{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T16:33:11Z","timestamp":1777134791284,"version":"3.51.4"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,3,4]],"date-time":"2011-03-04T00:00:00Z","timestamp":1299196800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skeletal Radiol"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1007\/s00256-011-1130-6","type":"journal-article","created":{"date-parts":[[2011,3,4]],"date-time":"2011-03-04T03:28:53Z","timestamp":1299209333000},"page":"75-81","source":"Crossref","is-referenced-by-count":14,"title":["Atypical diaphyseal femoral fractures\u2014new aspects"],"prefix":"10.1007","volume":"41","author":[{"given":"Frieda","family":"Feldman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,3,4]]},"reference":[{"issue":"19","key":"1130_CR1","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1056\/NEJMe1003064","volume":"362","author":"E Shane","year":"2010","unstructured":"Shane E. Evolving data about subtrochanteric fractures and bisphosphonates. N Engl J Med. 2010;362(19):1825\u20137.","journal-title":"N Engl J Med"},{"key":"1130_CR2","doi-asserted-by":"crossref","first-page":"4118","DOI":"10.1210\/jc.85.11.4118","volume":"85","author":"DM Black","year":"2000","unstructured":"Black DM, Thompson DE, Bauer DC, et al. Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. J Clin Endocrinol Metab. 2000;85:4118\u201324.","journal-title":"J Clin Endocrinol Metab"},{"key":"1130_CR3","doi-asserted-by":"crossref","first-page":"2927","DOI":"10.1001\/jama.296.24.2927","volume":"296","author":"DM Black","year":"2006","unstructured":"Black DM, Schwartz AV, Ensrud KE, et al. Effects of continuing or stopping alendronate after 5\u00a0years of treatment: the Fracture Intervention Trial Long-term Extension (FLEX): a randomized trial. JAMA. 2006;296:2927\u201338.","journal-title":"JAMA"},{"key":"1130_CR4","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.1016\/j.amjmed.2008.12.003","volume":"122","author":"JP Bilezikian","year":"2009","unstructured":"Bilezikian JP. Efficiency of bisphosphonates in reducing fracture risk in post menopausal osteoporosis. Am J Med. 2009;122:S14\u201321.","journal-title":"Am J Med"},{"key":"1130_CR5","doi-asserted-by":"crossref","first-page":"3109","DOI":"10.1210\/jc.85.9.3109","volume":"85","author":"RP Tomino","year":"2000","unstructured":"Tomino RP, Meunier PJ, Emkey R, et al. Skeletal benefits of alendronate: 7\u00a0year treatment of postmenopausal osteoporotic women. Phase III Osteoporosis Treatment Study Group. J Clin Endocrinol Metab. 2000;85:3109\u201315.","journal-title":"J Clin Endocrinol Metab"},{"key":"1130_CR6","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S8756-3282(03)00112-1","volume":"33","author":"YZ Bagger","year":"2003","unstructured":"Bagger YZ, Tanko LB, Alexandersen P, et al. Alendronate has a residual effect on bone mass in postmenopausal Danish women up to 7\u00a0years after treatment withdrawal. Bone. 2003;33:301\u20137.","journal-title":"Bone"},{"key":"1130_CR7","unstructured":"La Velle DG. Fractures of the hip. In: Canale ST, editor. Campbell\u2019s operative orthopaedics, vol. 3, 10th ed. St. Louis: Mosby 2002:2873\u2013938."},{"issue":"4","key":"1130_CR8","doi-asserted-by":"crossref","first-page":"413","DOI":"10.3109\/17453670903139914","volume":"80","author":"J Schilcher","year":"2009","unstructured":"Schilcher J, Aspenberg P. Incidence of stress fractures of the femoral shaft in women treated with bisphosphonate. Acta Orthop. 2009;80(4):413\u20135.","journal-title":"Acta Orthop"},{"key":"1130_CR9","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1056\/NEJMoa071408","volume":"357","author":"KG Saag","year":"2007","unstructured":"Saag KG, Shane E, Boonen S, et al. Teriparatide or alendronate in glucocorticoid induced osteoporosis. N Engl J Med. 2007;357:2028\u201339.","journal-title":"N Engl J Med"},{"key":"1130_CR10","first-page":"349","volume":"89B","author":"SK Goh","year":"2007","unstructured":"Goh SK, Yang KY, Koh JSB, et al. Subtrochanteric insufficiency fractures in patients on alendronate therapy: a caution. J Bone Joint Surg Br. 2007;89B:349\u201353.","journal-title":"J Bone Joint Surg Br"},{"key":"1130_CR11","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.injury.2007.08.036","volume":"39","author":"EB Kwek","year":"2008","unstructured":"Kwek EB, Goh SK, Bee Koh JS, et al. An emerging pattern of subtrochanteric stress fractures: a long-term complication of alendronate therapy? Injury. 2008;39:224\u201331.","journal-title":"Injury"},{"key":"1130_CR12","doi-asserted-by":"crossref","first-page":"2948","DOI":"10.1210\/jc.2007-2803","volume":"93","author":"M Visekruna","year":"2008","unstructured":"Visekruna M, Wilson D, McKiernan FE. Severely suppressed bone turnover and atypical skeletal fragility. J Clin Endocrinol Metab. 2008;93:2948\u201352.","journal-title":"J Clin Endocrinol Metab"},{"key":"1130_CR13","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1056\/NEJMc0707493","volume":"358","author":"BA Lenart","year":"2008","unstructured":"Lenart BA, Lorich DG, Lane JM. Atypical fractures of the femoral diaphysis, in postmenopausal woman taking alendronate. N Engl J Med. 2008;358:1304\u20136.","journal-title":"N Engl J Med"},{"key":"1130_CR14","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.2214\/AJR.09.3383","volume":"194","author":"JA Porrino Jr","year":"2010","unstructured":"Porrino Jr JA, Kohl CH, Taljanovic M, Rogers LF. Diagnosis of proximal femoral insufficiency fractures in patients receiving biophosphonate therapy. AJR Am J Roentgenol. 2010;194:1061\u20134.","journal-title":"AJR Am J Roentgenol"},{"key":"1130_CR15","first-page":"1","volume":"4","author":"LA Bush","year":"2009","unstructured":"Bush LA, Chew FS. Subtrochanteric femoral insufficiency fracture following bisphosphonate therapy for osseous metastasis. Radiol Case Rep. 2009;4:1.","journal-title":"Radiol Case Rep"},{"key":"1130_CR16","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.2214\/AJR.09.3588","volume":"194","author":"SS Chan","year":"2010","unstructured":"Chan SS, Rosenberg ZS, Chan K, et al. Subtrochanteric femoral fractures in patients receiving long term alendronate therapy: imaging features. A JR Am J Roentgenol. 2010;194:1581\u20136.","journal-title":"A JR Am J Roentgenol"},{"key":"1130_CR17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00523553","volume":"114","author":"F Pauwels","year":"1948","unstructured":"Pauwels F. Die Bedeutung der Bauprinzipien des Stutz- und Bewegungsapparates fur die Beanspruchung der Rohrenknochen. Anat Embryol. 1948;114:1\u20132.","journal-title":"Anat Embryol"},{"key":"1130_CR18","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1152\/ajplegacy.1961.200.6.1296","volume":"200","author":"H Fleisch","year":"1961","unstructured":"Fleisch H, Neuman WF. Mechanism of calcification: role of collagen polyphosphonates and phosphatase. Am J Physiol. 1961;200:1296\u2013300.","journal-title":"Am J Physiol"},{"key":"1130_CR19","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1152\/ajplegacy.1962.203.4.671","volume":"203","author":"H Fleisch","year":"1962","unstructured":"Fleisch H, Bisz S. Isolation from urine of pyrophosphates a calcification inhibitor. Am J Physiol. 1962;203:671\u20135.","journal-title":"Am J Physiol"},{"key":"1130_CR20","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1016\/B978-012098652-1.50180-3","volume-title":"Mechanism of action in bisphosphonates in principles of bone biology","author":"H Fleisch","year":"2002","unstructured":"Fleisch H. In: Bilezikian JP, Rodan GA, editors. Mechanism of action in bisphosphonates in principles of bone biology, vol. 1, 2nd ed. San Diego: Academic Press; 2002. p. 1361\u201385.","edition":"2"},{"issue":"3","key":"1130_CR21","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1210\/jc.2005-0057","volume":"90","author":"SM Ott","year":"2005","unstructured":"Ott SM. Editorial: long-term safety of bisphosphonates. J Clin Endocrinol Metab. 2005;90(3):1897\u20139.","journal-title":"J Clin Endocrinol Metab"},{"key":"1130_CR22","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1359\/jbmr.2000.15.4.613","volume":"15","author":"T Mashiba","year":"2000","unstructured":"Mashiba T, Hirano T, Turner CH, et al. Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib. J Bone Miner Res. 2000;15:613\u201320.","journal-title":"J Bone Miner Res"},{"issue":"3","key":"1130_CR23","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1210\/jc.2004-0952","volume":"90","author":"CV Odvina","year":"2005","unstructured":"Odvina CV, Zerwekh JE, et al. Severely suppressed bone turnover: a potential complication of alendronate therapy. J Clin Endocrinol Metab. 2005;90(3):1294\u2013301.","journal-title":"J Clin Endocrinol Metab"},{"key":"1130_CR24","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1359\/jbmr.1998.13.4.581","volume":"13","author":"SP Lackman","year":"1998","unstructured":"Lackman SP, Hughee DE, Coxon FB, et al. Nitrogen-containing bisphosphonates inhibit the mevolonate pathways and prevents posttranslational phenylnation of GTPbinding proteins including RAS. J Bone Miner Res. 1998;13:581\u20139.","journal-title":"J Bone Miner Res"},{"key":"1130_CR25","doi-asserted-by":"crossref","unstructured":"Weinstein RS, Roberson PK, Manalagas SC. Giant osteoclast formation and long term oral bisphosphonate therapy N Engl J Med 360;1:53\u201362.","DOI":"10.1056\/NEJMoa0802633"},{"key":"1130_CR26","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1359\/jbmr.1997.12.1.6","volume":"12","author":"DB Burr","year":"1997","unstructured":"Burr DB, Forwood MR, Fyhrie DP, et al. Perspective: bone microdamage and skeletal fragility in osteoporotic and stress fractures. J Bone Miner Res. 1997;12:6\u201315.","journal-title":"J Bone Miner Res"},{"key":"1130_CR27","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1172\/JCI119668","volume":"100","author":"PM Chavassieux","year":"1997","unstructured":"Chavassieux PM, Arlot ME, Reda C, et al. Histomorphometric assessment of longterm effects of alendronate on bone quality and remodeling in patients with osteoporosis. J Clin Invest. 1997;100:1475\u201380.","journal-title":"J Clin Invest"},{"key":"1130_CR28","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1056\/NEJMoa023110","volume":"349","author":"MP Whyte","year":"2003","unstructured":"Whyte MP, Wenkert D, Clements KL, et al. Bisphosphonate induced osteopetrosis. N Engl J Med. 2003;349:457\u201363.","journal-title":"N Engl J Med"}],"container-title":["Skeletal Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00256-011-1130-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00256-011-1130-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00256-011-1130-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,8]],"date-time":"2019-06-08T20:20:10Z","timestamp":1560025210000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00256-011-1130-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,4]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["1130"],"URL":"https:\/\/doi.org\/10.1007\/s00256-011-1130-6","relation":{},"ISSN":["0364-2348","1432-2161"],"issn-type":[{"value":"0364-2348","type":"print"},{"value":"1432-2161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,4]]}}}