{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T08:52:44Z","timestamp":1791967964391,"version":"4.3.4"},"reference-count":69,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,1,27]],"date-time":"2020-01-27T00:00:00Z","timestamp":1580083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,1,27]],"date-time":"2020-01-27T00:00:00Z","timestamp":1580083200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Microbiol Biotechnol"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1007\/s00253-020-10377-6","type":"journal-article","created":{"date-parts":[[2020,1,27]],"date-time":"2020-01-27T07:02:37Z","timestamp":1580108557000},"page":"2359-2371","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Coleus forskohlii: advancements and prospects of in vitro biotechnology"],"prefix":"10.1007","volume":"104","author":[{"given":"Monisha","family":"Mitra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5059-2428","authenticated-orcid":false,"given":"Saikat","family":"Gantait","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirmal","family":"Mandal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,1,27]]},"reference":[{"key":"10377_CR1","first-page":"3782","volume":"8","author":"PE Akin-Idowu","year":"2009","unstructured":"Akin-Idowu PE, Ibitoye DO, Ademoyegun OT (2009) Tissue culture as a plant production technique for horticultural crops. Afr J Biotechnol 8:3782\u20133788","journal-title":"Afr J Biotechnol"},{"key":"10377_CR2","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1055\/s-0029-1240919","volume":"76","author":"RH Alasbahi","year":"2010","unstructured":"Alasbahi RH, Melzig MF (2010) Plectranthus barbatus: a review of phytochemistry, ethnobotanical uses and pharmacology. Planta Med 76:753\u2013765","journal-title":"Planta Med"},{"key":"10377_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11240-011-0007-7","volume":"108","author":"AO Aremu","year":"2012","unstructured":"Aremu AO, Bairu MW, Dolezal K, Finnie JF, Van Staden J (2012) Topolins: a panacea to plant tissue culture challenges? Plant Cell Tissue Organ Cult 108:1\u201316","journal-title":"Plant Cell Tissue Organ Cult"},{"key":"10377_CR4","unstructured":"Ashwinkumar SK (2006) In: International Conference on Globalization of Traditional, Complementary and Alternative systems of medicine, Tamil Nadu Agricultural University, Coimbatore. pp 29\u201330"},{"key":"10377_CR5","first-page":"2663","volume":"3","author":"P Atulkar","year":"2006","unstructured":"Atulkar P, Thakur R, Singh P (2006) Shoot regeneration from leaf derived callus of Coleus forskohlii Briq. Int J Sci Res 3:2663\u20132664","journal-title":"Int J Sci Res"},{"key":"10377_CR6","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1007\/s11627-011-9417-9","volume":"48","author":"S Balasubramanya","year":"2012","unstructured":"Balasubramanya S, Rajanna L, Anuradha M (2012) Effect of plant growth regulators on morphogenesis and forskolin production in Plectranthus barbatus Andrews. In Vitro Cell Dev Biol-Plant 48:208\u2013215","journal-title":"In Vitro Cell Dev Biol-Plant"},{"key":"10377_CR7","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1097\/00005344-199007000-00013","volume":"16","author":"G Baumann","year":"1990","unstructured":"Baumann G, Felix S, Sattelberger U, Klein G (1990) Cardiovascular effects of forskolin (HL 362) in patients with idiopathic congestive cardiomyopathy - a comparative study with dobutamine and sodium nitroprusside. J Cardiovasc Pharmacol 16:93\u2013100","journal-title":"J Cardiovasc Pharmacol"},{"key":"10377_CR8","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1007\/s11627-001-0100-4","volume":"37","author":"R Bhattacharyya","year":"2001","unstructured":"Bhattacharyya R, Bhattacharya S (2001) In vitro multiplication of Coleus forskohlii Briq: an approach towards shortening the protocol. In Vitro Cell Dev Biol-Plant 37:572\u2013575","journal-title":"In Vitro Cell Dev Biol-Plant"},{"key":"10377_CR9","first-page":"3599","volume":"1","author":"M Bhowal","year":"2017","unstructured":"Bhowal M, Mehta DM (2017) Coleus forskholii: phytochemical and pharmacological profile. Int J Pharm Sci Res 1:3599\u20133618","journal-title":"Int J Pharm Sci Res"},{"key":"10377_CR10","first-page":"74","volume":"40","author":"KPS Chandel","year":"1997","unstructured":"Chandel KPS, Sharma N (1997) Micropropagation of Coleus forskohlii (Willd.) Briq. Biotechnol Agric For 40:74\u201384","journal-title":"Biotechnol Agric For"},{"key":"10377_CR11","first-page":"67","volume":"10","author":"VKS Chandel","year":"1991","unstructured":"Chandel VKS, Sharma N, Srivastav VK (1991) In vitro propagation of Coleus forskohlii Briq. a threatened medicinal plant. Plant Cell Rep 10:67\u201370","journal-title":"Plant Cell Rep"},{"key":"10377_CR12","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1093\/oxfordjournals.aob.a084981","volume":"39","author":"HC Chaturvedi","year":"1975","unstructured":"Chaturvedi HC, Mitra GC (1975) A shift in morphogenetic pattern in Citrus callus tissue during prolonged culture. Ann Bot 39:683\u2013687","journal-title":"Ann Bot"},{"key":"10377_CR13","first-page":"15","volume":"42","author":"AR Chowdhary","year":"1998","unstructured":"Chowdhary AR, Sharma ML (1998) GC-MS investigations on the essential oil from Coleus forskohlii Briq. Indian Perfum 42:15\u201316","journal-title":"Indian Perfum"},{"key":"10377_CR14","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/0147-619X(80)90109-2","volume":"3","author":"A Depicker","year":"1980","unstructured":"Depicker A, De Wilde M, De Vos G, De Vos R, Van Montagu M, Schell J (1980) Molecular cloning of overlapping segments of the nopaline Ti-plasmid pTiC58 as a means to restriction endonuclease mapping. Plasmid 3:193\u2013211","journal-title":"Plasmid"},{"key":"10377_CR15","first-page":"228","volume":"10","author":"P Dube","year":"2011","unstructured":"Dube P, Gangopadhyay M, Dewanjee S, Ali MN (2011) Establishment of a rapid multiplication protocol of Coleus forskohlii Briq and in vitro conservation by reduced growth. Indian J Biotechnol 10:228\u2013231","journal-title":"Indian J Biotechnol"},{"key":"10377_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0378-8741(81)90010-6","volume":"3","author":"MP Dubey","year":"1981","unstructured":"Dubey MP, Srimal RC, Nityanand S, Dhawan BN (1981) Pharmacological studies on coleonol, a hypotensive diterpene from Coleus forskohlii. J Ethnopharmacol 3:1\u201313","journal-title":"J Ethnopharmacol"},{"key":"10377_CR17","volume-title":"Desk reference to nature\u2019s medicine","author":"S Foster","year":"2006","unstructured":"Foster S, Johnson R (2006) Desk reference to nature\u2019s medicine. National Geographic Society, Washington DC"},{"key":"10377_CR18","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.phytol.2016.06.007","volume":"17","author":"M Gangopadhyay","year":"2016","unstructured":"Gangopadhyay M, Gantait S, Palchoudhury S, Ali MN, Mondal C, Pal AK (2016) UVC-priming mediated modulation of forskolin biosynthesis key genes against Macrophomina root rot of Coleus forskohlii - a tissue culture based sustainable approach. Phytochem Lett 17:36\u201344","journal-title":"Phytochem Lett"},{"key":"10377_CR19","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1007\/s11738-017-2462-1","volume":"39","author":"S Gantait","year":"2017","unstructured":"Gantait S, Kundu S (2017a) In vitro biotechnological approaches on Vanilla planifolia Andrews: advancements and opportunities. Acta Physiol Plant 39:196","journal-title":"Acta Physiol Plant"},{"key":"10377_CR20","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1007\/s13205-017-0865-8","volume":"7","author":"S Gantait","year":"2017","unstructured":"Gantait S, Kundu S (2017b) Neoteric trends in tissue culture-mediated biotechnology of Indian ipecac [Tylophora indica (Burm. f.) Merrill]. 3 Biotech 7:231","journal-title":"3 Biotech"},{"key":"10377_CR21","first-page":"18","volume":"3","author":"S Gantait","year":"2009","unstructured":"Gantait S, Mandal N, Bhattacharyya S, Das PK, Nandy S (2009) Mass multiplication of Vanilla planifolia with pure genetic identity confirmed by ISSR. Int J Plant Dev Biol 3:18\u201323","journal-title":"Int J Plant Dev Biol"},{"key":"10377_CR22","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1007\/s11738-015-1847-2","volume":"37","author":"S Gantait","year":"2015","unstructured":"Gantait S, Kundu S, Ali N, Sahu NC (2015) Synthetic seed production of medicinal plants: a review on influence of explants, encapsulation agent and matrix. Acta Physiol Plant 37:98","journal-title":"Acta Physiol Plant"},{"key":"10377_CR23","doi-asserted-by":"publisher","first-page":"8229","DOI":"10.1007\/s00253-018-9232-x","volume":"102","author":"S Gantait","year":"2018","unstructured":"Gantait S, El-Dawayati MM, Panigrahi J, Labrooy C, Verma SK (2018) The retrospect and prospect of the applications of biotechnology in Phoenix dactylifera L. Appl Microbiol Biotechnol 102:8229\u20138259","journal-title":"Appl Microbiol Biotechnol"},{"key":"10377_CR24","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1177\/147323000603400210","volume":"34","author":"R Gonz\u00e1lez-S\u00e1nchez","year":"2006","unstructured":"Gonz\u00e1lez-S\u00e1nchez R, Trujillo X, Trujillo-Hern\u00e1ndez B, V\u00e1squez C, Huerta M, Elizalde A (2006) Forskolin versus sodium cromoglycate for prevention of asthma attacks: a single-blinded clinical trial. J Int Med Res 34:200\u2013207","journal-title":"J Int Med Res"},{"key":"10377_CR25","first-page":"20","volume":"9","author":"C Gopi","year":"2014","unstructured":"Gopi C, Mary MR (2014) In vitro plant regeneration through somatic embryogenesis in medicinally important leaf explants of Coleus forskohlii. Briq J Agric Vet Sci 9:20\u201323","journal-title":"Briq J Agric Vet Sci"},{"key":"10377_CR26","first-page":"77","volume":"3","author":"L Hegde","year":"1991","unstructured":"Hegde L, Krishnan R (1991) Varietal response to chromosomal doubling in Coleus forskohlii briq. Trop Agric Res 3:77\u201389","journal-title":"Trop Agric Res"},{"key":"10377_CR27","first-page":"2167","volume":"4","author":"T Kaul","year":"2015","unstructured":"Kaul T, Malik MA, Yaqoob U, Mehta J (2015) High frequency and rapid in vitro plant regeneration of Coleus forskohlii Briq. Med Arom Plants 4:2167\u20130412","journal-title":"Med Arom Plants"},{"key":"10377_CR28","first-page":"278","volume":"4","author":"C Kavitha","year":"2010","unstructured":"Kavitha C, Rajamani K, Vadivel E (2010) Coleus forskohlii: a comprehensive review on morphology, phytochemistry and pharmacological aspects. J Med Plant Res 4:278\u2013285","journal-title":"J Med Plant Res"},{"key":"10377_CR29","first-page":"4832","volume":"6","author":"BA Khan","year":"2012","unstructured":"Khan BA, Akhtar N, Anwar M, Mahmood T, Khan H, Hussain I, Khan KA (2012) Botanical description of Coleus forskohlii: a review. J Med Plant Res 6:4832\u20134835","journal-title":"J Med Plant Res"},{"key":"10377_CR30","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1007\/s12298-010-0021-y","volume":"16","author":"G Krishna","year":"2010","unstructured":"Krishna G, Reddy PS, Nair NA, Ramteke PW, Bhattacharya PS (2010) In vitro direct shoot regeneration from proximal, middle and distal segment of Coleus forskohlii leaf explants. Physiol Mol Biol Plants 16:195\u2013200","journal-title":"Physiol Mol Biol Plants"},{"key":"10377_CR31","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1007\/s00122-008-0754-y","volume":"117","author":"CW Liu","year":"2008","unstructured":"Liu CW, Lin CC, Yiu JC, Chen JJ, Tseng MJ (2008) Expression of a Bacillus thuringiensis toxin (cry1Ab) gene in cabbage (Brassica oleracea L. var. capitata L.) chloroplasts confers high insecticidal efficacy against Plutella xylostella. Theor Appl Genet 117:75\u201388","journal-title":"Theor Appl Genet"},{"key":"10377_CR32","first-page":"2856","volume":"7","author":"B Lokesh","year":"2018","unstructured":"Lokesh B, Deepa R, Divya K (2018) Medicinal Coleus (Coleus forskohlii Briq): a phytochemical crop of commercial significance. J Pharmacogn Phytochem 7:2856\u20132864","journal-title":"J Pharmacogn Phytochem"},{"key":"10377_CR33","first-page":"153","volume":"8","author":"S Malathy","year":"1999","unstructured":"Malathy S, Pai JS (1999) Monitoring of forskolin production from roots and callus by HPTLC in Coleus forskohlii Briq. J Spices Arom Crop 8:153\u2013157","journal-title":"J Spices Arom Crop"},{"key":"10377_CR34","first-page":"428","volume":"34","author":"S Matsumoto","year":"1990","unstructured":"Matsumoto S, Yamashita T, Araie M, Kametani S, Hosokawa T, Takase M (1990) The ocular penetration of topical forskolin and its effects on intraocular pressure, aqueous flow rate and cyclic AMP level in the rabbit eye. Jpn J Ophthalmol 34:428\u2013435","journal-title":"Jpn J Ophthalmol"},{"key":"10377_CR35","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1055\/s-2006-962403","volume":"54","author":"R Mersinger","year":"1988","unstructured":"Mersinger R, Dornauer H, Reinhard E (1988) Formation of forskolin by suspension cultures of Coleus forskohlii. Planta Med 54:200\u2013204","journal-title":"Planta Med"},{"key":"10377_CR36","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1007\/BF00231926","volume":"15","author":"S Mukherjee","year":"1996","unstructured":"Mukherjee S, Ghosh B, Jha S (1996) Forskolin synthesis in in vitro cultures of Coleus forskohlii Briq transformed with Agrobacterium tumefaciens. Plant Cell Rep 15:691\u2013694","journal-title":"Plant Cell Rep"},{"key":"10377_CR37","doi-asserted-by":"publisher","first-page":"7325","DOI":"10.1007\/s00253-019-10035-6","volume":"103","author":"E Mukherjee","year":"2019","unstructured":"Mukherjee E, Gantait S, Kundu S, Sarkar S, Bhattacharyya S (2019) Biotechnological interventions on the genus Rauvolfia: recent trends and imminent prospects. Appl Microbiol Biotechnol 103:7325\u20137354","journal-title":"Appl Microbiol Biotechnol"},{"key":"10377_CR38","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1111\/j.1399-3054.1962.tb08052.x","volume":"15","author":"T Murashige","year":"1962","unstructured":"Murashige T, Skoog F (1962) A revised medium for rapid growth and bio assays with tobacco tissue cultures. Physiol Plant 15:473\u2013495","journal-title":"Physiol Plant"},{"key":"10377_CR39","first-page":"15","volume":"4","author":"A Nayeem","year":"2014","unstructured":"Nayeem A, Panchakshararadhya RM, Basappa VA (2014) In vitro plant regeneration using adventitious roots as explants in Tylophora indica. Asian J Plant Sci Res 4:15\u201318","journal-title":"Asian J Plant Sci Res"},{"key":"10377_CR40","doi-asserted-by":"publisher","first-page":"58","DOI":"10.3923\/rjmp.2014.1.19","volume":"8","author":"R Pandey","year":"2014","unstructured":"Pandey R, Krishnasamy V, Kumaravadivel N, Rajamani K (2014) Establishment of hairy root culture and production of secondary metabolites in Coleus (Coleus forskohlii). J Med Plant Res 8:58\u201362","journal-title":"J Med Plant Res"},{"key":"10377_CR41","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1007\/s40009-017-0596-8","volume":"40","author":"J Panigrahi","year":"2017","unstructured":"Panigrahi J, Gantait S, Patel IC (2017) An efficient in vitro approach for direct regeneration and callogenesis of Adhatoda vasica Nees, a potential source of quinazoline alkaloids. Natl Acad Sci Lett 40:319\u2013324","journal-title":"Natl Acad Sci Lett"},{"key":"10377_CR42","first-page":"24","volume":"4","author":"PE Rajasekharan","year":"2010","unstructured":"Rajasekharan PE, Ganeshan S, Bhaskaran S (2010) In vitro regeneration and conservation of three Coleus species. Med Aromat Plant Sci Biotechnol 4:24\u201327","journal-title":"Med Aromat Plant Sci Biotechnol"},{"key":"10377_CR43","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1023\/A:1010697813852","volume":"66","author":"PS Reddy","year":"2001","unstructured":"Reddy PS, Rodrigues R, Rajasekharan R (2001) Shoot organogenesis and mass propagation of Coleus forskohlii from leaf derived callus. Plant Cell Tissue Organ Cult 66:183\u2013188","journal-title":"Plant Cell Tissue Organ Cult"},{"key":"10377_CR44","first-page":"1720","volume":"5","author":"CS Reddy","year":"2012","unstructured":"Reddy CS, Praveena C, Veeresham C (2012) Strategies to improve the production of forskolin from hairy root cultures of Coleus forskohlii Briq. Int J Pharm Sci Nanotechnol 5:1720\u20131726","journal-title":"Int J Pharm Sci Nanotechnol"},{"key":"10377_CR45","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1016\/j.biotechadv.2006.05.001","volume":"24","author":"GR Rout","year":"2006","unstructured":"Rout GR, Mohapatra A, Jain S (2006) Tissue culture of ornamental pot plant: a critical review on present scenario and future prospects. Biotechnol Adv 24:531\u2013560","journal-title":"Biotechnol Adv"},{"key":"10377_CR46","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/BF03263344","volume":"19","author":"A Sahai","year":"2010","unstructured":"Sahai A, Shahzad A (2010) In vitro clonal propagation of Coleus forskohlii via direct shoot organogenesis from selected leaf explants. J Plant Biochem Biotechnol 19:223\u2013228","journal-title":"J Plant Biochem Biotechnol"},{"key":"10377_CR47","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1007\/s11738-012-1090-z","volume":"35","author":"A Sahai","year":"2013","unstructured":"Sahai A, Shahzad A (2013) High frequency in vitro regeneration system for conservation of Coleus forskohlii: a threatened medicinal herb. Acta Physiol Plant 35:473\u2013481","journal-title":"Acta Physiol Plant"},{"key":"10377_CR48","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1007\/s002990050425","volume":"17","author":"K Sasaki","year":"1998","unstructured":"Sasaki K, Udagawa A, Ishimaru H, Hayashi T, Alfermann AW, Nakanishi F, Shimomura K (1998) High forskolin production in hairy roots of Coleus forskohlii. Plant Cell Rep 17:457\u2013459","journal-title":"Plant Cell Rep"},{"key":"10377_CR49","doi-asserted-by":"publisher","first-page":"1630","DOI":"10.1104\/pp.108.126003","volume":"148","author":"L Schmidlin","year":"2008","unstructured":"Schmidlin L, Poutaraud A, Claudel P, Mestre P, Prado E, Santos-Rosa M, Wiedemann Merdinoglu S, Karst F, Merdinoglu D, Hugueney P (2008) A stress-inducible resveratrol O-methyltransferase involved in the biosynthesis of pterostilbene in grapevine. Plant Physiol 148:1630\u20131639","journal-title":"Plant Physiol"},{"key":"10377_CR50","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1007\/BF00235360","volume":"9","author":"J Sen","year":"1991","unstructured":"Sen J, Sharma AK (1991) In vitro propagation of Coleus forskohlii Briq. for forskolin synthesis. Plant Cell Rep 9:696\u2013698","journal-title":"Plant Cell Rep"},{"key":"10377_CR51","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1055\/s-2006-961477","volume":"58","author":"J Sen","year":"1992","unstructured":"Sen J, Sharma AK, Sahu NP, Mahato SB (1992) Production of forskolin in in vitro cultures of Coleus forskohlii. Planta Med 58:324\u2013327","journal-title":"Planta Med"},{"key":"10377_CR52","unstructured":"Shah V (1996) Cultivation and utilization of medicinal plants (supplement). RRL and CSIR, Jammu \u2013 Tawai, pp 385\u2013411"},{"key":"10377_CR53","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/BF00236459","volume":"10","author":"N Sharma","year":"1991","unstructured":"Sharma N, Chandel KPS, Srivastava VK (1991) In vitro propagation of Coleus forskohlii Briq. a threatened medicinal plant. Plant Cell Rep 10:67\u201370","journal-title":"Plant Cell Rep"},{"key":"10377_CR54","first-page":"143","volume":"8","author":"E Sreedevi","year":"2014","unstructured":"Sreedevi E, Pullaiah T (2014) Effect of growth regulators on in vitro organogenesis and long term storage of Plectranthus barbatus Andr. (Syn.: Coleus forskohlii (Wild.) Briq.). Curr Trends Biotechnol Pharm 8:143\u2013151","journal-title":"Curr Trends Biotechnol Pharm"},{"key":"10377_CR55","first-page":"2441","volume":"12","author":"E Sreedevi","year":"2013","unstructured":"Sreedevi E, Anuradha M, Pullaiah T (2013a) Plant regeneration from leaf-derived callus in Plectranthus barbatus Andr [Syn.: Coleus forskohlii (Wild.) Briq.]. Afr J Biotechnol 12:2441\u20132448","journal-title":"Afr J Biotechnol"},{"key":"10377_CR56","first-page":"23","volume":"14","author":"E Sreedevi","year":"2013","unstructured":"Sreedevi E, Anuradha M, Pullaiah T (2013b) Relative benefits of using different sugars and coconut water for in vitro regeneration of Plectranthus barbatus [Syn: Coleus forskohlii (Willd.) Briq.]. J Trop Med Plant 14:23\u201329","journal-title":"J Trop Med Plant"},{"key":"10377_CR57","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/BF02708412","volume":"31","author":"M Srinivasan","year":"2006","unstructured":"Srinivasan M, Nachiappan V, Rajasekharan R (2006) Potential application of urea-derived herbicides as cytokinins in plant tissue culture. J Biosci 31:599\u2013605","journal-title":"J Biosci"},{"key":"10377_CR58","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.canlet.2010.10.010","volume":"301","author":"B Sun","year":"2011","unstructured":"Sun B, Geng S, Huang X, Zhu J, Liu S, Zhang Y, Ye J, Li Y, Wang J (2011) Coleusin factor exerts cytotoxic activity by inducing G0\/G1 cell cycle arrest and apoptosis in human gastric cancer BGC-823 cells. Cancer Lett 301:95\u2013105","journal-title":"Cancer Lett"},{"key":"10377_CR59","first-page":"221","volume":"57","author":"G Swaroopa","year":"2007","unstructured":"Swaroopa G, Nigam N, Maniyam A (2007) Germplasm conservation of selected lines of Coleus forskohlii (Willd.) Briq. by nodal segment encapsulation. Phytomorphol 57:221\u2013225","journal-title":"Phytomorphol"},{"key":"10377_CR60","first-page":"755","volume":"7","author":"G Swaroopa","year":"2013","unstructured":"Swaroopa G, Anuradha M, Pullaiah T (2013a) Elicitation of forskolin in suspension cultures of Coleus forskohlii (wild) Briq using elicitors of fungal origin. Curr Trends Biotechnol Pharm 7:755\u2013762","journal-title":"Curr Trends Biotechnol Pharm"},{"key":"10377_CR61","first-page":"97","volume":"92","author":"G Swaroopa","year":"2013","unstructured":"Swaroopa G, Anuradha M, Pullaiah T (2013b) Elicitation of Forskolin in suspension cultures of Coleus forskohlii (Willd.) Briq. using bacterial elicitors. J Indian Bot Soc 92:97\u2013100","journal-title":"J Indian Bot Soc"},{"key":"10377_CR62","first-page":"81","volume":"15","author":"G Swaroopa","year":"2015","unstructured":"Swaroopa G, Anuradha M, Pullaiah T (2015) Elicitation of Forskolin in suspension cultures of Coleus forskolii (Willd.) Briq. using abiotic elicitors. J Trop Med Plant 15:81\u201386","journal-title":"J Trop Med Plant"},{"key":"10377_CR63","first-page":"45","volume":"10","author":"G Swaroopa","year":"2016","unstructured":"Swaroopa G, Anuradha M, Pullaiah T (2016) Influence of sucrose and plant growth regulators on growth and forskolin production in callus cultures of Coleus forskohlii. Curr Trend Biotechnol Pharm 10:45\u201354","journal-title":"Curr Trend Biotechnol Pharm"},{"key":"10377_CR64","doi-asserted-by":"publisher","first-page":"41","DOI":"10.3923\/ijb.2005.41.49","volume":"1","author":"JA Teixeira da Silva","year":"2005","unstructured":"Teixeira da Silva JA, Giang DDT, Tanaka M (2005) In vitro acclimatization of banana and Cymbidium. Int J Bot 1:41\u201349","journal-title":"Int J Bot"},{"key":"10377_CR65","first-page":"126","volume":"19","author":"P Thangavel","year":"2014","unstructured":"Thangavel P, Prabhu S, Britto SJ (2014) High frequency shoots regeneration from nodal explants of Plectranthus barbatus Andrews belong to the Lamiaceae. J Andaman Sci Assoc 19:126\u2013135","journal-title":"J Andaman Sci Assoc"},{"key":"10377_CR66","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1007\/BF00130801","volume":"17","author":"CKM Tripathi","year":"1995","unstructured":"Tripathi CKM, Basu SK, Jain S, Tandon JS (1995) Production of coleonol (forskolin) by root callus cells of plant Coleus forskohlii. Biotechnol Lett 17:423\u2013426","journal-title":"Biotechnol Lett"},{"key":"10377_CR67","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1007\/BF02908139","volume":"44","author":"LJ Valdes","year":"1987","unstructured":"Valdes LJ, Mislankar SG, Paul AG (1987) Coleus barbatus (C. forskohlii) (Lamiaceae) and the potential new drug forskolin (coleonol). Econ Bot 44:474\u2013483","journal-title":"Econ Bot"},{"key":"10377_CR68","first-page":"574","volume":"5","author":"RK Vibhuti","year":"2019","unstructured":"Vibhuti RK, Kumar D (2019) Effect of 6-BAP on callus culture and shoot multiplication of Coleus forskohlii (syn Plectranthus forskohlli wild) briq. Res J Life Sci Bioinform Chem Sci 5:574\u2013581","journal-title":"Res J Life Sci Bioinform Chem Sci"},{"key":"10377_CR69","first-page":"112","volume":"3","author":"N Vijaya Sree","year":"2010","unstructured":"Vijaya Sree N, Udayasri P, Aswani kumar VVY, Ravi BB, Phani KY, Vijay VM (2010) Advancements in the production of secondary metabolites. J Nat Prod 3:112\u2013123","journal-title":"J Nat Prod"}],"container-title":["Applied Microbiology and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00253-020-10377-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00253-020-10377-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00253-020-10377-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,16]],"date-time":"2022-04-16T15:05:10Z","timestamp":1650121510000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00253-020-10377-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,27]]},"references-count":69,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10377"],"URL":"https:\/\/doi.org\/10.1007\/s00253-020-10377-6","relation":{},"ISSN":["0175-7598","1432-0614"],"issn-type":[{"value":"0175-7598","type":"print"},{"value":"1432-0614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,27]]},"assertion":[{"value":"8 December 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 December 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 January 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 January 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}