{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:20:26Z","timestamp":1790403626812,"version":"4.1.0"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,11,15]],"date-time":"2017-11-15T00:00:00Z","timestamp":1510704000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100004504","name":"Lietuvos Mokslo Taryba","doi-asserted-by":"publisher","award":["MIP-039\/2015"],"award-info":[{"award-number":["MIP-039\/2015"]}],"id":[{"id":"10.13039\/501100004504","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Microbiol Biotechnol"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1007\/s00253-017-8622-9","type":"journal-article","created":{"date-parts":[[2017,11,15]],"date-time":"2017-11-15T07:10:54Z","timestamp":1510729854000},"page":"185-198","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Generation in yeast and antigenic characterization of hepatitis E virus capsid protein virus-like particles"],"prefix":"10.1007","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2996-229X","authenticated-orcid":false,"given":"Martynas","family":"Simanavicius","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulius Lukas","family":"Tamosiunas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasa","family":"Petraityte-Burneikiene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reimar","family":"Johne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer G.","family":"Ulrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurelija","family":"Zvirbliene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indre","family":"Kucinskaite-Kodze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,11,15]]},"reference":[{"issue":"1","key":"8622_CR1","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1038\/nrgastro.2012.187","volume":"10","author":"R Aggarwal","year":"2012","unstructured":"Aggarwal R (2012) Diagnosis of hepatitis E. Nat Rev Gastroenterol Hepatol 10(1):24\u201333. https:\/\/doi.org\/10.1038\/nrgastro.2012.187","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"12","key":"8622_CR2","doi-asserted-by":"publisher","first-page":"2889","DOI":"10.4315\/0362-028X-70.12.2889","volume":"70","author":"M Bouwknegt","year":"2007","unstructured":"Bouwknegt M, Lodder-Verschoor F, van der Poel WHM, Rutjes SA, de Roda Husman AM (2007) Hepatitis E virus RNA in commercial porcine livers in The Netherlands. J Food Prot 70(12):2889\u20132895. https:\/\/doi.org\/10.4315\/0362-028X-70.12.2889","journal-title":"J Food Prot"},{"issue":"8","key":"8622_CR3","doi-asserted-by":"publisher","first-page":"e17","DOI":"10.1038\/emi.2012.7","volume":"1","author":"D Cao","year":"2012","unstructured":"Cao D, Meng X-J (2012) Molecular biology and replication of hepatitis E virus. Emerg Microbes Infect 1(8):e17. https:\/\/doi.org\/10.1038\/emi.2012.7","journal-title":"Emerg Microbes Infect"},{"issue":"1-2","key":"8622_CR4","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.jviromet.2013.03.010","volume":"190","author":"P Dremsek","year":"2013","unstructured":"Dremsek P, Joel S, Baechlein C, Pavio N, Schielke A, Ziller M, D\u00fcrrwald R, Renner C, Groschup MH, Johne R, Krumbholz A, Ulrich RG (2013) Hepatitis E virus seroprevalence of domestic pigs in Germany determined by a novel in-house and two reference ELISAs. J Virol Methods 190(1-2):11\u201316. https:\/\/doi.org\/10.1016\/j.jviromet.2013.03.010","journal-title":"J Virol Methods"},{"issue":"2","key":"8622_CR5","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1007\/s00430-011-0221-2","volume":"201","author":"P Dremsek","year":"2012","unstructured":"Dremsek P, Wenzel JJ, Johne R, Ziller M, Hofmann J, Groschup MH, Werdermann S, Mohn U, Dorn S, Motz M, Mertens M, Jilg W, Ulrich RG (2012) Seroprevalence study in forestry workers from eastern Germany using novel genotype 3- and rat hepatitis E virus-specific immunoglobulin G ELISAs. Med Microbiol Immunol 201(2):189\u2013200. https:\/\/doi.org\/10.1007\/s00430-011-0221-2","journal-title":"Med Microbiol Immunol"},{"issue":"10","key":"8622_CR6","doi-asserted-by":"publisher","first-page":"1654","DOI":"10.3201\/eid1810.111756","volume":"18","author":"MS Faber","year":"2012","unstructured":"Faber MS, Wenzel JJ, Jilg W, Thamm M, H\u00f6hle M, Stark K (2012) Hepatitis E virus seroprevalence among adults, Germany. Emerg Infect Dis 18(10):1654\u20131657. https:\/\/doi.org\/10.3201\/eid1810.111756","journal-title":"Emerg Infect Dis"},{"issue":"5","key":"8622_CR7","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1038\/cr.2015.34","volume":"25","author":"Y Gu","year":"2015","unstructured":"Gu Y, Tang X, Zhang X, Song C, Zheng M, Wang K, Zhang J, Ng M-H, Hew C-L, Li S, Xia N, Sivaraman J (2015) Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody. Cell Res 25(5):604\u2013620. https:\/\/doi.org\/10.1038\/cr.2015.34","journal-title":"Cell Res"},{"issue":"31","key":"8622_CR8","doi-asserted-by":"publisher","first-page":"12992","DOI":"10.1073\/pnas.0904848106","volume":"106","author":"TSY Guu","year":"2009","unstructured":"Guu TSY, Liu Z, Ye Q, Mata DA, Li K, Yin C, Zhang J, Tao YJ (2009) Structure of the hepatitis E virus-like particle suggests mechanisms for virus assembly and receptor binding. Proc Natl Acad Sci U S A 106(31):12992\u201312997. https:\/\/doi.org\/10.1073\/pnas.0904848106","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"8","key":"8622_CR9","doi-asserted-by":"publisher","first-page":"211","DOI":"10.3390\/v8080211","volume":"8","author":"J Hartl","year":"2016","unstructured":"Hartl J, Otto B, Madden R, Webb G, Woolson K, Kriston L, Vettorazzi E, Lohse A, Dalton H, Pischke S (2016) Hepatitis E Seroprevalence in Europe: a meta-analysis. Viruses 8(8):211. https:\/\/doi.org\/10.3390\/v8080211","journal-title":"Viruses"},{"issue":"5","key":"8622_CR10","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1007\/s11373-007-9172-4","volume":"14","author":"J He","year":"2007","unstructured":"He J, Kuschner RA, Dewar V, Voet P, Asher LV, Vaughn DW (2007) Characterization of monoclonal antibodies to hepatitis E virus (HEV) capsid protein and identification of binding activity. J Biomed Sci 14(5):555\u2013563. https:\/\/doi.org\/10.1007\/s11373-007-9172-4","journal-title":"J Biomed Sci"},{"issue":"9","key":"8622_CR11","doi-asserted-by":"publisher","first-page":"1452","DOI":"10.3201\/eid1609.100444","volume":"16","author":"R Johne","year":"2010","unstructured":"Johne R, Heckel G, Plenge-B\u00f6nig A, Kindler E, Maresch C, Reetz J, Schielke A, Ulrich RG (2010) Novel hepatitis E virus genotype in Norway rats, Germany. Emerg Infect Dis 16(9):1452\u20131455. https:\/\/doi.org\/10.3201\/eid1609.100444","journal-title":"Emerg Infect Dis"},{"issue":"14","key":"8622_CR12","doi-asserted-by":"publisher","first-page":"4225","DOI":"10.1128\/AEM.00951-16","volume":"82","author":"R Johne","year":"2016","unstructured":"Johne R, Trojnar E, Filter M, Hofmann J (2016) Thermal stability of hepatitis E virus as estimated by a cell culture method. Appl Environ Microbiol 82(14):4225\u20134231. https:\/\/doi.org\/10.1128\/AEM.00951-16","journal-title":"Appl Environ Microbiol"},{"issue":"2","key":"8622_CR13","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1111\/jvh.12445","volume":"23","author":"MS Khuroo","year":"2016","unstructured":"Khuroo MS, Khuroo MS (2016) Hepatitis E: an emerging global disease\u2014from discovery towards control and cure. J Viral Hepat 23(2):68\u201379. https:\/\/doi.org\/10.1111\/jvh.12445","journal-title":"J Viral Hepat"},{"issue":"31","key":"8622_CR14","doi-asserted-by":"publisher","first-page":"7030","DOI":"10.3748\/wjg.v22.i31.7030","volume":"22","author":"MS Khuroo","year":"2016","unstructured":"Khuroo MS, Khuroo MS, Khuroo NS (2016) Hepatitis E: discovery, global impact, control and cure. World J Gastroenterol 22(31):7030\u20137045. https:\/\/doi.org\/10.3748\/wjg.v22.i31.7030","journal-title":"World J Gastroenterol"},{"key":"8622_CR15","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.jviromet.2016.03.004","volume":"233","author":"T Kobayashi","year":"2016","unstructured":"Kobayashi T, Takahashi M, Tanggis M, Jirintai S, Nagashima S, Nishizawa T, Okamoto H (2016) Characterization and epitope mapping of monoclonal antibodies raised against rat hepatitis E virus capsid protein: an evaluation of their neutralizing activity in a cell culture system. J Virol Methods 233:78\u201388. https:\/\/doi.org\/10.1016\/j.jviromet.2016.03.004","journal-title":"J Virol Methods"},{"issue":"5517","key":"8622_CR16","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1038\/256495a0","volume":"256","author":"G K\u00f6hler","year":"1975","unstructured":"K\u00f6hler G, Milstein C (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256(5517):495\u2013497. https:\/\/doi.org\/10.1038\/256495a0","journal-title":"Nature"},{"issue":"3","key":"8622_CR17","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1007\/s11262-007-0127-7","volume":"35","author":"I Kucinskaite","year":"2007","unstructured":"Kucinskaite I, Juozapaitis M, Serva A, Zvirbliene A, Johnson N, Staniulis J, Fooks AR, M\u00fcller T, Sasnauskas K, Ulrich RG (2007) Antigenic characterisation of yeast-expressed lyssavirus nucleoproteins. Virus Genes 35(3):521\u2013529. https:\/\/doi.org\/10.1007\/s11262-007-0127-7","journal-title":"Virus Genes"},{"key":"8622_CR18","doi-asserted-by":"crossref","unstructured":"Kupferschmidt K (2016) Europe\u2019s new hepatitis problem. Science (80-):353:862\u2013863","DOI":"10.1126\/science.353.6302.862"},{"issue":"2","key":"8622_CR19","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1053\/j.gastro.2015.10.048","volume":"150","author":"G-H Lee","year":"2016","unstructured":"Lee G-H, Tan B-H, Chi-Yuan Teo E, Lim S-G, Dan Y-Y, Wee A, Kim Aw PP, Zhu Y, Hibberd ML, Tan C-K, Purdy MA, Teo C-G (2016) Chronic infection with camelid hepatitis E virus in a liver transplant recipient who regularly consumes camel meat and milk. Gastroenterology 150(2):355\u2013357.e3. https:\/\/doi.org\/10.1053\/j.gastro.2015.10.048","journal-title":"Gastroenterology"},{"issue":"5","key":"8622_CR20","doi-asserted-by":"publisher","first-page":"3400","DOI":"10.1074\/jbc.M410361200","volume":"280","author":"S-W Li","year":"2005","unstructured":"Li S-W, Zhang J, He Z-Q, Gu Y, Liu R-S, Lin J, Chen Y-X, Ng M-H, Xia N-S (2005a) Mutational analysis of essential interactions involved in the assembly of hepatitis E virus capsid. J Biol Chem 280(5):3400\u20133406. https:\/\/doi.org\/10.1074\/jbc.M410361200","journal-title":"J Biol Chem"},{"issue":"8","key":"8622_CR21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000537","volume":"5","author":"S Li","year":"2009","unstructured":"Li S, Tang X, Seetharaman J, Yang C, Gu Y, Zhang J, Du H, Shih JWK, Hew C-L, Sivaraman J, Xia N (2009) Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus\u2013host interaction. PLoS Pathog 5(8):e1000537. https:\/\/doi.org\/10.1371\/journal.ppat.1000537","journal-title":"PLoS Pathog"},{"issue":"22","key":"8622_CR22","doi-asserted-by":"publisher","first-page":"2893","DOI":"10.1016\/j.vaccine.2004.11.064","volume":"23","author":"SW Li","year":"2005","unstructured":"Li SW, Zhang J, Li YM, SH O, Huang GY, He ZQ, Ge SX, Xian YL, Pang SQ, Ng MH, Xia NS (2005b) A bacterially expressed particulate hepatitis E vaccine: antigenicity, immunogenicity and protectivity on primates. Vaccine 23(22):2893\u20132901. https:\/\/doi.org\/10.1016\/j.vaccine.2004.11.064","journal-title":"Vaccine"},{"issue":"10","key":"8622_CR23","doi-asserted-by":"crossref","first-page":"7207","DOI":"10.1128\/JVI.71.10.7207-7213.1997","volume":"71","author":"T-C Li","year":"1997","unstructured":"Li T-C, Yamakawa Y, Suzuki K, Tatsumi M, Azeez Razak MA, Uchida T, Takeda N, Miyamura T (1997) Expression and self-assembly of empty virus-like particles of hepatitis E virus. J Virol 71(10):7207\u20137213","journal-title":"J Virol"},{"issue":"12","key":"8622_CR24","doi-asserted-by":"publisher","first-page":"2830","DOI":"10.1099\/vir.0.034835-0","volume":"92","author":"T-C Li","year":"2011","unstructured":"Li T-C, Yoshimatsu K, Yasuda SP, Arikawa J, Koma T, Kataoka M, Ami Y, Suzaki Y, Mai LTQ, Hoa NT, Yamashiro T, Hasebe F, Takeda N, Wakita T (2011) Characterization of self-assembled virus-like particles of rat hepatitis E virus generated by recombinant baculoviruses. J Gen Virol 92(12):2830\u20132837. https:\/\/doi.org\/10.1099\/vir.0.034835-0","journal-title":"J Gen Virol"},{"issue":"8","key":"8622_CR25","doi-asserted-by":"publisher","first-page":"2962","DOI":"10.3390\/ijms11082962","volume":"11","author":"J-H Liang","year":"2010","unstructured":"Liang J-H, Dai X, Dong C, Meng J-H (2010) A single amino acid substitution changes antigenicity of ORF2-encoded proteins of hepatitis E virus. Int J Mol Sci 11(8):2962\u20132975. https:\/\/doi.org\/10.3390\/ijms11082962","journal-title":"Int J Mol Sci"},{"issue":"2","key":"8622_CR26","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1006\/viro.2001.1093","volume":"288","author":"J Meng","year":"2001","unstructured":"Meng J, Dai X, Chang JC, Lopareva E, Pillot J, Fields HA, Khudyakov YE (2001) Identification and characterization of the neutralization epitope(s) of the hepatitis E virus. Virology 288(2):203\u2013211. https:\/\/doi.org\/10.1006\/viro.2001.1093","journal-title":"Virology"},{"issue":"1","key":"8622_CR27","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.virusres.2011.03.015","volume":"161","author":"Y Mori","year":"2011","unstructured":"Mori Y, Matsuura Y (2011) Structure of hepatitis E viral particle. Virus Res 161(1):59\u201364. https:\/\/doi.org\/10.1016\/j.virusres.2011.03.015","journal-title":"Virus Res"},{"key":"8622_CR28","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01419","volume":"7","author":"Y Nan","year":"2016","unstructured":"Nan Y, Zhang Y-J (2016) Molecular biology and infection of hepatitis E virus. Front Microbiol 7:1419. https:\/\/doi.org\/10.3389\/fmicb.2016.01419","journal-title":"Front Microbiol"},{"key":"8622_CR29","doi-asserted-by":"publisher","unstructured":"Packer NH, Ball MS, Devine PL, Patton WF (2009) Detection of glycoproteins in gels and blots. Protein Protoc Handbook:555\u2013568. https:\/\/doi.org\/10.1385\/1-59259-169-8:761","DOI":"10.1385\/1-59259-169-8:761"},{"issue":"17","key":"8622_CR30","doi-asserted-by":"publisher","first-page":"8011","DOI":"10.1128\/JVI.74.17.8011-8017.2000","volume":"74","author":"MA Riddell","year":"2000","unstructured":"Riddell MA, Li F, Anderson DA (2000) Identification of immunodominant and conformational epitopes in the capsid protein of hepatitis E virus by using monoclonal antibodies. J Virol 74(17):8011\u20138017. https:\/\/doi.org\/10.1128\/JVI.74.17.8011-8017.2000","journal-title":"J Virol"},{"key":"8622_CR31","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.vetmic.2017.07.001","volume":"208","author":"R Ryll","year":"2017","unstructured":"Ryll R, Bernstein S, Heuser E, Schlegel M, Dremsek P, Zumpe M, Wolf S, P\u00e9pin M, Bajomi D, M\u00fcller G, Heiberg A-C, Spahr C, Lang J, Groschup MH, Ansorge H, Freise J, Guenther S, Baert K, Ruiz-Fons F, Pikula J, Knap N, Tsakmakidis \u0399, Dovas C, Zanet S, Imholt C, Heckel G, Johne R, Ulrich RG (2017) Detection of rat hepatitis E virus in wild Norway rats (Rattus norvegicus) and black rats (Rattus rattus) from 11 European countries. Vet Microbiol 208:58\u201368. https:\/\/doi.org\/10.1016\/j.vetmic.2017.07.001","journal-title":"Vet Microbiol"},{"issue":"1","key":"8622_CR32","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1002\/jmv.2120","volume":"66","author":"D Samuel","year":"2002","unstructured":"Samuel D, Sasnauskas K, Jin L, Beard S, Zvirbliene A, Gedvilaite A, Cohen B (2002) High level expression of recombinant mumps nucleoprotein in Saccharomyces cerevisiae and its evaluation in mumps IgM serology. J Med Virol 66(1):123\u2013130. https:\/\/doi.org\/10.1002\/jmv.2120","journal-title":"J Med Virol"},{"issue":"3","key":"8622_CR33","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1515\/BC.1999.050","volume":"380","author":"K Sasnauskas","year":"1999","unstructured":"Sasnauskas K, Buzaite O, Vogel F, Jandrig B, Razanskas R, Staniulis J, Scherneck S, Kr\u00fcger DH, Ulrich R (1999) Yeast cells allow high-level expression and formation of polyomavirus-like particles. Biol Chem 380(3):381\u2013386. https:\/\/doi.org\/10.1515\/BC.1999.050","journal-title":"Biol Chem"},{"issue":"1","key":"8622_CR34","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1186\/1743-422X-6-58","volume":"6","author":"A Schielke","year":"2009","unstructured":"Schielke A, Sachs K, Lierz M, Appel B, Jansen A, Johne R (2009) Detection of hepatitis E virus in wild boars of rural and urban regions in Germany and whole genome characterization of an endemic strain. Virol J 6(1):58. https:\/\/doi.org\/10.1186\/1743-422X-6-58","journal-title":"Virol J"},{"issue":"12","key":"8622_CR35","doi-asserted-by":"publisher","first-page":"5548","DOI":"10.1128\/JVI.74.12.5548-5555.2000","volume":"74","author":"DJ Schofield","year":"2000","unstructured":"Schofield DJ, Glamann J, Emerson SU, Purcell RH (2000) Identification by phage display and characterization of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein. J Virol 74(12):5548\u20135555. https:\/\/doi.org\/10.1128\/JVI.74.12.5548-5555.2000","journal-title":"J Virol"},{"issue":"11","key":"8622_CR36","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.1292\/jvms.16-0200","volume":"78","author":"K Shimizu","year":"2016","unstructured":"Shimizu K, Hamaguchi S, Ngo CC, Li T-C, Ando S, Yoshimatsu K, Yasuda SP, Koma T, Isozumi R, Tsuda Y, Fujita H, Pham TT, MQ LE, Dang AD, Nguyen TQ, Yoshida L-M, Ariyoshi K, Arikawa J (2016) Serological evidence of infection with rodent-borne hepatitis E virus HEV-C1 or antigenically related virus in humans. J Vet Med Sci 78(11):1677\u20131681. https:\/\/doi.org\/10.1292\/jvms.16-0200","journal-title":"J Vet Med Sci"},{"issue":"Pt_10","key":"8622_CR37","doi-asserted-by":"publisher","first-page":"2223","DOI":"10.1099\/vir.0.068429-0","volume":"95","author":"DB Smith","year":"2014","unstructured":"Smith DB, Simmonds P, International Committee on Taxonomy of Viruses Hepeviridae Study Groupmembers of the IC on the T of VHS, Jameel S, Emerson SU, Harrison TJ, Meng X-J, Okamoto H, Van der Poel WHM, Purdy MA (2014) Consensus proposals for classification of the family Hepeviridae. J Gen Virol 95(Pt_10):2223\u20132232. https:\/\/doi.org\/10.1099\/vir.0.068429-0","journal-title":"J Gen Virol"},{"issue":"3","key":"8622_CR38","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1007\/s00430-017-0503-4","volume":"206","author":"FM Sommerkorn","year":"2017","unstructured":"Sommerkorn FM, Schauer B, Schreiner T, Fickenscher H, Krumbholz A (2017) Performance of Hepatitis E Virus (HEV)-antibody tests: a comparative analysis based on samples from individuals with direct contact to domestic pigs or wild boar in Germany. Med Microbiol Immunol 206(3):277\u2013286. https:\/\/doi.org\/10.1007\/s00430-017-0503-4","journal-title":"Med Microbiol Immunol"},{"issue":"4","key":"8622_CR39","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1007\/s00705-008-0045-6","volume":"153","author":"M Takahashi","year":"2008","unstructured":"Takahashi M, Hoshino Y, Tanaka T, Takahashi H, Nishizawa T, Okamoto H (2008) Production of monoclonal antibodies against hepatitis E virus capsid protein and evaluation of their neutralizing activity in a cell culture system. Arch Virol 153(4):657\u2013666. https:\/\/doi.org\/10.1007\/s00705-008-0045-6","journal-title":"Arch Virol"},{"issue":"5","key":"8622_CR40","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1159\/000353112","volume":"56","author":"PL Tamo\u0161i\u016bnas","year":"2013","unstructured":"Tamo\u0161i\u016bnas PL, Simutis K, Kodz\u0117 I, Firantien\u0117 R, Emu\u017eyt\u0117 R, Petraityt\u0117-Burneikien\u0117 R, \u017dvirblien\u0117 A, Sasnauskas K (2013) Production of human parvovirus 4 VP2 virus-like particles in yeast and their evaluation as an antigen for detection of virus-specific antibodies in human serum. Intervirology 56(5):271\u2013277. https:\/\/doi.org\/10.1159\/000353112","journal-title":"Intervirology"},{"issue":"30","key":"8622_CR41","doi-asserted-by":"publisher","first-page":"3504","DOI":"10.1016\/j.vaccine.2015.05.065","volume":"33","author":"Z-M Tang","year":"2015","unstructured":"Tang Z-M, Tang M, Zhao M, Wen G-P, Yang F, Cai W, Wang S-L, Zheng Z-Z, Xia N-S (2015) A novel linear neutralizing epitope of hepatitis E virus. Vaccine 33(30):3504\u20133511. https:\/\/doi.org\/10.1016\/j.vaccine.2015.05.065","journal-title":"Vaccine"},{"issue":"7","key":"8622_CR42","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1089\/fpd.2012.1141","volume":"9","author":"S Wacheck","year":"2012","unstructured":"Wacheck S, Werres C, Mohn U, Dorn S, Soutschek E, Fredriksson-Ahomaa M, M\u00e4rtlbauer E (2012) Detection of IgM and IgG against hepatitis E virus in serum and meat juice samples from pigs at slaughter in Bavaria, Germany. Foodborne Pathog Dis 9(7):655\u2013660. https:\/\/doi.org\/10.1089\/fpd.2012.1141","journal-title":"Foodborne Pathog Dis"},{"issue":"24","key":"8622_CR43","doi-asserted-by":"publisher","first-page":"2859","DOI":"10.1016\/j.vaccine.2014.02.025","volume":"32","author":"M Wei","year":"2014","unstructured":"Wei M, Zhang X, Yu H, Tang Z-M, Wang K, Li Z, Zheng Z, Li S, Zhang J, Xia N, Zhao Q (2014) Bacteria expressed hepatitis E virus capsid proteins maintain virion-like epitopes. Vaccine 32(24):2859\u20132865. https:\/\/doi.org\/10.1016\/j.vaccine.2014.02.025","journal-title":"Vaccine"},{"issue":"1","key":"8622_CR44","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.jcv.2011.06.006","volume":"52","author":"JJ Wenzel","year":"2011","unstructured":"Wenzel JJ, Prei\u00df J, Schemmerer M, Huber B, Plentz A, Jilg W (2011) Detection of hepatitis E virus (HEV) from porcine livers in Southeastern Germany and high sequence homology to human HEV isolates. J Clin Virol 52(1):50\u201354. https:\/\/doi.org\/10.1016\/j.jcv.2011.06.006","journal-title":"J Clin Virol"},{"issue":"1","key":"8622_CR45","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1186\/1743-422X-11-90","volume":"11","author":"F Wid\u00e9n","year":"2014","unstructured":"Wid\u00e9n F, Ayral F, Artois M, Olofson A-S, Lin J (2014) PCR detection and analyzis of potentially zoonotic Hepatitis E virus in French rats. Virol J 11(1):90. https:\/\/doi.org\/10.1186\/1743-422X-11-90","journal-title":"Virol J"},{"key":"8622_CR46","volume-title":"Immunofluorescence and related techniques","author":"M Wilson","year":"1978","unstructured":"Wilson M, Nakane P (1978) Recent developments in the periodate method of conjugating horseradish peroxidase (HRPO) to antibodies. In: Knapp W, Holubar K, Wick G (eds) Immunofluorescence and related techniques. Elsevier, Amsterdam"},{"issue":"6","key":"8622_CR47","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.3201\/eid2006.140140","volume":"20","author":"PCY Woo","year":"2014","unstructured":"Woo PCY, Lau SKP, Teng JLL, Tsang AKL, Joseph M, Wong EYM, Tang Y, Sivakumar S, Xie J, Bai R, Wernery R, Wernery U, Yuen K-Y (2014) New hepatitis E virus genotype in camels, the Middle East. Emerg Infect Dis 20(6):1044\u20131048. https:\/\/doi.org\/10.3201\/eid2006.140140","journal-title":"Emerg Infect Dis"},{"issue":"1","key":"8622_CR48","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1006\/viro.1999.0005","volume":"265","author":"L Xing","year":"1999","unstructured":"Xing L, Kato K, Li T, Takeda N, Miyamura T, Hammar L, Cheng RH (1999) Recombinant hepatitis E capsid protein self-assembles into a dual-domain T\u2009=\u20091 particle presenting native virus epitopes. Virology 265(1):35\u201345. https:\/\/doi.org\/10.1006\/viro.1999.0005","journal-title":"Virology"},{"issue":"43","key":"8622_CR49","doi-asserted-by":"publisher","first-page":"33175","DOI":"10.1074\/jbc.M110.106336","volume":"285","author":"L Xing","year":"2010","unstructured":"Xing L, Li T-C, Mayazaki N, Simon MN, Wall JS, Moore M, Wang C-Y, Takeda N, Wakita T, Miyamura T, Cheng RH (2010) Structure of hepatitis E virion-sized particle reveals an RNA-dependent viral assembly pathway. J Biol Chem 285(43):33175\u201333183. https:\/\/doi.org\/10.1074\/jbc.M110.106336","journal-title":"J Biol Chem"},{"issue":"1-2","key":"8622_CR50","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.virusres.2009.02.002","volume":"142","author":"H Zhang","year":"2009","unstructured":"Zhang H, Dai X, Shan X, Meng J (2009) Characterization of antigenic epitopes of the ORF2 protein from hepatitis E virus genotype 4. Virus Res 142(1-2):140\u2013143. https:\/\/doi.org\/10.1016\/j.virusres.2009.02.002","journal-title":"Virus Res"},{"issue":"22","key":"8622_CR51","doi-asserted-by":"publisher","first-page":"2881","DOI":"10.1016\/j.vaccine.2004.11.065","volume":"23","author":"J Zhang","year":"2005","unstructured":"Zhang J, Gu Y, Ge SX, Li SW, He ZQ, Huang GY, Zhuang H, Ng MH, Xia NS (2005) Analysis of hepatitis E virus neutralization sites using monoclonal antibodies directed against a virus capsid protein. Vaccine 23(22):2881\u20132892. https:\/\/doi.org\/10.1016\/j.vaccine.2004.11.065","journal-title":"Vaccine"},{"issue":"20","key":"8622_CR52","doi-asserted-by":"publisher","first-page":"2578","DOI":"10.1016\/j.vaccine.2003.12.017","volume":"22","author":"Y-H Zhou","year":"2004","unstructured":"Zhou Y-H, Purcell RH, Emerson SU (2004) An ELISA for putative neutralizing antibodies to hepatitis E virus detects antibodies to genotypes 1, 2, 3, and 4. Vaccine 22(20):2578\u20132585. https:\/\/doi.org\/10.1016\/j.vaccine.2003.12.017","journal-title":"Vaccine"},{"issue":"1","key":"8622_CR53","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.toxicon.2010.03.007","volume":"56","author":"A Zvirbliene","year":"2010","unstructured":"Zvirbliene A, Pleckaityte M, Lasickiene R, Kucinskaite-Kodze I, Zvirblis G (2010) Production and characterization of monoclonal antibodies against vaginolysin: mapping of a region critical for its cytolytic activity. Toxicon 56(1):19\u201328. https:\/\/doi.org\/10.1016\/j.toxicon.2010.03.007","journal-title":"Toxicon"}],"container-title":["Applied Microbiology and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00253-017-8622-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00253-017-8622-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00253-017-8622-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T21:37:46Z","timestamp":1603316266000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00253-017-8622-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,15]]},"references-count":53,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["8622"],"URL":"https:\/\/doi.org\/10.1007\/s00253-017-8622-9","relation":{},"ISSN":["0175-7598","1432-0614"],"issn-type":[{"value":"0175-7598","type":"print"},{"value":"1432-0614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,15]]}}}