{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T10:24:43Z","timestamp":1791973483199,"version":"4.4.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2003,4,29]],"date-time":"2003-04-29T00:00:00Z","timestamp":1051574400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skeletal Radiol"],"published-print":{"date-parts":[[2003,6]]},"DOI":"10.1007\/s00256-003-0629-x","type":"journal-article","created":{"date-parts":[[2010,8,20]],"date-time":"2010-08-20T19:02:05Z","timestamp":1282330925000},"page":"311-327","source":"Crossref","is-referenced-by-count":224,"title":["SAPHO: syndrome or concept? Imaging findings"],"prefix":"10.1007","volume":"32","author":[{"given":"J. W. S.","family":"Earwaker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Cotten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2003,4,29]]},"reference":[{"key":"0629_CR1","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1002\/art.1780040609","volume":"4","author":"Windom","year":"1961","unstructured":"Windom RE, Sandford JP, Ziff M. Acne conglobata and arthritis. Arthritis Rheum 1961; 4:632\u2013635.","journal-title":"Arthritis Rheum"},{"key":"0629_CR2","first-page":"329","volume":"15","author":"Gideon","year":"1972","unstructured":"Gideon A, Holthusen W, Masel L. Subacute and chronic symmetrical osteomyelitis. Ann Radiol 1972; 15:329\u2013342.","journal-title":"Ann Radiol"},{"key":"0629_CR3","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0022-3476(78)80501-0","volume":"932","author":"Bjorksten","year":"1978","unstructured":"Bjorksten B, Gustavson KH, Eriksson B et al. Chronic recurrent multifocal osteomyelitis and pustulosis palmoplantaris. J Pediatr 1978; 932:227\u2013231.","journal-title":"J Pediatr"},{"key":"0629_CR4","first-page":"187","volume":"54","author":"Chamot","year":"1987","unstructured":"Chamot A, Benhamou CL, Kahn MF, et al. Le syndrome acne pustulose hyperostose osteite (SAPHO). Rev Rhum 1987; 54:187\u2013196.","journal-title":"Rev Rhum"},{"key":"0629_CR5","first-page":"109","volume":"6","author":"Benhamou","year":"1988","unstructured":"Benhamou CL, Chamot AM, Kahn MF. Synovitis-acne-pustulosis-hyperostosis osteomyelitis syndrome (SAPHO). Clin Exp Rheumatol 1988; 6:109\u2013112.","journal-title":"Clin Exp Rheumatol"},{"key":"0629_CR6","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1159\/000247336","volume":"186","author":"Grosshans","year":"1993","unstructured":"Grosshans EM. SAPHO the impossible acronym. Dermatology 1993; 186:161\u2013162.","journal-title":"Dermatology"},{"key":"0629_CR7","doi-asserted-by":"crossref","first-page":"585","DOI":"10.2214\/ajr.170.3.9490935","volume":"170","author":"Boutin","year":"1988","unstructured":"Boutin RD, Resnick D. The SAPHO syndrome: an evolving concept for unifying several idiopathic disorders of bone and skin. AJR Am J Roentgenol 1988; 170:585\u2013591.","journal-title":"AJR Am J Roentgenol"},{"key":"0629_CR8","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s003300050476","volume":"8","author":"Freyschmidt","year":"1998","unstructured":"Freyschmidt J, Sternberg A. The bull's head sign: scintigraphy pattern of sternoclavicular hyperostosis and pustulotic arthrosclerosis. Eur Radiol 1998; 8:807\u2013812.","journal-title":"Eur Radiol"},{"key":"0629_CR9","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1148\/radiology.191.1.8134572","volume":"191","author":"Kasperzyk","year":"1994","unstructured":"Kasperzyk A, Freyschmidt J. Pustolotic arthro-osteitis: spectrum of bone lesions with palmoplantar pustulosis. Radiology 1994; 191:207\u2013211.","journal-title":"Radiology"},{"key":"0629_CR10","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1007\/s003300050475","volume":"8","author":"Sugimoto","year":"1998","unstructured":"Sugimoto H, Tamura K, Fujii T. The SAPHO syndrome: defining the radiological spectrum of disease comprising the syndrome. Eur Radiol 1998; 8:800\u2013806.","journal-title":"Eur Radiol"},{"key":"0629_CR11","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0049-0172(99)80027-4","volume":"293","author":"Hayem","year":"1999","unstructured":"Hayem G, Bouchaud-Chabot A, Benali K, et al. SAPHO syndrome: a long term follow up study of 120 cases. Semin Arthritis Rheum 1999; 293:159\u2013171.","journal-title":"Semin Arthritis Rheum"},{"key":"0629_CR12","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/BF00191670","volume":"19","author":"Jurik","year":"1990","unstructured":"Jurik AG. Anterior chest wall involvement in patients with pustulosis palmoplantaris. Skeletal Radiol 1990; 19:271\u2013277.","journal-title":"Skeletal Radiol"},{"key":"0629_CR13","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1097\/00000478-199611000-00008","volume":"20","author":"Reith","year":"1996","unstructured":"Reith JD, Bauer TW, Schils JP. Osseous manifestations of SAPHO (synovitis, acne, pustulosis, hyperostosis, osteitis) syndrome. Am J Surg Pathol 1996; 20:1368\u20131377.","journal-title":"Am J Surg Pathol"},{"key":"0629_CR14","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1053\/sarh.2000.8371","volume":"30","author":"Van","year":"2000","unstructured":"Van Doornum S, Barraclough D, McColl G, Wicks I. SAPHO: Rare or just not recognised? Semin Arthritis Rheum 2000; 30:70\u201377.","journal-title":"Semin Arthritis Rheum"},{"key":"0629_CR15","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s002560050493","volume":"28","author":"Davies","year":"1999","unstructured":"Davies AM, Marins AJ, Evans N, et al. SAPHO syndrome: 20\u00a0year follow up. Skeletal Radiol 1999; 28:159\u2013162.","journal-title":"Skeletal Radiol"},{"key":"0629_CR16","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0950-3579(94)80022-7","volume":"8","author":"Kahn","year":"1994","unstructured":"Kahn MF, Khan MA. The SAPHO syndrome. Baillieres Clin Rheumatol 1994; 8:333\u2013362.","journal-title":"Baillieres Clin Rheumatol"},{"key":"0629_CR17","first-page":"2135","volume":"22","author":"Maugars","year":"1995","unstructured":"Maugars Y, Berthelot JM, Ducloux JM, Prost A. SAPHO syndrome. a follow up study of 19 cases with special emphasis on enthesis involvement. J Rheumatol 1995; 22:2135\u20132141.","journal-title":"J Rheumatol"},{"key":"0629_CR18","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/s002560050227","volume":"26","author":"Jurik","year":"1997","unstructured":"Jurik AG, Egund N. MRI in chronic recurrent multifocal osteomyelitis. Skeletal Radiol 1997; 26:230\u2013238.","journal-title":"Skeletal Radiol"},{"key":"0629_CR19","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1093\/rheumatology\/32.5.403","volume":"32","author":"Watts","year":"1993","unstructured":"Watts RA, Crisp AJ, Hazleman BL, et al. Arthro-osteitis: a clinical spectrum. Br J Rheum 1993; 32:403\u2013407.","journal-title":"Br J Rheum"},{"key":"0629_CR20","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s002560050494","volume":"28","author":"Nachtigal","year":"1999","unstructured":"Nachtigal A, Cardinal E, Bureau NJ, et al. Vertebral involvement in SAPHO syndrome: MRI findings. Skeletal Radiol 1999; 28:163\u2013168.","journal-title":"Skeletal Radiol"},{"key":"0629_CR21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00366761","volume":"18","author":"Van","year":"1989","unstructured":"Van Holsbeeck M, Martel W, Dequeker J, et al. Soft tissue involvement, mediastinal pseudotumour, and venous thrombosis in pustulotic arthro-osteitis. Skeletal Radiol 1989; 18:1\u20138.","journal-title":"Skeletal Radiol"},{"key":"0629_CR22","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1136\/ard.56.1.52","volume":"56","author":"Toussirot","year":"1997","unstructured":"Toussirot E, Dupond JL, Wendling D. Spondylodiscitis in SAPHO syndrome. A series of eight cases. Ann Rheum Dis 1997; 56:52\u201358.","journal-title":"Ann Rheum Dis"},{"key":"0629_CR23","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/BF00379164","volume":"95","author":"Sonozaki","year":"1979","unstructured":"Sonozaki H, Azuma O, Okai K, et al. Clinical features of 22 cases with \"inter-sterno-costo-clavicular \" ossification. A new rheumatic syndrome. Arch Orthop Trauma Surg 1979; 95:13\u201322.","journal-title":"Arch Orthop Trauma Surg"},{"key":"0629_CR24","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1148\/radiology.162.2.2948214","volume":"162","author":"Ellis","year":"1987","unstructured":"Ellis BI, Shier CK, Leisen JC, et al. Acne-associated spondyloarthropathy: radiographic features. Radiology 1987; 162:541\u2013545.","journal-title":"Radiology"},{"key":"0629_CR25","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1111\/j.1600-0714.1999.tb02106.x","volume":"28","author":"Eyrich","year":"1999","unstructured":"Eyrich GKH, Harder C, Sailer HF, et al. Primary chronic osteomyelitis associated with synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO syndrome). J Oral Pathol Med 1999; 28:456\u2013464.","journal-title":"J Oral Pathol Med"},{"key":"0629_CR26","first-page":"345","volume":"69","author":"Huaux","year":"1986","unstructured":"Huaux JP, Maldague B. Malghem J, et al. Pustulotic arthro-osteitis and related disorders in children and adults. JBR-BTR 1986; 69:345\u2013354.","journal-title":"BTR"},{"key":"0629_CR27","doi-asserted-by":"crossref","first-page":"520","DOI":"10.7326\/0003-4819-97-4-520","volume":"97","author":"Rosner","year":"1982","unstructured":"Rosner IA, Richter DE, Huettner TL, et al. Spondyloarthropathy associated with hidradenitis suppurativa and acne conglobata. Ann Intern Med 1982; 97:520\u2013525.","journal-title":"Ann Intern Med"},{"key":"0629_CR28","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1148\/radiographics.15.5.7501856","volume":"15","author":"Cotten","year":"1995","unstructured":"Cotten A. Flipo RM, Mentre A, et al. SAPHO syndrome. Radiographics 1995; 15:1147\u20131154.","journal-title":"Radiographics"},{"key":"0629_CR29","first-page":"289","volume":"169","author":"Hatem","year":"1997","unstructured":"Hatem SF, et al. Case 3: Chronic recurrent multifocal osteomyelitis (CRMO). AJR Roentgen 01 1997; 169:285; 289\u2013291.","journal-title":"AJR Am J Roentgenol"},{"key":"0629_CR30","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1136\/ard.55.11.789","volume":"55","author":"Tyrrell","year":"1996","unstructured":"Tyrrell PNM, Cassar-Pullicino VN, Eisenstein JF, et al. Back pain in childhood. Ann Rheum Dis 1996; 55:789\u2013793.","journal-title":"Ann Rheum Dis"},{"key":"0629_CR31","doi-asserted-by":"crossref","unstructured":"Anderson S, et al. Imaging of chronic recurrent multifocal osteomyelitis of childhood first presenting with isolated primary spinal involvement. Skeletal Radiol DOI 10.1007\/s00256-002-0602-0","DOI":"10.1007\/s00256-002-0602-0"},{"key":"0629_CR32","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1001\/jama.1992.03480170089035","volume":"267","author":"Hellman","year":"1992","unstructured":"Hellman DB. Spondyloarthropathy with hidradenitis suppurativa. JAMA 1992; 267:2363\u20132365.","journal-title":"JAMA"},{"key":"0629_CR33","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1002\/art.1780330401","volume":"33","author":"Schwartz","year":"1990","unstructured":"Schwartz B. Infectious agents. Immunity and rheumatic diseases. Arthritis Rheum 1990; 33:457\u2013465.","journal-title":"Arthritis Rheum"},{"key":"0629_CR34","first-page":"1302","volume":"23","author":"Kotilainen","year":"1996","unstructured":"Kotilainen P, Merilahti-Palo R, Lehtonen OP, et al. Case report. Propionibacterium acnes isolated from sternal osteitis in a patient with SAPHO syndrome. J Rheumatol 1996; 23:1302\u20131304.","journal-title":"J Rheumatol"},{"key":"0629_CR35","doi-asserted-by":"crossref","unstructured":"Kooijmans-Coutinho MF, Markusse HM, Dijkmans BAC. Infectious arthritis caused by Propionibacterium acnes: a report of two cases. Ann Rheum Dis 1989; 48:851\u2013852.","DOI":"10.1136\/ard.48.10.851"},{"key":"0629_CR36","first-page":"6","volume":"15","author":"Anneli","year":"1988","unstructured":"Anneli Savolainen H, Von Essen R, Anti J, Jahkola M. Propionibacterium acnes in purulent arthritis: probable cause of iatrogenic infection (letter). J Rheumatol 1988; 15:6.","journal-title":"J Rheumatol"},{"key":"0629_CR37","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1093\/clinids\/19.1.224","volume":"19","author":"Sulkowski","year":"1994","unstructured":"Sulkowski MS, Abonik IZ, Morris EI, Granger DL. Infectious arthritis due to Propionibacterium acnes in a prosthetic joint. Clin Infect Dis 1994; 19:224\u2013225.","journal-title":"Clin Infect Dis"},{"key":"0629_CR38","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1007\/BF01967078","volume":"11","author":"Suter","year":"1992","unstructured":"Suter F, Silanos MA, Tabacchi G, Maggiolo F. A case of Propionibacterium acnes spinal osteomyelitis. J Clin Microbiol Infect Dis 1992; 11:196\u2013197.","journal-title":"J Clin Microbiol Infect Dis"},{"key":"0629_CR39","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0002-9343(96)90016-9","volume":"100","author":"Honan","year":"1996","unstructured":"Honan M, White GW, Eisenberg GM. Spontaneous infectious diseases in adults. Am J Med 1996; 100:85\u201389.","journal-title":"Am J Med"},{"key":"0629_CR40","unstructured":"Wagner AD, Mai U, Hammer M, Zeidler H. Long term antibiotic therapy in patients with SAPHO syndrome (abstract). Arthritis Rheum 1997; 40(Suppl 9):562."},{"key":"0629_CR41","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1002\/1529-0131(199904)42:4<818::AID-ANR29>3.0.CO;2-G","volume":"42","author":"Ballara","year":"1999","unstructured":"Ballara SC, Siraj QH, Maini RN, Venables PJW. Sustained response to doxycycline therapy in two patients with SAPHO syndrome. Arthritis Rheum 1999; 42:819\u2013821.","journal-title":"Arthritis Rheum"},{"key":"0629_CR42","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1136\/ard.47.10.809","volume":"47","author":"Edlund","year":"1998","unstructured":"Edlund E, Johnsson U, Lidgren L, et al. Palmoplantar pustulosis and sterno-costo-clavicular arthro-osteitis. Ann Rheum Dis 1998; 47:809\u2013815.","journal-title":"Ann Rheum Dis"},{"key":"0629_CR43","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/S0049-0172(00)80020-7","volume":"29","author":"Rothschild","year":"2000","unstructured":"Rothschild B, Schils J, Lavelle H. Potential therapeutic approach to SAPHO. Semin Arthritis Rheum 2000; 29:332\u2013334.","journal-title":"Semin Arthritis Rheum"}],"container-title":["Skeletal Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00256-003-0629-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00256-003-0629-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00256-003-0629-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T15:45:07Z","timestamp":1558712707000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00256-003-0629-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,4,29]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2003,6]]}},"alternative-id":["0629"],"URL":"https:\/\/doi.org\/10.1007\/s00256-003-0629-x","relation":{},"ISSN":["0364-2348","1432-2161"],"issn-type":[{"value":"0364-2348","type":"print"},{"value":"1432-2161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,4,29]]}}}