{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:08:24Z","timestamp":1792782504108,"version":"4.5.0"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"15","license":[{"start":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T00:00:00Z","timestamp":1591920000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T00:00:00Z","timestamp":1591920000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31801583"],"award-info":[{"award-number":["31801583"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31922073"],"award-info":[{"award-number":["31922073"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20180607"],"award-info":[{"award-number":["BK20180607"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National First-Class Discipline Program of Food Science and Technology of China","award":["JUFSTR20180203"],"award-info":[{"award-number":["JUFSTR20180203"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Microbiol Biotechnol"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1007\/s00253-020-10735-4","type":"journal-article","created":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T02:02:46Z","timestamp":1591927366000},"page":"6429-6441","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Ribose-5-phosphate isomerases: characteristics, structural features, and applications"],"prefix":"10.1007","volume":"104","author":[{"given":"Jiajun","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7861-0170","authenticated-orcid":false,"given":"Wenli","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanmeng","family":"Mu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,6,12]]},"reference":[{"issue":"4","key":"10735_CR1","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1002\/cbic.201402620","volume":"16","author":"A Bosshart","year":"2015","unstructured":"Bosshart A, Hee CS, Bechtold M, Schirmer T, Panke S (2015) Directed divergent evolution of a thermostable D-tagatose epimerase towards improved activity for two hexose substrates. ChemBioChem 16(4):592\u2013601. https:\/\/doi.org\/10.1002\/cbic.201402620","journal-title":"ChemBioChem"},{"key":"10735_CR2","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.jmgm.2014.11.002","volume":"55","author":"P Capriles","year":"2015","unstructured":"Capriles P, Baprista LPR, Guedes IA, Guimaraes ACR, Custodio FL, Alves-Ferreira M, Dardenne LE (2015) Structural modeling and docking studies of ribose 5-phosphate isomerase from Leishmania major and Homo sapiens: a comparative analysis for Leishmaniasis treatment. J Mol Graph 55:134\u2013147. https:\/\/doi.org\/10.1016\/j.jmgm.2014.11.002","journal-title":"J Mol Graph"},{"issue":"45","key":"10735_CR3","doi-asserted-by":"publisher","first-page":"12017","DOI":"10.1021\/acs.jafc.8b05107","volume":"66","author":"ZW Chen","year":"2018","unstructured":"Chen ZW, Chen JJ, Zhang WL, Zhang T, Guang C, Mu WM (2018a) Improving thermostability and catalytic behavior of L-rhamnose isomerase from Caldicellulosiruptor obsidiansis OB47 toward D-allulose by site-directed mutagenesis. J Agric Food Chem 66(45):12017\u201312024. https:\/\/doi.org\/10.1021\/acs.jafc.8b05107","journal-title":"J Agric Food Chem"},{"issue":"10","key":"10735_CR4","doi-asserted-by":"publisher","first-page":"4269","DOI":"10.1007\/s00253-018-8916-6","volume":"102","author":"ZW Chen","year":"2018","unstructured":"Chen ZW, Chen JJ, Zhang WL, Zhang T, Guang C, Mu WM (2018b) Recent research on the physiological functions, applications, and biotechnological production of D-allose. Appl Microbiol Biotechnol 102(10):4269\u20134278. https:\/\/doi.org\/10.1007\/s00253-018-8916-6","journal-title":"Appl Microbiol Biotechnol"},{"issue":"6","key":"10735_CR5","doi-asserted-by":"publisher","first-page":"2184","DOI":"10.1002\/jsfa.8703","volume":"98","author":"ZW Chen","year":"2018","unstructured":"Chen ZW, Xu W, Zhang WL, Zhang T, Jiang B, Mu WM (2018c) Characterization of a thermostable recombinant L-rhamnose isomerase from Caldicellulosiruptor obsidiansis OB47 and its application for the production of L-fructose and L-rhamnulose. J Sci Food Agric 98(6):2184\u20132193. https:\/\/doi.org\/10.1002\/jsfa.8703","journal-title":"J Sci Food Agric"},{"issue":"1","key":"10735_CR6","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1002\/ijc.29361","volume":"137","author":"SC Ciou","year":"2015","unstructured":"Ciou SC, Chou YT, Liu YL, Nieh YC, Lu JW, Huang SF, Chou YT, Cheng LH, Lo JF, Chen MJ, Yang MC, Yuh CH, Wang HD (2015) Ribose-5-phosphate isomerase a regulates hepatocarcinogenesis via PP2A and ERK signaling. Int J Cancer 137(1):104\u2013115. https:\/\/doi.org\/10.1002\/ijc.29361","journal-title":"Int J Cancer"},{"issue":"1","key":"10735_CR7","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/1472-6807-11-39","volume":"11","author":"TE Edwards","year":"2011","unstructured":"Edwards TE, Abramov AB, Smith ER, Baydo RO, Leonard JT, Leibly DJ, Thompkins KB, Clifton MC, Gardberg AS, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ (2011) Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. BMC Struct Biol 11(1):39\u201347. https:\/\/doi.org\/10.1186\/1472-6807-11-39","journal-title":"BMC Struct Biol"},{"issue":"7","key":"10735_CR8","doi-asserted-by":"publisher","first-page":"1480","DOI":"10.1007\/s12010-015-1828-3","volume":"177","author":"C Fan","year":"2015","unstructured":"Fan C, Xu W, Zhang T, Zhou L, Jiang B, Mu WM (2015) Engineering of Alicyclobacillus hesperidum L-arabinose isomerase for improved catalytic activity and reduced pH optimum using random and site-directed mutagenesis. Appl Biochem Biotechnol 177(7):1480\u20131492. https:\/\/doi.org\/10.1007\/s12010-015-1828-3","journal-title":"Appl Biochem Biotechnol"},{"key":"10735_CR9","doi-asserted-by":"publisher","first-page":"26937","DOI":"10.1038\/srep26937","volume":"6","author":"J Faria","year":"2016","unstructured":"Faria J, Loureiro I, Santarem N, Cecilio P, Macedo-Ribeiro S, Tavares J, Cordeiro-Da-Silva A (2016) Disclosing the essentiality of ribose-5-phosphate isomerase B in trypanosomatids. Sci Rep 6:26937\u201323952. https:\/\/doi.org\/10.1038\/srep26937","journal-title":"Sci Rep"},{"issue":"5","key":"10735_CR10","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1007\/s10529-013-1136-3","volume":"35","author":"Z Feng","year":"2013","unstructured":"Feng Z, Mu W, Jiang B (2013) Characterization of ribose-5-phosphate isomerase converting D-psicose to D-allose from Thermotoga lettingae TMO. Biotechnol Lett 35(5):719\u2013724. https:\/\/doi.org\/10.1007\/s10529-013-1136-3","journal-title":"Biotechnol Lett"},{"issue":"21","key":"10735_CR11","doi-asserted-by":"publisher","first-page":"6464","DOI":"10.1021\/bi049812o","volume":"43","author":"TD Fenn","year":"2004","unstructured":"Fenn TD, Ringe D, Petsko GA (2004) Xylose isomerase in substrate and inhibitor Michaelis states: atomic resolution studies of a metal-mediated hydride shift. Biochemistry 43(21):6464\u20136474. https:\/\/doi.org\/10.1021\/bi049812o","journal-title":"Biochemistry"},{"issue":"8","key":"10735_CR12","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.biochi.2005.03.001","volume":"87","author":"M Graille","year":"2005","unstructured":"Graille M, Meyer P, Leulliot N, Sorel I, Janin J, Van Tilbeurgh H, Quevillon-Cheruel S (2005) Crystal structure of the S. cerevisiae D-ribose-5-phosphate isomerase: comparison with the archaeal and bacterial enzymes. Biochimie 87(8):763\u2013769. https:\/\/doi.org\/10.1016\/j.biochi.2005.03.001","journal-title":"Biochimie"},{"issue":"2","key":"10735_CR13","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/s1389-1723(04)70173-5","volume":"97","author":"TB Granstrom","year":"2004","unstructured":"Granstrom TB, Takata G, Tokuda M, Izumori K (2004) Izumoring: a novel and complete strategy for bioproduction of rare sugars. J Biosci Bioeng 97(2):89\u201394. https:\/\/doi.org\/10.1016\/s1389-1723(04)70173-5","journal-title":"J Biosci Bioeng"},{"issue":"49","key":"10735_CR14","doi-asserted-by":"publisher","first-page":"49183","DOI":"10.1074\/jbc.M309272200","volume":"278","author":"K Hamada","year":"2003","unstructured":"Hamada K, Ago H, Sugahara M, Nodake Y, Kuramitsu S, Miyano M (2003) Oxyanion hole-stabilized stereospecific isomerization in ribose-5-phosphate isomerase (Rpi). J Biol Chem 278(49):49183\u201349190. https:\/\/doi.org\/10.1074\/jbc.M309272200","journal-title":"J Biol Chem"},{"issue":"24","key":"10735_CR15","doi-asserted-by":"publisher","first-page":"8223","DOI":"10.1016\/0040-4020(96)00379-1","volume":"52","author":"L Hecquet","year":"1996","unstructured":"Hecquet L, Bolte J, Demuynck C (1996) Enzymatic synthesis of \u201cnatural-labeled\u201d 6-deoxy-L-sorbose precursor of an important food flavor. Tetrahedron 52(24):8223\u20138232. https:\/\/doi.org\/10.1016\/0040-4020(96)00379-1","journal-title":"Tetrahedron"},{"issue":"10","key":"10735_CR16","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1016\/j.chembiol.2005.08.016","volume":"12","author":"C Hofmann","year":"2005","unstructured":"Hofmann C, Boll R, Heitmann B, Hauser G, Durr C, Frerich A, Weitnauer G, Glaser SJ, Bechthold A (2005) Genes encoding enzymes responsible for biosynthesis of L-lyxose and attachment of eurekanate during avilamycin biosynthesis. Chem Biol 12(10):1137\u20131143. https:\/\/doi.org\/10.1016\/j.chembiol.2005.08.016","journal-title":"Chem Biol"},{"issue":"5","key":"10735_CR17","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1107\/s1744309106010876","volume":"62","author":"MA Holmes","year":"2006","unstructured":"Holmes MA, Buckner FS, Van Voorhis WC, Verlinde C, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Earnest TN, Hol WGJ, Merritt EA (2006) Structure of ribose 5-phosphate isomerase from Plasmodium falciparum. Acta Crystallogr F-Struct Biol Commun 62(5):427\u2013431. https:\/\/doi.org\/10.1107\/s1744309106010876","journal-title":"Acta Crystallogr F-Struct Biol Commun"},{"issue":"4","key":"10735_CR18","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1086\/383204","volume":"74","author":"JHJ Huck","year":"2004","unstructured":"Huck JHJ, Verhoeven NM, Struys EA, Salomons GS, Jakobs C, van der Knaap MS (2004) Ribose-5-phosphate isomerase deficiency: new inborn error in the pentose phosphate pathway associated with a slowly progressive leukoencephalopathy. Am J Hum Genet 74(4):745\u2013751. https:\/\/doi.org\/10.1086\/383204","journal-title":"Am J Hum Genet"},{"issue":"6","key":"10735_CR19","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1016\/s0969-2126(02)00779-7","volume":"10","author":"K Ishikawa","year":"2002","unstructured":"Ishikawa K, Matsui I, Payan F, Cambillau C, Ishida H, Kawarabayasi Y, Kikuchi H, Roussel A (2002) A hyperthermostable D-ribose-5-phosphate isomerase from Pyrococcus horikoshii characterization and three-dimensional structure. Structure 10(6):877\u2013886. https:\/\/doi.org\/10.1016\/s0969-2126(02)00779-7","journal-title":"Structure"},{"issue":"3","key":"10735_CR20","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1007\/s00114-002-0297-z","volume":"89","author":"K Izumori","year":"2002","unstructured":"Izumori K (2002) Bioproduction strategies for rare hexose sugars. Naturwissenschaften 89(3):120\u2013124. https:\/\/doi.org\/10.1007\/s00114-002-0297-z","journal-title":"Naturwissenschaften"},{"issue":"15","key":"10735_CR21","doi-asserted-by":"publisher","first-page":"4064","DOI":"10.1021\/ol201552q","volume":"13","author":"SF Jenkinson","year":"2011","unstructured":"Jenkinson SF, Fleet GWJ, Nash RJ, Koike Y, Adachi I, Yoshihara A, Morimoto K, Izumori K, Kato A (2011) Looking-glass synergistic pharmacological chaperones: DGJ and L-DGJ from the enantiomers of tagatose. Org Lett 13(15):4064\u20134067. https:\/\/doi.org\/10.1021\/ol201552q","journal-title":"Org Lett"},{"issue":"2","key":"10735_CR22","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1006\/abbi.1999.1554","volume":"373","author":"CH Jung","year":"2000","unstructured":"Jung CH, Hartman FC, Lu TYS, Larimer FW (2000) D-ribose-5-phosphate isomerase from spinach: heterologous overexpression, purification, characterization, and site-directed mutagenesis of the recombinant enzyme. Arch Biochem Biophys 373(2):409\u2013417. https:\/\/doi.org\/10.1006\/abbi.1999.1554","journal-title":"Arch Biochem Biophys"},{"issue":"2","key":"10735_CR23","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1007\/s00253-011-3095-8","volume":"90","author":"J Jung","year":"2011","unstructured":"Jung J, Kim JK, Yeom SJ, Ahn YJ, Oh DK, Kang LW (2011) Crystal structure of Clostridium thermocellum ribose-5-phosphate isomerase B reveals properties critical for fast enzyme kinetics. Appl Microbiol Biotechnol 90(2):517\u2013527. https:\/\/doi.org\/10.1007\/s00253-011-3095-8","journal-title":"Appl Microbiol Biotechnol"},{"issue":"3","key":"10735_CR24","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/j.bbrc.2004.05.045","volume":"319","author":"Y Kakuta","year":"2004","unstructured":"Kakuta Y, Tahara M, Maetani S, Yao M, Tanaka I, Kimura M (2004) Crystal structure of the regulatory subunit of archaeal initiation factor 2B (aIF2B) from hyperthermophilic archaeon Pyrococcus horikoshii OT3: a proposed structure of the regulatory subcomplex of eukaryotic IF2B. Biochem Biophys Res Commun 319(3):725\u2013732. https:\/\/doi.org\/10.1016\/j.bbrc.2004.05.045","journal-title":"Biochem Biophys Res Commun"},{"issue":"8","key":"10735_CR25","doi-asserted-by":"publisher","first-page":"103708","DOI":"10.1016\/j.ejmg.2019.103708","volume":"62","author":"P Kaur","year":"2019","unstructured":"Kaur P, Wamelink MMC, van der Knaap MS, Girisha KM, Shukla A (2019) Confirmation of a rare genetic leukoencephalopathy due to a novel biallelic variant in RPIA. Eur J Med Genet 62(8):103708\u2013103711. https:\/\/doi.org\/10.1016\/j.ejmg.2019.103708","journal-title":"Eur J Med Genet"},{"issue":"1","key":"10735_CR26","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s10059-009-0010-6","volume":"27","author":"TG Kim","year":"2009","unstructured":"Kim TG, Kwon TH, Min K, Dong MS, Park YI, Ban C (2009) Crystal structures of substrate and inhibitor complexes of ribose 5-phosphate isomerase a from Vibrio vulnificus YJ016. Mol Cells 27(1):99\u2013103. https:\/\/doi.org\/10.1007\/s10059-009-0010-6","journal-title":"Mol Cells"},{"issue":"4","key":"10735_CR27","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1006\/jmbi.2000.3896","volume":"300","author":"IP Korndorfer","year":"2000","unstructured":"Korndorfer IP, Fessner WD, Matthews BW (2000) The structure of rhamnose isomerase from Escherichia coli and its relation with xylose isomerase illustrates a change between inter and intra-subunit complementation during evolution. J Mol Biol 300(4):917\u2013933. https:\/\/doi.org\/10.1006\/jmbi.2000.3896","journal-title":"J Mol Biol"},{"issue":"8","key":"10735_CR28","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1016\/j.pt.2016.04.010","volume":"32","author":"J Kovarova","year":"2016","unstructured":"Kovarova J, Barrett MP (2016) The pentose phosphate pathway in parasitic trypanosomatids. Trends Parasitol 32(8):622\u2013634. https:\/\/doi.org\/10.1016\/j.pt.2016.04.010","journal-title":"Trends Parasitol"},{"issue":"3","key":"10735_CR29","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1007\/s10068-014-0092-6","volume":"23","author":"SY Kwon","year":"2014","unstructured":"Kwon SY, Baek HH (2014) Effects of temperature, pH, organic acids, and sulfites on tagatose browning in solutions during processing and storage. Food Sci Biotechnol 23(3):677\u2013684. https:\/\/doi.org\/10.1007\/s10068-014-0092-6","journal-title":"Food Sci Biotechnol"},{"issue":"3","key":"10735_CR30","doi-asserted-by":"publisher","first-page":"418","DOI":"10.4014\/jmb.1709.09044","volume":"28","author":"TE Lee","year":"2018","unstructured":"Lee TE, Shin KC, Oh DK (2018) Biotransformation of fructose to allose by a one-pot reaction using Flavonifractor plautii D-allulose 3-epimerase and Clostridium thermocellum ribose 5-phosphate isomerase. J Microbiol Biotechnol 28(3):418\u2013424. https:\/\/doi.org\/10.4014\/jmb.1709.09044","journal-title":"J Microbiol Biotechnol"},{"issue":"12","key":"10735_CR31","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1107\/s174430911204273x","volume":"68","author":"CMC Lobley","year":"2012","unstructured":"Lobley CMC, Aller P, Douangamath A, Reddivari Y, Bumann M, Bird LE, Nettleship JE, Brandao-Neto J, Owens RJ, O'Toole PW, Walsh MA (2012) Structure of ribose 5-phosphate isomerase from the probiotic bacterium Lactobacillus salivarius UCC118. Acta Crystallogr F-Struct Biol Commun 68(12):1427\u20131433. https:\/\/doi.org\/10.1107\/s174430911204273x","journal-title":"Acta Crystallogr F-Struct Biol Commun"},{"issue":"1","key":"10735_CR32","doi-asserted-by":"publisher","first-page":"e3430","DOI":"10.1371\/journal.pntd.0003430","volume":"9","author":"I Loureiro","year":"2015","unstructured":"Loureiro I, Faria J, Clayton C, Macedo-Ribeiro S, Santarem N, Roy N, Cordeiro-Da-Siva A, Tavares J (2015) Ribose 5-phosphate isomerase B knockdown compromises Trypanosoma brucei bloodstream form infectivity. Plos Neglect Trop Dis 9(1):e3430\u2013e3440. https:\/\/doi.org\/10.1371\/journal.pntd.0003430","journal-title":"Plos Neglect Trop Dis"},{"issue":"6","key":"10735_CR33","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1016\/j.enzmictec.2005.08.014","volume":"38","author":"K Morimoto","year":"2006","unstructured":"Morimoto K, Park CS, Ozaki M, Takeshita K, Shimonishi T, Granstrom TB, Takata G, Tokuda M, Izumori K (2006) Large scale production of D-allose from D-psicose using continuous bioreactor and separation system. Enzym Microb Technol 38(6):855\u2013859. https:\/\/doi.org\/10.1016\/j.enzmictec.2005.08.014","journal-title":"Enzym Microb Technol"},{"issue":"9","key":"10735_CR34","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1007\/s10529-007-9393-7","volume":"29","author":"CS Park","year":"2007","unstructured":"Park CS, Yeom SJ, Kim HJ, Lee SH, Lee JK, Kim SW, Oh DK (2007a) Characterization of ribose-5-phosphate isomerase of Clostridium thermocellum producing D-allose from D-psicose. Biotechnol Lett 29(9):1387\u20131391. https:\/\/doi.org\/10.1007\/s10529-007-9393-7","journal-title":"Biotechnol Lett"},{"issue":"1","key":"10735_CR35","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.jbiotec.2007.08.022","volume":"132","author":"HY Park","year":"2007","unstructured":"Park HY, Park CS, Kim HJ, Oh DK (2007b) Substrate specificity of a galactose 6-phosphate isomerase from Lactococcus lactis that produces D-allose from D-psicose. J Biotechnol 132(1):88\u201395. https:\/\/doi.org\/10.1016\/j.jbiotec.2007.08.022","journal-title":"J Biotechnol"},{"issue":"4","key":"10735_CR36","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1007\/s11274-010-0511-7","volume":"27","author":"CS Park","year":"2011","unstructured":"Park CS, Yeom SJ, Lim YR, Kim YS, Oh DK (2011) Substrate specificity of a recombinant ribose-5-phosphate isomerase from Streptococcus pneumoniae and its application in the production of L-lyxose and L-tagatose. World J Microbiol Biotechnol 27(4):743\u2013750. https:\/\/doi.org\/10.1007\/s11274-010-0511-7","journal-title":"World J Microbiol Biotechnol"},{"issue":"22","key":"10735_CR37","doi-asserted-by":"publisher","first-page":"7126","DOI":"10.1128\/jb.181.22.7126-7130.1999","volume":"181","author":"TS Poulsen","year":"1999","unstructured":"Poulsen TS, Chang YY, Hove-Jensen B (1999) D-Allose catabolism of Escherichia coli: involvement of alsI and regulation of als regulon expression by allose and ribose. J Bacteriol 181(22):7126\u20137130. https:\/\/doi.org\/10.1128\/jb.181.22.7126-7130.1999","journal-title":"J Bacteriol"},{"issue":"4","key":"10735_CR38","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1002\/prot.10203","volume":"48","author":"ES Rangarajan","year":"2002","unstructured":"Rangarajan ES, Sivaraman J, Matte A, Cygler M (2002) Crystal structure of D-ribose-5-phosphate isomerase (RpiA) from Escherichia coli. Proteins 48(4):737\u2013740. https:\/\/doi.org\/10.1002\/prot.10203","journal-title":"Proteins"},{"issue":"3","key":"10735_CR39","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1016\/j.jmb.2003.11.021","volume":"335","author":"AK Roos","year":"2004","unstructured":"Roos AK, Andersson CE, Bergfors T, Jacobsson M, Karlen A, Unge T, Jones TA, Mowbray SL (2004) Mycobacterium tuberculosis ribose-5-phosphate isomerase has a known fold, but a novel active site. J Mol Biol 335(3):799\u2013809. https:\/\/doi.org\/10.1016\/j.jmb.2003.11.021","journal-title":"J Mol Biol"},{"issue":"8","key":"10735_CR40","doi-asserted-by":"publisher","first-page":"6416","DOI":"10.1074\/jbc.M412018200","volume":"280","author":"AK Roos","year":"2005","unstructured":"Roos AK, Burgos E, Ericsson DJ, Salmon L, Mowbray SL (2005) Competitive inhibitors of Mycobacterium tuberculosis ribose-5-phosphate isomerase B reveal new information about the reaction mechanism. J Biol Chem 280(8):6416\u20136422. https:\/\/doi.org\/10.1074\/jbc.M412018200","journal-title":"J Biol Chem"},{"issue":"3","key":"10735_CR41","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1016\/j.jmb.2008.06.090","volume":"382","author":"AK Roos","year":"2008","unstructured":"Roos AK, Mariano S, Kowalinski E, Salmon L, Mowbray SL (2008) D-Ribose-5-phosphate isomerase B from Escherichia coli is also a functional D-allose-6-phosphate isomerase, while the Mycobacterium tuberculosis enzyme is not. J Mol Biol 382(3):667\u2013679. https:\/\/doi.org\/10.1016\/j.jmb.2008.06.090","journal-title":"J Mol Biol"},{"issue":"7","key":"10735_CR42","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.4014\/jmb.1802.02021","volume":"28","author":"M Shen","year":"2018","unstructured":"Shen M, Ju X, Xu XQ, Yao X, Li L, Chen J, Hu C, Fu J, Yan L (2018) Characterization of ribose-5-phosphate isomerase B from newly isolated strain Ochrobactrum sp CSL1 producing L-rhamnulose from L-rhamnose. J Microbiol Biotechnol 28(7):1122\u20131132. https:\/\/doi.org\/10.4014\/jmb.1802.02021","journal-title":"J Microbiol Biotechnol"},{"key":"10735_CR43","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.jmgm.2017.08.007","volume":"77","author":"VDC Sinatti","year":"2017","unstructured":"Sinatti VDC, Baptista LPR, Alves-Ferreira M, Dardenne L, da Silva JHM, Guimaraes AC (2017) In silico identification of inhibitors of ribose 5-phosphate isomerase from Trypanosoma cruzi using ligand and structure based approaches. J Mol Graph 77:168\u2013180. https:\/\/doi.org\/10.1016\/j.jmgm.2017.08.007","journal-title":"J Mol Graph"},{"key":"10735_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/07391102.2019.1626769","volume":"38","author":"RF Soares","year":"2019","unstructured":"Soares RF, Antunes D, Santos LHS, Rocha GV, Bastos LS, Guimaraes ACR, Caffarena ER (2019) Studying effects of different protonation states of His11 and His102 in ribose-5-phosphate isomerase of Trypanosoma cruzi: an example of cooperative behavior. J Biomol Struct Dyn 38:1\u201310. https:\/\/doi.org\/10.1080\/07391102.2019.1626769","journal-title":"J Biomol Struct Dyn"},{"issue":"1","key":"10735_CR45","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1042\/bj20061049","volume":"401","author":"AL Stern","year":"2007","unstructured":"Stern AL, Burgos E, Salmon L, Cazzulo JJ (2007) Ribose 5-phosphate isomerase type B from Trypanosoma cruzi: kinetic properties and site-directed mutagenesis reveal information about the reaction mechanism. Biochem J 401(1):279\u2013285. https:\/\/doi.org\/10.1042\/bj20061049","journal-title":"Biochem J"},{"issue":"5","key":"10735_CR46","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1111\/j.1742-4658.2010.07999.x","volume":"278","author":"AL Stern","year":"2011","unstructured":"Stern AL, Naworyta A, Cazzulo JJ, Mowbray SL (2011) Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family. FEBS J 278(5):793\u2013808. https:\/\/doi.org\/10.1111\/j.1742-4658.2010.07999.x","journal-title":"FEBS J"},{"issue":"3","key":"10735_CR47","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1111\/brv.12140","volume":"90","author":"A Stincone","year":"2015","unstructured":"Stincone A, Prigione A, Cramer T, Wamelink MMC, Campbell K, Cheung E, Olin-Sandoval V, Gruning NM, Kruger A, Alam MT, Keller MA, Breitenbach M, Brindle KM, Rabinowitz JD, Ralser M (2015) The return of metabolism: biochemistry and physiology of the pentose phosphate pathway. Biol Rev 90(3):927\u2013963. https:\/\/doi.org\/10.1111\/brv.12140","journal-title":"Biol Rev"},{"issue":"12","key":"10735_CR48","doi-asserted-by":"publisher","first-page":"1214","DOI":"10.1107\/s1744309109044923","volume":"65","author":"RW Strange","year":"2009","unstructured":"Strange RW, Antonyuk SV, Ellis MJ, Bessho Y, Kuramitsu S, Yokoyama S, Hasnain SS (2009) The structure of an archaeal ribose-5-phosphate isomerase from Methanocaldococcus jannaschii (MJ1603). Acta Crystallogr F-Struct Biol Commun 65(12):1214\u20131217. https:\/\/doi.org\/10.1107\/s1744309109044923","journal-title":"Acta Crystallogr F-Struct Biol Commun"},{"issue":"14","key":"10735_CR49","doi-asserted-by":"publisher","first-page":"4182","DOI":"10.1002\/anie.201411279","volume":"54","author":"N Wagner","year":"2015","unstructured":"Wagner N, Bosshart A, Failmezger J, Bechtold M, Panke S (2015) A separation-integrated cascade reaction to overcome thermodynamic limitations in rare-sugar synthesis. Angew Chem-Int Edit 54(14):4182\u20134186. https:\/\/doi.org\/10.1002\/anie.201411279","journal-title":"Angew Chem-Int Edit"},{"issue":"32","key":"10735_CR50","doi-asserted-by":"publisher","first-page":"9354","DOI":"10.1021\/jp404948c","volume":"117","author":"J Wang","year":"2013","unstructured":"Wang J, Yang W (2013) Concerted proton transfer mechanism of Clostridium thermocellum ribose-5-phosphate isomerase. J Phys Chem B 117(32):9354\u20139361. https:\/\/doi.org\/10.1021\/jp404948c","journal-title":"J Phys Chem B"},{"issue":"1","key":"10735_CR51","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1002\/prot.20129","volume":"56","author":"Q Xu","year":"2004","unstructured":"Xu Q, Schwarzenbacher R, McMullan D, von Delft F, Brinen LS, Canaves JM, Dai XP, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, Lesley SA, Levin I, TM MP, Miller MD, Morse A, Moy K, Ouyang J, Page R, Quijano K, Robb A, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, Wang XH, West B, Wolf G, Hodgson KO, Wooley J, Wilson IA (2004) Crystal structure of a ribose-5-phosphate isomerase RpiB (TM1080) from Thermotoga maritima at 1.90 angstrom resolution. Proteins 56(1):171\u2013175. https:\/\/doi.org\/10.1002\/prot.20129","journal-title":"Proteins"},{"issue":"7","key":"10735_CR52","doi-asserted-by":"publisher","first-page":"2985","DOI":"10.1007\/s00253-016-7369-z","volume":"100","author":"W Xu","year":"2016","unstructured":"Xu W, Zhang W, Zhang T, Jiang B, Mu W (2016) L-Rhamnose isomerase and its use for biotechnological production of rare sugars. Appl Microbiol Biotechnol 100(7):2985\u20132992. https:\/\/doi.org\/10.1007\/s00253-016-7369-z","journal-title":"Appl Microbiol Biotechnol"},{"key":"10735_CR53","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.procbio.2016.11.025","volume":"53","author":"W Xu","year":"2017","unstructured":"Xu W, Zhang W, Tian Y, Zhang T, Jiang B, Mu W (2017) Characterization of a novel thermostable L-rhamnose isomerase from Thermobacillus composti KWC4 and its application for production of D-allose. Process Biochem 53:153\u2013161. https:\/\/doi.org\/10.1016\/j.procbio.2016.11.025","journal-title":"Process Biochem"},{"issue":"8","key":"10735_CR54","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1007\/s10529-009-0003-8","volume":"31","author":"SJ Yeom","year":"2009","unstructured":"Yeom SJ, Kim NH, Yoon RY, Kwon HJ, Park CS, Oh DK (2009) Characterization of a mannose-6-phosphate isomerase from Geobacillus thermodenitrificans that converts monosaccharides. Biotechnol Lett 31(8):1273\u20131278. https:\/\/doi.org\/10.1007\/s10529-009-0003-8","journal-title":"Biotechnol Lett"},{"issue":"6","key":"10735_CR55","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1007\/s10529-010-0224-x","volume":"32","author":"SJ Yeom","year":"2010","unstructured":"Yeom SJ, Kim BN, Park CS, Oh DK (2010) Substrate specificity of ribose-5-phosphate isomerases from Clostridium difficile and Thermotoga maritima. Biotechnol Lett 32(6):829\u2013835. https:\/\/doi.org\/10.1007\/s10529-010-0224-x","journal-title":"Biotechnol Lett"},{"issue":"6","key":"10735_CR56","doi-asserted-by":"publisher","first-page":"1859","DOI":"10.1007\/s00253-010-3026-0","volume":"89","author":"SJ Yeom","year":"2011","unstructured":"Yeom SJ, Seo ES, Kim YS, Oh DK (2011) Increased D-allose production by the R132E mutant of ribose-5-phosphate isomerase from Clostridium thermocellum. Appl Microbiol Biotechnol 89(6):1859\u20131866. https:\/\/doi.org\/10.1007\/s00253-010-3026-0","journal-title":"Appl Microbiol Biotechnol"},{"issue":"3","key":"10735_CR57","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1128\/aem.02539-12","volume":"79","author":"SJ Yeom","year":"2013","unstructured":"Yeom SJ, Kim YS, Oh DK (2013) Development of novel sugar isomerases by optimization of active sites in phosphosugar isomerases for monosaccharides. Appl Environ Microbiol 79(3):982\u2013988. https:\/\/doi.org\/10.1128\/aem.02539-12","journal-title":"Appl Environ Microbiol"},{"issue":"1","key":"10735_CR58","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.jbiotec.2008.09.012","volume":"139","author":"RY Yoon","year":"2009","unstructured":"Yoon RY, Yeom SJ, Kim HJ, Oh DK (2009a) Novel substrates of a ribose-5-phosphate isomerase from Clostridium thermocellum. J Biotechnol 139(1):26\u201332. https:\/\/doi.org\/10.1016\/j.jbiotec.2008.09.012","journal-title":"J Biotechnol"},{"issue":"2","key":"10735_CR59","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1007\/s00253-009-1859-1","volume":"83","author":"RY Yoon","year":"2009","unstructured":"Yoon RY, Yeom SJ, Park CS, Oh DK (2009b) Substrate specificity of a glucose-6-phosphate isomerase from Pyrococcus furiosus for monosaccharides. Appl Microbiol Biotechnol 83(2):295\u2013303. https:\/\/doi.org\/10.1007\/s00253-009-1859-1","journal-title":"Appl Microbiol Biotechnol"},{"issue":"1","key":"10735_CR60","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/s0969-2126(02)00933-4","volume":"11","author":"RG Zhang","year":"2003","unstructured":"Zhang RG, Andersson CE, Savchenko A, Skarina T, Evdokimova E, Beasley S, Arrowsmith CH, Edwards AM, Joachimiak A, Mowbray SL (2003a) Structure of Escherichia coli ribose-5-phosphate isomerase: a ubiquitous enzyme of the pentose phosphate pathway and the Calvin cycle. Structure 11(1):31\u201342. https:\/\/doi.org\/10.1016\/s0969-2126(02)00933-4","journal-title":"Structure"},{"issue":"5","key":"10735_CR61","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1016\/j.jmb.2003.08.009","volume":"332","author":"RG Zhang","year":"2003","unstructured":"Zhang RG, Andersson CE, Skarina T, Evdokimova E, Edwards AM, Joachimiak A, Savchenko A, Mowbray SL (2003b) The 2.2 angstrom resolution structure of RpiB\/AlsB from Escherichia coli illustrates a new approach to the ribose-5-phosphate isomerase reaction. J Mol Biol 332(5):1083\u20131094. https:\/\/doi.org\/10.1016\/j.jmb.2003.08.009","journal-title":"J Mol Biol"},{"issue":"4","key":"10735_CR62","doi-asserted-by":"publisher","first-page":"e62987","DOI":"10.1371\/journal.pone.0062987","volume":"8","author":"W Zhang","year":"2013","unstructured":"Zhang W, Fang D, Xing Q, Zhou L, Jiang B, Mu W (2013) Characterization of a novel metal-dependent D-psicose 3-epimerase from Clostridium scindens 35704. PLoS One 8(4):e62987\u2013e62995. https:\/\/doi.org\/10.1371\/journal.pone.0062987","journal-title":"PLoS One"},{"key":"10735_CR63","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.tifs.2016.06.004","volume":"54","author":"W Zhang","year":"2016","unstructured":"Zhang W, Yu S, Zhang T, Jiang B, Mu W (2016) Recent advances in D-allulose: physiological functionalities, applications, and biological production. Trends Food Sci Technol 54:127\u2013137. https:\/\/doi.org\/10.1016\/j.tifs.2016.06.004","journal-title":"Trends Food Sci Technol"},{"issue":"2","key":"10735_CR64","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.biotechadv.2017.01.004","volume":"35","author":"W Zhang","year":"2017","unstructured":"Zhang W, Zhang T, Jiang B, Mu W (2017) Enzymatic approaches to rare sugar production. Biotechnol Adv 35(2):267\u2013274. https:\/\/doi.org\/10.1016\/j.biotechadv.2017.01.004","journal-title":"Biotechnol Adv"}],"container-title":["Applied Microbiology and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00253-020-10735-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00253-020-10735-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00253-020-10735-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T19:14:05Z","timestamp":1623438845000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00253-020-10735-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,12]]},"references-count":64,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10735"],"URL":"https:\/\/doi.org\/10.1007\/s00253-020-10735-4","relation":{},"ISSN":["0175-7598","1432-0614"],"issn-type":[{"value":"0175-7598","type":"print"},{"value":"1432-0614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,12]]},"assertion":[{"value":"1 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 June 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 June 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 June 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}