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Examples of these pathogens are methicillin-resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (MRSA) and the emergence of \u201cpan-resistant\u201d Gram-negative strains, such as <jats:italic>Pseudomonas aeruginosa<\/jats:italic> and <jats:italic>Acinetobacter baumannii<\/jats:italic>, which occurred more recently. This review examines various emerging materials with significant antibacterial activities. Among these are nanomaterials such as quantum dots, carbon quantum dots, metal\u2013organic frameworks (MOFs), covalent organic frameworks (COFs), and layered double hydroxides, all of which demonstrate excellent antibacterial properties. Interestingly, including antibacterial agents within the structure of these materials can help avoid bacterial resistance and improve the long-term efficacy of the materials. Additionally, the antibacterial potential of liquid solvents, including ionic liquids and both deep eutectic solvents and natural deep eutectic solvents, is explored. The review discusses the synthesis methods, advantages, and antibacterial efficacy of these new materials. By providing a comprehensive overview of these innovative materials, this review aims to contribute to the ongoing search for effective solutions to combat antibiotic resistance. Key studies demonstrating antibacterial effects against pathogens like <jats:italic>Escherichia coli<\/jats:italic>, <jats:italic>Staphylococcus aureus<\/jats:italic>, and multidrug-resistant strains are summarized. MOFs have exhibited antibacterial properties through controlled ion release and surface interactions. COFs have enhanced the efficacy of encapsulated antibiotics and displayed intrinsic antibacterial activity. Other nanomaterials, such as quantum dots, have generated reactive oxygen species, leading to microbial inactivation. This review aims to provide insights into these new classes of antibacterial materials and highlight them for addressing the global crisis of antibiotic resistance.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Key points<\/jats:title>\n            <jats:p>\n              <jats:italic>\u2022 Nanomaterials show strong antibacterial effects against drug-resistant bacteria<\/jats:italic>\n            <\/jats:p>\n            <jats:p>\n              <jats:italic>\u2022 Emerging solvents like ionic liquids offer novel solutions for bacterial resistance<\/jats:italic>\n            <\/jats:p>\n            <jats:p>\n              <jats:italic>\u2022 MOFs and COFs enhance antibiotic efficacy, showing promise in combating resistance<\/jats:italic>\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00253-024-13337-6","type":"journal-article","created":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T13:03:49Z","timestamp":1731589429000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["New emerging materials with potential antibacterial activities"],"prefix":"10.1007","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4263-0575","authenticated-orcid":false,"given":"Hadeer M.","family":"Bedair","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3890-1409","authenticated-orcid":false,"given":"Mahmoud","family":"Hamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0847-4035","authenticated-orcid":false,"given":"Fotouh R.","family":"Mansour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,14]]},"reference":[{"key":"13337_CR1","doi-asserted-by":"publisher","unstructured":"Abbott AP, Capper G, Davies DL, Rasheed RK, Tambyrajah V (2003) Novel solvent properties of choline chloride\/urea mixturesElectronic supplementary information (ESI) available: spectroscopic data. 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