediatr Radiol 53:581\u2013588","journal-title":"Pediatr Radiol"},{"key":"6679_CR4","doi-asserted-by":"publisher","first-page":"1726","DOI":"10.1007\/s00247-023-05684-9","volume":"53","author":"I Mese","year":"2023","unstructured":"Mese I (2023) The potential for photon-counting computed tomography and deep learning to reduce radiation dose in paediatric radiology: reply to Nagy et al. Pediatr Radiol 53:1726\u20131727","journal-title":"Pediatr Radiol"},{"key":"6679_CR5","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.230803","volume":"309","author":"CH McCollough","year":"2023","unstructured":"McCollough CH, Rajiah PS (2023) Milestones in CT: past, present, and future. Radiology 309:e230803","journal-title":"Radiology"},{"key":"6679_CR6","doi-asserted-by":"publisher","first-page":"1788","DOI":"10.1093\/bjr\/tqaf116","volume":"98","author":"L Ren","year":"2025","unstructured":"Ren L, Duan X, Ahn R et al (2025) Photon-counting detector CT: technology overview and radiation dose reduction. Br J Radiol 98:1788\u20131801","journal-title":"Br J Radiol"},{"key":"6679_CR7","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1007\/s11604-022-01350-6","volume":"41","author":"Y Nakamura","year":"2023","unstructured":"Nakamura Y, Higaki T, Kondo S et al (2023) An introduction to photon-counting detector CT (PCD CT) for radiologists. Jpn J Radiol 41:266\u2013282","journal-title":"Jpn J Radiol"},{"key":"6679_CR8","doi-asserted-by":"publisher","DOI":"10.1093\/radadv\/umae012","author":"MJ Siegel","year":"2024","unstructured":"Siegel MJ, Ramirez-Giraldo JC (2024) Photon counting detector computed tomography in pediatric cardiothoracic CT imaging. Radiol Adv. https:\/\/doi.org\/10.1093\/radadv\/umae012","journal-title":"Radiol Adv"},{"key":"6679_CR9","doi-asserted-by":"publisher","first-page":"1821","DOI":"10.1093\/bjr\/tqaf088","volume":"98","author":"KK Horst","year":"2025","unstructured":"Horst KK, Yu L, Larson HT, Siegel MJ (2025) Photon-counting detector CT in paediatric imaging: a review of current literature and future directions. Br J Radiol 98:1821\u20131833","journal-title":"Br J Radiol"},{"key":"6679_CR10","doi-asserted-by":"publisher","first-page":"580","DOI":"10.2214\/AJR.22.28391","volume":"220","author":"J Cao","year":"2023","unstructured":"Cao J, Bache S, Schwartz FR, Frush D (2023) Pediatric applications of photon-counting detector CT. Am J Roentgenol 220:580\u2013589","journal-title":"Am J Roentgenol"},{"key":"6679_CR11","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1007\/s00330-025-11719-6","volume":"36","author":"S Hellms","year":"2026","unstructured":"Hellms S, Werncke T, B\u00f6ttcher J et al (2026) Reduction of radiation exposure and preserved image quality using photon-counting detector cardiac computed tomography without electrocardiographic gating in children with congenital heart disease. Eur Radiol 36:324\u2013333","journal-title":"Eur Radiol"},{"key":"6679_CR12","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1097\/RLI.0000000000001234","volume":"61","author":"MB Krueger","year":"2026","unstructured":"Krueger MB, Werncke T, Eicke M et al (2026) Photon-counting detector CT enables pediatric low-dose chest imaging with further reduction of radiation exposure. Invest Radiol 61:318\u2013325","journal-title":"Invest Radiol"},{"key":"6679_CR13","doi-asserted-by":"publisher","first-page":"1202","DOI":"10.1007\/s00247-025-06209-2","volume":"55","author":"FR Schwartz","year":"2025","unstructured":"Schwartz FR, Bache S, Lee R et al (2025) Photon-counting CT yields superior abdominopelvic image quality at lower radiation and iodinated contrast doses. Pediatr Radiol 55:1202\u20131211","journal-title":"Pediatr Radiol"},{"key":"6679_CR14","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.223088","volume":"307","author":"T Dirrichs","year":"2023","unstructured":"Dirrichs T, Tietz E, R\u00fcffer A et al (2023) Photon-counting versus dual-source CT of congenital heart defects in neonates and infants: initial experience. Radiology 307:e223088","journal-title":"Radiology"},{"key":"6679_CR15","doi-asserted-by":"publisher","first-page":"363","DOI":"10.2214\/AJR.23.29077","volume":"221","author":"MJ Siegel","year":"2023","unstructured":"Siegel MJ, Bugenhagen SM, Sanchez A et al (2023) Comparison of radiation dose and image quality of pediatric high-resolution chest CT between photon-counting detector CT and energy-integrated detector CT: a matched study. Am J Roentgenol 221:363\u2013371","journal-title":"Am J Roentgenol"},{"key":"6679_CR16","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1097\/RCT.0000000000001730","volume":"50","author":"MJ Siegel","year":"2026","unstructured":"Siegel MJ, Thomas MA, Haq A et al (2026) Comparison of radiation dose and image quality in pediatric abdominopelvic photon-counting versus energy-integrating detector CT. J Comput Assist Tomogr 50:73\u201380","journal-title":"J Comput Assist Tomogr"},{"key":"6679_CR17","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.3174\/ajnr.A8276","volume":"45","author":"JS Lee","year":"2024","unstructured":"Lee JS, Kim J, Bapuraj JR, Srinivasan A (2024) Comparison of image quality and radiation dose in pediatric temporal bone CT using photon-counting detector CT and energy-integrating detector CT. AJNR Am J Neuroradiol 45:1322\u20131326","journal-title":"AJNR Am J Neuroradiol"},{"key":"6679_CR18","doi-asserted-by":"publisher","first-page":"1690","DOI":"10.1007\/s00247-025-06295-2","volume":"55","author":"K Naceanceno","year":"2025","unstructured":"Naceanceno K, Thomas A, Zhang Z et al (2025) Quantifying performance enhancements in photon-counting pediatric head CT: A direct comparison with energy-integrating CT. Pediatr Radiol 55:1690\u20131701","journal-title":"Pediatr Radiol"},{"key":"6679_CR19","doi-asserted-by":"publisher","first-page":"2779","DOI":"10.1007\/s00247-025-06394-0","volume":"55","author":"AA Daniels","year":"2025","unstructured":"Daniels AA, Pinkney LP, Strubel NA et al (2025) Pediatric photon-counting chest CT enables iodinated contrast dose reduction with preserved image quality. Pediatr Radiol 55:2779\u20132791","journal-title":"Pediatr Radiol"},{"key":"6679_CR20","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics16050735","volume":"16","author":"A Lollert","year":"2026","unstructured":"Lollert A, Souschek F, Abu-Tair T et al (2026) Photon-counting CT enables higher image quality at a lower radiation dose compared with a 256-slice energy-integrating detector CT in pediatric patients with congenital heart disease. Diagnostics 16:735","journal-title":"Diagnostics"},{"key":"6679_CR21","doi-asserted-by":"publisher","first-page":"2579","DOI":"10.1007\/s00247-025-06336-w","volume":"55","author":"GM Arguello Fletes","year":"2025","unstructured":"Arguello Fletes GM, Zhou W, Malone LJ et al (2025) Comparative radiation dose analysis in pediatric high-pitch cardiac CTA using photon-counting versus energy-integrating detector CT. Pediatr Radiol 55:2579\u20132589","journal-title":"Pediatr Radiol"},{"key":"6679_CR22","doi-asserted-by":"publisher","first-page":"1984","DOI":"10.1007\/s00247-024-06078-1","volume":"54","author":"AM El-Ali","year":"2024","unstructured":"El-Ali AM, Strubel N, Pinkney L et al (2024) Pediatric contrast-enhanced chest CT on a photon-counting detector CT: radiation dose and image quality compared to energy-integrated detector CT. Pediatr Radiol 54:1984\u20131995","journal-title":"Pediatr Radiol"},{"key":"6679_CR23","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71","journal-title":"BMJ"},{"key":"6679_CR24","unstructured":"Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors) (2024) Cochrane Handbook for Systematic Reviews of Interventions version 6.5 (updated August 2024). Cochrane. Available from www.training.cochrane.org\/handbook."},{"key":"6679_CR25","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-14-135","volume":"14","author":"X Wan","year":"2014","unstructured":"Wan X, Wang W, Liu J, Tong T (2014) Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range. BMC Med Res Methodol 14:135","journal-title":"BMC Med Res Methodol"},{"key":"6679_CR26","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1007\/s10654-010-9491-z","volume":"25","author":"A Stang","year":"2010","unstructured":"Stang A (2010) Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol 25:603\u2013605","journal-title":"Eur J Epidemiol"},{"key":"6679_CR27","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1007\/s00247-025-06467-0","volume":"56","author":"NH Dang","year":"2026","unstructured":"Dang NH, Zhou W, Arguello Fletes GM et al (2026) Balancing radiation dose and image quality in infants on photon-counting CT for pediatric cardiac imaging: comparing 70 kV and 120 kV protocols. Pediatr Radiol 56:545\u2013553","journal-title":"Pediatr Radiol"},{"key":"6679_CR28","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1007\/s00247-024-05939-z","volume":"54","author":"F St\u00e5lhammar","year":"2024","unstructured":"St\u00e5lhammar F, Aurumskj\u00f6ld M-L, Meyer S et al (2024) Photon-counting computed tomography for paediatric congenital heart defects yields images of high diagnostic quality with low radiation doses at both 70 kV and 90 kV. Pediatr Radiol 54:1187\u20131196","journal-title":"Pediatr Radiol"},{"key":"6679_CR29","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1007\/s00247-022-05574-6","volume":"53","author":"KK Horst","year":"2023","unstructured":"Horst KK, Hull NC, Thacker PG et al (2023) Pilot study to determine whether reduced-dose photon-counting detector chest computed tomography can reliably display Brody II score imaging findings for children with cystic fibrosis at radiation doses that approximate radiographs. Pediatr Radiol 53:1049\u20131056","journal-title":"Pediatr Radiol"},{"key":"6679_CR30","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1007\/s00247-022-05584-4","volume":"53","author":"I Tsiflikas","year":"2023","unstructured":"Tsiflikas I, Thater G, Ayx I et al (2023) Low dose pediatric chest computed tomography on a photon counting detector system - initial clinical experience. Pediatr Radiol 53:1057\u20131062","journal-title":"Pediatr Radiol"},{"key":"6679_CR31","doi-asserted-by":"crossref","unstructured":"Habib Geryes B, Moalla S, De Saint Etienne E, et al (2025) Photon-counting CT in pediatric patients: A multi-institutional evaluation of protocols and radiation exposure in 4,772 patients. Diagn Interv Imaging\u00a0107:186-197","DOI":"10.1016\/j.diii.2025.11.010"},{"key":"6679_CR32","doi-asserted-by":"publisher","DOI":"10.1002\/mp.17918","volume":"52","author":"DP Clark","year":"2025","unstructured":"Clark DP, Cao JY, Badea CT (2025) Denoising pediatric cardiac photon-counting CT data with sparse coding and data-adaptive, self-supervised deep learning. Med Phys 52:e17918","journal-title":"Med Phys"}],"container-title":["Pediatric Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-026-06679-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00247-026-06679-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00247-026-06679-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T10:17:27Z","timestamp":1789467447000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00247-026-06679-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,4]]},"references-count":32,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["6679"],"URL":"https:\/\/doi.org\/10.1007\/s00247-026-06679-y","relation":{},"ISSN":["1432-1998"],"issn-type":[{"value":"1432-1998","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,4]]},"assertion":[{"value":"11 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 May 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 June 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"None","order":1,"name":"Ethics","label":"Conflicts of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}