{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T01:19:16Z","timestamp":1790299156072,"version":"4.1.0"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T00:00:00Z","timestamp":1701993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T00:00:00Z","timestamp":1701993600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Immunogenetics"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1007\/s00251-023-01326-4","type":"journal-article","created":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T05:01:25Z","timestamp":1702011685000},"page":"15-25","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["The COVID-19 inflammation and high mortality mechanism trigger"],"prefix":"10.1007","volume":"76","author":[{"given":"Samuel","family":"Str\u00f3\u017c","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Kosiorek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Stasiak-Barmuta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,12,8]]},"reference":[{"issue":"6","key":"1326_CR1","doi-asserted-by":"publisher","first-page":"2827","DOI":"10.1007\/s00415-022-11050-w","volume":"269","author":"H Ari\u00f1o","year":"2022","unstructured":"Ari\u00f1o H, Heartshorne R, Michael BD, Nicholson TR, Vincent A, Pollak TA, Vogrig A (2022) Neuroimmune disorders in COVID-19. J Neurol 269(6):2827\u20132839","journal-title":"J Neurol"},{"issue":"6","key":"1326_CR2","doi-asserted-by":"publisher","first-page":"410","DOI":"10.3390\/bios12060410","volume":"12","author":"R Asghar","year":"2022","unstructured":"Asghar R, Rasheed M, Hassan J, Rafique M, Khan M, Deng Y (2022) Advancements in testing strategies for COVID-19. Biosensors (basel) 12(6):410","journal-title":"Biosensors (basel)"},{"issue":"4","key":"1326_CR3","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1007\/s00203-023-03480-5","volume":"205","author":"R Baghban","year":"2023","unstructured":"Baghban R, Ghasemian A, Mahmoodi S (2023) Nucleic acid-based vaccine platforms against the coronavirus disease 19 (COVID-19). Arch Microbiol 205(4):150","journal-title":"Arch Microbiol"},{"issue":"2","key":"1326_CR4","first-page":"237","volume":"95","author":"BJ Behers","year":"2022","unstructured":"Behers BJ, Patrick GA, Jones JM et al (2022) Myocarditis following COVID-19 vaccination: a systematic review of case reports. Yale J Biol Med 95(2):237\u2013247","journal-title":"Yale J Biol Med"},{"issue":"1","key":"1326_CR5","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1186\/s12929-022-00872-5","volume":"29","author":"AC Borczuk","year":"2022","unstructured":"Borczuk AC, Yantiss RK (2022) The pathogenesis of coronavirus-19 disease. J Biomed Sci 29(1):87","journal-title":"J Biomed Sci"},{"issue":"6","key":"1326_CR6","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.1007\/s43440-022-00424-6","volume":"74","author":"W Brola","year":"2022","unstructured":"Brola W, Wilski M (2022) Neurological consequences of COVID-19. Pharmacol Rep 74(6):1208\u20131222","journal-title":"Pharmacol Rep"},{"issue":"1","key":"1326_CR7","doi-asserted-by":"publisher","first-page":"1473","DOI":"10.1080\/07853890.2022.2076901","volume":"54","author":"D Castanares-Zapatero","year":"2022","unstructured":"Castanares-Zapatero D, Chalon P, Kohn L et al (2022) Pathophysiology and mechanism of long COVID: a comprehensive review. Ann Med 54(1):1473\u20131487","journal-title":"Ann Med"},{"issue":"10","key":"1326_CR8","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1038\/s41577-022-00762-9","volume":"22","author":"EM Conway","year":"2022","unstructured":"Conway EM, Mackman N, Warren RQ et al (2022) Understanding COVID-19-associated coagulopathy. Nat Rev Immunol 22(10):639\u2013649","journal-title":"Nat Rev Immunol"},{"issue":"18","key":"1326_CR9","doi-asserted-by":"publisher","first-page":"10881","DOI":"10.3390\/ijms231810881","volume":"23","author":"M Cosentino","year":"2022","unstructured":"Cosentino M, Marino F (2022) Understanding the pharmacology of COVID-19 mRNA vaccines: playing dice with the spike? Int J Mol Sci 23(18):10881","journal-title":"Int J Mol Sci"},{"issue":"22","key":"1326_CR10","doi-asserted-by":"publisher","first-page":"2097","DOI":"10.1056\/NEJMoa2202261","volume":"386","author":"L Dai","year":"2022","unstructured":"Dai L, Gao L, Tao L et al (2022) Efficacy and safety of the RBD-dimer-based COVID-19 vaccine ZF2001 in adults. N Engl J Med 386(22):2097\u20132111","journal-title":"N Engl J Med"},{"issue":"3","key":"1326_CR11","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1038\/s41579-022-00846-2","volume":"21","author":"HE Davis","year":"2023","unstructured":"Davis HE, McCorkell L, Vogel JM, Topol EJ (2023) Long COVID: major findings, mechanisms and recommendations. Nat Rev Microbiol 21(3):133\u2013146","journal-title":"Nat Rev Microbiol"},{"issue":"3","key":"1326_CR12","first-page":"119","volume":"70","author":"D Dmytriiev","year":"2021","unstructured":"Dmytriiev D, Dobrovanov O, Kralinsky K, Dmytriiev K, Melnychenko M (2021) A case report of successful experience of using adaptive support ventilation in the pediatric patient with viral interstitial pneumonia covid-19 positive. Lek Obz 70(3):119\u2013123","journal-title":"Lek Obz"},{"issue":"7","key":"1326_CR13","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1038\/s41581-022-00571-2","volume":"18","author":"E Dub\u00e9","year":"2022","unstructured":"Dub\u00e9 E, MacDonald N (2022) COVID-19 vaccine hesitancy. Nat Rev Nephrol 18(7):409\u2013410","journal-title":"Nat Rev Nephrol"},{"issue":"10","key":"1326_CR14","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.1161\/CIRCRESAHA.123.321878","volume":"132","author":"D Fairweather","year":"2023","unstructured":"Fairweather D, Beetler D, Florio D, Musigk D, Heidecker B, Cooper L (2023) COVID-19, myocarditis, and pericarditis. Circ Res 132(10):1302\u20131319","journal-title":"Circ Res"},{"issue":"1","key":"1326_CR15","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1080\/07853890.2022.2031274","volume":"54","author":"G Fernandes","year":"2022","unstructured":"Fernandes G, Inchakalody V, Merhi M et al (2022) Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics, and vaccines. Ann Med 54(1):524\u2013540","journal-title":"Ann Med"},{"issue":"12","key":"1326_CR16","first-page":"4535","volume":"26","author":"YW Fu","year":"2022","unstructured":"Fu YW, Xu HS, Liu SJ (2022) COVID-19 and neurodegenerative diseases. Eur Rev Med Pharmacol Sci 26(12):4535\u20134544","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"19","key":"1326_CR17","doi-asserted-by":"publisher","first-page":"12422","DOI":"10.3390\/ijerph191912422","volume":"19","author":"P Gao","year":"2022","unstructured":"Gao P, Liu J, Liu M (2022) Effect of COVID-19 vaccines on reducing the risk of long COVID in the real world: a systematic review and meta-analysis. Int J Environ Res Public Health 19(19):12422","journal-title":"Int J Environ Res Public Health"},{"issue":"7","key":"1326_CR18","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1007\/s40264-022-01186-z","volume":"45","author":"R Harpaz","year":"2022","unstructured":"Harpaz R, DuMouchel W, van Manen R et al (2022) Signaling COVID-19 vaccine adverse events. Drug Saf 45(7):765\u2013780","journal-title":"Drug Saf"},{"issue":"47","key":"1326_CR19","doi-asserted-by":"publisher","first-page":"6716","DOI":"10.3748\/wjg.v28.i47.6716","volume":"28","author":"WS Hu","year":"2022","unstructured":"Hu WS, Jiang FY, Shu W, Zhao R, Cao JM, Wang DP (2022) Liver injury in COVID-19: a minireview. World J Gastroenterol 28(47):6716\u20136731","journal-title":"World J Gastroenterol"},{"issue":"3","key":"1326_CR20","doi-asserted-by":"publisher","first-page":"447","DOI":"10.25122\/jml-2022-0168","volume":"16","author":"U Kamilova","year":"2023","unstructured":"Kamilova U, Ermekbaeva A, Nuritdinov N, Khamraev A, Zakirova G (2023) Occurrence of comorbid diseases in patients after COVID-19. J Med Life 16(3):447\u2013450","journal-title":"J Med Life"},{"issue":"7931","key":"1326_CR21","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1038\/s41586-022-05282-z","volume":"610","author":"J Kee","year":"2022","unstructured":"Kee J, Thudium S, Renner DM et al (2022) SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry. Nature 610(7931):381\u2013388","journal-title":"Nature"},{"issue":"4","key":"1326_CR22","doi-asserted-by":"publisher","first-page":"305","DOI":"10.18865\/ed.32.4.305","volume":"32","author":"M Khare","year":"2022","unstructured":"Khare M, Zimmermann K, Kazungu F et al (2022) COVID-19 vaccine attitudes and barriers among unvaccinated residents in rural Northern\/Central Illinois. Ethn Dis 32(4):305\u2013314","journal-title":"Ethn Dis"},{"issue":"2","key":"1326_CR23","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1007\/s00405-022-07689-w","volume":"280","author":"HN Krishnakumar","year":"2023","unstructured":"Krishnakumar HN, Momtaz DA, Sherwani A et al (2023) Pathogenesis and progression of anosmia and dysgeusia during the COVID-19 pandemic. Eur Arch Otorhinolaryngol 280(2):505\u2013509","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"11","key":"1326_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2022.110955","volume":"39","author":"L Leng","year":"2022","unstructured":"Leng L, Ma J, Zhang PP et al (2022) Spatial region-resolved proteome map reveals mechanism of COVID-19-associated heart injury. Cell Rep 39(11):110955","journal-title":"Cell Rep"},{"issue":"5","key":"1326_CR25","doi-asserted-by":"publisher","first-page":"816","DOI":"10.3390\/cells12050816","volume":"12","author":"A Leng","year":"2023","unstructured":"Leng A, Shah M, Ahmad SA et al (2023) Pathogenesis underlying neurological manifestations of long COVID syndrome and potential therapeutics. Cells 12(5):816","journal-title":"Cells"},{"issue":"1","key":"1326_CR26","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1038\/s41392-022-01043-6","volume":"7","author":"X Li","year":"2022","unstructured":"Li X, Zhang Z, Wang Z, Guti\u00e9rrez-Castrell\u00f3n P, Shi H (2022) Cell deaths: involvement in the pathogenesis and intervention therapy of COVID-19. Signal Transduct Target Ther 7(1):186","journal-title":"Signal Transduct Target Ther"},{"issue":"3","key":"1326_CR27","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1152\/ajpheart.00204.2022","volume":"323","author":"C Narasimhulu","year":"2022","unstructured":"Narasimhulu C, Singla D (2022) Mechanisms of COVID-19 pathogenesis in diabetes. Am J Physiol Heart Circ Physiol 323(3):403\u2013420","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"3","key":"1326_CR28","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1007\/s10900-022-01080-w","volume":"47","author":"MC Navin","year":"2022","unstructured":"Navin MC, Oberleitner LM, Lucia VC et al (2022) COVID-19 vaccine hesitancy among healthcare personnel who generally accept vaccines. J Community Health 47(3):519\u2013529","journal-title":"J Community Health"},{"issue":"15","key":"1326_CR29","doi-asserted-by":"publisher","first-page":"8210","DOI":"10.3390\/ijms23158210","volume":"23","author":"D Oatis","year":"2022","unstructured":"Oatis D, Simon-Repolski E, Balta C et al (2022) Cellular and molecular mechanism of pulmonary fibrosis post-COVID-19: focus on galectin-1, -3, -8, -9. Int J Mol Sci 23(15):8210","journal-title":"Int J Mol Sci"},{"issue":"6","key":"1326_CR30","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1111\/andr.13199","volume":"10","author":"S Olana","year":"2022","unstructured":"Olana S, Mazzilli R, Salerno G et al (2022) 4BNT162b2 mRNA COVID-19 vaccine and semen: what do we know? Andrology 10(6):1023\u20131029","journal-title":"Andrology"},{"key":"1326_CR31","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2021-069445","volume":"378","author":"J Pillay","year":"2022","unstructured":"Pillay J, Gaudet L, Wingert A et al (2022) Incidence, risk factors, natural history, and hypothesised mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review. BMJ 378:e069445","journal-title":"BMJ"},{"issue":"6","key":"1326_CR32","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1016\/j.amjms.2021.10.012","volume":"363","author":"J Pl\u00e1\u0161ek","year":"2022","unstructured":"Pl\u00e1\u0161ek J, Gumulec J, M\u00e1ca J et al (2022) COVID-19 associated coagulopathy: mechanisms and host-directed treatment. Am J Med Sci 363(6):465\u2013475","journal-title":"Am J Med Sci"},{"issue":"49","key":"1326_CR33","doi-asserted-by":"publisher","first-page":"7032","DOI":"10.1016\/j.vaccine.2022.10.012","volume":"40","author":"S Rhodes","year":"2022","unstructured":"Rhodes S, Smith N, Evans T, White R (2022) Identifying COVID-19 optimal vaccine dose using mathematical immunostimulation\/immunodynamic modelling. Vaccine 40(49):7032\u20137041","journal-title":"Vaccine"},{"key":"1326_CR34","doi-asserted-by":"crossref","unstructured":"Rodr\u00edguez Y, Rojas M, Beltr\u00e1n S et al (2022) Autoimmune and autoinflammatory conditions after COVID-19 vaccination. New case reports and updated literature review. J Autoimmun 132:102898","DOI":"10.1016\/j.jaut.2022.102898"},{"issue":"2","key":"1326_CR35","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.amjms.2022.01.022","volume":"364","author":"JK Salabei","year":"2022","unstructured":"Salabei JK, Asnake ZT, Ismail ZH et al (2022) COVID-19 and the cardiovascular system: an update. Am J Med Sci 364(2):139\u2013147","journal-title":"Am J Med Sci"},{"issue":"5","key":"1326_CR36","doi-asserted-by":"publisher","first-page":"2185","DOI":"10.1007\/s11845-021-02807-9","volume":"191","author":"L Schaler","year":"2022","unstructured":"Schaler L, Wingfield M (2022) COVID-19 vaccine \u2013 can it affect fertility? Ir J Med Sci 191(5):2185\u20132187","journal-title":"Ir J Med Sci"},{"issue":"7","key":"1326_CR37","doi-asserted-by":"publisher","first-page":"969","DOI":"10.7326\/M21-4905","volume":"175","author":"MC Sneller","year":"2022","unstructured":"Sneller MC, Liang CJ, Marques AR et al (2022) A longitudinal study of COVID-19 sequelae and immunity: baseline findings. Ann Intern Med 175(7):969\u2013979","journal-title":"Ann Intern Med"},{"issue":"8","key":"1326_CR38","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0272426","volume":"17","author":"A Thorpe","year":"2022","unstructured":"Thorpe A, Fagerlin A, Butler J et al (2022) Communicating about COVID-19 vaccine development and safety. PLoS ONE 17(8):e0272426","journal-title":"PLoS ONE"},{"issue":"9","key":"1326_CR39","doi-asserted-by":"publisher","first-page":"2119","DOI":"10.1007\/s11095-022-03323-w","volume":"39","author":"S Upreti","year":"2022","unstructured":"Upreti S, Samant M (2022) A review on immunological responses to SARS-CoV-2 and various COVID-19 vaccine regimens. Pharm Res 39(9):2119\u20132134","journal-title":"Pharm Res"},{"key":"1326_CR40","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2022.102608","volume":"76","author":"A Vanderheiden","year":"2022","unstructured":"Vanderheiden A, Klein RS (2022) Neuroinflammation and COVID-19. Curr Opin Neurobiol 76:102608","journal-title":"Curr Opin Neurobiol"},{"issue":"1","key":"1326_CR41","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1186\/s12889-022-13882-7","volume":"22","author":"T Wyte-Lake","year":"2022","unstructured":"Wyte-Lake T, Levy C, Hovsepian S, Mudoh Y, Schmitz C, Dobalian A (2022) COVID-19 vaccine adoption and hesitancy among older Veterans. BMC Public Health 22(1):1532","journal-title":"BMC Public Health"},{"key":"1326_CR42","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.bbi.2022.04.001","volume":"103","author":"CP Yang","year":"2022","unstructured":"Yang CP, Chang CM, Yang CC, Pariante CM, Su KP (2022) Long COVID and long chain fatty acids (LCFAs): psychoneuroimmunity implication of omega-3 LCFAs in delayed consequences of COVID-19. Brain Behav Immun 103:19\u201327","journal-title":"Brain Behav Immun"},{"issue":"5","key":"1326_CR43","doi-asserted-by":"publisher","first-page":"2937","DOI":"10.1002\/ehf2.14003","volume":"9","author":"G Zhang","year":"2022","unstructured":"Zhang G, Cui X, Zhang L et al (2022) Uncovering the genetic links of SARS-CoV-2 infections on heart failure co-morbidity by a systems biology approach. ESC Heart Fail 9(5):2937\u20132954","journal-title":"ESC Heart Fail"},{"issue":"5","key":"1326_CR44","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1038\/s41575-022-00698-4","volume":"20","author":"F Zhang","year":"2023","unstructured":"Zhang F, Lau RI, Liu Q et al (2023a) Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications. Nat Rev Gastroenterol Hepatol 20(5):323\u2013337","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"2","key":"1326_CR45","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1111\/all.15593","volume":"78","author":"HP Zhang","year":"2023","unstructured":"Zhang HP, Sun YL, Wang YF et al (2023b) Recent developments in the immunopathology of COVID-19. Allergy 78(2):369\u2013388","journal-title":"Allergy"},{"key":"1326_CR46","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.898192","volume":"13","author":"Z Zhou","year":"2022","unstructured":"Zhou Z, Zhu Z, Chu M (2022) Role of COVID-19 vaccines in SARS-CoV-2 variants. Front Immunol 13:898192","journal-title":"Front Immunol"}],"container-title":["Immunogenetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00251-023-01326-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00251-023-01326-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00251-023-01326-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T13:04:47Z","timestamp":1706706287000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00251-023-01326-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,8]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["1326"],"URL":"https:\/\/doi.org\/10.1007\/s00251-023-01326-4","relation":{},"ISSN":["0093-7711","1432-1211"],"issn-type":[{"value":"0093-7711","type":"print"},{"value":"1432-1211","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,8]]},"assertion":[{"value":"27 September 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 December 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}