{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:17:55Z","timestamp":1786979875428,"version":"build-2736575974"},"reference-count":75,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100021856","name":"Ministero dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["This work has been funded by the European Union - NextGenerationEU under the Italian Ministry of University and Research (MUR) National Innovation Ecosystem grant ECS00000041 \u2013 VITALITY to CM and RB. We acknowledge Universit\u00e0 degli Studi di Perugia and MUR for support within the project Vitality."],"award-info":[{"award-number":["This work has been funded by the European Union - NextGenerationEU under the Italian Ministry of University and Research (MUR) National Innovation Ecosystem grant ECS00000041 \u2013 VITALITY to CM and RB. We acknowledge Universit\u00e0 degli Studi di Perugia and MUR for support within the project Vitality."]}],"id":[{"id":"10.13039\/501100021856","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010607","name":"Universit\u00e0 degli Studi di Perugia","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100010607","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Microbiol Biotechnol"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>\n                      Bacterial plant diseases are difficult to control as the durability of deployed control measures is thwarted by continuous and rapid changing of bacterial populations. Although application of copper compounds to plants is the most widespread and inexpensive control measure, it is often partially efficacious for the frequent appearance of copper-resistant bacterial strains and it is raising concerns for the harmful effects of copper on environment and human health. Consequently, European Community included copper compounds in the list of substances candidates for substitution. Nanotechnologies and the application of nanoparticles seem to respond to the need to find new very effective and durable measures. We believe that\n                      <jats:italic>Argirium<\/jats:italic>\n                      -\n                      <jats:italic>SUNCs<\/jats:italic>\n                      \u00ae, silver ultra nanoclusters with an average size of 1.79\u00a0nm and characterized by rare oxidative states (Ag\n                      <jats:sup>2+\/3+<\/jats:sup>\n                      ), represent a valid candidate as a nano-bactericide in the control of plant bacterial diseases. Respect to the many silver nanoparticles described in the literature,\n                      <jats:italic>Argirium<\/jats:italic>\n                      -\n                      <jats:italic>SUNCs<\/jats:italic>\n                      have many strengths due to the reproducibility of the synthesis method, the purity and the stability of the preparation, the very strong (less than 1 ppm) antimicrobial, and anti-biofilm activities. In this mini-review, we provide information on this nanomaterial and on the possible application in agriculture.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key points<\/jats:title>\n                    <jats:p>\n                      <jats:italic>\u2022 Argirium-SUNCs  have strong antimicrobial activities against phytopathogenic bacteria.<\/jats:italic>\n                    <\/jats:p>\n                    <jats:p>\n                      <jats:italic>\u2022 Argirium-SUNCs  are a possible plant protection product.<\/jats:italic>\n                    <\/jats:p>\n                    <jats:p>\n                      <jats:italic>\u2022 Argirium-SUNCs protect tomato plants against bacterial speck disease.<\/jats:italic>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Graphical Abstract<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1007\/s00253-024-13189-0","type":"journal-article","created":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T05:02:08Z","timestamp":1717218128000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Combat phytopathogenic bacteria employing Argirium-SUNCs: limits and perspectives"],"prefix":"10.1007","volume":"108","author":[{"given":"Benedetta","family":"Orfei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1500-7320","authenticated-orcid":false,"given":"Chiaraluce","family":"Moretti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Scian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michela","family":"Paglialunga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Loreti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Tatulli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Scotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Aceto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Buonaurio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,1]]},"reference":[{"key":"13189_CR1","doi-asserted-by":"publisher","first-page":"2509","DOI":"10.1007\/s10311-022-01430-z","volume":"20","author":"E Asmatulu","year":"2022","unstructured":"Asmatulu E, Andalib MN, Subeshan B, Abedin F (2022) Impact of nanomaterials on human health: a review. Environ Chem Lett 20:2509\u20132529. https:\/\/doi.org\/10.1007\/s10311-022-01430-z","journal-title":"Environ Chem Lett"},{"issue":"5","key":"13189_CR2","doi-asserted-by":"publisher","first-page":"5291","DOI":"10.1021\/acsnano.8b09781","volume":"13","author":"A Avellan","year":"2019","unstructured":"Avellan A, Yun J, Zhang Y, Spielman-Sun E, Unrine JM, Thieme J, Li J, Lombi E, Bland G, Lowry GV (2019) Nanoparticle size and coating chemistry control foliar uptake pathways, translocation, and leaf-to-rhizosphere transport in wheat. ACS Nano 13(5):5291\u20135305. https:\/\/doi.org\/10.1021\/acsnano.8b09781","journal-title":"ACS Nano"},{"issue":"20","key":"13189_CR3","doi-asserted-by":"publisher","first-page":"13417","DOI":"10.1021\/acs.est.1c00178","volume":"55","author":"A Avellan","year":"2021","unstructured":"Avellan A, Yun J, Morais BP, Clement ET, Rodrigues SM, Lowry GV (2021) Critical review: role of inorganic nanoparticle properties on their foliar uptake and in planta translocation. Environ Sci Technol 55(20):13417\u201313431. https:\/\/doi.org\/10.1021\/acs.est.1c00178","journal-title":"Environ Sci Technol"},{"issue":"3","key":"13189_CR4","first-page":"574","volume":"26","author":"M Ayisigi","year":"2020","unstructured":"Ayisigi M, Cokislerel A, Kucukcobanoglu Y, Yalcin T, Aktas LY (2020) Green synthesized silver nanoparticles for an effective control on soft rot disease pathogen Pectobacterium carotovorum and growth stimulation in pepper. Bulg J Agric Sci 26(3):574\u2013584","journal-title":"Bulg J Agric Sci"},{"key":"13189_CR5","volume-title":"Nanotechnology-based sustainable alternatives for the management of plant diseases","author":"GM Balestra","year":"2022","unstructured":"Balestra GM, Fortunati E (2022) Nanotechnology-based sustainable alternatives for the management of plant diseases. Elsevier, Amsterdam"},{"key":"13189_CR6","doi-asserted-by":"publisher","first-page":"32","DOI":"10.3389\/fpls.2016.00032","volume":"7","author":"D Bao","year":"2016","unstructured":"Bao D, Oh ZG, Chen Z (2016) Characterization of silver nanoparticles internalized by Arabidopsis plants using single particle ICP-MS analysis. Front Plant Sci 7:32. https:\/\/doi.org\/10.3389\/fpls.2016.00032","journal-title":"Front Plant Sci"},{"issue":"3","key":"13189_CR7","doi-asserted-by":"publisher","first-page":"79","DOI":"10.3390\/antibiotics7030079","volume":"7","author":"F Barras","year":"2018","unstructured":"Barras F, Aussel L, Ezraty B (2018) Silver and antibiotic, new facts to an old story. Antibiotics 7(3):79. https:\/\/doi.org\/10.3390\/antibiotics7030079","journal-title":"Antibiotics"},{"issue":"10","key":"13189_CR8","doi-asserted-by":"publisher","first-page":"1944","DOI":"10.1039\/c7en00555e","volume":"4","author":"NG Chavez Soria","year":"2017","unstructured":"Chavez Soria NG, Montes A, Bisson MA, Atilla-Gokcumen GE, Aga DS (2017) Mass spectrometry-based metabolomics to assess uptake of silver nanoparticles by Arabidopsis thaliana. Environ Sci Nano 4(10):1944\u20131953. https:\/\/doi.org\/10.1039\/c7en00555e","journal-title":"Environ Sci Nano"},{"key":"13189_CR9","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/j.envpol.2019.07.053","volume":"253","author":"P Courtois","year":"2019","unstructured":"Courtois P, Rorat A, Lemiere S, Guyoneaud R, Attard E, Levard C, Vandenbulcke F (2019) Ecotoxicology of silver nanoparticles and their derivatives introduced in soil with or without sewage sludge: a review of effects on microorganisms, plants and animals. Environ Pollut 253:578\u2013598. https:\/\/doi.org\/10.1016\/j.envpol.2019.07.053","journal-title":"Environ Pollut"},{"key":"13189_CR10","doi-asserted-by":"publisher","first-page":"5590","DOI":"10.1007\/s11356-017-0928-8","volume":"25","author":"P Cvjetko","year":"2018","unstructured":"Cvjetko P, Zovko M, \u0160tefani\u0107 PP, Biba R, Tkalec M, Domijan AM, Vr\u010dek IV, Letofsky-Papst I, \u0160iki\u0107 S, Balen B (2018) Phytotoxic effects of silver nanoparticles in tobacco plants. Environ Sci Pollut Res 25:5590\u20135602. https:\/\/doi.org\/10.1007\/s11356-017-0928-8","journal-title":"Environ Sci Pollut Res"},{"issue":"12","key":"13189_CR11","doi-asserted-by":"publisher","first-page":"1775","DOI":"10.3390\/nano9121775","volume":"9","author":"RE Duval","year":"2019","unstructured":"Duval RE, Gouyau J, Lamouroux E (2019) Limitations of recent studies dealing with the antibacterial properties of silver nanoparticles: fact and opinion. Nanomaterials 9(12):1775. https:\/\/doi.org\/10.3390\/nano9121775","journal-title":"Nanomaterials"},{"issue":"1","key":"13189_CR12","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1146\/annurev-phyto-080417-050108","volume":"56","author":"W Elmer","year":"2018","unstructured":"Elmer W, White JC (2018) The future of nanotechnology in plant pathology. Annu Rev Phytopathol 56(1):111\u2013133. https:\/\/doi.org\/10.1146\/annurev-phyto-080417-050108","journal-title":"Annu Rev Phytopathol"},{"issue":"2","key":"13189_CR13","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/j.envint.2010.10.012","volume":"37","author":"J Fabrega","year":"2011","unstructured":"Fabrega J, Luoma SN, Tyler CR, Galloway TS, Lead JR (2011) Silver nanoparticles: behaviour and effects in the aquatic environment. Environ Int 37(2):517\u2013531. https:\/\/doi.org\/10.1016\/j.envint.2010.10.012","journal-title":"Environ Int"},{"issue":"1","key":"13189_CR14","doi-asserted-by":"publisher","first-page":"129","DOI":"10.36253\/phyto-13282","volume":"61","author":"XJ Fan","year":"2022","unstructured":"Fan XJ, Saleem T, Zou HS (2022) Copper resistance mechanisms in plant pathogenic bacteria. Phytopathol Mediterr 61(1):129\u2013138. https:\/\/doi.org\/10.36253\/phyto-13282","journal-title":"Phytopathol Mediterr"},{"issue":"17","key":"13189_CR15","doi-asserted-by":"publisher","first-page":"5155","DOI":"10.3390\/molecules26175155","volume":"26","author":"C Gasbarri","year":"2021","unstructured":"Gasbarri C, Ronci M, Aceto A, Vasani R, Iezzi G, Florio T, Barbieri F, Angelini G, Scotti L (2021) Structure and properties of electrochemically synthesized silver nanoparticles in aqueous solution by high-resolution techniques. Molecules 26(17):5155. https:\/\/doi.org\/10.3390\/molecules26175155","journal-title":"Molecules"},{"key":"13189_CR16","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.3389\/fmicb.2020.01705","volume":"11","author":"R Grande","year":"2020","unstructured":"Grande R, Sisto F, Puca V, Carradori S, Ronci M, Aceto A, Muraro R, Mincione G, Scotti L (2020) Antimicrobial and antibiofilm activities of new synthesized silver ultra-nanoclusters (SUNCs) against Helicobacter pylori. Front Microbiol 11:1705. https:\/\/doi.org\/10.3389\/fmicb.2020.01705","journal-title":"Front Microbiol"},{"key":"13189_CR17","doi-asserted-by":"publisher","first-page":"1180632","DOI":"10.3389\/fpls.2023.1180632","volume":"14","author":"L Grandi","year":"2023","unstructured":"Grandi L, Oehl M, Lombardi T, de Michele VR, Schmitt N, Verweire D, Balmer D (2023) Innovations towards sustainable olive crop management: a new dawn by precision agriculture including endo-therapy. Front Plant Sci 14:1180632. https:\/\/doi.org\/10.3389\/fpls.2023.1180632","journal-title":"Front Plant Sci"},{"key":"13189_CR18","doi-asserted-by":"publisher","first-page":"124148","DOI":"10.1016\/j.jhazmat.2020.124148","volume":"404","author":"R Grillo","year":"2021","unstructured":"Grillo R, Fraceto LF, Amorim MJ, Scott-Fordsmand JJ, Schoonjans R, Chaudhry Q (2021) Ecotoxicological and regulatory aspects of environmental sustainability of nanopesticides. J Hazard Mater 404:124148. https:\/\/doi.org\/10.1016\/j.jhazmat.2020.124148","journal-title":"J Hazard Mater"},{"issue":"3","key":"13189_CR19","first-page":"147","volume":"57","author":"M Grzesik","year":"2012","unstructured":"Grzesik M, Janas R, G\u00f3rnik K, Romanowska-Duda Z (2012) Biological and physical methods of seed production and processing. J Res Appl Agric Eng 57(3):147\u2013152","journal-title":"J Res Appl Agric Eng"},{"issue":"5","key":"13189_CR20","doi-asserted-by":"publisher","first-page":"e09472","DOI":"10.1016\/j.heliyon.2022.e09472","volume":"8","author":"DS Guerrero","year":"2022","unstructured":"Guerrero DS, Bertani RP, Ledesma A, Fr\u00edas MD, Romero CM, Costa JSD (2022) Silver nanoparticles synthesized by the heavy metal resistant strain Amycolatopsis tucumanensis and its application in controlling red strip disease in sugarcane. Heliyon 8(5):e09472. https:\/\/doi.org\/10.1016\/j.heliyon.2022.e09472","journal-title":"Heliyon"},{"key":"13189_CR21","doi-asserted-by":"publisher","first-page":"118448","DOI":"10.1016\/j.envpol.2021.118448","volume":"292","author":"J He","year":"2022","unstructured":"He J, Zhang L, He SY, Ryser ET, Li H, Zhang W (2022) Stomata facilitate foliar sorption of silver nanoparticles by Arabidopsis thaliana. Environ Pollut 292:118448. https:\/\/doi.org\/10.1016\/j.envpol.2021.118448","journal-title":"Environ Pollut"},{"issue":"1","key":"13189_CR22","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1039\/d1en00870f","volume":"9","author":"D Huang","year":"2022","unstructured":"Huang D, Dang F, Huang Y, Chen N, Zhou D (2022) Uptake, translocation, and transformation of silver nanoparticles in plants. Environ Sci Nano 9(1):12\u201339. https:\/\/doi.org\/10.1039\/d1en00870f","journal-title":"Environ Sci Nano"},{"key":"13189_CR23","doi-asserted-by":"publisher","first-page":"1507","DOI":"10.1007\/s00299-016-1974-2","volume":"35","author":"T Ishii","year":"2016","unstructured":"Ishii T, Araki M (2016) Consumer acceptance of food crops developed by genome editing. Plant Cell Rep 35:1507\u20131518. https:\/\/doi.org\/10.1007\/s00299-016-1974-2","journal-title":"Plant Cell Rep"},{"issue":"8","key":"13189_CR24","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1038\/s41565-018-0131-1","volume":"13","author":"M Kah","year":"2018","unstructured":"Kah M, Kookana RS, Gogos A, Bucheli TD (2018) A critical evaluation of nanopesticides and nanofertilizers against their conventional analogues. Nat Nanatechnol 13(8):677\u2013684. https:\/\/doi.org\/10.1038\/s41565-018-0131-1","journal-title":"Nat Nanatechnol"},{"key":"13189_CR25","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1201\/b18892","volume-title":"Sustainable approaches to controlling plant pathogenic bacteria","author":"VR Kannan","year":"2015","unstructured":"Kannan VR, Bastas KK, Devi RS (2015) Scientific and economic impact of plant pathogenic bacteria. In: Kannan VR, Bastas KK (eds) Sustainable approaches to controlling plant pathogenic bacteria. CRC, Boca Raton, pp 369\u2013392"},{"key":"13189_CR26","doi-asserted-by":"publisher","first-page":"112844","DOI":"10.1016\/j.ecoenv.2021.112844","volume":"226","author":"AR Khan","year":"2021","unstructured":"Khan AR, Azhar W, Wu J, Ulhassan Z, Salam A, Zaidi SHR, Yang S, Song G, Gan Y (2021) Ethylene participates in zinc oxide nanoparticles induced biochemical, molecular and ultrastructural changes in rice seedlings. Ecotoxicol Environ Saf 226:112844. https:\/\/doi.org\/10.1016\/j.ecoenv.2021.112844","journal-title":"Ecotoxicol Environ Saf"},{"issue":"5","key":"13189_CR27","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.1007\/s11051-008-9513-x","volume":"11","author":"RA Khaydarov","year":"2009","unstructured":"Khaydarov RA, Khaydarov RR, Gapurova O, Estrin Y, Scheper T (2009) Electrochemical method for the synthesis of silver nanoparticles. J Nanopart Res 11(5):1193\u20131200. https:\/\/doi.org\/10.1007\/s11051-008-9513-x","journal-title":"J Nanopart Res"},{"issue":"3","key":"13189_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s13593-018-0503-9","volume":"38","author":"JR Lamichhane","year":"2018","unstructured":"Lamichhane JR, Osdaghi E, Behlau F, K\u00f6hl J, Jones JB, Aubertot JN (2018) Thirteen decades of antimicrobial copper compounds applied in agriculture. A review. Agron Sustain Dev 38(3):1\u201318. https:\/\/doi.org\/10.1007\/s13593-018-0503-9","journal-title":"Agron Sustain Dev"},{"key":"13189_CR29","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.jhazmat.2013.10.053","volume":"264","author":"C Larue","year":"2014","unstructured":"Larue C, Castillo-Michel H, Sobanska S, C\u00e9cillon L, Bureau S, Barth\u00e8s V, Ouerdane L, Carri\u00e8re M, Sarret G (2014) Foliar exposure of the crop Lactuca sativa to silver nanoparticles: evidence for internalization and changes in Ag speciation. J Hazar Mater 264:98\u2013106. https:\/\/doi.org\/10.1016\/j.jhazmat.2013.10.053","journal-title":"J Hazar Mater"},{"issue":"62","key":"13189_CR30","doi-asserted-by":"publisher","first-page":"38853","DOI":"10.1039\/c7ra05520j","volume":"7","author":"Y Li","year":"2017","unstructured":"Li Y, Yang D, Cui J (2017) Graphene oxide loaded with copper oxide nanoparticles as an antibacterial agent against Pseudomonas syringae Pv. Tomato. RSC Adv 7(62):38853\u201338860. https:\/\/doi.org\/10.1039\/c7ra05520j","journal-title":"RSC Adv"},{"issue":"6","key":"13189_CR31","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1038\/s41565-019-0461-7","volume":"14","author":"GV Lowry","year":"2019","unstructured":"Lowry GV, Avellan A, Gilbertson LM (2019) Opportunities and challenges for nanotechnology in the agri-tech revolution. Nat Nanatechnol 14(6):517\u2013522. https:\/\/doi.org\/10.1038\/s41565-019-0461-7","journal-title":"Nat Nanatechnol"},{"issue":"1","key":"13189_CR32","doi-asserted-by":"publisher","first-page":"109","DOI":"10.3390\/antibiotics13010109","volume":"13","author":"A Mancusi","year":"2024","unstructured":"Mancusi A, Egidio M, Marrone R, Scotti L, Paludi D, Dini I, Proroga YTR (2024) The in vitro antibacterial activity of Argirium SUNc against most common pathogenic and spoilage food bacteria. Antibiotics 13(1):109. https:\/\/doi.org\/10.3390\/antibiotics13010109","journal-title":"Antibiotics"},{"issue":"6","key":"13189_CR33","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1111\/j.1364-3703.2012.00804.x","volume":"13","author":"J Mansfield","year":"2012","unstructured":"Mansfield J, Genin S, Magori S, Citovsky V, Sriariyanum M, Ronald P, Dow M, Verdier V, Beer SV, Machado MA (2012) Top 10 plant pathogenic bacteria in molecular plant pathology. Mol Plant Pathol 13(6):614\u2013629. https:\/\/doi.org\/10.1111\/j.1364-3703.2012.00804.x","journal-title":"Mol Plant Pathol"},{"issue":"1","key":"13189_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-021-00545-7","volume":"11","author":"JB Molina-Hernandez","year":"2021","unstructured":"Molina-Hernandez JB, Aceto A, Bucciarelli T, Paludi D, Valbonetti L, Zilli K, Scotti L, Chaves-L\u00f3pez C (2021) The membrane depolarization and increase intracellular calcium level produced by silver nanoclusters are responsible for bacterial death. Sci Rep 11(1):1\u201313. https:\/\/doi.org\/10.1038\/s41598-021-00545-7","journal-title":"Sci Rep"},{"issue":"1","key":"13189_CR35","doi-asserted-by":"publisher","first-page":"2716","DOI":"10.1038\/s41598-023-29918-w","volume":"13","author":"JB Molina-Hernandez","year":"2023","unstructured":"Molina-Hernandez JB, Scotti L, Valbonetti L, Gioia L, Paparella A, Paludi D, Aceto A, Ciriolo MR, Lopez CC (2023) Effect of membrane depolarization against Aspergillus Niger GM31 resistant by ultra nanoclusters characterized by Ag2+ and Ag3+ oxidation state. Sci Rep 13(1):2716. https:\/\/doi.org\/10.1038\/s41598-023-29918-w","journal-title":"Sci Rep"},{"issue":"2","key":"13189_CR36","doi-asserted-by":"publisher","first-page":"369","DOI":"10.3390\/microorganisms11020369","volume":"11","author":"PR More","year":"2023","unstructured":"More PR, Pandit S, Filippis AD, Franci G, Mijakovic I, Galdiero M (2023) Silver nanoparticles: bactericidal and mechanistic approach against drug resistant pathogens. Microorganisms 11(2):369. https:\/\/doi.org\/10.3390\/microorganisms11020369","journal-title":"Microorganisms"},{"key":"13189_CR37","volume-title":"Hydroponic tomato crop production","author":"L Morgan","year":"2008","unstructured":"Morgan L (2008) Hydroponic tomato crop production. Suntec Ltd, Tokomaru"},{"issue":"9","key":"13189_CR38","doi-asserted-by":"publisher","first-page":"1975","DOI":"10.1007\/s00449-021-02579-7","volume":"44","author":"KR Namburi","year":"2021","unstructured":"Namburi KR, Kora AJ, Chetukuri A, Kota V (2021) Biogenic silver nanoparticles as an antibacterial agent against bacterial leaf blight causing rice phytopathogen Xanthomonas oryzae Pv. Oryzae. Bioprocess Biosyst Eng 44(9):1975\u20131988. https:\/\/doi.org\/10.1007\/s00449-021-02579-7","journal-title":"Bioprocess Biosyst Eng"},{"issue":"5","key":"13189_CR39","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1007\/s00216-009-3081-5","volume":"395","author":"KF Nielsen","year":"2009","unstructured":"Nielsen KF, Mogensen JM, Johansen M, Larsen TO, Frisvad JC (2009) Review of secondary metabolites and mycotoxins from the Aspergillus Niger group. Anal Bioanal Chem 395(5):1225\u20131242. https:\/\/doi.org\/10.1007\/s00216-009-3081-5","journal-title":"Anal Bioanal Chem"},{"issue":"1","key":"13189_CR40","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1080\/15226514.2019.1634000","volume":"22","author":"A Noori","year":"2020","unstructured":"Noori A, Donnelly T, Colbert J, Cai W, Newman LA, White JC (2020) Exposure of tomato (Lycopersicon esculentum) to silver nanoparticles and silver nitrate: physiological and molecular response. Int J Phytorem 22(1):40\u201351. https:\/\/doi.org\/10.1080\/15226514.2019.1634000","journal-title":"Int J Phytorem"},{"key":"13189_CR41","doi-asserted-by":"publisher","first-page":"4519","DOI":"10.1007\/s00253-023-12596-z","volume":"107","author":"B Orfei","year":"2023","unstructured":"Orfei B, Moretti C, Loreti S, Tatulli G, Onofri A, Scotti L, Aceto A, Buonaurio R (2023a) Silver nanoclusters with Ag2+\/3+ oxidative states are a new highly effective tool against phytopathogenic bacteria. Appl Microbiol Biotechnol 107:4519\u20134531. https:\/\/doi.org\/10.1007\/s00253-023-12596-z","journal-title":"Appl Microbiol Biotechnol"},{"key":"13189_CR42","doi-asserted-by":"publisher","first-page":"1197706","DOI":"10.3389\/fpls.2023.1197706","volume":"14","author":"B Orfei","year":"2023","unstructured":"Orfei B, Pothier JF, Fenske L, Blom J, Moretti C, Buonaurio R, Smits THM (2023b) Race-specific genotypes of Pseudomonas syringae Pv. Tomato are defined by the presence of mobile DNA elements within the genome. Front Plant Sci 14:1197706. https:\/\/doi.org\/10.3389\/fpls.2023.1197706","journal-title":"Front Plant Sci"},{"key":"13189_CR43","doi-asserted-by":"publisher","first-page":"138","DOI":"10.3389\/fmicb.2013.00138","volume":"4","author":"JA Perry","year":"2013","unstructured":"Perry JA, Wright GD (2013) The antibiotic resistance mobilome: searching for the link between environment and clinic. Front Microbiol 4:138. https:\/\/doi.org\/10.3389\/fmicb.2013.00138","journal-title":"Front Microbiol"},{"key":"13189_CR44","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.3389\/fmicb.2018.01349","volume":"9","author":"A Pompilio","year":"2018","unstructured":"Pompilio A, Geminiani C, Bosco D, Rana R, Aceto A, Bucciarelli T, Scotti L, Di Bonaventura G (2018) Electrochemically synthesized silver nanoparticles are active against planktonic and biofilm cells of Pseudomonas aeruginosa and other cystic fibrosis-associated bacterial pathogens. Front Microbiol 9:1349. https:\/\/doi.org\/10.3389\/fmicb.2018.01349","journal-title":"Front Microbiol"},{"key":"13189_CR45","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.3389\/fmicb.2017.01014","volume":"8","author":"R Prasad","year":"2017","unstructured":"Prasad R, Bhattacharyya A, Nguyen QD (2017) Nanotechnology in sustainable agriculture: recent developments, challenges, and perspectives. Front Microbiol 8:1014. https:\/\/doi.org\/10.3389\/fmicb.2017.01014","journal-title":"Front Microbiol"},{"issue":"23","key":"13189_CR46","doi-asserted-by":"publisher","first-page":"e2022239118","DOI":"10.1073\/pnas.2022239118","volume":"118","author":"JB Ristaino","year":"2021","unstructured":"Ristaino JB, Anderson PK, Bebber DP, Brauman KA, Cunniffe NJ, Fedoroff NV, Finegold C, Garrett KA, Gilligan CA, Jones CM (2021) The persistent threat of emerging plant disease pandemics to global food security. Proc Natl Acad Sci 118(23):e2022239118. https:\/\/doi.org\/10.1073\/pnas.2022239118","journal-title":"Proc Natl Acad Sci"},{"issue":"4","key":"13189_CR47","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1039\/c6en00573j","volume":"4","author":"SM Rodrigues","year":"2017","unstructured":"Rodrigues SM, Demokritou P, Dokoozlian N, Hendren CO, Karn B, Mauter MS, Sadik OA, Safarpour M, Unrine JM, Viers J (2017) Nanotechnology for sustainable food production: promising opportunities and scientific challenges. Environ Sci Nano 4(4):767\u2013781. https:\/\/doi.org\/10.1039\/c6en00573j","journal-title":"Environ Sci Nano"},{"issue":"2","key":"13189_CR48","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1094\/phyto-08-18-0319-fi","volume":"109","author":"M Saponari","year":"2019","unstructured":"Saponari M, Giampetruzzi A, Loconsole G, Boscia D, Saldarelli P (2019) Xylella fastidiosa in olive in Apulia: where we stand. Phytopathology 109(2):175\u2013186. https:\/\/doi.org\/10.1094\/phyto-08-18-0319-fi","journal-title":"Phytopathology"},{"key":"13189_CR49","doi-asserted-by":"publisher","unstructured":"Saritha GNG, Anju T, Kumar A (2022) Nanotechnology- big impact: how nanotechnology is changing the future of agriculture? J Agric Food Res 100457. https:\/\/doi.org\/10.1016\/j.jafr.2022.100457","DOI":"10.1016\/j.jafr.2022.100457"},{"issue":"3","key":"13189_CR50","doi-asserted-by":"publisher","first-page":"257","DOI":"10.3109\/17435390.2015.1048326","volume":"10","author":"F Schwab","year":"2016","unstructured":"Schwab F, Zhai G, Kern M, Turner A, Schnoor JL, Wiesner MR (2016) Barriers, pathways and processes for uptake, translocation and accumulation of nanomaterials in plants\u2013critical review. Nanotoxicology 10(3):257\u2013278. https:\/\/doi.org\/10.3109\/17435390.2015.1048326","journal-title":"Nanotoxicology"},{"issue":"7","key":"13189_CR51","doi-asserted-by":"publisher","first-page":"e05327","DOI":"10.2903\/j.efsa.2018.5327","volume":"16","author":"EFSA Scientific Committee","year":"2018","unstructured":"Scientific Committee EFSA, Hardy A, Benford D, Halldorsson T, Jeger MJ, Knutsen HK, More S, Naegeli H, Noteborn H, Ockleford C (2018) Guidance on risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain: part 1, human and animal health. EFSA J 16(7):e05327. https:\/\/doi.org\/10.2903\/j.efsa.2018.5327","journal-title":"EFSA J"},{"key":"13189_CR52","doi-asserted-by":"publisher","unstructured":"Scotti L, Angelini G, Gasbarri C, Bucciarelli T (2017) Uncoated negatively charged silver nanoparticles: speeding up the electrochemical synthesis. Mater Res Express 4. https:\/\/doi.org\/10.1088\/2053-1591\/aa8c39","DOI":"10.1088\/2053-1591\/aa8c39"},{"key":"13189_CR53","volume-title":"Scientific review of the impact of climate change on plant pests","author":"IPPC Secretariat","year":"2021","unstructured":"Secretariat IPPC, Gullino M, Albajes R, Al-Jboory I, Angelotti F, Chakraborty S, Garrett K, Hurley B, Juroszek P, Makkouk K (2021) Scientific review of the impact of climate change on plant pests. FAO on behalf of the IPPC Secretariat, Rome"},{"issue":"24","key":"13189_CR54","doi-asserted-by":"publisher","first-page":"2650","DOI":"10.2174\/1381612825666190708185506","volume":"25","author":"R Shanmuganathan","year":"2019","unstructured":"Shanmuganathan R, Karuppusamy I, Saravanan M, Muthukumar H, Ponnuchamy K, Ramkumar VS, Pugazhendhi A (2019) Synthesis of silver nanoparticles and their biomedical applications-a comprehensive review. Curr Pharm Des 25(24):2650\u20132660. https:\/\/doi.org\/10.2174\/1381612825666190708185506","journal-title":"Curr Pharm Des"},{"issue":"1","key":"13189_CR55","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1146\/annurev-phyto-021621-121806","volume":"60","author":"A Sharma","year":"2022","unstructured":"Sharma A, Abrahamian P, Carvalho R, Choudhary M, Paret ML, Vallad GE, Jones JB (2022) Future of bacterial disease management in crop production. Annu Rev Phytopathol 60(1):259\u2013282. https:\/\/doi.org\/10.1146\/annurev-phyto-021621-121806","journal-title":"Annu Rev Phytopathol"},{"issue":"4","key":"13189_CR56","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1007\/s10482-023-01809-0","volume":"116","author":"A Sharma","year":"2023","unstructured":"Sharma A, Gupta AK, Devi B (2023) Current trends in management of bacterial pathogens infecting plants. Anton Leeuw Int J G 116(4):303\u2013326. https:\/\/doi.org\/10.1007\/s10482-023-01809-0","journal-title":"Anton Leeuw Int J G"},{"key":"13189_CR57","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1146\/annurev-phyto-080417-045849","volume":"56","author":"A Sicard","year":"2018","unstructured":"Sicard A, Zeilinger AR, Vanhove M, Schartel TE, Beal DJ, Daugherty MP, Almeida RP (2018) Xylella fastidiosa: insights into an emerging plant pathogen. Annu Rev Phytopathol 56:181\u2013202. https:\/\/doi.org\/10.1146\/annurev-phyto-080417-045849","journal-title":"Annu Rev Phytopathol"},{"issue":"1","key":"13189_CR58","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12951-018-0334-5","volume":"16","author":"KS Siddiqi","year":"2018","unstructured":"Siddiqi KS, Husen A, Rao RA (2018) A review on biosynthesis of silver nanoparticles and their biocidal properties. J Nanobiotechnol 16(1):1\u201328. https:\/\/doi.org\/10.1186\/s12951-018-0334-5","journal-title":"J Nanobiotechnol"},{"issue":"8","key":"13189_CR59","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1007\/s13204-014-0396-0","volume":"5","author":"R Singaravelan","year":"2015","unstructured":"Singaravelan R, Bangaru Sudarsan Alwar S (2015) Electrochemical synthesis, characterisation and phytogenic properties of silver nanoparticles. Appl Nanosci 5(8):983\u2013991. https:\/\/doi.org\/10.1007\/s13204-014-0396-0","journal-title":"Appl Nanosci"},{"issue":"2","key":"13189_CR60","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1039\/d0em00404a","volume":"23","author":"H Singh","year":"2021","unstructured":"Singh H, Sharma A, Bhardwaj SK, Arya SK, Bhardwaj N, Khatri M (2021) Recent advances in the applications of nano-agrochemicals for sustainable agricultural development. Environ Sci Process Impacts 23(2):213\u2013239. https:\/\/doi.org\/10.1039\/d0em00404a","journal-title":"Environ Sci Process Impacts"},{"issue":"7376","key":"13189_CR61","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1038\/nature10571","volume":"480","author":"CS Smillie","year":"2011","unstructured":"Smillie CS, Smith MB, Friedman J, Cordero OX, David LA, Alm EJ (2011) Ecology drives a global network of gene exchange connecting the human microbiome. Nature 480(7376):241\u2013244. https:\/\/doi.org\/10.1038\/nature10571","journal-title":"Nature"},{"issue":"14","key":"13189_CR62","doi-asserted-by":"publisher","first-page":"8451","DOI":"10.1021\/acs.est.5b01147","volume":"49","author":"J Stegemeier","year":"2015","unstructured":"Stegemeier J, Schwab F, Colman B, Bernhardt E, Wiesner M, Lowry G (2015) Speciation matters - bioavailability of silver and silver sulfide nanoparticles to alfalfa (Medicago sativa). Environ Sci Technol 49(14):8451\u20138460. https:\/\/doi.org\/10.1021\/acs.est.5b01147","journal-title":"Environ Sci Technol"},{"key":"13189_CR63","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1146\/annurev-phyto-080417-045946","volume":"56","author":"GW Sundin","year":"2018","unstructured":"Sundin GW, Wang N (2018) Antibiotic resistance in plant-pathogenic bacteria. Annu Rev Phytopathol 56:161\u2013180. https:\/\/doi.org\/10.1146\/annurev-phyto-080417-045946","journal-title":"Annu Rev Phytopathol"},{"issue":"9","key":"13189_CR64","doi-asserted-by":"publisher","first-page":"1506","DOI":"10.1111\/mpp.12436","volume":"17","author":"GW Sundin","year":"2016","unstructured":"Sundin GW, Castiblanco LF, Yuan XC, Zeng Q, Yang CH (2016) Bacterial disease management: challenges, experience, innovation and future prospects. Mol Plant Pathol 17(9):1506\u20131518. https:\/\/doi.org\/10.1111\/mpp.12436","journal-title":"Mol Plant Pathol"},{"issue":"15","key":"13189_CR65","doi-asserted-by":"publisher","first-page":"4754","DOI":"10.3390\/molecules27154754","volume":"27","author":"M Tariq","year":"2022","unstructured":"Tariq M, Mohammad KN, Ahmed B, Siddiqui MA, Lee J (2022) Biological synthesis of silver nanoparticles and prospects in plant disease management. Molecules 27(15):4754. https:\/\/doi.org\/10.3390\/molecules27154754","journal-title":"Molecules"},{"key":"13189_CR66","doi-asserted-by":"publisher","DOI":"10.1201\/9780429242786","volume-title":"Phytopathogenic bacteria and plant diseases","author":"B Thind","year":"2019","unstructured":"Thind B (2019) Phytopathogenic bacteria and plant diseases. CRC Press, Boca Raton"},{"key":"13189_CR67","doi-asserted-by":"publisher","first-page":"1125685","DOI":"10.3389\/fmicb.2023.1125685","volume":"14","author":"J Trzcinska-Wencel","year":"2023","unstructured":"Trzcinska-Wencel J, Wypij M, Rai M, Golinska P (2023a) Biogenic nanosilver bearing antimicrobial and antibiofilm activities and its potential for application in agriculture and industry. Front Microbiol 14:1125685. https:\/\/doi.org\/10.3389\/fmicb.2023.1125685","journal-title":"Front Microbiol"},{"key":"13189_CR68","doi-asserted-by":"publisher","first-page":"1235437","DOI":"10.3389\/fchem.2023.1235437","volume":"11","author":"J Trzcinska-Wencel","year":"2023","unstructured":"Trzcinska-Wencel J, Wypij M, Terzyk AP, Rai M, Golinska P (2023b) Biofabrication of novel silver and zinc oxide nanoparticles from Fusarium solani IOR 825 and their potential application in agriculture as biocontrol agents of phytopathogens, and seed germination and seedling growth promoters. Front Chem 11:1235437. https:\/\/doi.org\/10.3389\/fchem.2023.1235437","journal-title":"Front Chem"},{"key":"13189_CR69","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.jbiotec.2019.12.009","volume":"309","author":"GL Vanti","year":"2020","unstructured":"Vanti GL, Kurjogi M, Basavesha KN, Teradal NL, Masaphy S, Nargund VB (2020) Synthesis and antibacterial activity of Solanum torvum mediated silver nanoparticle against Xanthomonas axonopodis Pv. Punicae and Ralstonia solanacearum. J Biotech 309:20\u201328. https:\/\/doi.org\/10.1016\/j.jbiotec.2019.12.009","journal-title":"J Biotech"},{"key":"13189_CR70","first-page":"1","volume-title":"Reducing agents in colloidal nanoparticle synthesis","author":"G Villaverde-Cantizano","year":"2021","unstructured":"Villaverde-Cantizano G, Laurenti M, Rubio-Retama J, Contreras-C\u00e1ceres R (2021) In: Mourdikoudis S (ed) Reducing agents in colloidal nanoparticle synthesis. RSC, London, pp 1\u201327"},{"issue":"6","key":"13189_CR71","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1080\/05704928.2019.1684303","volume":"55","author":"X Wang","year":"2020","unstructured":"Wang X, Yang H, Li K, Xiang Y, Sha Y, Zhang M, Yuan X, Huang K (2020) Recent developments of the speciation analysis methods for silver nanoparticles and silver ions based on atomic spectrometry. Appl Spectrosc Rev 55(6):509\u2013524. https:\/\/doi.org\/10.1080\/05704928.2019.1684303","journal-title":"Appl Spectrosc Rev"},{"key":"13189_CR72","doi-asserted-by":"publisher","first-page":"1030261","DOI":"10.3389\/fmicb.2022.1030261","volume":"13","author":"ZL Wei","year":"2022","unstructured":"Wei ZL, Xu SQ, Jia HR, Zhang HM (2022) Green synthesis of silver nanoparticles from Mahonia fortunei extracts and characterization of its inhibitory effect on Chinese cabbage soft rot pathogen. Front Microbiol 13:1030261. https:\/\/doi.org\/10.3389\/fmicb.2022.1030261","journal-title":"Front Microbiol"},{"issue":"20","key":"13189_CR73","doi-asserted-by":"publisher","first-page":"8996","DOI":"10.7150\/thno.45413","volume":"10","author":"L Xu","year":"2020","unstructured":"Xu L, Wang YY, Huang J, Chen CY, Wang ZX, Xie H (2020) Silver nanoparticles: synthesis, medical applications and biosafety. Theranostics 10(20):8996\u20139031. https:\/\/doi.org\/10.7150\/thno.45413","journal-title":"Theranostics"},{"issue":"3","key":"13189_CR74","doi-asserted-by":"publisher","first-page":"2097","DOI":"10.1007\/s10311-021-01338-0","volume":"20","author":"Z Xu","year":"2022","unstructured":"Xu Z, Tang T, Lin Q, Yu J, Zhang C, Zhao X, Kah M, Li L (2022) Environmental risks and the potential benefits of nanopesticides: a review. Environ Chem Lett 20(3):2097\u20132108. https:\/\/doi.org\/10.1007\/s10311-021-01338-0","journal-title":"Environ Chem Lett"},{"key":"13189_CR75","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1007\/s13204-020-01318-w","volume":"10","author":"AA Yaqoob","year":"2020","unstructured":"Yaqoob AA, Umar K, Ibrahim MNM (2020) Silver nanoparticles: various methods of synthesis, size affecting factors and their potential applications\u2013a review. Appl Nanosci 10:1369\u20131378. https:\/\/doi.org\/10.1007\/s13204-020-01318-w","journal-title":"Appl Nanosci"}],"container-title":["Applied Microbiology and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00253-024-13189-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00253-024-13189-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00253-024-13189-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T16:46:27Z","timestamp":1748364387000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00253-024-13189-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,1]]},"references-count":75,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["13189"],"URL":"https:\/\/doi.org\/10.1007\/s00253-024-13189-0","relation":{},"ISSN":["0175-7598","1432-0614"],"issn-type":[{"value":"0175-7598","type":"print"},{"value":"1432-0614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,1]]},"assertion":[{"value":"26 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 June 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This article complies with ethical standards and does not contain any studies with human participants or animal performed by any of the authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"<!--Emphasis Type='Bold' removed-->Conflict of interest"}}],"article-number":"357"}}