{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T23:09:30Z","timestamp":1780614570184,"version":"3.54.1"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:00:00Z","timestamp":1780617600000},"content-version":"vor","delay-in-days":44,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Appl Microbiol Biotechnol"],"DOI":"10.1007\/s00253-026-13826-w","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T21:16:41Z","timestamp":1776892601000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Leaf mold extract agar facilitates recovery of soil bacterial diversity beyond Bacillus\u00a0dominance"],"prefix":"10.1007","volume":"110","author":[{"given":"Fumiaki","family":"Tabuchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhiro","family":"Mikami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Ishii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyunichiro","family":"Yasukawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanobu","family":"Miyauchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. P. N.","family":"De Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Miyashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,22]]},"reference":[{"issue":"4","key":"13826_CR1","doi-asserted-by":"publisher","first-page":"1830","DOI":"10.1128\/AEM.67.4.1830-1838.2001","volume":"67","author":"L Ald\u00e9n","year":"2001","unstructured":"Ald\u00e9n L, Demoling F, B\u00e5\u00e5th E (2001) Rapid method of determining factors limiting bacterial growth in soil. Appl Environ Microbiol 67(4):1830\u20131838. https:\/\/doi.org\/10.1128\/AEM.67.4.1830-1838.2001","journal-title":"Appl Environ Microbiol"},{"issue":"11","key":"13826_CR2","doi-asserted-by":"publisher","first-page":"3826","DOI":"10.1128\/AEM.02542-08","volume":"75","author":"Y Aoi","year":"2009","unstructured":"Aoi Y, Kinoshita T, Hata T, Ohta H, Obokata H, Tsuneda S (2009) Hollow-fiber membrane chamber as a device for in situ environmental cultivation. Appl Environ Microbiol 75(11):3826\u20133833. https:\/\/doi.org\/10.1128\/AEM.02542-08","journal-title":"Appl Environ Microbiol"},{"issue":"6","key":"13826_CR3","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1002\/bit.260110607","volume":"11","author":"F Arcamone","year":"1969","unstructured":"Arcamone F, Cassinelli G, Fantini G, Grein A, Orezzi P, Pol C, Spalla C (1969) Adriamycin, 14\u2010hydroxydaimomycin, a new antitumor antibiotic from S. peucetius var. caesius. Biotechnol Bioeng 11(6):1101\u20131110. https:\/\/doi.org\/10.1002\/bit.260110607","journal-title":"Biotechnol Bioeng"},{"issue":"1","key":"13826_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1099\/00221287-144-1-1","volume":"144","author":"SF Bloomfield","year":"1998","unstructured":"Bloomfield SF, Stewart G, Dodd CER, Booth IR, Power EGM (1998) The viable but non-culturable phenomenon explained? Microbiology (Reading) 144(1):1\u20133. https:\/\/doi.org\/10.1099\/00221287-144-1-1","journal-title":"Microbiology (Reading)"},{"key":"13826_CR5","doi-asserted-by":"publisher","DOI":"10.3390\/jof3020027","author":"AM Borman","year":"2017","unstructured":"Borman AM, Fraser M, Palmer MD, Szekely A, Houldsworth M, Patterson Z, Johnson EM (2017) MIC distributions and evaluation of fungicidal activity for amphotericin B, itraconazole, voriconazole, posaconazole and caspofungin and 20 species of pathogenic filamentous fungi determined using the CLSI broth microdilution method. J Fungi (Basel). https:\/\/doi.org\/10.3390\/jof3020027","journal-title":"J Fungi (Basel)"},{"issue":"3","key":"13826_CR6","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1128\/AAC.15.3.361","volume":"15","author":"RW Burg","year":"1979","unstructured":"Burg RW, Miller BM, Baker EE, Birnbaum J, Currie SA, Hartman R, Kong YL, Monaghan RL, Olson G, Putter I, Tunac JB, Wallick H, Stapley EO, Oiwa R, Omura S (1979) Avermectins, new family of potent anthelmintic agents: producing organism and fermentation. Antimicrob Agents Chemother 15(3):361\u2013367. https:\/\/doi.org\/10.1128\/AAC.15.3.361","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"13826_CR7","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1111\/myc.12228","volume":"57","author":"S Dolatabadi","year":"2014","unstructured":"Dolatabadi S, de Hoog GS, Meis JF, Walther G (2014) Species boundaries and nomenclature of Rhizopus arrhizus (syn. R. oryzae). Mycoses 57(3):108\u2013127. https:\/\/doi.org\/10.1111\/myc.12228","journal-title":"Mycoses"},{"issue":"8","key":"13826_CR8","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1038\/nprot.2008.102","volume":"3","author":"BC Ferrari","year":"2008","unstructured":"Ferrari BC, Winsley T, Gillings M, Binnerup S (2008) Cultivating previously uncultured soil bacteria using a soil substrate membrane system. Nat Protoc 3(8):1261\u20131269. https:\/\/doi.org\/10.1038\/nprot.2008.102","journal-title":"Nat Protoc"},{"issue":"5739","key":"13826_CR9","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1126\/science.1112665","volume":"309","author":"J Gans","year":"2005","unstructured":"Gans J, Wolinsky M, Dunbar J (2005) Computational improvements reveal great bacterial diversity and high metal toxicity in soil. Science 309(5739):1387\u20131390. https:\/\/doi.org\/10.1126\/science.1112665","journal-title":"Science"},{"issue":"2","key":"13826_CR10","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1039\/d1lc00723h","volume":"22","author":"CBS Goh","year":"2022","unstructured":"Goh CBS, Goh CHP, Wong LW, Cheng WT, Yule CM, Ong KS, Lee SM, Pasbakhsh P, Tan JBL (2022) A three-dimensional (3D) printing approach to fabricate an isolation chip for high throughput in situ cultivation of environmental microbes. Lab Chip 22(2):387\u2013402. https:\/\/doi.org\/10.1039\/d1lc00723h","journal-title":"Lab Chip"},{"issue":"3","key":"13826_CR11","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1128\/aac.48.3.774-779.2004","volume":"48","author":"H Hamamoto","year":"2004","unstructured":"Hamamoto H, Kurokawa K, Kaito C, Kamura K, Manitra Razanajatovo I, Kusuhara H, Santa T, Sekimizu K (2004) Quantitative evaluation of the therapeutic effects of antibiotics using silkworms infected with human pathogenic microorganisms. Antimicrob Agents Chemother 48(3):774\u2013779. https:\/\/doi.org\/10.1128\/aac.48.3.774-779.2004","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"13826_CR12","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-26702-0","volume":"12","author":"H Hamamoto","year":"2021","unstructured":"Hamamoto H, Panthee S, Paudel A, Ishii K, Yasukawa J, Su J, Miyashita A, Itoh H, Tokumoto K, Inoue M, Sekimizu K (2021) Serum apolipoprotein A-I potentiates the therapeutic efficacy of lysocin E against Staphylococcus aureus. Nat Commun 12(1):6364. https:\/\/doi.org\/10.1038\/s41467-021-26702-0","journal-title":"Nat Commun"},{"issue":"2","key":"13826_CR13","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1038\/nchembio.1710","volume":"11","author":"H Hamamoto","year":"2015","unstructured":"Hamamoto H, Urai M, Ishii K, Yasukawa J, Paudel A, Murai M, Kaji T, Kuranaga T, Hamase K, Katsu T, Su J, Adachi T, Uchida R, Tomoda H, Yamada M, Souma M, Kurihara H, Inoue M, Sekimizu K (2015) Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane. Nat Chem Biol 11(2):127\u2013133. https:\/\/doi.org\/10.1038\/nchembio.1710","journal-title":"Nat Chem Biol"},{"issue":"9","key":"13826_CR14","first-page":"350","volume":"2","author":"D Harwani","year":"2013","unstructured":"Harwani D (2013) The great plate count anomaly and the unculturable bacteria. Microbiology 2(9):350\u2013351","journal-title":"Microbiology"},{"issue":"5","key":"13826_CR15","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/0385-6380(87)90108-7","volume":"65","author":"M Hayakawa","year":"1987","unstructured":"Hayakawa M, Nonomura H (1987) Humic acid-vitamin agar, a new medium for the selective isolation of soil actinomycetes. J Ferment Technol 65(5):501\u2013509. https:\/\/doi.org\/10.1016\/0385-6380(87)90108-7","journal-title":"J Ferment Technol"},{"issue":"5","key":"13826_CR16","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.02450-22","volume":"10","author":"M Hazu","year":"2022","unstructured":"Hazu M, Ahmed A, Curry E, Hornby DP, Gjerde DT (2022) Cell chromatography: biocompatible chromatographic separation and interrogation of microbial cells. Microbiol Spectr 10(5):e0245022. https:\/\/doi.org\/10.1128\/spectrum.02450-22","journal-title":"Microbiol Spectr"},{"issue":"4","key":"13826_CR17","doi-asserted-by":"publisher","DOI":"10.1128\/mSystems.00748-21","volume":"6","author":"YN Ho","year":"2021","unstructured":"Ho YN, Chen YL, Liu DY (2021) Portable and rapid sequencing device with microbial community-guided culture strategies for precious field and environmental samples. mSystems 6(4):e0074821. https:\/\/doi.org\/10.1128\/mSystems.00748-21","journal-title":"mSystems"},{"issue":"9","key":"13826_CR18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0333476","volume":"20","author":"M Ishii","year":"2025","unstructured":"Ishii M, Mikami K, Tabuchi F, Maruyama N, Miyashita A (2025) A human-relevant alternative infection model for mucormycosis using the silkworm Bombyx mori. PLoS One 20(9):e0333476. https:\/\/doi.org\/10.1371\/journal.pone.0333476","journal-title":"PLoS One"},{"issue":"5","key":"13826_CR19","doi-asserted-by":"publisher","first-page":"2391","DOI":"10.1128\/AEM.68.5.2391-2396.2002","volume":"68","author":"PH Janssen","year":"2002","unstructured":"Janssen PH, Yates PS, Grinton BE, Taylor PM, Sait M (2002) Improved culturability of soil bacteria and isolation in pure culture of novel members of the divisions Acidobacteria, Actinobacteria, Proteobacteria, and Verrucomicrobia. Appl Environ Microbiol 68(5):2391\u20132396. https:\/\/doi.org\/10.1128\/AEM.68.5.2391-2396.2002","journal-title":"Appl Environ Microbiol"},{"issue":"5570","key":"13826_CR20","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1126\/science.1070633","volume":"296","author":"T Kaeberlein","year":"2002","unstructured":"Kaeberlein T, Lewis K, Epstein SS (2002) Isolating \u201cuncultivable\u201d microorganisms in pure culture in a simulated natural environment. Science 296(5570):1127\u20131129. https:\/\/doi.org\/10.1126\/science.1070633","journal-title":"Science"},{"issue":"4","key":"13826_CR21","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1006\/mpat.2002.0494","volume":"32","author":"C Kaito","year":"2002","unstructured":"Kaito C, Akimitsu N, Watanabe H, Sekimizu K (2002) Silkworm larvae as an animal model of bacterial infection pathogenic to humans. Microb Pathog 32(4):183\u2013190. https:\/\/doi.org\/10.1006\/mpat.2002.0494","journal-title":"Microb Pathog"},{"issue":"19","key":"13826_CR22","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00807-18","volume":"84","author":"S Kato","year":"2018","unstructured":"Kato S, Yamagishi A, Daimon S, Kawasaki K, Tamaki H, Kitagawa W, Abe A, Tanaka M, Sone T, Asano K, Kamagata Y (2018) Isolation of previously uncultured slow-growing bacteria by using a simple modification in the preparation of agar media. Appl Environ Microbiol 84(19):e00807-18. https:\/\/doi.org\/10.1128\/AEM.00807-18","journal-title":"Appl Environ Microbiol"},{"issue":"4","key":"13826_CR23","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.1007\/s00284-021-02397-w","volume":"78","author":"E Khoury","year":"2021","unstructured":"Khoury E, Abou Fayad A, Karam Sarkis D, Fahs H, Gunsalus KC, Kallassy Awad M (2021) The microbiome of the Lebanese Wild Apple, Malus trilobata, is a rich source of potential biocontrol agents for fungal post-harvest pathogens of apples. Curr Microbiol 78(4):1388\u20131398. https:\/\/doi.org\/10.1007\/s00284-021-02397-w","journal-title":"Curr Microbiol"},{"issue":"9","key":"13826_CR24","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.7164\/antibiotics.40.1249","volume":"40","author":"T Kino","year":"1987","unstructured":"Kino T, Hatanaka H, Hashimoto M, Nishiyama M, Goto T, Okuhara M, Kohsaka M, Aoki H, Imanaka H (1987) FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. J Antibiot (Tokyo) 40(9):1249\u20131255. https:\/\/doi.org\/10.7164\/antibiotics.40.1249","journal-title":"J Antibiot (Tokyo)"},{"issue":"7535","key":"13826_CR25","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1038\/nature14098","volume":"517","author":"LL Ling","year":"2015","unstructured":"Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, Mueller A, Sch\u00e4berle TF, Hughes DE, Epstein S, Jones M, Lazarides L, Steadman VA, Cohen DR, Felix CR, Fetterman KA, Millett WP, Nitti AG, Zullo AM, Chen C, Lewis K (2015) A new antibiotic kills pathogens without detectable resistance. Nature 517(7535):455\u2013459. https:\/\/doi.org\/10.1038\/nature14098","journal-title":"Nature"},{"issue":"3","key":"13826_CR26","doi-asserted-by":"publisher","first-page":"139","DOI":"10.5582\/ddt.2021.01041","volume":"15","author":"A Miyashita","year":"2021","unstructured":"Miyashita A, Hamamoto H, Sekimizu K (2021) Applying the silkworm model for the search of immunosuppressants. Drug Discoveries & Therapeutics 15(3):139\u2013142. https:\/\/doi.org\/10.5582\/ddt.2021.01041","journal-title":"Drug Discoveries & Therapeutics"},{"key":"13826_CR27","doi-asserted-by":"publisher","DOI":"10.5582\/ddt.2015.01000","author":"A Miyashita","year":"2015","unstructured":"Miyashita A, Hirai Y, Sekimizu K, Kaito C (2015a) Antibiotic-producing bacteria from stag beetle mycangia. Drug Discoveries & Therapeutics. https:\/\/doi.org\/10.5582\/ddt.2015.01000","journal-title":"Drug Discoveries & Therapeutics"},{"issue":"1","key":"13826_CR28","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1111\/j.1574-6968.2012.02599.x","volume":"333","author":"A Miyashita","year":"2012","unstructured":"Miyashita A, Iyoda S, Ishii K, Hamamoto H, Sekimizu K, Kaito C (2012) Lipopolysaccharide O-antigen of enterohemorrhagic Escherichia coli O157:H7 is required for killing both insects and mammals. FEMS Microbiol Lett 333(1):59\u201368. https:\/\/doi.org\/10.1111\/j.1574-6968.2012.02599.x","journal-title":"FEMS Microbiol Lett"},{"key":"13826_CR29","doi-asserted-by":"publisher","DOI":"10.3389\/frfst.2023.1012121","author":"A Miyashita","year":"2023","unstructured":"Miyashita A, Kataoka K, Tsuchida T, Ogasawara AA, Nakajima H, Takahashi M, Sekimizu K (2023) High molecular weight glucose homopolymer of broccoli (Brassica oleracea var. italica) stimulates both invertebrate and mammalian immune systems. Front Food Sci Technol. https:\/\/doi.org\/10.3389\/frfst.2023.1012121","journal-title":"Front Food Sci Technol"},{"issue":"20","key":"13826_CR30","doi-asserted-by":"publisher","first-page":"14412","DOI":"10.1074\/jbc.M113.525139","volume":"289","author":"A Miyashita","year":"2014","unstructured":"Miyashita A, Kizaki H, Kawasaki K, Sekimizu K, Kaito C (2014) Primed Immune Responses to Gram-negative Peptidoglycans Confer Infection Resistance in Silkworms *. J Biol Chem 289(20):14412\u201314421. https:\/\/doi.org\/10.1074\/jbc.M113.525139","journal-title":"J Biol Chem"},{"issue":"6","key":"13826_CR31","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1242\/bio.019190","volume":"5","author":"A Miyashita","year":"2016","unstructured":"Miyashita A, Kizaki H, Sekimizu K, Kaito C (2016a) Body-enlarging effect of royal jelly in a non-holometabolous insect species, Gryllus bimaculatus. Biol Open 5(6):770\u2013776. https:\/\/doi.org\/10.1242\/bio.019190","journal-title":"Biol Open"},{"issue":"1","key":"13826_CR32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0146999","volume":"11","author":"A Miyashita","year":"2016","unstructured":"Miyashita A, Kizaki H, Sekimizu K, Kaito C (2016b) No Effect of Body Size on the Frequency of Calling and Courtship Song in the Two-Spotted Cricket, Gryllus bimaculatus. PLoS One 11(1):e0146999. https:\/\/doi.org\/10.1371\/journal.pone.0146999","journal-title":"PLoS One"},{"key":"13826_CR33","doi-asserted-by":"publisher","DOI":"10.1093\/femsmc\/xtac014","volume":"3","author":"A Miyashita","year":"2022","unstructured":"Miyashita A, Mitsutomi S, Mizushima T, Sekimizu K (2022a) Repurposing the PDMA-approved drugs in Japan using an insect model of staphylococcal infection. FEMS Microbes 3:xtac014. https:\/\/doi.org\/10.1093\/femsmc\/xtac014","journal-title":"FEMS Microbes"},{"issue":"2","key":"13826_CR34","doi-asserted-by":"publisher","first-page":"51","DOI":"10.5582\/ddt.2021.01020","volume":"15","author":"A Miyashita","year":"2021","unstructured":"Miyashita A, Sekimizu K (2021) Using silkworms to search for lactic acid bacteria that contribute to infection prevention and improvement of hyperglycemia. Drug Discov Ther 15(2):51\u201354. https:\/\/doi.org\/10.5582\/ddt.2021.01020","journal-title":"Drug Discov Ther"},{"key":"13826_CR35","doi-asserted-by":"publisher","DOI":"10.5582\/ddt.2022.01058","author":"A Miyashita","year":"2022","unstructured":"Miyashita A, Sekimizu K, Kaito C (2022b) Surrounding gas composition affects the calling song development in the two-spotted cricket (Gryllus bimaculatus). Drug Discov Ther. https:\/\/doi.org\/10.5582\/ddt.2022.01058","journal-title":"Drug Discov Ther"},{"issue":"6","key":"13826_CR36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0130486","volume":"10","author":"A Miyashita","year":"2015","unstructured":"Miyashita A, Takahashi S, Ishii K, Sekimizu K, Kaito C (2015b) Primed immune responses triggered by ingested bacteria lead to systemic infection tolerance in silkworms. PLoS ONE 10(6):e0130486. https:\/\/doi.org\/10.1371\/journal.pone.0130486","journal-title":"PLoS ONE"},{"issue":"8","key":"13826_CR37","doi-asserted-by":"publisher","first-page":"2445","DOI":"10.1128\/aem.01754-09","volume":"76","author":"D Nichols","year":"2010","unstructured":"Nichols D, Cahoon N, Trakhtenberg EM, Pham L, Mehta A, Belanger A, Kanigan T, Lewis K, Epstein SS (2010) Use of ichip for high-throughput in situ cultivation of \u201cuncultivable\u201d microbial species. Appl Environ Microbiol 76(8):2445\u20132450. https:\/\/doi.org\/10.1128\/aem.01754-09","journal-title":"Appl Environ Microbiol"},{"issue":"10","key":"13826_CR38","doi-asserted-by":"publisher","first-page":"2679","DOI":"10.1093\/jac\/dkv175","volume":"70","author":"LJ Piddock","year":"2015","unstructured":"Piddock LJ (2015) Teixobactin, the first of a new class of antibiotics discovered by iChip technology? J Antimicrob Chemother 70(10):2679\u20132680. https:\/\/doi.org\/10.1093\/jac\/dkv175","journal-title":"J Antimicrob Chemother"},{"key":"13826_CR39","doi-asserted-by":"publisher","DOI":"10.3390\/jof6040265","author":"A Skiada","year":"2020","unstructured":"Skiada A, Pavleas I, Drogari-Apiranthitou M (2020) Epidemiology and diagnosis of mucormycosis: an update. J Fungi. https:\/\/doi.org\/10.3390\/jof6040265","journal-title":"J Fungi"},{"issue":"10","key":"13826_CR40","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1010858","volume":"18","author":"C Smith","year":"2022","unstructured":"Smith C, Lee SC (2022) Current treatments against mucormycosis and future directions. PLoS Pathog 18(10):e1010858. https:\/\/doi.org\/10.1371\/journal.ppat.1010858","journal-title":"PLoS Pathog"},{"key":"13826_CR41","first-page":"152","volume":"33","author":"E Stackebrandt","year":"2006","unstructured":"Stackebrandt E, Ebers J (2006) Taxonomic parameters revisited: tarnished gold standards. Microbiol Today 33:152\u2013155","journal-title":"Microbiol Today"},{"issue":"3","key":"13826_CR42","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1128\/AAC.2.3.122","volume":"2","author":"EO Stapley","year":"1972","unstructured":"Stapley EO, Jackson M, Hernandez S, Zimmerman SB, Currie SA, Mochales S, Mata JM, Woodruff HB, Hendlin D (1972) Cephamycins, a new family of beta-lactam antibiotics. I. Production by actinomycetes, including Streptomyces lactamdurans sp. n. Antimicrob Agents Chemother 2(3):122\u2013131. https:\/\/doi.org\/10.1128\/AAC.2.3.122","journal-title":"Antimicrob Agents Chemother"},{"issue":"2","key":"13826_CR43","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1038\/s41429-024-00788-2","volume":"78","author":"F Tabuchi","year":"2025","unstructured":"Tabuchi F, Mikami K, Miyauchi M, Sekimizu K, Miyashita A (2025) Discovery of new AMR drugs targeting modulators of antimicrobial activity using in vivo silkworm screening systems. J Antibiot (Tokyo) 78(2):69\u201377. https:\/\/doi.org\/10.1038\/s41429-024-00788-2","journal-title":"J Antibiot (Tokyo)"},{"issue":"22","key":"13826_CR44","doi-asserted-by":"publisher","first-page":"4759","DOI":"10.1016\/j.atmosenv.2007.03.057","volume":"41","author":"MPM Taha","year":"2007","unstructured":"Taha MPM, Drew GH, Tamer Vestlund A, Aldred D, Longhurst PJ, Pollard SJT (2007) Enumerating actinomycetes in compost bioaerosols at source\u2014use of soil compost agar to address plate \u2018masking.\u2019 Atmos Environ 41(22):4759\u20134765. https:\/\/doi.org\/10.1016\/j.atmosenv.2007.03.057","journal-title":"Atmos Environ"},{"issue":"3","key":"13826_CR45","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1099\/ijs.0.02750-0","volume":"54","author":"Y Tanaka","year":"2004","unstructured":"Tanaka Y, Hanada S, Manome A, Tsuchida T, Kurane R, Nakamura K, Kamagata Y (2004) Catellibacterium nectariphilum gen. nov., sp. nov., which requires a diffusible compound from a strain related to the genus Sphingomonas for vigorous growth. Int J Syst Evol Microbiol 54(3):955\u2013959. https:\/\/doi.org\/10.1099\/ijs.0.02750-0","journal-title":"Int J Syst Evol Microbiol"},{"issue":"7","key":"13826_CR46","doi-asserted-by":"publisher","first-page":"674","DOI":"10.7164\/antibiotics.52.674","volume":"52","author":"M Tomishima","year":"1999","unstructured":"Tomishima M, Ohki H, Yamada A, Takasugi H, Maki K, Tawara S, Tanaka H (1999) FK463, a novel water-soluble echinocandin lipopeptide: synthesis and antifungal activity. J Antibiot (Tokyo) 52(7):674\u2013676. https:\/\/doi.org\/10.7164\/antibiotics.52.674","journal-title":"J Antibiot (Tokyo)"},{"issue":"3","key":"13826_CR47","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1111\/j.1461-0248.2007.01139.x","volume":"11","author":"MG van der Heijden","year":"2008","unstructured":"van der Heijden MG, Bardgett RD, van Straalen NM (2008) The unseen majority: soil microbes as drivers of plant diversity and productivity in terrestrial ecosystems. Ecol Lett 11(3):296\u2013310. https:\/\/doi.org\/10.1111\/j.1461-0248.2007.01139.x","journal-title":"Ecol Lett"},{"issue":"3062","key":"13826_CR48","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1126\/science.118.3062.259","volume":"118","author":"SA Waksman","year":"1953","unstructured":"Waksman SA (1953) Streptomycin: background, isolation, properties, and utilization. Science 118(3062):259\u2013266. https:\/\/doi.org\/10.1126\/science.118.3062.259","journal-title":"Science"},{"issue":"3","key":"13826_CR49","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1128\/jb.52.3.393-397.1946","volume":"52","author":"SA Waksman","year":"1946","unstructured":"Waksman SA, Reilly HC, Johnstone Donald B (1946) Isolation of streptomycin-producing strains of Streptomyces griseus. J Bacteriol 52(3):393\u2013397. https:\/\/doi.org\/10.1128\/jb.52.3.393-397.1946","journal-title":"J Bacteriol"}],"container-title":["Applied Microbiology and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00253-026-13826-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00253-026-13826-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00253-026-13826-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T22:37:18Z","timestamp":1780612638000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00253-026-13826-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,22]]},"references-count":49,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["13826"],"URL":"https:\/\/doi.org\/10.1007\/s00253-026-13826-w","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-7127727\/v1","asserted-by":"object"}]},"ISSN":["1432-0614"],"issn-type":[{"value":"1432-0614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,22]]},"assertion":[{"value":"15 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 April 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 April 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"175"}}