{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T03:10:32Z","timestamp":1774581032053,"version":"3.50.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T00:00:00Z","timestamp":1646006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T00:00:00Z","timestamp":1646006400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005722","name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005722","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Skeletal Radiol"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>Correct identification of adhesive capsulitis of the shoulder (ACS) has an important impact on adequate therapy. The aim of our study was to investigate the influence of intravenous contrast administration and of reader\u2019s experience on sensitivity and specificity of MRI in diagnosing ACS.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Materials and methods<\/jats:title>\n                <jats:p>A total of 180 patients were included in a retrospective study: 60 subjects with at least 4 of 5 clinical signs of adhesive capsulitis of the shoulder and 120 patients with other shoulder diseases who underwent contrast-enhanced MRI. In a first session, only non-enhanced images and in a second session also contrast-enhanced (CE) series were independently evaluated by three radiologists with various levels of professional experience. Readers were blinded to all clinical information and had to rate the shoulder MRIs for absence or presence of adhesive capsulitis. Data analysis included McNemar\u2019s test, <jats:italic>t<\/jats:italic> test, and <jats:italic>U<\/jats:italic> test (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Using non-enhanced MRI, readers achieved a mean sensitivity of 63.9% and a mean specificity of 86.4%. By additional use of CE sequences, the mean sensitivity (85.5%) and the sensitivity for each reader increased significantly (<jats:italic>p<\/jats:italic>\u2009=\u2009.046, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001, <jats:italic>p<\/jats:italic>\u2009=\u2009.045) while the improvement in mean specificity was not significant. Reader\u2019s experience had a positive effect on sensitivity and specificity, which was in part but not consistently significant.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The addition of CE sequences can significantly increase the sensitivity of MRI in the diagnosis of ACS. Reader\u2019s experience has shown to be another important factor for the diagnostic outcome.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00256-022-03994-x","type":"journal-article","created":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T04:26:41Z","timestamp":1646022401000},"page":"1807-1815","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["MR imaging detection of adhesive capsulitis of the shoulder: impact of intravenous contrast administration and reader\u2019s experience on diagnostic performance"],"prefix":"10.1007","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2669-2001","authenticated-orcid":false,"given":"Bernd","family":"Erber","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Hesse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Glaser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Baur-Melnyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophia","family":"Goller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Ricke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Heuck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,2,28]]},"reference":[{"issue":"2","key":"3994_CR1","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1016\/j.jse.2010.07.008","volume":"20","author":"JD Zuckerman","year":"2011","unstructured":"Zuckerman JD, Rokito A. Frozen shoulder: a consensus definition. J Shoulder Elbow Surg. 2011;20(2):322\u20135.","journal-title":"J Shoulder Elbow Surg"},{"issue":"8","key":"3994_CR2","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1007\/s00256-018-3139-6","volume":"48","author":"BKK Fields","year":"2019","unstructured":"Fields BKK, Skalski MR, Patel DB, White EA, Tomasian A, Gross JS, et al. Adhesive capsulitis: review of imaging findings, pathophysiology, clinical presentation, and treatment options. Skeletal Radiol. 2019;48(8):1171\u201384.","journal-title":"Skeletal Radiol"},{"issue":"2","key":"3994_CR3","first-page":"211","volume":"27","author":"JS Neviaser","year":"1945","unstructured":"Neviaser JS. Adhesive capsulitis of the shoulder: a study of the pathological findings in periarthritis of the shoulder. JBJS. 1945;27(2):211\u201322.","journal-title":"JBJS"},{"issue":"3","key":"3994_CR4","first-page":"210","volume":"79","author":"TD Bunker","year":"1997","unstructured":"Bunker TD. Frozen shoulder: unravelling the enigma. Ann R Coll Surg Engl. 1997;79(3):210\u20133.","journal-title":"Ann R Coll Surg Engl"},{"issue":"3","key":"3994_CR5","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1136\/ard.43.3.361","volume":"43","author":"AI Binder","year":"1984","unstructured":"Binder AI, Bulgen DY, Hazleman BL, Roberts S. Frozen shoulder: a long-term prospective study. Ann Rheum Dis. 1984;43(3):361\u20134.","journal-title":"Ann Rheum Dis"},{"key":"3994_CR6","doi-asserted-by":"crossref","unstructured":"Lundberg BJ. The frozen shoulder. Clinical and radiographical observations. The effect of manipulation under general anesthesia. Structure and glycosaminoglycan content of the joint capsule. Local bone metabolism. Acta Orthop Scand Suppl. 1969; 119:1\u201359.","DOI":"10.3109\/ort.1969.40.suppl-119.01"},{"issue":"2","key":"3994_CR7","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1007\/s11420-008-9088-1","volume":"4","author":"CM Sofka","year":"2008","unstructured":"Sofka CM, Ciavarra GA, Hannafin JA, Cordasco FA, Potter HG. Magnetic resonance imaging of adhesive capsulitis: correlation with clinical staging. HSS J. 2008;4(2):164\u20139.","journal-title":"HSS J"},{"key":"3994_CR8","doi-asserted-by":"crossref","unstructured":"Neviaser RJ, Neviaser TJ. The frozen shoulder. Diagnosis and management. Clin Orthop Relat Res. 1987(223):59\u201364.","DOI":"10.1097\/00003086-198710000-00008"},{"issue":"1","key":"3994_CR9","doi-asserted-by":"publisher","first-page":"26","DOI":"10.32098\/mltj.01.2016.04","volume":"6","author":"NH Zreik","year":"2016","unstructured":"Zreik NH, Malik RA, Charalambous CP. Adhesive capsulitis of the shoulder and diabetes: a meta-analysis of prevalence. Muscles Ligaments Tendons J. 2016;6(1):26\u201334.","journal-title":"Muscles Ligaments Tendons J"},{"key":"3994_CR10","doi-asserted-by":"crossref","unstructured":"Akbar M, McLean M, Garcia-Melchor E, Crowe LA, McMillan P, Fazzi UG, et al. Fibroblast activation and inflammation in frozen shoulder. PLoS One. 2019; 14(4):e0215301.","DOI":"10.1371\/journal.pone.0215301"},{"issue":"6","key":"3994_CR11","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1016\/j.clinimag.2015.08.006","volume":"39","author":"KS Ahn","year":"2015","unstructured":"Ahn KS, Kang CH, Kim Y, Jeong WK. Diagnosis of adhesive capsulitis: comparison of contrast-enhanced MRI with noncontrast-enhanced MRI. Clin Imaging. 2015;39(6):1061\u20137.","journal-title":"Clin Imaging"},{"issue":"8","key":"3994_CR12","doi-asserted-by":"publisher","first-page":"2100","DOI":"10.1007\/s00330-002-1349-7","volume":"12","author":"D Connell","year":"2002","unstructured":"Connell D, Padmanabhan R, Buchbinder R. Adhesive capsulitis: role of MR imaging in differential diagnosis. Eur Radiol. 2002;12(8):2100\u20136.","journal-title":"Eur Radiol"},{"issue":"3","key":"3994_CR13","doi-asserted-by":"publisher","first-page":"577","DOI":"10.2214\/AJR.10.4683","volume":"195","author":"JM Polster","year":"2010","unstructured":"Polster JM, Schickendantz MS. Shoulder MRI: what do we miss? AJR Am J Roentgenol. 2010;195(3):577\u201384.","journal-title":"AJR Am J Roentgenol"},{"key":"3994_CR14","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.clinimag.2017.04.002","volume":"44","author":"AS Chi","year":"2017","unstructured":"Chi AS, Kim J, Long SS, Morrison WB, Zoga AC. Non-contrast MRI diagnosis of adhesive capsulitis of the shoulder. Clin Imaging. 2017;44:46\u201350.","journal-title":"Clin Imaging"},{"issue":"2","key":"3994_CR15","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1007\/s00330-018-5604-y","volume":"29","author":"CH Suh","year":"2019","unstructured":"Suh CH, Yun SJ, Jin W, Lee SH, Park SY, Park JS, et al. Systematic review and meta-analysis of magnetic resonance imaging features for diagnosis of adhesive capsulitis of the shoulder. Eur Radiol. 2019;29(2):566\u201377.","journal-title":"Eur Radiol"},{"issue":"11","key":"3994_CR16","doi-asserted-by":"publisher","first-page":"5981","DOI":"10.1007\/s00330-020-07003-4","volume":"30","author":"E Pessis","year":"2020","unstructured":"Pessis E, Mihoubi F, Feydy A, Campagna R, Guerini H, Roren A, et al. Usefulness of intravenous contrast-enhanced MRI for diagnosis of adhesive capsulitis. Eur Radiol. 2020;30(11):5981\u201391.","journal-title":"Eur Radiol"},{"issue":"8","key":"3994_CR17","doi-asserted-by":"publisher","first-page":"1886","DOI":"10.1007\/s11999-016-4732-4","volume":"474","author":"MD Kohn","year":"2016","unstructured":"Kohn MD, Sassoon AA, Fernando ND. Classifications in brief: Kellgren-Lawrence classification of osteoarthritis. Clin Orthop Relat Res. 2016;474(8):1886\u201393.","journal-title":"Clin Orthop Relat Res"},{"issue":"1","key":"3994_CR18","doi-asserted-by":"publisher","first-page":"173","DOI":"10.2214\/AJR.10.6173","volume":"198","author":"SY Lee","year":"2012","unstructured":"Lee SY, Park J, Song SW. Correlation of MR arthrographic findings and range of shoulder motions in patients with frozen shoulder. AJR Am J Roentgenol. 2012;198(1):173\u20139.","journal-title":"AJR Am J Roentgenol"},{"issue":"12","key":"3994_CR19","doi-asserted-by":"publisher","first-page":"2415","DOI":"10.1007\/s00330-005-2830-x","volume":"15","author":"MM Lefevre-Colau","year":"2005","unstructured":"Lefevre-Colau MM, Drape JL, Fayad F, Rannou F, Diche T, Minvielle F, et al. Magnetic resonance imaging of shoulders with idiopathic adhesive capsulitis: reliability of measures. Eur Radiol. 2005;15(12):2415\u201322.","journal-title":"Eur Radiol"},{"issue":"4","key":"3994_CR20","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s00256-018-3064-8","volume":"48","author":"J Park","year":"2019","unstructured":"Park J, Choi YH, Chai JW, Cha SW, Lim JH, Jo CH, et al. Anterior capsular abnormality: another important MRI finding for the diagnosis of adhesive capsulitis of the shoulder. Skeletal Radiol. 2019;48(4):543\u201352.","journal-title":"Skeletal Radiol"},{"key":"3994_CR21","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.2214\/ajr.164.6.7754892","volume":"164","author":"EW Emig","year":"1995","unstructured":"Emig EW, Schweitzer ME, Karasick D, Lubowitz J. Adhesive capsulitis of the shoulder: MR diagnosis. AJR Am J Roentgenol. 1995;164:1457\u20139.","journal-title":"AJR Am J Roentgenol"},{"issue":"2","key":"3994_CR22","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1177\/1758573216676786","volume":"9","author":"HV Le","year":"2017","unstructured":"Le HV, Lee SJ, Nazarian A, Rodriguez EK. Adhesive capsulitis of the shoulder: review of pathophysiology and current clinical treatments. Shoulder Elbow. 2017;9(2):75\u201384.","journal-title":"Shoulder Elbow"},{"issue":"10","key":"3994_CR23","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1007\/s00256-012-1391-8","volume":"41","author":"KS Ahn","year":"2012","unstructured":"Ahn KS, Kang CH, Oh YW, Jeong WK. Correlation between magnetic resonance imaging and clinical impairment in patients with adhesive capsulitis. Skeletal Radiol. 2012;41(10):1301\u20138.","journal-title":"Skeletal Radiol"},{"issue":"6","key":"3994_CR24","doi-asserted-by":"publisher","first-page":"W589","DOI":"10.2214\/AJR.11.7453","volume":"198","author":"PA Gondim Teixeira","year":"2012","unstructured":"Gondim Teixeira PA, Balaj C, Chanson A, Lecocq S, Louis M, Blum A. Adhesive capsulitis of the shoulder: value of inferior glenohumeral ligament signal changes on T2-weighted fat-saturated images. AJR Am J Roentgenol. 2012;198(6):W589-596.","journal-title":"AJR Am J Roentgenol"},{"issue":"1","key":"3994_CR25","doi-asserted-by":"publisher","first-page":"159","DOI":"10.2307\/2529310","volume":"33","author":"JR Landis","year":"1977","unstructured":"Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33(1):159\u201374.","journal-title":"Biometrics"},{"issue":"2","key":"3994_CR26","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1148\/radiol.2332031219","volume":"233","author":"B Mengiardi","year":"2004","unstructured":"Mengiardi B, Pfirrmann CW, Gerber C, Hodler J, Zanetti M. Frozen shoulder: MR arthrographic findings. Radiology. 2004;233(2):486\u201392.","journal-title":"Radiology"},{"issue":"6","key":"3994_CR27","doi-asserted-by":"publisher","first-page":"W1105","DOI":"10.2214\/AJR.10.6099","volume":"197","author":"KD Song","year":"2011","unstructured":"Song KD, Kwon JW, Yoon YC, Choi SH. Indirect MR arthrographic findings of adhesive capsulitis. AJR Am J Roentgenol. 2011;197(6):W1105-1109.","journal-title":"AJR Am J Roentgenol"},{"issue":"1","key":"3994_CR28","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1148\/radiology.187.1.8451409","volume":"187","author":"CS Winalski","year":"1993","unstructured":"Winalski CS, Aliabadi P, Wright RJ, Shortkroff S, Sledge CB, Weissman BN. Enhancement of joint fluid with intravenously administered gadopentetate dimeglumine: technique, rationale, and implications. Radiology. 1993;187(1):179\u201385.","journal-title":"Radiology"},{"issue":"12","key":"3994_CR29","doi-asserted-by":"publisher","first-page":"e372","DOI":"10.1016\/j.jse.2018.05.042","volume":"27","author":"H Sasanuma","year":"2018","unstructured":"Sasanuma H, Sugimoto H, Iijima Y, Kanaya Y, Saito T, Takeshita K. Blood flow evaluation by dynamic magnetic resonance imaging of symptomatic rotator cuff tears and frozen shoulders. J Shoulder Elbow Surg. 2018;27(12):e372\u20139.","journal-title":"J Shoulder Elbow Surg"}],"container-title":["Skeletal Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00256-022-03994-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00256-022-03994-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00256-022-03994-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T09:06:14Z","timestamp":1657789574000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00256-022-03994-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,28]]},"references-count":29,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["3994"],"URL":"https:\/\/doi.org\/10.1007\/s00256-022-03994-x","relation":{},"ISSN":["0364-2348","1432-2161"],"issn-type":[{"value":"0364-2348","type":"print"},{"value":"1432-2161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,28]]},"assertion":[{"value":"11 November 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 January 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 January 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}