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Each patient received MR arthrography and clinical examination at mid-term (range 22\u201336\u00a0months) and long term (range 96\u2013194\u00a0months) after surgery. MR arthrography was performed with dedicated coil and a 1.5-Tesla MR unit. The modified MOCART scale was used to evaluate the status of chondral implants. Implant coating, integration to the border zone, and the surface and structure of the repaired tissue were evaluated. Presence of bone marrow oedema was evaluated. The Cincinnati Knee Rating System (CKRS) was used for clinical assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At long term, 4\/26 patients had complete alignment; 5\/26 had a complete integration of the margins; in 4\/26 cases, the implant surface was undamaged; in 14\/26 cases, the reparative tissue was homogeneous. In 9\/26 cases, the implant showed isointense signal compared to articular cartilage, while the presence of subchondral bone oedema was documented in 19\/26 cases. The average radiological score decreased from 59.2 (mid-term) to 38.6 (long term). The average clinical score decreased from 8.9 to 8.3.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Decrease in clinical results was not significant (0.6 points<jats:italic>p<\/jats:italic>\u2009=\u2009.06), but mMOCART scores decreased significantly (<jats:italic>p<\/jats:italic>\u2009=\u2009.00003). Although imaging studies showed deterioration of the grafts, the patients did not have significant clinical deterioration (231\/250).<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00256-021-03775-y","type":"journal-article","created":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T09:38:33Z","timestamp":1618479513000},"page":"2079-2090","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Knee articular cartilage injury treatment with matrix-induced autologous chondrocyte implantation (MACI): correlation at 24 and 120\u00a0months between clinical and radiological findings using MR arthrography"],"prefix":"10.1007","volume":"50","author":[{"given":"Marco","family":"Calvi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Curti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0672-1573","authenticated-orcid":false,"given":"Christian","family":"Ossola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Duvia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Gloria","family":"Angeretti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Ronga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenio Annibale","family":"Genovese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,15]]},"reference":[{"key":"3775_CR1","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1056\/NEJM199410063311401","volume":"331","author":"M Brittberg","year":"1994","unstructured":"Brittberg M, Lindahl A, Nilsson A, Ohlsson C, Isaksson O, Peterson L. 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The approval for this specific study was obtained by the local institutional review board, according to the National Policy in the matter of Privacy Act on a retrospective analysis of anonymized data; informed consent, as stated by <i>Legge 22 Dicembre 2017 n.219 Gazzetta Ufficiale Della Repubblica Italiana<\/i>, was signed by each patient.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}