{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T23:39:55Z","timestamp":1783381195996,"version":"3.54.6"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T00:00:00Z","timestamp":1671753600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T00:00:00Z","timestamp":1671753600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Skeletal Radiol"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1007\/s00256-022-04260-w","type":"journal-article","created":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T10:04:07Z","timestamp":1671789847000},"page":"1599-1604","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Assessing tophaceous spinal gout treatment response using dual-energy CT as a point-of-care imaging modality: case report"],"prefix":"10.1007","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4649-7628","authenticated-orcid":false,"given":"Mohammadali","family":"Saffarzadeh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed M. A.","family":"Haydar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamran","family":"Shojania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugue","family":"Ouellette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Savvas","family":"Nicolaou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,12,23]]},"reference":[{"key":"4260_CR1","first-page":"533","volume":"102","author":"KT Clebak","year":"2020","unstructured":"Clebak KT, Morrison A, Croad JR. Gout: rapid evidence review. Am Fam Physician. 2020;102:533\u20138.","journal-title":"Am Fam Physician"},{"key":"4260_CR2","doi-asserted-by":"publisher","first-page":"R160","DOI":"10.1186\/ar4343","volume":"15","author":"A Rajan","year":"2013","unstructured":"Rajan A, Aati O, Kalluru R, Gamble GD, Horne A, Doyle AJ, et al. Lack of change in urate deposition by dual-energy computed tomography among clinically stable patients with long-standing tophaceous gout: a prospective longitudinal study. Arthritis Res Ther. 2013;15:R160.","journal-title":"Arthritis Res Ther"},{"key":"4260_CR3","first-page":"942","volume":"118","author":"M B\u0103dulescu","year":"2014","unstructured":"B\u0103dulescu M, Macovei L, Rezu\u015f E. Acute gout attack with normal serum uric acid levels. Rev Med Chir Soc Med Nat Iasi. 2014;118:942\u20135.","journal-title":"Rev Med Chir Soc Med Nat Iasi"},{"key":"4260_CR4","first-page":"e985","volume":"9","author":"D Jayakumar","year":"2017","unstructured":"Jayakumar D, Sehra ST, Anand S, Stallings GW, Danve A. Role of dual energy computed tomography imaging in the diagnosis of gout. Cureus. 2017;9:e985.","journal-title":"Cureus"},{"key":"4260_CR5","doi-asserted-by":"publisher","first-page":"S17","DOI":"10.1016\/j.semarthrit.2020.04.009","volume":"50","author":"W Abdellatif","year":"2020","unstructured":"Abdellatif W, Ding J, Khorshed D, Shojania K, Nicolaou S. Unravelling the mysteries of gout by multimodality imaging. Semin Arthritis Rheum. 2020;50:S17-23.","journal-title":"Semin Arthritis Rheum"},{"key":"4260_CR6","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1136\/annrheumdis-2015-208237","volume":"74","author":"T Neogi","year":"2015","unstructured":"Neogi T, Jansen TLTA, Dalbeth N, Fransen J, Schumacher HR, Berendsen D, et al. 2015 Gout classification criteria: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative. Ann Rheum Dis. 2015;74:1789\u201398.","journal-title":"Ann Rheum Dis"},{"key":"4260_CR7","doi-asserted-by":"publisher","first-page":"S78","DOI":"10.2214\/AJR.12.9117","volume":"199","author":"S Nicolaou","year":"2012","unstructured":"Nicolaou S, Liang T, Murphy DT, Korzan JR, Ouellette H, Munk P. Dual-energy CT: a promising new technique for assessment of the musculoskeletal system. AJR Am J Roentgenol. 2012;199:S78-86.","journal-title":"AJR Am J Roentgenol"},{"key":"4260_CR8","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1111\/1756-185X.12634","volume":"18","author":"Y Sun","year":"2015","unstructured":"Sun Y, Chen H, Zhang Z, Ma L, Zhou J, Zhou Y, et al. Dual-energy computed tomography for monitoring the effect of urate-lowering therapy in gouty arthritis. Int J Rheum Dis. 2015;18:880\u20135.","journal-title":"Int J Rheum Dis"},{"key":"4260_CR9","doi-asserted-by":"publisher","first-page":"166","DOI":"10.3390\/jcm11010166","volume":"11","author":"JS Weaver","year":"2021","unstructured":"Weaver JS, Vina ER, Munk PL, Klauser AS, Elifritz JM, Taljanovic MS. Gouty arthropathy: review of clinical manifestations and treatment, with emphasis on imaging. J Clin Med. 2021;11:166.","journal-title":"J Clin Med"},{"key":"4260_CR10","doi-asserted-by":"crossref","unstructured":"Dalbeth N, Becce F, Botson JK, Zhao L, Kumar A. Dual-energy CT assessment of rapid monosodium urate depletion and bone erosion remodelling during pegloticase plus methotrexate co-therapy. Rheumatol Oxf Engl. 2022;61:4898\u2013904.","DOI":"10.1093\/rheumatology\/keac173"},{"key":"4260_CR11","doi-asserted-by":"publisher","first-page":"e000075","DOI":"10.1136\/rmdopen-2015-000075","volume":"1","author":"EG Araujo","year":"2015","unstructured":"Araujo EG, Bayat S, Petsch C, Englbrecht M, Faustini F, Kleyer A, et al. Tophus resolution with pegloticase: a prospective dual-energy CT study. RMD Open. 2015;1:e000075.","journal-title":"RMD Open"},{"issue":"5","key":"4260_CR12","first-page":"1365","volume":"31","author":"MA Desai","year":"2011","unstructured":"Desai MA, Peterson JJ, Garner HW, Kransdorf MJ. Clinical utility of dual-energy CT for evaluation of tophaceous gout. Radiogr Rev Publ Radiol Soc N Am Inc. 2011;31(5):1365\u201375.","journal-title":"Radiogr Rev Publ Radiol Soc N Am Inc"},{"key":"4260_CR13","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/s00296-009-1295-7","volume":"32","author":"AK Bacani","year":"2012","unstructured":"Bacani AK, McCollough CH, Glazebrook KN, Bond JR, Michet CJ, Milks J, et al. Dual energy computed tomography for quantification of tissue urate deposits in tophaceous gout: help from modern physics in the management of an ancient disease. Rheumatol Int. 2012;32:235\u20139.","journal-title":"Rheumatol Int"},{"key":"4260_CR14","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1177\/1759720X14542960","volume":"6","author":"PV Chowalloor","year":"2014","unstructured":"Chowalloor PV, Siew TK, Keen HI. Imaging in gout: a review of the recent developments. Ther Adv Musculoskelet Dis. 2014;6:131\u201343.","journal-title":"Ther Adv Musculoskelet Dis"},{"key":"4260_CR15","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.2214\/AJR.09.2428","volume":"194","author":"S Nicolaou","year":"2010","unstructured":"Nicolaou S, Yong-Hing CJ, Galea-Soler S, Hou DJ, Louis L, Munk P. Dual-energy CT as a potential new diagnostic tool in the management of gout in the acute setting. AJR Am J Roentgenol. 2010;194:1072\u20138.","journal-title":"AJR Am J Roentgenol"},{"key":"4260_CR16","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1007\/s00256-018-2948-y","volume":"47","author":"Z Yu","year":"2018","unstructured":"Yu Z, Mao T, Xu Y, Li T, Wang Y, Gao F, et al. Diagnostic accuracy of dual-energy CT in gout: a systematic review and meta-analysis. Skeletal Radiol. 2018;47:1587\u201393.","journal-title":"Skeletal Radiol"},{"key":"4260_CR17","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1001\/jamacardio.2019.3201","volume":"4","author":"AS Klauser","year":"2019","unstructured":"Klauser AS, Halpern EJ, Strobl S, Gruber J, Feuchtner G, Bellmann-Weiler R, et al. Dual-energy computed tomography detection of cardiovascular monosodium urate deposits in patients with gout. JAMA Cardiol. 2019;4:1019\u201328.","journal-title":"JAMA Cardiol"},{"key":"4260_CR18","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.1016\/j.acra.2007.09.016","volume":"14","author":"AN Primak","year":"2007","unstructured":"Primak AN, Fletcher JG, Vrtiska TJ, Dzyubak OP, Lieske JC, Jackson ME, et al. Noninvasive differentiation of uric acid versus non-uric acid kidney stones using dual-energy CT. Acad Radiol. 2007;14:1441\u20137.","journal-title":"Acad Radiol"},{"key":"4260_CR19","doi-asserted-by":"publisher","first-page":"367","DOI":"10.5144\/0256-4947.2016.367","volume":"36","author":"S Xu","year":"2016","unstructured":"Xu S, Li F, Xie X. Identification of gout in unusual sites by dual energy computed tomography. Ann Saudi Med. 2016;36:367\u20138.","journal-title":"Ann Saudi Med"},{"key":"4260_CR20","doi-asserted-by":"publisher","first-page":"4135","DOI":"10.1016\/j.radcr.2022.08.009","volume":"17","author":"P Brahmbhatt","year":"2022","unstructured":"Brahmbhatt P, Vibhute P, Gupta V, Murray J, Desai A, Agarwal A. Spinal gout diagnosed by dual-energy CT: a case report. Radiol Case Rep. 2022;17:4135\u20138.","journal-title":"Radiol Case Rep"},{"key":"4260_CR21","first-page":"50","volume":"7","author":"W Ng","year":"2017","unstructured":"Ng W, Sin CH, Wong CH, Chiu WF, Chung OM. Unusual presentation of spinal gout: 2 cases report and literature review. J Orthop Case Rep. 2017;7:50\u20134.","journal-title":"J Orthop Case Rep"},{"key":"4260_CR22","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.carj.2018.06.003","volume":"69","author":"B Gong","year":"2018","unstructured":"Gong B, Shojania K, Khosa F, Nicolaou S. Referral Patterns for dual-energy computed tomography in diagnosis and management of gout: ten-year experience at a Canadian institution. Can Assoc Radiol J. 2018;69:430\u20136.","journal-title":"Can Assoc Radiol J"},{"key":"4260_CR23","doi-asserted-by":"publisher","first-page":"SI81","DOI":"10.1093\/rheumatology\/keab533","volume":"61","author":"T Uhlig","year":"2022","unstructured":"Uhlig T, Eskild T, Karoliussen LF, Sexton J, Kvien TK, Haavardsholm EA, et al. Two-year reduction of dual-energy CT urate depositions during a treat-to-target strategy in gout in the NOR-Gout longitudinal study. Rheumatol. 2022;61:SI81-5.","journal-title":"Rheumatol"},{"key":"4260_CR24","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1007\/s10067-014-2606-2","volume":"33","author":"H Wu","year":"2014","unstructured":"Wu H, Xue J, Ye L, Zhou Q, Shi D, Xu R. The application of dual-energy computed tomography in the diagnosis of acute gouty arthritis. Clin Rheumatol. 2014;33:975\u20139.","journal-title":"Clin Rheumatol"},{"key":"4260_CR25","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1002\/art.20935","volume":"52","author":"MA Becker","year":"2005","unstructured":"Becker MA, Schumacher HR, Wortmann RL, MacDonald PA, Palo WA, Eustace D, et al. Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase: a twenty-eight-day, multicenter, phase II, randomized, double-blind, placebo-controlled, dose-response clinical trial examining safety and efficacy in patients with gout. Arthritis Rheum. 2005;52:916\u201323.","journal-title":"Arthritis Rheum"},{"key":"4260_CR26","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1136\/ard.2008.099713","volume":"68","author":"HK Choi","year":"2009","unstructured":"Choi HK, Al-Arfaj AM, Eftekhari A, Munk PL, Shojania K, Reid G, et al. Dual energy computed tomography in tophaceous gout. Ann Rheum Dis. 2009;68:1609\u201312.","journal-title":"Ann Rheum Dis"}],"container-title":["Skeletal Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00256-022-04260-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00256-022-04260-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00256-022-04260-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,17]],"date-time":"2023-06-17T06:04:02Z","timestamp":1686981842000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00256-022-04260-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,23]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["4260"],"URL":"https:\/\/doi.org\/10.1007\/s00256-022-04260-w","relation":{},"ISSN":["0364-2348","1432-2161"],"issn-type":[{"value":"0364-2348","type":"print"},{"value":"1432-2161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,23]]},"assertion":[{"value":"28 September 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 December 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 December 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Informed consent was obtained from the subject described in this report.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}