{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T12:01:11Z","timestamp":1777982471570,"version":"3.51.4"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T00:00:00Z","timestamp":1772582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"National Key Research and Development Program of China","award":["2022YFC2105602"],"award-info":[{"award-number":["2022YFC2105602"]}]},{"DOI":"10.13039\/501100012131","name":"Department of Science and Technology of Liaoning Province","doi-asserted-by":"publisher","award":["2024JH2\/102600031"],"award-info":[{"award-number":["2024JH2\/102600031"]}],"id":[{"id":"10.13039\/501100012131","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Science and Technology of Liaoning Province","award":["2025-MS-005"],"award-info":[{"award-number":["2025-MS-005"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Microbiol Biotechnol"],"DOI":"10.1007\/s00253-026-13756-7","type":"journal-article","created":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T21:34:37Z","timestamp":1772660077000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unveiling a catalytically promiscuous feruloyl esterase from Clostridium acetobutylicum"],"prefix":"10.1007","volume":"110","author":[{"given":"Shang","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaowang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyu","family":"Che","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Quan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianglong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanbin","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Song","family":"Xue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,4]]},"reference":[{"key":"13756_CR1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00289-17","volume":"83","author":"T Cerisy","year":"2017","unstructured":"Cerisy T, Souterre T, Torres-Romero I, Boutard M, Dubois I, Patrouix J, Labadie K, Berrabah W, Salanoubat M, Doring V, Tolonen AC (2017) Evolution of a biomass-fermenting bacterium to resist lignin phenolics. Appl Environ Microbiol 83:e00289-17. https:\/\/doi.org\/10.1128\/AEM.00289-17","journal-title":"Appl Environ Microbiol"},{"issue":"14","key":"13756_CR2","doi-asserted-by":"publisher","first-page":"5549","DOI":"10.1007\/s00253-019-09916-7","volume":"103","author":"C Cheng","year":"2019","unstructured":"Cheng C, Bao T, Yang S-T (2019) Engineering Clostridium for improved solvent production: recent progress and perspective. Appl Microbiol Biotechnol 103(14):5549\u20135566. https:\/\/doi.org\/10.1007\/s00253-019-09916-7","journal-title":"Appl Microbiol Biotechnol"},{"key":"13756_CR3","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.procbio.2022.01.021","volume":"114","author":"G Du","year":"2022","unstructured":"Du G, Wu Y, Kang W, Xu Y, Li S, Xue C (2022) Enhanced butanol production in Clostridium acetobutylicum by manipulating metabolic pathway genes. Process Biochem 114:134\u2013138. https:\/\/doi.org\/10.1016\/j.procbio.2022.01.021","journal-title":"Process Biochem"},{"key":"13756_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.126540","volume":"253","author":"G Du","year":"2023","unstructured":"Du G, Wang Y, Zhang Y, Yu H, Liu S, Ma X, Cao H, Wei X, Wen B, Li Z, Fan S, Zhou H, Xin F (2023) Structural insights into the oligomeric effects on catalytic activity of a decameric feruloyl esterase and its application in ferulic acid production. Int J Biol Macromol 253:126540. https:\/\/doi.org\/10.1016\/j.ijbiomac.2023.126540","journal-title":"Int J Biol Macromol"},{"issue":"4","key":"13756_CR5","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1107\/s0907444910007493","volume":"66","author":"P Emsley","year":"2010","unstructured":"Emsley P, Lohkamp B, Scott WG, Cowtan K (2010) Features and development of Coot. Acta Crystallogr Sect D Biol Crystallogr 66(4):486\u2013501. https:\/\/doi.org\/10.1107\/s0907444910007493","journal-title":"Acta Crystallogr Sect D Biol Crystallogr"},{"key":"13756_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.biombioe.2024.107262","volume":"186","author":"S Farmanbordar","year":"2024","unstructured":"Farmanbordar S, Javid A, Amiri H, Denayer JFM, Karimi K (2024) Enhanced biobutanol production with sustainable co-substrates synergy from paper waste and garden waste with municipal biowaste. Biomass Bioenerg 186:107262. https:\/\/doi.org\/10.1016\/j.biombioe.2024.107262","journal-title":"Biomass Bioenerg"},{"issue":"8","key":"13756_CR7","doi-asserted-by":"publisher","first-page":"4962","DOI":"10.1016\/j.biortech.2011.01.088","volume":"102","author":"CB Faulds","year":"2011","unstructured":"Faulds CB, P\u00e9rez-Boada M, Mart\u00ednez \u00c1T (2011) Influence of organic co-solvents on the activity and substrate specificity of feruloyl esterases. Bioresour Technol 102(8):4962\u20134967. https:\/\/doi.org\/10.1016\/j.biortech.2011.01.088","journal-title":"Bioresour Technol"},{"issue":"6","key":"13756_CR8","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1002\/prot.22662","volume":"78","author":"DC Goldstone","year":"2010","unstructured":"Goldstone DC, Villas-B\u00f4as SG, Till M, Kelly WJ, Attwood GT, Arcus VL (2010) Structural and functional characterization of a promiscuous feruloyl esterase (Est1E) from the rumen bacterium Butyrivibrio proteoclasticus. Proteins 78(6):1457\u20131469. https:\/\/doi.org\/10.1002\/prot.22662","journal-title":"Proteins"},{"key":"13756_CR9","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.1050160","volume":"13","author":"KM Kasmaei","year":"2022","unstructured":"Kasmaei KM, Kalyani DC, Reichenbach T, Jim\u00e9nez-Quero A, Vilaplana F, Divne C (2022) Crystal structure of the feruloyl esterase from Lentilactobacillus buchneri reveals a novel homodimeric state. Front Microbiol 13:1050160. https:\/\/doi.org\/10.3389\/fmicb.2022.1050160","journal-title":"Front Microbiol"},{"issue":"21","key":"13756_CR10","doi-asserted-by":"publisher","first-page":"2947","DOI":"10.1093\/bioinformatics\/btm404","volume":"23","author":"MA Larkin","year":"2007","unstructured":"Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, McWilliam H, Valentin F, Wallace IM, Wilm A, Lopez R, Thompson JD, Gibson TJ, Higgins DG (2007) Clustal W and Clustal X version 2.0. Bioinformatics 23(21):2947\u20132948. https:\/\/doi.org\/10.1093\/bioinformatics\/btm404","journal-title":"Bioinformatics"},{"key":"13756_CR11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.123365","volume":"232","author":"S Lin","year":"2023","unstructured":"Lin S, Hunt CJ, Holck J, Brask J, Krogh KBRM, Meyer AS, Wilkens C, Agger JW (2023) Fungal feruloyl esterases can catalyze release of diferulic acids from complex arabinoxylan. Int J Biol Macromol 232:123365. https:\/\/doi.org\/10.1016\/j.ijbiomac.2023.123365","journal-title":"Int J Biol Macromol"},{"issue":"30","key":"13756_CR12","doi-asserted-by":"publisher","first-page":"7916","DOI":"10.1021\/acs.jafc.0c03048","volume":"68","author":"J Liu","year":"2020","unstructured":"Liu J, Jiang Y, Chen J, Yang J, Jiang W, Zhuang W, Ying H, Yang S (2020) Metabolic engineering and adaptive evolution of Clostridium beijerinckii to increase solvent production from corn stover hydrolysate. J Agric Food Chem 68(30):7916\u20137925. https:\/\/doi.org\/10.1021\/acs.jafc.0c03048","journal-title":"J Agric Food Chem"},{"key":"13756_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2019.136399","volume":"710","author":"H Luo","year":"2020","unstructured":"Luo H, Zheng P, Bilal M, Xie F, Zeng Q, Zhu C, Yang R, Wang Z (2020) Efficient bio-butanol production from lignocellulosic waste by elucidating the mechanisms of Clostridium acetobutylicum response to phenolic inhibitors. Sci Total Environ 710:136399. https:\/\/doi.org\/10.1016\/j.scitotenv.2019.136399","journal-title":"Sci Total Environ"},{"issue":"8","key":"13756_CR14","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1107\/s0907444906019949","volume":"62","author":"W Minor","year":"2006","unstructured":"Minor W, Cymborowski M, Otwinowski Z, Chruszcz M (2006) HKL-3000: the integration of data reduction and structure solution \u2013 from diffraction images to an initial model in minutes. Acta Crystallogr Sect D Biol Crystallogr 62(8):859\u2013866. https:\/\/doi.org\/10.1107\/s0907444906019949","journal-title":"Acta Crystallogr Sect D Biol Crystallogr"},{"key":"13756_CR15","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2021.126093","volume":"343","author":"S Mondal","year":"2022","unstructured":"Mondal S, Santra S, Rakshit S, Kumar Halder S, Hossain M, Chandra Mondal K (2022) Saccharification of lignocellulosic biomass using an enzymatic cocktail of fungal origin and successive production of butanol by Clostridium acetobutylicum. Bioresour Technol 343:126093. https:\/\/doi.org\/10.1016\/j.biortech.2021.126093","journal-title":"Bioresour Technol"},{"issue":"14","key":"13756_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2023.168018","volume":"435","author":"N Oberg","year":"2023","unstructured":"Oberg N, Zallot R, Gerlt JA (2023) EFI-EST, EFI-GNT, and EFI-CGFP: enzyme function initiative (EFI) web resource for genomic enzymology tools. J Mol Biol 435(14):168018. https:\/\/doi.org\/10.1016\/j.jmb.2023.168018","journal-title":"J Mol Biol"},{"issue":"1","key":"13756_CR17","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-025-13428-y","volume":"109","author":"K Oehlenschl\u00e4ger","year":"2025","unstructured":"Oehlenschl\u00e4ger K, Hengsbach J-N, Volkmar M, Ulber R (2025) From pre-culture to solvent: current trends in Clostridium acetobutylicum cultivation. Appl Microbiol Biotechnol 109(1):47. https:\/\/doi.org\/10.1007\/s00253-025-13428-y","journal-title":"Appl Microbiol Biotechnol"},{"key":"13756_CR18","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.biortech.2019.01.064","volume":"278","author":"DM Oliveira","year":"2019","unstructured":"Oliveira DM, Mota TR, Oliva B, Segato F, Marchiosi R, Ferrarese-Filho O, Faulds CB, dos Santos WD (2019) Feruloyl esterases: biocatalysts to overcome biomass recalcitrance and for the production of bioactive compounds. Bioresour Technol 278:408\u2013423. https:\/\/doi.org\/10.1016\/j.biortech.2019.01.064","journal-title":"Bioresour Technol"},{"issue":"1","key":"13756_CR19","doi-asserted-by":"publisher","DOI":"10.1038\/s42004-023-00998-z","volume":"6","author":"P Perez-Garcia","year":"2023","unstructured":"Perez-Garcia P, Chow J, Costanzi E, Gurschke M, Dittrich J, Dierkes RF, Molitor R, Applegate V, Feuerriegel G, Tete P, Danso D, Thies S, Schumacher J, Pfleger C, Jaeger K-E, Gohlke H, Smits SHJ, Schmitz RA, Streit WR (2023) An archaeal lid-containing feruloyl esterase degrades polyethylene terephthalate. Commun Chem 6(1):193. https:\/\/doi.org\/10.1038\/s42004-023-00998-z","journal-title":"Commun Chem"},{"issue":"9","key":"13756_CR20","doi-asserted-by":"publisher","first-page":"3831","DOI":"10.1021\/acssuschemeng.3c08222","volume":"12","author":"A Phienluphon","year":"2024","unstructured":"Phienluphon A, Kondo K, Mikami B, Teo KSK, Saito K, Watanabe T, Nagata T, Katahira M (2024) Structure-based characterization and improvement of an enzymatic activity of Acremonium alcalophilum feruloyl esterase. ACS Sustainable Chem Eng 12(9):3831\u20133840. https:\/\/doi.org\/10.1021\/acssuschemeng.3c08222","journal-title":"ACS Sustainable Chem Eng"},{"issue":"W1","key":"13756_CR21","doi-asserted-by":"publisher","first-page":"W320","DOI":"10.1093\/nar\/gku316","volume":"42","author":"X Robert","year":"2014","unstructured":"Robert X, Gouet P (2014) Deciphering key features in protein structures with the new ENDscript server. Nucleic Acids Res 42(W1):W320\u2013W324. https:\/\/doi.org\/10.1093\/nar\/gku316","journal-title":"Nucleic Acids Res"},{"issue":"23","key":"13756_CR22","doi-asserted-by":"publisher","DOI":"10.3390\/ijms242317071","volume":"24","author":"G Rodr\u00edguez-Alonso","year":"2023","unstructured":"Rodr\u00edguez-Alonso G, Toledo-Marcos J, Serrano-Aguirre L, Rumayor C, Pasero B, Flores A, Saborido A, Hoyos P, Hern\u00e1iz MJ, de la Mata I, Arroyo M (2023) A novel lipase from Streptomyces exfoliatus DSMZ 41693 for biotechnological applications. Int J Mol Sci 24(23):17071. https:\/\/doi.org\/10.3390\/ijms242317071","journal-title":"Int J Mol Sci"},{"key":"13756_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2024.131854","volume":"418","author":"Q Shi","year":"2025","unstructured":"Shi Q, Ma J, Abdel-Hamid AM, Li Y, Zhong P, Wang D, Sun Z, Tu T, Zhu W, Cheng Y, Cann I (2025) Mining of latent feruloyl esterase resources in rumen and insight into dual-functional feruloyl esterase-xylanase from Pecoramyces ruminantium F1. Bioresour Technol 418:131854. https:\/\/doi.org\/10.1016\/j.biortech.2024.131854","journal-title":"Bioresour Technol"},{"key":"13756_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2023.130228","volume":"394","author":"AR Suresh","year":"2024","unstructured":"Suresh AR, Alphonse mani AS, Muthuvelu KS (2024) Investigation of pre-treatment techniques on spent substrate of Pleurotus ostreatus for enhanced biobutanol production using Clostridium acetobutylicum MTCC 11274. Bioresour Technol 394:130228. https:\/\/doi.org\/10.1016\/j.biortech.2023.130228","journal-title":"Bioresour Technol"},{"issue":"3","key":"13756_CR25","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1021\/acssuschemeng.0c06584","volume":"9","author":"SA Survase","year":"2020","unstructured":"Survase SA, Nimbalkar P, Jurgens G, Granstr\u00f6m T, Chavan P, Bankar SB (2020) Efficient strategy to alleviate the inhibitory effect of lignin-derived compounds for enhanced butanol production. ACS Sustain Chem Eng 9(3):1172\u20131179. https:\/\/doi.org\/10.1021\/acssuschemeng.0c06584","journal-title":"ACS Sustain Chem Eng"},{"key":"13756_CR26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2025.143691","volume":"311","author":"S Usman","year":"2025","unstructured":"Usman S, Zhang Y, Yang X, Guo X, Shen Y (2025) Lignocellulose degradation, enzymatic saccharification and bioethanol production from whole-crop sweet sorghum silage inoculated with feruloyl-esterase producing lactic acid bacteria. Int J Biol Macromol 311:143691. https:\/\/doi.org\/10.1016\/j.ijbiomac.2025.143691","journal-title":"Int J Biol Macromol"},{"issue":"14","key":"13756_CR27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2023.168141","volume":"435","author":"S Wang","year":"2023","unstructured":"Wang S, Xie J, Pei J, Lai L (2023) CavityPlus 2022 update: an integrated platform for comprehensive protein cavity detection and property analyses with user-friendly tools and cavity databases. J Mol Biol 435(14):168141. https:\/\/doi.org\/10.1016\/j.jmb.2023.168141","journal-title":"J Mol Biol"},{"issue":"42","key":"13756_CR28","doi-asserted-by":"publisher","first-page":"23554","DOI":"10.1021\/acs.jafc.4c06286","volume":"72","author":"Y Wang","year":"2024","unstructured":"Wang Y, Du G, Zhang Y, Yu H, Liu S, Wang Z, Ma X, Wei X, Wen B, Li Z, Fan S, Xin F (2024) Distinct adjacent substrate binding pocket regulates the activity of a decameric feruloyl esterase from Bacteroides thetaiotaomicron. J Agric Food Chem 72(42):23554\u201323566. https:\/\/doi.org\/10.1021\/acs.jafc.4c06286","journal-title":"J Agric Food Chem"},{"issue":"W1","key":"13756_CR29","doi-asserted-by":"publisher","first-page":"W296","DOI":"10.1093\/nar\/gky427","volume":"46","author":"A Waterhouse","year":"2018","unstructured":"Waterhouse A, Bertoni M, Bienert S, Studer G, Tauriello G, Gumienny R, Heer FT, de Beer TP, Rempfer C, Bordoli L, Lepore R, Schwede T (2018) SWISS-MODEL: homology modelling of protein structures and complexes. Nucleic Acids Res 46(W1):W296\u2013W303. https:\/\/doi.org\/10.1093\/nar\/gky427","journal-title":"Nucleic Acids Res"},{"issue":"20","key":"13756_CR30","doi-asserted-by":"publisher","first-page":"8449","DOI":"10.1007\/s00253-019-10102-y","volume":"103","author":"DWS Wong","year":"2019","unstructured":"Wong DWS, Chan VJ, Liao H (2019) Metagenomic discovery of feruloyl esterases from rumen microflora. Appl Microbiol Biotechnol 103(20):8449\u20138457. https:\/\/doi.org\/10.1007\/s00253-019-10102-y","journal-title":"Appl Microbiol Biotechnol"},{"key":"13756_CR31","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2022.139267","volume":"452","author":"Y Wu","year":"2023","unstructured":"Wu Y, Wen J, Su C, Jiang C, Zhang C, Wang Y, Jiang Y, Ren W, Qin P, Cai D (2023) Inhibitions of microbial fermentation by residual reductive lignin oil: concerns on the bioconversion of reductive catalytic fractionated carbohydrate pulp. Chem Eng J 452:139267. https:\/\/doi.org\/10.1016\/j.cej.2022.139267","journal-title":"Chem Eng J"},{"key":"13756_CR32","doi-asserted-by":"publisher","DOI":"10.1007\/s11705-025-2568-8","author":"Z Wu","year":"2025","unstructured":"Wu Z, Ma M, Zeng B, Wang K, Tan T (2025) Progress in one-carbon metabolism: Clostridium in green biomanufacturing. Front Chem Sci Eng. https:\/\/doi.org\/10.1007\/s11705-025-2568-8","journal-title":"Front Chem Sci Eng"},{"issue":"W1","key":"13756_CR33","doi-asserted-by":"publisher","first-page":"W374","DOI":"10.1093\/nar\/gky380","volume":"46","author":"Y Xu","year":"2018","unstructured":"Xu Y, Wang S, Hu Q, Gao S, Ma X, Zhang W, Shen Y, Chen F, Lai L, Pei J (2018) Cavityplus: a web server for protein cavity detection with pharmacophore modelling, allosteric site identification and covalent ligand binding ability prediction. Nucleic Acids Res 46(W1):W374\u2013W379. https:\/\/doi.org\/10.1093\/nar\/gky380","journal-title":"Nucleic Acids Res"},{"issue":"10","key":"13756_CR34","doi-asserted-by":"publisher","first-page":"2527","DOI":"10.1111\/febs.17420","volume":"292","author":"C Yamada","year":"2025","unstructured":"Yamada C, Kato T, Shiono Y, Koseki T, Fushinobu S (2025) Identification and structural characterization of a novel acetyl xylan esterase from Aspergillus oryzae. FEBS J 292(10):2527\u20132544. https:\/\/doi.org\/10.1111\/febs.17420","journal-title":"FEBS J"},{"key":"13756_CR35","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.bbrc.2022.02.074","volume":"600","author":"W Yang","year":"2022","unstructured":"Yang W, Sun L, Dong P, Chen Y, Zhang H, Huang X, Wu L, Chen L, Jing D, Wu Y (2022) Structure-guided rational design of the Geobacillus thermoglucosidasius feruloyl esterase GthFAE to improve its thermostability. Biochem Biophys Res Commun 600:117\u2013122. https:\/\/doi.org\/10.1016\/j.bbrc.2022.02.074","journal-title":"Biochem Biophys Res Commun"},{"issue":"1","key":"13756_CR36","doi-asserted-by":"publisher","DOI":"10.3390\/catal15010092","volume":"15","author":"S Yang","year":"2025","unstructured":"Yang S, Lin M, Chen J, Liu M, Chen Q (2025) Engineering of an alkaline feruloyl esterase PhFAE for enhanced thermal stability and catalytic efficiency through molecular dynamics and FireProt. Catalysts 15(1):92. https:\/\/doi.org\/10.3390\/catal15010092","journal-title":"Catalysts"}],"container-title":["Applied Microbiology and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00253-026-13756-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00253-026-13756-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00253-026-13756-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T03:11:47Z","timestamp":1772680307000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00253-026-13756-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,4]]},"references-count":36,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["13756"],"URL":"https:\/\/doi.org\/10.1007\/s00253-026-13756-7","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-7712209\/v1","asserted-by":"object"}]},"ISSN":["1432-0614"],"issn-type":[{"value":"1432-0614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,4]]},"assertion":[{"value":"25 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 January 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 February 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 March 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"91"}}