{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T03:36:20Z","timestamp":1791516980399,"version":"4.3.4"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2010,2,6]],"date-time":"2010-02-06T00:00:00Z","timestamp":1265414400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microb Ecol"],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1007\/s00248-010-9634-5","type":"journal-article","created":{"date-parts":[[2010,2,5]],"date-time":"2010-02-05T04:30:55Z","timestamp":1265344255000},"page":"479-486","source":"Crossref","is-referenced-by-count":84,"title":["Occurrence and Persistence of Erythromycin Resistance Genes (erm) and Tetracycline Resistance Genes (tet) in Waste Treatment Systems on Swine Farms"],"prefix":"10.1007","volume":"60","author":[{"given":"Jing","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Frederick C.","family":"Michel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinand","family":"Sreevatsan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Morrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongtang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,2,6]]},"reference":[{"key":"9634_CR1","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1017\/S1466252308001503","volume":"9","author":"FM Aarestrup","year":"2008","unstructured":"Aarestrup FM, Oliver Duran C, Burch DG (2008) Antimicrobial resistance in swine production. Anim Health Res Rev 9:135\u2013148","journal-title":"Anim Health Res Rev"},{"key":"9634_CR2","doi-asserted-by":"publisher","first-page":"2377","DOI":"10.1016\/j.watres.2008.01.005","volume":"42","author":"LT Angenent","year":"2008","unstructured":"Angenent LT, Mau M, George U, Zahn JA, Raskin L (2008) Effect of the presence of the antimicrobial tylosin in swine waste on anaerobic treatment. Water Res 42:2377\u20132384","journal-title":"Water Res"},{"key":"9634_CR3","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1093\/jac\/dkh333","volume":"54","author":"P Antunes","year":"2004","unstructured":"Antunes P, Machado J, Sousa JC, Peixe L (2004) Dissemination amongst humans and food products of animal origin of a Salmonella typhimurium clone expressing an integron-borne OXA-30 beta-lactamase. J Antimicrob Chemother 54:429\u2013434","journal-title":"J Antimicrob Chemother"},{"key":"9634_CR4","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.copbio.2008.05.006","volume":"19","author":"F Baquero","year":"2008","unstructured":"Baquero F, Martinez JL, Canton R (2008) Antibiotics and antibiotic resistance in water environments. Curr Opin Biotechnol 19:260\u2013265","journal-title":"Curr Opin Biotechnol"},{"key":"9634_CR5","doi-asserted-by":"publisher","first-page":"4785","DOI":"10.1128\/AEM.00252-07","volume":"73","author":"D Bibbal","year":"2007","unstructured":"Bibbal D, Dupouy V, Ferre JP, Toutain PL, Fayet O, Prere MF, Bousquet-Melou A (2007) Impact of three ampicillin dosage regimens on selection of ampicillin resistance in Enterobacteriaceae and excretion of bla\n                           TEM genes in swine feces. Appl Environ Microbiol 73:4785\u20134790","journal-title":"Appl Environ Microbiol"},{"key":"9634_CR6","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1111\/j.1574-6941.2008.00526.x","volume":"66","author":"CT Binh","year":"2008","unstructured":"Binh CT, Heuer H, Kaupenjohann M, Smalla K (2008) Piggery manure used for soil fertilization is a reservoir for transferable antibiotic resistance plasmids. FEMS Microbiol Ecol 66:25\u201337","journal-title":"FEMS Microbiol Ecol"},{"key":"9634_CR7","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1046\/j.1365-2672.2003.01988.x","volume":"95","author":"DP Blake","year":"2003","unstructured":"Blake DP, Hillman K, Fenlon DR, Low JC (2003) Transfer of antibiotic resistance between commensal and pathogenic members of the Enterobacteriaceae under ileal conditions. J Appl Microbiol 95:428\u2013436","journal-title":"J Appl Microbiol"},{"key":"9634_CR8","doi-asserted-by":"publisher","first-page":"2385","DOI":"10.2527\/jas.2007-0705","volume":"86","author":"J Chen","year":"2008","unstructured":"Chen J, Fluharty FL, St-Pierre N, Morrison M, Yu Z (2008) Technical note: occurrence in fecal microbiota of genes conferring resistance to both macrolide\u2013lincosamide\u2013streptogramin B and tetracyclines concomitant with feeding of beef cattle with tylosin. J Anim Sci 86:2385\u20132391","journal-title":"J Anim Sci"},{"key":"9634_CR9","doi-asserted-by":"publisher","first-page":"4407","DOI":"10.1128\/AEM.02799-06","volume":"73","author":"J Chen","year":"2007","unstructured":"Chen J, Yu Z, Michel FC Jr, Wittum T, Morrison M (2007) Development and application of real-time PCR assays for quantification of erm genes conferring resistance to macrolides\u2013lincosamides\u2013streptogramin B in livestock manure and manure management systems. Appl Environ Microbiol 73:4407\u20134416","journal-title":"Appl Environ Microbiol"},{"key":"9634_CR10","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1089\/mdr.2004.10.341","volume":"10","author":"E Leener De","year":"2004","unstructured":"De Leener E, Martel A, Decostere A, Haesebrouck F (2004) Distribution of the erm (B) gene, tetracycline resistance genes, and Tn1545-like transposons in macrolide- and lincosamide-resistant enterococci from pigs and humans. Microb Drug Resist 10:341\u2013345","journal-title":"Microb Drug Resist"},{"key":"9634_CR11","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1089\/mdr.2007.746","volume":"13","author":"HD Emborg","year":"2007","unstructured":"Emborg HD, Vigre H, Jensen VF, Vieira AR, Baggesen DL, Aarestrup FM (2007) Tetracycline consumption and occurrence of tetracycline resistance in Salmonella typhimurium phage types from Danish pigs. Microb Drug Resist 13:289\u2013294","journal-title":"Microb Drug Resist"},{"key":"9634_CR12","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1289\/ehp.8837","volume":"115","author":"MJ Gilchrist","year":"2007","unstructured":"Gilchrist MJ, Greko C, Wallinga DB, Beran GW, Riley DG, Thorne PS (2007) The potential role of concentrated animal feeding operations in infectious disease epidemics and antibiotic resistance. Environ Health Perspect 115:313\u2013316","journal-title":"Environ Health Perspect"},{"key":"9634_CR13","doi-asserted-by":"publisher","first-page":"1294","DOI":"10.1126\/science.321.5894.1294a","volume":"321","author":"R Goldburg","year":"2008","unstructured":"Goldburg R, Roach S, Wallinga D, Mellon M (2008) The risks of pigging out on antibiotics. Science 321:1294","journal-title":"Science"},{"key":"9634_CR14","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1002\/bit.21176","volume":"97","author":"R Iranpour","year":"2007","unstructured":"Iranpour R, Cox HH (2007) Evaluation of thermophilic anaerobic digestion processes for full-scale Class A biosolids disinfection at Hyperion treatment plant. Biotechnol Bioeng 97:19\u201339","journal-title":"Biotechnol Bioeng"},{"key":"9634_CR15","doi-asserted-by":"publisher","first-page":"7813","DOI":"10.1128\/AEM.01087-06","volume":"72","author":"A Jindal","year":"2006","unstructured":"Jindal A, Kocherginskaya S, Mehboob A, Robert M, Mackie RI, Raskin L, Zilles JL (2006) Antimicrobial use and resistance in swine waste treatment systems. Appl Environ Microbiol 72:7813\u20137820","journal-title":"Appl Environ Microbiol"},{"key":"9634_CR16","doi-asserted-by":"publisher","first-page":"4813","DOI":"10.1128\/AEM.00665-07","volume":"73","author":"S Koike","year":"2007","unstructured":"Koike S, Krapac IG, Oliver HD, Yannarell AC, Chee-Sanford JC, Aminov RI, Mackie RI (2007) Monitoring and source tracking of tetracycline resistance genes in lagoons and groundwater adjacent to swine production facilities over a 3-year period. Appl Environ Microbiol 73:4813\u20134823","journal-title":"Appl Environ Microbiol"},{"key":"9634_CR17","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1016\/j.chemosphere.2005.02.094","volume":"60","author":"AC Kolz","year":"2005","unstructured":"Kolz AC, Ong SK, Moorman TB (2005) Sorption of tylosin onto swine manure. Chemosphere 60:284\u2013289","journal-title":"Chemosphere"},{"key":"9634_CR18","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1146\/annurev.micro.55.1.709","volume":"55","author":"EV Koonin","year":"2001","unstructured":"Koonin EV, Makarova KS, Aravind L (2001) Horizontal gene transfer in prokaryotes: quantification and classification. Annu Rev Microbiol 55:709\u2013742","journal-title":"Annu Rev Microbiol"},{"key":"9634_CR19","doi-asserted-by":"publisher","first-page":"2970","DOI":"10.1128\/AEM.71.6.2970-2978.2005","volume":"71","author":"H Luo","year":"2005","unstructured":"Luo H, Wan K, Wang HH (2005) High-frequency conjugation system facilitates biofilm formation and pAM\u03b21 transmission by Lactococcus lactis. Appl Environ Microbiol 71:2970\u20132978","journal-title":"Appl Environ Microbiol"},{"key":"9634_CR20","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1080\/10495390600956953","volume":"17","author":"RI Mackie","year":"2006","unstructured":"Mackie RI, Koike S, Krapac I, Chee-Sanford J, Maxwell S, Aminov RI (2006) Tetracycline residues and tetracycline resistance genes in groundwater impacted by swine production facilities. Anim Biotechnol 17:157\u2013176","journal-title":"Anim Biotechnol"},{"key":"9634_CR21","doi-asserted-by":"publisher","first-page":"2893","DOI":"10.1016\/j.envpol.2009.05.051","volume":"157","author":"JL Martinez","year":"2009","unstructured":"Martinez JL (2009) Environmental pollution by antibiotics and by antibiotic resistance determinants. Environ Pollut 157:2893\u20132902","journal-title":"Environ Pollut"},{"key":"9634_CR22","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1089\/fpd.2006.0066","volume":"4","author":"AG Mathew","year":"2007","unstructured":"Mathew AG, Cissell R, Liamthong S (2007) Antibiotic resistance in bacteria associated with food animals: a United States perspective of livestock production. Foodborne Pathogens and Disease 4:115\u2013133","journal-title":"Foodborne Pathogens and Disease"},{"key":"9634_CR23","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1111\/j.1462-2920.2006.01190.x","volume":"9","author":"AJ Patterson","year":"2007","unstructured":"Patterson AJ, Colangeli R, Spigaglia P, Scott KP (2007) Distribution of specific tetracycline and erythromycin resistance genes in environmental samples assessed by macroarray detection. Environ Microbiol 9:703\u2013715","journal-title":"Environ Microbiol"},{"key":"9634_CR24","first-page":"446","volume":"47","author":"A Rajic","year":"2006","unstructured":"Rajic A, Reid-Smith R, Deckert AE, Dewey CE, McEwen SA (2006) Reported antibiotic use in 90 swine farms in Alberta. Can Vet J 47:446\u2013452","journal-title":"Can Vet J"},{"key":"9634_CR25","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/j.ijantimicag.2006.11.015","volume":"29","author":"OC Stine","year":"2007","unstructured":"Stine OC, Johnson JA, Keefer-Norris A, Perry KL, Tigno J, Qaiyumi S, Stine MS, Morris JG Jr (2007) Widespread distribution of tetracycline resistance genes in a confined animal feeding facility. Int J Antimicrob Agents 29:348\u2013352","journal-title":"Int J Antimicrob Agents"},{"key":"9634_CR26","doi-asserted-by":"publisher","first-page":"7173","DOI":"10.1128\/AEM.69.12.7173-7180.2003","volume":"69","author":"P Stroman","year":"2003","unstructured":"Stroman P, Muller CC, Sorensen KI (2003) Heat shock treatment increases the frequency of loss of an erythromycin resistance-encoding transposable element from the chromosome of Lactobacillus crispatus CHCC3692. Appl Environ Microbiol 69:7173\u20137180","journal-title":"Appl Environ Microbiol"},{"key":"9634_CR27","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1089\/10766290152045075","volume":"7","author":"M Sunde","year":"2001","unstructured":"Sunde M, Sorum H (2001) Self-transmissible multidrug resistance plasmids in Escherichia coli of the normal intestinal flora of healthy swine. Microb Drug Resist 7:191\u2013196","journal-title":"Microb Drug Resist"},{"key":"9634_CR28","unstructured":"Williams CM (2005) Development of environmentally superior technologies: phase 2 report for technology determinations per agreements between the Attorney General of North Carolina and Smithfield Foods, Premium Standard Farms, and Frontline Farmers. Available at \n                    http:\/\/www.cals.ncsu.edu\/waste_mgt\/smithfield_projects\/phase2report05\/phase2report.htm"},{"key":"9634_CR29","doi-asserted-by":"publisher","first-page":"S19","DOI":"10.1016\/S0924-8579(00)00301-0","volume":"16","author":"W Witte","year":"2000","unstructured":"Witte W (2000) Selective pressure by antibiotic use in livestock. Int J Antimicrob Agents 16:S19\u2013S24","journal-title":"Int J Antimicrob Agents"},{"key":"9634_CR30","first-page":"233","volume":"52","author":"KI Wolska","year":"2003","unstructured":"Wolska KI (2003) Horizontal DNA transfer between bacteria in the environment. Acta Microbiol Pol 52:233\u2013243","journal-title":"Acta Microbiol Pol"},{"key":"9634_CR31","doi-asserted-by":"publisher","first-page":"6926","DOI":"10.1128\/AEM.71.11.6926-6933.2005","volume":"71","author":"Z Yu","year":"2005","unstructured":"Yu Z, Michel FC Jr, Hansen G, Wittum T, Morrison M (2005) Development and application of real-time PCR assays for quantification of genes encoding tetracycline resistance. Appl Environ Microbiol 71:6926\u20136933","journal-title":"Appl Environ Microbiol"},{"key":"9634_CR32","doi-asserted-by":"crossref","first-page":"808","DOI":"10.2144\/04365ST04","volume":"36","author":"Z Yu","year":"2004","unstructured":"Yu Z, Morrison M (2004) Improved extraction of PCR-quality community DNA from digesta and fecal samples. BioTechniques 36:808\u2013812","journal-title":"BioTechniques"},{"key":"9634_CR33","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1007\/s00253-008-1829-z","volume":"82","author":"XX Zhang","year":"2009","unstructured":"Zhang XX, Zhang T, Fang HH (2009) Antibiotic resistance genes in water environment. Appl Microbiol Biotechnol 82:397\u2013414","journal-title":"Appl Microbiol Biotechnol"},{"key":"9634_CR34","doi-asserted-by":"publisher","first-page":"5366","DOI":"10.1128\/JCM.41.12.5366-5371.2003","volume":"41","author":"S Zhao","year":"2003","unstructured":"Zhao S, Qaiyumi S, Friedman S, Singh R, Foley SL, White DG, McDermott PF, Donkar T, Bolin C, Munro S, Baron EJ, Walker RD (2003) Characterization of Salmonella enterica serotype Newport isolated from humans and food animals. J Clin Microbiol 41:5366\u20135371","journal-title":"J Clin Microbiol"},{"key":"9634_CR35","doi-asserted-by":"publisher","first-page":"57","DOI":"10.2175\/106143005X41627","volume":"77","author":"J Zilles","year":"2005","unstructured":"Zilles J, Shimada T, Jindal A, Robert M, Raskin L (2005) Presence of macrolide\u2013lincosamide\u2013streptogramin B and tetracycline antimicrobials in swine waste treatment processes and amended soil. Water Environ Res 77:57\u201362","journal-title":"Water Environ Res"}],"container-title":["Microbial Ecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00248-010-9634-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00248-010-9634-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00248-010-9634-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00248-010-9634-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T16:34:07Z","timestamp":1581957247000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00248-010-9634-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2,6]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["9634"],"URL":"https:\/\/doi.org\/10.1007\/s00248-010-9634-5","relation":{},"ISSN":["0095-3628","1432-184X"],"issn-type":[{"value":"0095-3628","type":"print"},{"value":"1432-184X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2,6]]}}}