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In making these awards, the Journal and EBSA again sought to recognise publications which were already proving their impact. The studies recognised are diverse and highlight the vitality of biophysical science in the 2020s. They concern studies of (i) synaptic vesicles undergoing glutamate uptake, (ii) red blood cells under pressure and the effects of mechanically triggered calcium influx, and (iii) how ciliary beating, the resulting wave effects and downstream transport processes interrelate in trachea. 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